Published in Invest Ophthalmol Vis Sci on April 01, 2006
Focal adhesion kinase (FAK)-related non-kinase inhibits myofibroblast differentiation through differential MAPK activation in a FAK-dependent manner. J Biol Chem (2008) 1.42
Mast cells promote airway smooth muscle cell differentiation via autocrine up-regulation of TGF-beta 1. J Immunol (2008) 1.34
A TRPC6-dependent pathway for myofibroblast transdifferentiation and wound healing in vivo. Dev Cell (2012) 1.29
Myofibroblasts: trust your heart and let fate decide. J Mol Cell Cardiol (2013) 1.25
Localization of TGF-beta type II receptor and ED-A fibronectin in normal conjunctiva and failed filtering blebs. Mol Vis (2008) 1.01
Maternal obesity induces fibrosis in fetal myocardium of sheep. Am J Physiol Endocrinol Metab (2010) 0.96
Differential transcriptional analysis between red and white skeletal muscle of Chinese Meishan pigs. Int J Biol Sci (2010) 0.95
CLIC4 regulates TGF-β-dependent myofibroblast differentiation to produce a cancer stroma. Oncogene (2013) 0.93
Reversal of myofibroblasts by amniotic membrane stromal extract. J Cell Physiol (2008) 0.92
Enhanced transforming growth factor-beta signaling and fibrogenesis in ovine fetal skeletal muscle of obese dams at late gestation. Am J Physiol Endocrinol Metab (2010) 0.91
Hyaluronan synthesis mediates the fibrotic response of keratocytes to transforming growth factor beta. J Biol Chem (2010) 0.90
Tgfbeta signaling directly induces Arf promoter remodeling by a mechanism involving Smads 2/3 and p38 MAPK. J Biol Chem (2010) 0.89
Akt1 mediates α-smooth muscle actin expression and myofibroblast differentiation via myocardin and serum response factor. J Biol Chem (2013) 0.88
Evaluation of filtering blebs exhibiting transconjunctival oozing using anterior segment optical coherence tomography. Graefes Arch Clin Exp Ophthalmol (2014) 0.84
Stromal expression of heat-shock protein 27 is associated with worse clinical outcome in patients with colorectal cancer lung metastases. PLoS One (2015) 0.83
Molecular networks underlying myofibroblast fate and fibrosis. J Mol Cell Cardiol (2016) 0.81
Prostaglandin E2 inhibits α-smooth muscle actin transcription during myofibroblast differentiation via distinct mechanisms of modulation of serum response factor and myocardin-related transcription factor-A. J Biol Chem (2014) 0.81
Fibroblast-to-myofibroblast switch is mediated by NAD(P)H oxidase generated reactive oxygen species. Biosci Rep (2014) 0.80
Adiponectin attenuates lung fibroblasts activation and pulmonary fibrosis induced by paraquat. PLoS One (2015) 0.80
Cardiac valve cells and their microenvironment--insights from in vitro studies. Nat Rev Cardiol (2014) 0.79
The role of focal adhesion kinase in the TGF-β-induced myofibroblast transdifferentiation of human Tenon's fibroblasts. Korean J Ophthalmol (2012) 0.79
Rosiglitazone inhibits TGF-β 1 induced activation of human Tenon fibroblasts via p38 signal pathway. PLoS One (2014) 0.79
Fibroblast-Specific Genetic Manipulation of p38 MAPK in vivo Reveals its Central Regulatory Role in Fibrosis. Circulation (2017) 0.78
Sphingosine kinase 1 is required for TGF-β mediated fibroblastto- myofibroblast differentiation in ovarian cancer. Oncotarget (2016) 0.78
Identification of P-Rex1 as an anti-inflammatory and anti-fibrogenic target for pulmonary fibrosis. Sci Rep (2016) 0.77
Redox-sensitive MAPK and Notch3 regulate fibroblast differentiation and activation: a dual role of ERK1/2. Oncotarget (2016) 0.77
Roles of transforming growth factor-β1 and OB-cadherin in porcine cardiac valve myofibroblast differentiation. FASEB J (2014) 0.77
The p38 mitogen-activated protein kinases modulate endothelial cell survival and tissue repair. Inflamm Res (2011) 0.77
Endotoxin-induced endothelial fibrosis is dependent on expression of transforming growth factors β1 and β2. Infect Immun (2014) 0.77
Pro-fibrotic pathway activation in trabecular meshwork and lamina cribrosa is the main driving force of glaucoma. Cell Cycle (2016) 0.76
