Published in Dev Dyn on July 01, 2006
Snail and Slug promote epithelial-mesenchymal transition through beta-catenin-T-cell factor-4-dependent expression of transforming growth factor-beta3. Mol Biol Cell (2008) 2.78
Palatogenesis: morphogenetic and molecular mechanisms of secondary palate development. Development (2012) 2.01
TGFbeta3 inhibits E-cadherin gene expression in palate medial-edge epithelial cells through a Smad2-Smad4-LEF1 transcription complex. J Cell Sci (2007) 1.73
Palate morphogenesis: current understanding and future directions. Birth Defects Res C Embryo Today (2010) 0.94
siRNA as a tool for investigating organogenesis: The pitfalls and the promises. Organogenesis (2008) 0.84
MiR-200b is involved in Tgf-β signaling to regulate mammalian palate development. Histochem Cell Biol (2011) 0.82
Matrix metalloproteinase-25 has a functional role in mouse secondary palate development and is a downstream target of TGF-β3. BMC Dev Biol (2010) 0.81
Type III transforming growth factor beta receptor regulates vascular and osteoblast development during palatogenesis. Dev Dyn (2014) 0.80
Functional role of TGF-β receptors during palatal fusion in vitro. Arch Oral Biol (2014) 0.76
Induction of colonic regulatory T cells by indigenous Clostridium species. Science (2010) 16.71
T cell receptor-proximal signals are sustained in peripheral microclusters and terminated in the central supramolecular activation cluster. Immunity (2006) 6.93
A cAMP-response element binding protein-induced microRNA regulates neuronal morphogenesis. Proc Natl Acad Sci U S A (2005) 6.61
Newly generated T cell receptor microclusters initiate and sustain T cell activation by recruitment of Zap70 and SLP-76. Nat Immunol (2005) 6.48
Mincle is an ITAM-coupled activating receptor that senses damaged cells. Nat Immunol (2008) 4.66
Thymic selection determines gammadelta T cell effector fate: antigen-naive cells make interleukin-17 and antigen-experienced cells make interferon gamma. Immunity (2008) 4.21
The adaptor protein CARD9 is essential for the activation of myeloid cells through ITAM-associated and Toll-like receptors. Nat Immunol (2007) 4.12
Dectin-2 recognition of alpha-mannans and induction of Th17 cell differentiation is essential for host defense against Candida albicans. Immunity (2010) 3.66
Clinical proteomics: A need to define the field and to begin to set adequate standards. Proteomics Clin Appl (2007) 2.84
Conditional inactivation of Tgfbr2 in cranial neural crest causes cleft palate and calvaria defects. Development (2003) 2.78
miRNA-mediated deadenylation is orchestrated by GW182 through two conserved motifs that interact with CCR4-NOT. Nat Struct Mol Biol (2011) 2.61
Programmed cell death 1 forms negative costimulatory microclusters that directly inhibit T cell receptor signaling by recruiting phosphatase SHP2. J Exp Med (2012) 2.58
Human Bub1 defines the persistent cohesion site along the mitotic chromosome by affecting Shugoshin localization. Curr Biol (2005) 2.53
Spatiotemporal regulation of T cell costimulation by TCR-CD28 microclusters and protein kinase C theta translocation. Immunity (2008) 2.42
The Plk1 target Kizuna stabilizes mitotic centrosomes to ensure spindle bipolarity. Nat Cell Biol (2006) 2.37
The human proteome project: current state and future direction. Mol Cell Proteomics (2011) 2.34
Effects of resin hydrophilicity on water sorption and changes in modulus of elasticity. Biomaterials (2005) 2.32
C-type lectin Mincle is an activating receptor for pathogenic fungus, Malassezia. Proc Natl Acad Sci U S A (2009) 2.25
Role for hydrogen peroxide in flow-induced dilation of human coronary arterioles. Circ Res (2003) 2.09
Multicentric peripheral ossifying fibroma. J Oral Sci (2006) 2.06
Diabetes mellitus impairs vasodilation to hypoxia in human coronary arterioles: reduced activity of ATP-sensitive potassium channels. Circ Res (2003) 2.01
Association of HTRA1 mutations and familial ischemic cerebral small-vessel disease. N Engl J Med (2009) 1.96
Fc{epsilon}RI-mediated mast cell degranulation requires calcium-independent microtubule-dependent translocation of granules to the plasma membrane. J Cell Biol (2005) 1.91
Oral bisphosphonate use and the prevalence of osteonecrosis of the jaw: an institutional inquiry. J Am Dent Assoc (2009) 1.84
The intermediate-conductance calcium-activated potassium channel KCa3.1 contributes to atherogenesis in mice and humans. J Clin Invest (2008) 1.82
Mechanistic basis of pre-T cell receptor-mediated autonomous signaling critical for thymocyte development. Nat Immunol (2005) 1.75
Dynein-driven transport of T cell receptor microclusters regulates immune synapse formation and T cell activation. Immunity (2011) 1.75
