Published in Ann N Y Acad Sci on January 01, 1991
Targeting expression of keratinocyte growth factor to keratinocytes elicits striking changes in epithelial differentiation in transgenic mice. EMBO J (1993) 1.70
Intratracheal instillation of keratinocyte growth factor decreases hyperoxia-induced mortality in rats. J Clin Invest (1995) 1.68
Antisense targeting of perlecan blocks tumor growth and angiogenesis in vivo. J Clin Invest (1998) 1.46
Alternative splicing in fibroblast growth factor receptor 2 is associated with induced epithelial-mesenchymal transition in rat bladder carcinoma cells. Mol Biol Cell (1994) 1.46
Pulmonary malformation in transgenic mice expressing human keratinocyte growth factor in the lung. Proc Natl Acad Sci U S A (1995) 1.16
Biomimetic delivery of keratinocyte growth factor upon cellular demand for accelerated wound healing in vitro and in vivo. Am J Pathol (2005) 1.05
Differential binding of fibroblast growth factor-2 and -7 to basement membrane heparan sulfate: comparison of normal and abnormal human tissues. Am J Pathol (1997) 1.05
Keratinocyte growth factor-induced motility of breast cancer cells. Clin Exp Metastasis (2000) 1.00
Keratinocyte growth factor ameliorates dextran sodium sulfate colitis in mice. Dig Dis Sci (1999) 0.90
Fibrinogen and fibrin based micro and nano scaffolds incorporated with drugs, proteins, cells and genes for therapeutic biomedical applications. Int J Nanomedicine (2013) 0.90
A role for the perlecan protein core in the activation of the keratinocyte growth factor receptor. Biochem J (2001) 0.89
Palifermin for oral mucositis in the high-dose chemotherapy and stem cell transplant setting: the Royal Adelaide Hospital Cancer Centre experience. Support Care Cancer (2006) 0.85
A 10-amino acid sequence of fibroblast growth factor 2 is sufficient for its mitogenic activity on neural progenitor cells. Proc Natl Acad Sci U S A (1997) 0.82
KGF-induced motility of breast cancer cells is dependent on Grb2 and Erk1,2. Clin Exp Metastasis (2004) 0.82
Keratinocyte growth factor is a bifunctional regulator of HPV16 DNA-immortalized cervical epithelial cells. J Cell Biol (1995) 0.81
Therapeutic potential of growth factors in pulmonary emphysematous condition. Lung (2012) 0.80
Controlled release of repifermin from polyelectrolyte complexes stimulates endothelial cell proliferation. J Pharm Sci (2009) 0.79
Lung interstitial cells during alveolarization. Korean J Pediatr (2010) 0.78
Regulated translation initiation controls stress-induced gene expression in mammalian cells. Mol Cell (2000) 17.44
Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase. Nature (1999) 16.97
A single ataxia telangiectasia gene with a product similar to PI-3 kinase. Science (1995) 15.20
Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1. Science (2000) 13.62
CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum. Genes Dev (1998) 11.86
Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response. Nat Cell Biol (2000) 11.62
Perk is essential for translational regulation and cell survival during the unfolded protein response. Mol Cell (2000) 11.09
Positional cloning of the Werner's syndrome gene. Science (1996) 10.98
The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway. Cell (1995) 9.82
Cloning of the gene coding for a shared human melanoma antigen recognized by autologous T cells infiltrating into tumor. Proc Natl Acad Sci U S A (1994) 8.92
Somatic CALR mutations in myeloproliferative neoplasms with nonmutated JAK2. N Engl J Med (2013) 8.89
Identification of the hepatocyte growth factor receptor as the c-met proto-oncogene product. Science (1991) 8.68
Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival. Mol Cell (2001) 8.60
Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha. J Cell Biol (2001) 7.82
DNA damage activates p53 through a phosphorylation-acetylation cascade. Genes Dev (1998) 7.78
Identification of a human melanoma antigen recognized by tumor-infiltrating lymphocytes associated with in vivo tumor rejection. Proc Natl Acad Sci U S A (1994) 6.93
