Published in J Immunol on May 01, 2006
Mitochondrial dysfunction increases allergic airway inflammation. J Immunol (2009) 1.46
Redox control of asthma: molecular mechanisms and therapeutic opportunities. Antioxid Redox Signal (2010) 1.43
Alterations of the arginine metabolome in asthma. Am J Respir Crit Care Med (2008) 1.40
Nuclear factor kappaB, airway epithelium, and asthma: avenues for redox control. Proc Am Thorac Soc (2009) 1.31
Modulation of glutaredoxin-1 expression in a mouse model of allergic airway disease. Am J Respir Cell Mol Biol (2006) 1.25
Oxidative risk for atherothrombotic cardiovascular disease. Free Radic Biol Med (2009) 1.24
Respiratory syncytial virus induces oxidative stress by modulating antioxidant enzymes. Am J Respir Cell Mol Biol (2009) 1.17
Inhibition of arginase activity enhances inflammation in mice with allergic airway disease, in association with increases in protein S-nitrosylation and tyrosine nitration. J Immunol (2008) 1.13
Lung imaging in asthmatic patients: the picture is clearer. J Allergy Clin Immunol (2011) 1.10
An airway epithelial iNOS-DUOX2-thyroid peroxidase metabolome drives Th1/Th2 nitrative stress in human severe asthma. Mucosal Immunol (2014) 1.09
Inhibition of lung fluid clearance and epithelial Na+ channels by chlorine, hypochlorous acid, and chloramines. J Biol Chem (2010) 1.09
Levels of nitric oxide oxidation products are increased in the epithelial lining fluid of children with persistent asthma. J Allergy Clin Immunol (2009) 1.08
Viral-mediated inhibition of antioxidant enzymes contributes to the pathogenesis of severe respiratory syncytial virus bronchiolitis. Am J Respir Crit Care Med (2011) 1.02
Protein nitration in placenta - functional significance. Placenta (2008) 1.02
Glutathione redox control of asthma: from molecular mechanisms to therapeutic opportunities. Antioxid Redox Signal (2012) 1.01
Ozone enhancement of lower airway allergic inflammation is prevented by gamma-tocopherol. Free Radic Biol Med (2007) 1.00
Airway biomarkers of the oxidant burden in asthma and chronic obstructive pulmonary disease: current and future perspectives. Int J Chron Obstruct Pulmon Dis (2008) 1.00
Detrimental effects of environmental tobacco smoke in relation to asthma severity. PLoS One (2011) 0.97
Nitric oxide in adaptation to altitude. Free Radic Biol Med (2012) 0.96
Assessment of association of exposure to polycyclic aromatic hydrocarbons with bronchial asthma and oxidative stress in children: A case control study. Indian J Occup Environ Med (2009) 0.90
Functional variants in the catalase and myeloperoxidase genes, ambient air pollution, and respiratory-related school absences: an example of epistasis in gene-environment interactions. Am J Epidemiol (2009) 0.90
Nitric oxide metabolism in asthma pathophysiology. Biochim Biophys Acta (2011) 0.89
The impact of nitration on the structure and immunogenicity of the major birch pollen allergen Bet v 1.0101. PLoS One (2014) 0.89
Post-translational tyrosine nitration of eosinophil granule toxins mediated by eosinophil peroxidase. J Biol Chem (2008) 0.88
Genomics and proteomics of lung disease: conference summary. Am J Physiol Lung Cell Mol Physiol (2007) 0.88
Disulfide bond as a switch for copper-zinc superoxide dismutase activity in asthma. Antioxid Redox Signal (2012) 0.86
The role of catalase in pulmonary fibrosis. Respir Res (2010) 0.85
The impact of surfactant protein-A on ozone-induced changes in the mouse bronchoalveolar lavage proteome. Proteome Sci (2009) 0.85
Reactive metabolites and antioxidant gene polymorphisms in Type 2 diabetes mellitus. Redox Biol (2013) 0.84
Severe vitamin E deficiency modulates airway allergic inflammatory responses in the murine asthma model. Free Radic Res (2008) 0.84