Construction of an open-access database that integrates cross-reference information from the transcriptome and proteome of immune cells. Bioinformatics (2007) 1.73
Immunoglobulin-free light chains elicit immediate hypersensitivity-like responses. Nat Med (2002) 1.73
Accidental exposures to blood and body fluid in the operation room and the issue of underreporting. Am J Infect Control (2009) 1.66
Interaction of CagA with Crk plays an important role in Helicobacter pylori-induced loss of gastric epithelial cell adhesion. J Exp Med (2005) 1.66
Activation of natural killer cells and dendritic cells upon recognition of a novel CD99-like ligand by paired immunoglobulin-like type 2 receptor. J Exp Med (2004) 1.64
BANK regulates BCR-induced calcium mobilization by promoting tyrosine phosphorylation of IP(3) receptor. EMBO J (2002) 1.64
The role of antigenic peptide in CD4+ T helper phenotype development in a T cell receptor transgenic model. Int Immunol (2004) 1.63
Cutting edge: TLR2 directly triggers Th1 effector functions. J Immunol (2007) 1.61
Recommendations for biomarker identification and qualification in clinical proteomics. Sci Transl Med (2010) 1.59
Sustained activation of N-WASP through phosphorylation is essential for neurite extension. Dev Cell (2002) 1.58
CRTAM confers late-stage activation of CD8+ T cells to regulate retention within lymph node. J Immunol (2009) 1.57
Lithium protection against glutamate excitotoxicity in rat cerebral cortical neurons: involvement of NMDA receptor inhibition possibly by decreasing NR2B tyrosine phosphorylation. J Neurochem (2002) 1.55
DNA polymerase theta contributes to the generation of C/G mutations during somatic hypermutation of Ig genes. Proc Natl Acad Sci U S A (2005) 1.53
State of the human proteome in 2013 as viewed through PeptideAtlas: comparing the kidney, urine, and plasma proteomes for the biology- and disease-driven Human Proteome Project. J Proteome Res (2013) 1.52
CD25(+)CD4(+) regulatory T cells exert in vitro suppressive activity independent of CTLA-4. Int Immunol (2005) 1.50
Arf induces p53-dependent and -independent antiproliferative genes. Cancer Res (2003) 1.49
Differential trafficking of Src, Lyn, Yes and Fyn is specified by the state of palmitoylation in the SH4 domain. J Cell Sci (2009) 1.49
Therapeutic effect of local administration of low-dose simvastatin-conjugated gelatin hydrogel for fracture healing. J Bone Miner Res (2012) 1.48
p250GAP, a novel brain-enriched GTPase-activating protein for Rho family GTPases, is involved in the N-methyl-d-aspartate receptor signaling. Mol Biol Cell (2003) 1.48
Disruption of aquaporin-11 produces polycystic kidneys following vacuolization of the proximal tubule. Mol Cell Biol (2005) 1.48
Down-regulation of basophil function by human CD200 and human herpesvirus-8 CD200. J Immunol (2005) 1.47
Upregulation of nestin, vimentin, and desmin in rat podocytes in response to injury. Virchows Arch (2006) 1.46
Effective suppression of hippocampal seizures in rats by direct hippocampal cooling with a Peltier chip. J Neurosurg (2008) 1.45
Involvement of gangliosides in the process of Cbp/PAG phosphorylation by Lyn in developing cerebellar growth cones. J Neurochem (2013) 1.44
Cutting edge: negative regulation of immune synapse formation by anchoring lipid raft to cytoskeleton through Cbp-EBP50-ERM assembly. J Immunol (2002) 1.44
Oligo-astheno-teratozoospermia in mice lacking Cnot7, a regulator of retinoid X receptor beta. Nat Genet (2004) 1.40
Diversity of translation start sites may define increased complexity of the human short ORFeome. Mol Cell Proteomics (2007) 1.39
Relationship between left coronary artery bifurcation angle and restenosis after stenting of the proximal left anterior descending artery. Coron Artery Dis (2016) 1.39
Relation between VE/VCO2 slope and maximum phonation time in chronic heart failure patients. Medicine (Baltimore) (2014) 1.39
Complement activation selectively potentiates the pathogenicity of the IgG2b and IgG3 isotypes of a high affinity anti-erythrocyte autoantibody. J Exp Med (2002) 1.39
Phosphorylation of three regulatory serines of Tob by Erk1 and Erk2 is required for Ras-mediated cell proliferation and transformation. Genes Dev (2002) 1.36
CARD9 versus CARMA1 in innate and adaptive immunity. Trends Immunol (2009) 1.36
The molecular adapter Carma1 controls entry of IkappaB kinase into the central immune synapse. J Exp Med (2004) 1.35
ALK receptor tyrosine kinase promotes cell growth and neurite outgrowth. J Cell Sci (2004) 1.34
In-frame dystrophin following exon 51-skipping improves muscle pathology and function in the exon 52-deficient mdx mouse. Mol Ther (2010) 1.33
Crystal structure of the human CNOT6L nuclease domain reveals strict poly(A) substrate specificity. EMBO J (2010) 1.33