Cloning of mammalian Ire1 reveals diversity in the ER stress responses. EMBO J (1998) 5.96
The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites. Genes Dev (2000) 5.72
Fusion of CHOP to a novel RNA-binding protein in human myxoid liposarcoma. Nature (1993) 5.69
Overexpression of the human EGF receptor confers an EGF-dependent transformed phenotype to NIH 3T3 cells. Cell (1987) 5.11
Purification and characterization of a newly identified growth factor specific for epithelial cells. Proc Natl Acad Sci U S A (1989) 5.10
Signals from the stressed endoplasmic reticulum induce C/EBP-homologous protein (CHOP/GADD153). Mol Cell Biol (1996) 5.01
Human KGF is FGF-related with properties of a paracrine effector of epithelial cell growth. Science (1989) 4.79
Determination of ligand-binding specificity by alternative splicing: two distinct growth factor receptors encoded by a single gene. Proc Natl Acad Sci U S A (1992) 4.50
PDGF induction of tyrosine phosphorylation of GTPase activating protein. Nature (1989) 4.36
Isolation and characterization of ERBB3, a third member of the ERBB/epidermal growth factor receptor family: evidence for overexpression in a subset of human mammary tumors. Proc Natl Acad Sci U S A (1989) 4.17
The gadd and MyD genes define a novel set of mammalian genes encoding acidic proteins that synergistically suppress cell growth. Mol Cell Biol (1994) 4.15
Isolation of a novel receptor cDNA establishes the existence of two PDGF receptor genes. Science (1989) 4.08
Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP Kinase. Science (1996) 4.03
Human ECT2 is an exchange factor for Rho GTPases, phosphorylated in G2/M phases, and involved in cytokinesis. J Cell Biol (1999) 3.77
Expression cDNA cloning of the KGF receptor by creation of a transforming autocrine loop. Science (1991) 3.69
Complex HLA-DR and -DQ interactions confer risk of narcolepsy-cataplexy in three ethnic groups. Am J Hum Genet (2001) 3.51
Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a. Genes Dev (1999) 3.41
CHOP (GADD153) and its oncogenic variant, TLS-CHOP, have opposing effects on the induction of G1/S arrest. Genes Dev (1994) 3.12
Stress-induced binding of the transcriptional factor CHOP to a novel DNA control element. Mol Cell Biol (1996) 2.98
Identification of novel stress-induced genes downstream of chop. EMBO J (1998) 2.93
A broad-spectrum human lung fibroblast-derived mitogen is a variant of hepatocyte growth factor. Proc Natl Acad Sci U S A (1991) 2.93
cAMP-GEFII is a direct target of cAMP in regulated exocytosis. Nat Cell Biol (2000) 2.83
Activation of RET as a dominant transforming gene by germline mutations of MEN2A and MEN2B. Science (1995) 2.83
Maternal undernutrition during the preimplantation period of rat development causes blastocyst abnormalities and programming of postnatal hypertension. Development (2000) 2.82
A subset of tumor-derived mutant forms of p53 down-regulate p63 and p73 through a direct interaction with the p53 core domain. Mol Cell Biol (2001) 2.69
Increased sensitivity to dextran sodium sulfate colitis in IRE1beta-deficient mice. J Clin Invest (2001) 2.67
Functional genomics of Escherichia coli in Japan. Res Microbiol (2000) 2.59
Inhibition of adipogenesis by the stress-induced protein CHOP (Gadd153). EMBO J (1995) 2.58
Frequency of choroidal abnormalities in neurofibromatosis type 1. Lancet (2000) 2.48
Development of a highly efficient expression cDNA cloning system: application to oncogene isolation. Proc Natl Acad Sci U S A (1991) 2.48
IRE1 and efferent signaling from the endoplasmic reticulum. J Cell Sci (2000) 2.46
Cloning of replication, incompatibility, and stability functions of R plasmid NR1. J Bacteriol (1980) 2.40
Purification and molecular cloning of a secreted, Frizzled-related antagonist of Wnt action. Proc Natl Acad Sci U S A (1997) 2.36
TLS (FUS) binds RNA in vivo and engages in nucleo-cytoplasmic shuttling. J Cell Sci (1997) 2.35
Oncogene ect2 is related to regulators of small GTP-binding proteins. Nature (1993) 2.34
Mapping of the resistance genes of the R plasmid NR1. Mol Gen Genet (1978) 2.32