Proteinase activated receptor-2-mediated dual oxidase-2 up-regulation is involved in enhanced airway reactivity and inflammation in a mouse model of allergic asthma. Immunology (2015) 0.82
Increased mitochondrial arginine metabolism supports bioenergetics in asthma. J Clin Invest (2016) 0.81
Catalase overexpression fails to attenuate allergic airways disease in the mouse. J Immunol (2007) 0.80
Biomarkers in asthma: a real hope to better manage asthma. Clin Chest Med (2012) 0.80
Glucose-mediated tyrosine nitration in adipocytes: targets and consequences. Free Radic Biol Med (2008) 0.79
Oxidative Stress and Therapeutic Development in Lung Diseases. J Pulm Respir Med (2014) 0.79
Reactive metabolites and antioxidant gene polymorphisms in type 2 diabetes mellitus. Indian J Hum Genet (2014) 0.79
Phosphorylation inactivation of endothelial nitric oxide synthesis in pulmonary arterial hypertension. Am J Physiol Lung Cell Mol Physiol (2016) 0.78
Overexpression of Catalase Diminishes Oxidative Cysteine Modifications of Cardiac Proteins. PLoS One (2015) 0.78
Modulation of Asthma Pathogenesis by Nitric Oxide Pathways and Therapeutic Opportunities. Drug Discov Today Dis Mech (2012) 0.78
Severe Asthma in Children: Lessons Learned and Future Directions. J Allergy Clin Immunol Pract (2016) 0.77
Novel insights in mammalian catalase heme maturation: EFFect of NO and thioredoxin-1. Free Radic Biol Med (2015) 0.77
Endothelin-1 stimulates catalase activity through the PKCδ-mediated phosphorylation of serine 167. Free Radic Biol Med (2013) 0.77
New Insights in Oxidant Biology in Asthma. Ann Am Thorac Soc (2016) 0.76
The effect of hydro-ethanolic extract of Curcuma longa rhizome and curcumin on total and differential WBC and serum oxidant, antioxidant biomarkers in rat model of asthma. Iran J Basic Med Sci (2017) 0.75
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease. Nature (2011) 13.53
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet (2011) 13.25
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis. Nat Med (2013) 9.44
Intestinal microbial metabolism of phosphatidylcholine and cardiovascular risk. N Engl J Med (2013) 8.21
Large-scale association analysis identifies new risk loci for coronary artery disease. Nat Genet (2012) 7.59
Identification of asthma phenotypes using cluster analysis in the Severe Asthma Research Program. Am J Respir Crit Care Med (2009) 7.17
Characterization of the severe asthma phenotype by the National Heart, Lung, and Blood Institute's Severe Asthma Research Program. J Allergy Clin Immunol (2007) 6.33
Dysregulated arginine metabolism, hemolysis-associated pulmonary hypertension, and mortality in sickle cell disease. JAMA (2005) 6.14
Prognostic value of myeloperoxidase in patients with chest pain. N Engl J Med (2003) 5.89
An official ATS clinical practice guideline: interpretation of exhaled nitric oxide levels (FENO) for clinical applications. Am J Respir Crit Care Med (2011) 5.53
The adaptor Act1 is required for interleukin 17-dependent signaling associated with autoimmune and inflammatory disease. Nat Immunol (2007) 5.33
Protein carbamylation links inflammation, smoking, uremia and atherogenesis. Nat Med (2007) 4.30
Platelet CD36 links hyperlipidemia, oxidant stress and a prothrombotic phenotype. Nat Med (2007) 4.11
Common variants in KCNN3 are associated with lone atrial fibrillation. Nat Genet (2010) 3.97
Relationship of paraoxonase 1 (PON1) gene polymorphisms and functional activity with systemic oxidative stress and cardiovascular risk. JAMA (2008) 3.64
Apolipoprotein A-I is a selective target for myeloperoxidase-catalyzed oxidation and functional impairment in subjects with cardiovascular disease. J Clin Invest (2004) 3.63
Hyperproliferative apoptosis-resistant endothelial cells in idiopathic pulmonary arterial hypertension. Am J Physiol Lung Cell Mol Physiol (2007) 3.28