Control of fibrotic changes through the synergistic effects of anti-fibronectin antibody and an RGDS-tagged form of the same antibody. Sci Rep (2016) 0.76
FGF2-mediated attenuation of myofibroblast activation is modulated by distinct MAPK signaling pathways in human dermal fibroblasts. J Dermatol Sci (2017) 0.75
Ghrelin Inhibits Post-Operative Adhesions via Blockage of the TGF-β Signaling Pathway. PLoS One (2016) 0.75
Signal transduction of bone morphogenetic protein receptors. Cell Signal (2004) 3.11
The mode of bone morphogenetic protein (BMP) receptor oligomerization determines different BMP-2 signaling pathways. J Biol Chem (2001) 2.59
Recent advances in BMP receptor signaling. Cytokine Growth Factor Rev (2009) 2.57
Factors affecting the outcome of trabeculectomy: an analysis based on combined data from two phase III studies of an antibody to transforming growth factor beta2, CAT-152. Ophthalmology (2007) 2.19
Intracorneal hematoma after canaloplasty and clear cornea phacoemulsification: surgical management. Eur J Ophthalmol (2012) 2.06
Different routes of bone morphogenic protein (BMP) receptor endocytosis influence BMP signaling. Mol Cell Biol (2006) 1.99
Activating and deactivating mutations in the receptor interaction site of GDF5 cause symphalangism or brachydactyly type A2. J Clin Invest (2005) 1.88
Of flies, mice and men: a systematic approach to understanding the early life origins of chronic lung disease. Thorax (2012) 1.88
Intraocular pressure measurement-comparison of dynamic contour tonometry and goldmann applanation tonometry. J Glaucoma (2006) 1.84
Crystal structure analysis reveals how the Chordin family member crossveinless 2 blocks BMP-2 receptor binding. Dev Cell (2008) 1.82
The Prevalence of Visual Impairment in Retirement Home Residents. Dtsch Arztebl Int (2016) 1.74
Molecular recognition of BMP-2 and BMP receptor IA. Nat Struct Mol Biol (2004) 1.65
Crossveinless 2 is an essential positive feedback regulator of Bmp signaling during zebrafish gastrulation. Development (2006) 1.57
Mutations in bone morphogenetic protein receptor 1B cause brachydactyly type A2. Proc Natl Acad Sci U S A (2003) 1.52
A single residue of GDF-5 defines binding specificity to BMP receptor IB. J Mol Biol (2005) 1.49
Structure of the bone morphogenetic protein receptor ALK2 and implications for fibrodysplasia ossificans progressiva. J Biol Chem (2012) 1.43
Dysregulated bone morphogenetic protein signaling in monocrotaline-induced pulmonary arterial hypertension. Arterioscler Thromb Vasc Biol (2007) 1.43
BMPs: from bone to body morphogenetic proteins. Sci Signal (2010) 1.41
MicroRNAs differentially expressed in postnatal aortic development downregulate elastin via 3' UTR and coding-sequence binding sites. PLoS One (2011) 1.41
von Willebrand factor type C domain-containing proteins regulate bone morphogenetic protein signaling through different recognition mechanisms. J Biol Chem (2007) 1.38
Intricacies of BMP receptor assembly. Cytokine Growth Factor Rev (2009) 1.35
A silent H-bond can be mutationally activated for high-affinity interaction of BMP-2 and activin type IIB receptor. BMC Struct Biol (2007) 1.25
Structure, binding, and antagonists in the IL-4/IL-13 receptor system. Biochim Biophys Acta (2002) 1.25
Integration of the TGF-beta pathway into the cellular signalling network. Cell Signal (2002) 1.23
Dynamics and interaction of caveolin-1 isoforms with BMP-receptors. J Cell Sci (2005) 1.21
A portrait of Transforming Growth Factor β superfamily signalling: Background matters. Int J Biochem Cell Biol (2011) 1.21
Proteins associated with type II bone morphogenetic protein receptor (BMPR-II) and identified by two-dimensional gel electrophoresis and mass spectrometry. Proteomics (2004) 1.20
Immunoselection of breast and ovarian cancer cells with trastuzumab and natural killer cells: selective escape of CD44high/CD24low/HER2low breast cancer stem cells. Cancer Res (2009) 1.19