Akt participation in the Wnt signaling pathway through Dishevelled. J Biol Chem (2001) 2.31
A novel effector domain from the RNA-binding protein TLS or EWS is required for oncogenic transformation by CHOP. Genes Dev (1994) 2.29
Signal transduction through the EGF receptor transfected in IL-3-dependent hematopoietic cells. Science (1988) 2.29
Conformational disease. Nat Cell Biol (2000) 2.29
Secreted frizzled-related protein-1 binds directly to Wingless and is a biphasic modulator of Wnt signaling. J Biol Chem (2000) 2.24
Disruption of the Bcl6 gene results in an impaired germinal center formation. J Exp Med (1997) 2.17
Critical role of cAMP-GEFII--Rim2 complex in incretin-potentiated insulin secretion. J Biol Chem (2001) 2.14
The nucleotide sequence of the uvrD gene of E. coli. Nucleic Acids Res (1984) 2.14
Comparison of haemodynamic responses to tracheal intubation using the Airway Scope(®) and Macintosh laryngoscope in normotensive and hypertensive patients. Anaesthesia (2011) 2.13
Isolation and biochemical characterization of the human Dkk-1 homologue, a novel inhibitor of mammalian Wnt signaling. J Biol Chem (1999) 2.12
Bacteriophage lambda carrying the Escherichia coli chromosomal region of the replication origin. Proc Natl Acad Sci U S A (1978) 2.11
C/ATF, a member of the activating transcription factor family of DNA-binding proteins, dimerizes with CAAT/enhancer-binding proteins and directs their binding to cAMP response elements. Proc Natl Acad Sci U S A (1993) 2.09
A novel oncogene, ost, encodes a guanine nucleotide exchange factor that potentially links Rho and Rac signaling pathways. EMBO J (1994) 2.09
MyoD induces growth arrest independent of differentiation in normal and transformed cells. Proc Natl Acad Sci U S A (1990) 2.07
Pulmonary tuberculosis: CT findings--early active disease and sequential change with antituberculous therapy. Radiology (1993) 2.06
Support for Barker hypothesis upheld in rat model of maternal undernutrition during the preimplantation period: application of integrated 'random effects' statistical model. Reprod Biomed Online (2004) 2.06
Male sterility and enhanced radiation sensitivity in TLS(-/-) mice. EMBO J (2000) 2.05
Interaction of frizzled related protein (FRP) with Wnt ligands and the frizzled receptor suggests alternative mechanisms for FRP inhibition of Wnt signaling. J Biol Chem (1999) 2.05
Association between angiotensin II receptor gene polymorphism and serum angiotensin converting enzyme (SACE) activity in patients with sarcoidosis. Thorax (1998) 2.04
toxB gene on pO157 of enterohemorrhagic Escherichia coli O157:H7 is required for full epithelial cell adherence phenotype. Infect Immun (2001) 2.04
Body fat mass and lean mass as predictors of survival in hemodialysis patients. Kidney Int (2006) 2.04
Accumulation of GTP-bound RhoA during cytokinesis and a critical role of ECT2 in this accumulation. J Biol Chem (2000) 2.04
Solid organ transplantation from hepatitis B virus-positive donors: consensus guidelines for recipient management. Am J Transplant (2015) 2.03
Rearrangement of the transcription factor gene CHOP in myxoid liposarcomas with t(12;16)(q13;p11). Genes Chromosomes Cancer (1992) 1.99
The genetics of alkaline phosphatase formation in Bacillus subtilis. Genetics (1965) 1.96
Regulation of keratinocyte growth factor gene expression by interleukin 1. J Biol Chem (1994) 1.95
Mammaglobin, a mammary-specific member of the uteroglobin gene family, is overexpressed in human breast cancer. Cancer Res (1996) 1.95
Eps8, a substrate for the epidermal growth factor receptor kinase, enhances EGF-dependent mitogenic signals. EMBO J (1993) 1.92
Hypersensitivity to Hg2+ and hyperbinding activity associated with cloned fragments of the mercurial resistance operon of plasmid NR1. J Bacteriol (1979) 1.90
Organization of the lexA gene of Escherichia coli and nucleotide sequence of the regulatory region. Nucleic Acids Res (1981) 1.90
Prevention of acute renal failure in traumatic rhabdomyolysis. Arch Intern Med (1984) 1.88