Statins, high-density lipoprotein cholesterol, and regression of coronary atherosclerosis. JAMA (2007) 3.25
A novel family of atherogenic oxidized phospholipids promotes macrophage foam cell formation via the scavenger receptor CD36 and is enriched in atherosclerotic lesions. J Biol Chem (2002) 3.17
New gene functions in megakaryopoiesis and platelet formation. Nature (2011) 3.14
Noncanonical function of glutamyl-prolyl-tRNA synthetase: gene-specific silencing of translation. Cell (2004) 3.12
Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project. PLoS Genet (2011) 3.07
Paradoxical association of enhanced cholesterol efflux with increased incident cardiovascular risks. Arterioscler Thromb Vasc Biol (2013) 3.07
A CD36-dependent signaling cascade is necessary for macrophage foam cell formation. Cell Metab (2006) 3.06
Trimethylamine-N-oxide, a metabolite associated with atherosclerosis, exhibits complex genetic and dietary regulation. Cell Metab (2013) 3.01
Detection of lung cancer by sensor array analyses of exhaled breath. Am J Respir Crit Care Med (2005) 2.94
Identification of a novel family of oxidized phospholipids that serve as ligands for the macrophage scavenger receptor CD36. J Biol Chem (2002) 2.94
Lung function in adults with stable but severe asthma: air trapping and incomplete reversal of obstruction with bronchodilation. J Appl Physiol (1985) (2007) 2.83
Serum myeloperoxidase levels independently predict endothelial dysfunction in humans. Circulation (2004) 2.79
Myeloperoxidase and cardiovascular disease. Arterioscler Thromb Vasc Biol (2005) 2.77
Seventy-five genetic loci influencing the human red blood cell. Nature (2012) 2.77
An endothelial apelin-FGF link mediated by miR-424 and miR-503 is disrupted in pulmonary arterial hypertension. Nat Med (2012) 2.59
Oxidized phosphatidylserine-CD36 interactions play an essential role in macrophage-dependent phagocytosis of apoptotic cells. J Exp Med (2006) 2.51
The refined structure of nascent HDL reveals a key functional domain for particle maturation and dysfunction. Nat Struct Mol Biol (2007) 2.47
Alterations of cellular bioenergetics in pulmonary artery endothelial cells. Proc Natl Acad Sci U S A (2007) 2.44
Increased arginase II and decreased NO synthesis in endothelial cells of patients with pulmonary arterial hypertension. FASEB J (2004) 2.37
Diminished global arginine bioavailability and increased arginine catabolism as metabolic profile of increased cardiovascular risk. J Am Coll Cardiol (2009) 2.35
The lipid whisker model of the structure of oxidized cell membranes. J Biol Chem (2007) 2.31
Features of severe asthma in school-age children: Atopy and increased exhaled nitric oxide. J Allergy Clin Immunol (2006) 2.30
Effect of plasma uric acid on antioxidant capacity, oxidative stress, and insulin sensitivity in obese subjects. Diabetes (2013) 2.25
Serum myeloperoxidase levels are associated with the future risk of coronary artery disease in apparently healthy individuals: the EPIC-Norfolk Prospective Population Study. J Am Coll Cardiol (2007) 2.22
Serum uric acid is an independent predictor of all-cause mortality in patients at high risk of cardiovascular disease: a preventive cardiology information system (PreCIS) database cohort study. Arthritis Rheum (2008) 2.19
Association of nitrotyrosine levels with cardiovascular disease and modulation by statin therapy. JAMA (2003) 2.16
Somatic chromosome abnormalities in the lungs of patients with pulmonary arterial hypertension. Am J Respir Crit Care Med (2010) 2.09
Prognostic value of choline and betaine depends on intestinal microbiota-generated metabolite trimethylamine-N-oxide. Eur Heart J (2014) 2.08
Hypoxia-inducible factors in human pulmonary arterial hypertension: a link to the intrinsic myeloid abnormalities. Blood (2011) 2.08