Initiation of Smad-dependent and Smad-independent signaling via distinct BMP-receptor complexes. J Bone Joint Surg Am (2003) 1.18
Homomeric and heteromeric complexes among TGF-β and BMP receptors and their roles in signaling. Cell Signal (2011) 1.18
A phase III study of subconjunctival human anti-transforming growth factor beta(2) monoclonal antibody (CAT-152) to prevent scarring after first-time trabeculectomy. Ophthalmology (2007) 1.18
Encoding of motor skill in the corticomuscular system of musicians. Curr Biol (2010) 1.14
Substrate rigidity modulates cell matrix interactions and protein expression in human trabecular meshwork cells. Invest Ophthalmol Vis Sci (2008) 1.14
Case reports of PML in patients treated for psoriasis. N Engl J Med (2013) 1.13
Transforming growth factor-beta1 reduces megalin- and cubilin-mediated endocytosis of albumin in proximal-tubule-derived opossum kidney cells. J Physiol (2003) 1.13
Crystal structure analysis reveals a spring-loaded latch as molecular mechanism for GDF-5-type I receptor specificity. EMBO J (2009) 1.13
Kinetics of antigen binding to antibody microspots: strong limitation by mass transport to the surface. Proteomics (2006) 1.13
Sumoylation of the transcription factor NFATc1 leads to its subnuclear relocalization and interleukin-2 repression by histone deacetylase. J Biol Chem (2009) 1.13
Noggin. Int J Biochem Cell Biol (2011) 1.12
Receptor oligomerization and beyond: a case study in bone morphogenetic proteins. BMC Biol (2009) 1.12
The high-affinity interaction of human IL-4 and the receptor alpha chain is constituted by two independent binding clusters. J Mol Biol (2002) 1.11
Contractility as a prerequisite for TGF-beta-induced myofibroblast transdifferentiation in human tenon fibroblasts. Invest Ophthalmol Vis Sci (2006) 1.11
Mutations in GDF5 reveal a key residue mediating BMP inhibition by NOGGIN. PLoS Genet (2009) 1.09
Type I receptor binding of bone morphogenetic protein 6 is dependent on N-glycosylation of the ligand. FEBS J (2007) 1.09
Characteristic gene expression profile of primary human cerebral endothelial cells. FASEB J (2002) 1.07
Lovastatin inhibits TGF-beta-induced myofibroblast transdifferentiation in human tenon fibroblasts. Invest Ophthalmol Vis Sci (2008) 1.07
A novel R486Q mutation in BMPR1B resulting in either a brachydactyly type C/symphalangism-like phenotype or brachydactyly type A2. Eur J Hum Genet (2006) 1.07
Modulation of GDF5/BRI-b signalling through interaction with the tyrosine kinase receptor Ror2. Genes Cells (2004) 1.03
Comparison of phacotrabeculectomy versus phacocanaloplasty in the treatment of patients with concomitant cataract and glaucoma. BMC Ophthalmol (2013) 1.03
Localization of TGF-beta type II receptor and ED-A fibronectin in normal conjunctiva and failed filtering blebs. Mol Vis (2008) 1.01
Transcriptional regulation of the cannabinoid receptor type 1 gene in T cells by cannabinoids. J Leukoc Biol (2006) 1.01
Histologic findings in pigment dispersion syndrome and pigmentary glaucoma. J Glaucoma (2006) 1.00
Structure analysis of bone morphogenetic protein-2 type I receptor complexes reveals a mechanism of receptor inactivation in juvenile polyposis syndrome. J Biol Chem (2007) 1.00
Evaluation of soluble junctional adhesion molecule-A as a biomarker of human brain endothelial barrier breakdown. PLoS One (2010) 1.00
Oligomeric interactions of TGF-β and BMP receptors. FEBS Lett (2012) 0.99
Adenoviral BMP-2 gene transfer in mesenchymal stem cells: in vitro and in vivo bone formation on biodegradable polymer scaffolds. Biochem Biophys Res Commun (2002) 0.99
BMP2 and mechanical loading cooperatively regulate immediate early signalling events in the BMP pathway. BMC Biol (2012) 0.99
miR-181a promotes osteoblastic differentiation through repression of TGF-β signaling molecules. Int J Biochem Cell Biol (2012) 0.99
Are there filtering blebs after canaloplasty? J Glaucoma (2012) 0.99
Elasticity-dependent modulation of TGF-β responses in human trabecular meshwork cells. Invest Ophthalmol Vis Sci (2011) 0.98