Bodywide skipping of exons 45-55 in dystrophic mdx52 mice by systemic antisense delivery. Proc Natl Acad Sci U S A (2012) 1.32
NR2B tyrosine phosphorylation modulates fear learning as well as amygdaloid synaptic plasticity. EMBO J (2006) 1.32
Dynamic regulation of T-cell costimulation through TCR-CD28 microclusters. Immunol Rev (2009) 1.32
Identification of microbial biofilms in osteonecrosis of the jaws secondary to bisphosphonate therapy. J Oral Maxillofac Surg (2008) 1.32
Fyn kinase-mediated phosphorylation of NMDA receptor NR2B subunit at Tyr1472 is essential for maintenance of neuropathic pain. Eur J Neurosci (2005) 1.32
Aβ secretion and plaque formation depend on autophagy. Cell Rep (2013) 1.32
Mice lacking a transcriptional corepressor Tob are predisposed to cancer. Genes Dev (2003) 1.31
Role of Dok-1 and Dok-2 in myeloid homeostasis and suppression of leukemia. J Exp Med (2004) 1.31
LATS2-Ajuba complex regulates gamma-tubulin recruitment to centrosomes and spindle organization during mitosis. FEBS Lett (2006) 1.30
Kid-mediated chromosome compaction ensures proper nuclear envelope formation. Cell (2008) 1.30
A motif in the V3 domain of the kinase PKC-θ determines its localization in the immunological synapse and functions in T cells via association with CD28. Nat Immunol (2011) 1.30
Depletion of mammalian CCR4b deadenylase triggers elevation of the p27Kip1 mRNA level and impairs cell growth. Mol Cell Biol (2007) 1.29
Microbial biofilms in osteomyelitis of the jaw and osteonecrosis of the jaw secondary to bisphosphonate therapy. J Am Dent Assoc (2009) 1.28
Interaction of anti-proliferative protein Tob with poly(A)-binding protein and inducible poly(A)-binding protein: implication of Tob in translational control. Genes Cells (2005) 1.28
CD151 enhances cell motility and metastasis of cancer cells in the presence of focal adhesion kinase. Int J Cancer (2002) 1.26
The immunological synapse, TCR microclusters, and T cell activation. Curr Top Microbiol Immunol (2010) 1.26
TRAF6-deficient mice display hypohidrotic ectodermal dysplasia. Proc Natl Acad Sci U S A (2002) 1.25
NFAM1, an immunoreceptor tyrosine-based activation motif-bearing molecule that regulates B cell development and signaling. Proc Natl Acad Sci U S A (2004) 1.25
Spatiotemporal basis of CTLA-4 costimulatory molecule-mediated negative regulation of T cell activation. Immunity (2010) 1.24
Cell type-specific regulation of ITAM-mediated NF-kappaB activation by the adaptors, CARMA1 and CARD9. J Immunol (2008) 1.23
GPVI levels in platelets: relationship to platelet function at high shear. Blood (2003) 1.23
The chromokinesin Kid is required for maintenance of proper metaphase spindle size. Mol Biol Cell (2005) 1.23
Toward deciphering proteomes of formalin-fixed paraffin-embedded (FFPE) tissues. Proteomics (2012) 1.23
The actin cloud induced by LFA-1-mediated outside-in signals lowers the threshold for T-cell activation. Blood (2006) 1.23
Membrane-bound human SCF/KL promotes in vivo human hematopoietic engraftment and myeloid differentiation. Blood (2012) 1.23
Expression of the cartilage derived anti-angiogenic factor chondromodulin-I decreases in the early stage of experimental osteoarthritis. J Rheumatol (2003) 1.23
Defective function of GABA-containing synaptic vesicles in mice lacking the AP-3B clathrin adaptor. J Cell Biol (2004) 1.22
Tyrosine dephosphorylation and ethanol inhibition of N-Methyl-D-aspartate receptor function. J Biol Chem (2003) 1.22
Mechanism of vasodilation to adenosine in coronary arterioles from patients with heart disease. Am J Physiol Heart Circ Physiol (2005) 1.22
Activation of extracellular signal-regulated kinase by ultraviolet is mediated through Src-dependent epidermal growth factor receptor phosphorylation. Its implication in an anti-apoptotic function. J Biol Chem (2001) 1.21
A lysosomal protein negatively regulates surface T cell antigen receptor expression by promoting CD3zeta-chain degradation. Immunity (2008) 1.20
Celiac disease and recurrent aphthous stomatitis: a report and review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod (2002) 1.20
Regulation of actin cytoskeleton by mDab1 through N-WASP and ubiquitination of mDab1. Biochem J (2004) 1.20
Standard guidelines for the chromosome-centric human proteome project. J Proteome Res (2012) 1.20
Role of the kinesin-2 family protein, KIF3, during mitosis. J Biol Chem (2005) 1.18
Negative control of basophil expansion by IRF-2 critical for the regulation of Th1/Th2 balance. Blood (2005) 1.18
Identification of distinct ligands for the C-type lectin receptors Mincle and Dectin-2 in the pathogenic fungus Malassezia. Cell Host Microbe (2013) 1.17