Early effect of tidal volume on lung injury biomarkers in surgical patients with healthy lungs. Anesthesiology (2014) 2.06
Act1, a U-box E3 ubiquitin ligase for IL-17 signaling. Sci Signal (2009) 2.05
Myeloperoxidase functions as a major enzymatic catalyst for initiation of lipid peroxidation at sites of inflammation. J Biol Chem (2002) 2.02
Oxidative and nitrosative events in asthma. Free Radic Biol Med (2003) 1.97
Direct and differential suppression of myeloid-derived suppressor cell subsets by sunitinib is compartmentally constrained. Cancer Res (2010) 1.92
p53 is a suppressor of inflammatory response in mice. FASEB J (2005) 1.91
Circulating angiogenic precursors in idiopathic pulmonary arterial hypertension. Am J Pathol (2008) 1.90
Asthma outcomes: biomarkers. J Allergy Clin Immunol (2012) 1.88
Concurrent evaluation of novel cardiac biomarkers in acute coronary syndrome: myeloperoxidase and soluble CD40 ligand and the risk of recurrent ischaemic events in TACTICS-TIMI 18. Eur Heart J (2008) 1.88
Association between four SNPs on chromosome 9p21 and myocardial infarction is replicated in an Italian population. J Hum Genet (2007) 1.87
Relationship between cardiovascular risk factors and atherosclerotic disease burden measured by intravascular ultrasound. J Am Coll Cardiol (2006) 1.87
Differential effects of arginine methylation on diastolic dysfunction and disease progression in patients with chronic systolic heart failure. Eur Heart J (2008) 1.85
An association between L-arginine/asymmetric dimethyl arginine balance, obesity, and the age of asthma onset phenotype. Am J Respir Crit Care Med (2012) 1.85
Metabolic profiling of arginine and nitric oxide pathways predicts hemodynamic abnormalities and mortality in patients with cardiogenic shock after acute myocardial infarction. Circulation (2007) 1.85
Coronary artery calcification and changes in atheroma burden in response to established medical therapies. J Am Coll Cardiol (2006) 1.84
Localization of nitration and chlorination sites on apolipoprotein A-I catalyzed by myeloperoxidase in human atheroma and associated oxidative impairment in ABCA1-dependent cholesterol efflux from macrophages. J Biol Chem (2004) 1.80
Hypoxia inducible-factor1alpha regulates the metabolic shift of pulmonary hypertensive endothelial cells. Am J Pathol (2010) 1.79
Severe asthma: lessons learned from the National Heart, Lung, and Blood Institute Severe Asthma Research Program. Am J Respir Crit Care Med (2011) 1.76
Plasma myeloperoxidase predicts incident cardiovascular risks in stable patients undergoing medical management for coronary artery disease. Clin Chem (2010) 1.74
Correlation of systemic superoxide dismutase deficiency to airflow obstruction in asthma. Am J Respir Crit Care Med (2005) 1.72
DAPK-ZIPK-L13a axis constitutes a negative-feedback module regulating inflammatory gene expression. Mol Cell (2008) 1.70
High-density lipoprotein function, dysfunction, and reverse cholesterol transport. Arterioscler Thromb Vasc Biol (2012) 1.70
Gene expression in relation to exhaled nitric oxide identifies novel asthma phenotypes with unique biomolecular pathways. Am J Respir Crit Care Med (2014) 1.69
Levels of soluble endothelium-derived adhesion molecules in patients with sickle cell disease are associated with pulmonary hypertension, organ dysfunction, and mortality. Br J Haematol (2005) 1.69
Statins promote potent systemic antioxidant effects through specific inflammatory pathways. Circulation (2003) 1.69
Pulmonary hypertension associated with advanced systolic heart failure: dysregulated arginine metabolism and importance of compensatory dimethylarginine dimethylaminohydrolase-1. J Am Coll Cardiol (2012) 1.69
Use of exhaled nitric oxide measurement to identify a reactive, at-risk phenotype among patients with asthma. Am J Respir Crit Care Med (2010) 1.68