Functional epitope of common gamma chain for interleukin-4 binding. Eur J Biochem (2002) 0.98
Long-term results of surgery in childhood glaucoma. Graefes Arch Clin Exp Ophthalmol (2007) 0.98
Polyethylenimine-PEG coated albumin nanoparticles for BMP-2 delivery. Biomaterials (2009) 0.97
Novel crosstalk to BMP signalling: cGMP-dependent kinase I modulates BMP receptor and Smad activity. EMBO J (2009) 0.97
In vitro osteogenic response of rat bone marrow cells to bFGF and BMP-2 treatments. Clin Orthop Relat Res (2006) 0.97
Constitutively active ALK2 receptor mutants require type II receptor cooperation. Mol Cell Biol (2013) 0.96
Human osteoprogenitor bone formation using encapsulated bone morphogenetic protein 2 in porous polymer scaffolds. Tissue Eng (2004) 0.96
Genome-wide significant association of ANKRD55 rs6859219 and multiple sclerosis risk. J Med Genet (2013) 0.96
A modular interface of IL-4 allows for scalable affinity without affecting specificity for the IL-4 receptor. BMC Biol (2006) 0.95
MANBA, CXCR5, SOX8, RPS6KB1 and ZBTB46 are genetic risk loci for multiple sclerosis. Brain (2013) 0.94
B cell-specific deficiency for Smad2 in vivo leads to defects in TGF-beta-directed IgA switching and changes in B cell fate. J Immunol (2006) 0.93
Human IL-21 and IL-4 bind to partially overlapping epitopes of common gamma-chain. Biochem Biophys Res Commun (2003) 0.93
Nerve growth factor mediates activation of the Smad pathway in PC12 cells. Eur J Biochem (2004) 0.93
Natalizumab exerts direct signaling capacity and supports a pro-inflammatory phenotype in some patients with multiple sclerosis. PLoS One (2012) 0.93
Large-area versus small-area application of mitomycin C during trabeculectomy. Eur J Ophthalmol (2013) 0.93
Effect of the distribution and clustering of the type I A BMP receptor (ALK3) with the type II BMP receptor on the activation of signalling pathways. J Cell Sci (2003) 0.91
BMPs are mediators in tissue crosstalk of the regenerating musculoskeletal system. Cell Tissue Res (2012) 0.91
Binding between Crossveinless-2 and Chordin von Willebrand factor type C domains promotes BMP signaling by blocking Chordin activity. PLoS One (2010) 0.91
Differential expression of angioregulatory factors in normal and CNV-derived human retinal pigment epithelium. Graefes Arch Clin Exp Ophthalmol (2004) 0.90
The solution structure of BMPR-IA reveals a local disorder-to-order transition upon BMP-2 binding. Biochemistry (2008) 0.90
Quantitative analysis of TGFBR2 mutations in Marfan-syndrome-related disorders suggests a correlation between phenotypic severity and Smad signaling activity. J Cell Sci (2010) 0.89
The PLPp-specific T-cell population promoted by pertussis toxin is characterized by high frequencies of IL-17-producing cells. Cytokine (2007) 0.89
Non-invasive assessment of retinal alterations in mouse models of infantile and juvenile neuronal ceroid lipofuscinosis by spectral domain optical coherence tomography. Acta Neuropathol Commun (2014) 0.88
PP2A regulates BMP signalling by interacting with BMP receptor complexes and by dephosphorylating both the C-terminus and the linker region of Smad1. J Cell Sci (2009) 0.88
The peptides ADNF-9 and NAP increase survival and neurite outgrowth of rat retinal ganglion cells in vitro. Invest Ophthalmol Vis Sci (2005) 0.88
In vivo confocal microscopy of failing and functioning filtering blebs: Results and clinical correlations. J Glaucoma (2006) 0.88
Nanoscale control of surface immobilized BMP-2: toward a quantitative assessment of BMP-mediated signaling events. Nano Lett (2015) 0.87
Long-term results of cataract surgery combined with trabeculotomy. Graefes Arch Clin Exp Ophthalmol (2002) 0.87
Changes in macular thickness and depth of anterior chamber in patients after filtration surgery. Graefes Arch Clin Exp Ophthalmol (2003) 0.87
Formation of stable homomeric and transient heteromeric bone morphogenetic protein (BMP) receptor complexes regulates Smad protein signaling. J Biol Chem (2011) 0.87