Published in Mol Cell Biol on July 01, 2006
Functional integration of transcriptional and RNA processing machineries. Curr Opin Cell Biol (2008) 2.38
TCERG1 regulates alternative splicing of the Bcl-x gene by modulating the rate of RNA polymerase II transcription. Mol Cell Biol (2011) 0.93
DNA methylation biomarker candidates for early detection of colon cancer. Tumour Biol (2012) 0.88
The transcriptional transactivator Tat selectively regulates viral splicing. Nucleic Acids Res (2009) 0.88
Tat-SF1 is not required for Tat transactivation but does regulate the relative levels of unspliced and spliced HIV-1 RNAs. PLoS One (2009) 0.88
Dimerization and a novel Tax speckled structure localization signal are required for Tax nuclear localization. J Virol (2009) 0.87
Transcription elongation regulator 1 is a co-integrator of the cell fate determination factor Dachshund homolog 1. J Biol Chem (2010) 0.86
Transcription elongation regulator 1 (TCERG1) regulates competent RNA polymerase II-mediated elongation of HIV-1 transcription and facilitates efficient viral replication. Retrovirology (2013) 0.83
Identification of Tat-SF1 cellular targets by exon array analysis reveals dual roles in transcription and splicing. RNA (2011) 0.82
The FF4 and FF5 domains of transcription elongation regulator 1 (TCERG1) target proteins to the periphery of speckles. J Biol Chem (2012) 0.81
Specific interaction of the transcription elongation regulator TCERG1 with RNA polymerase II requires simultaneous phosphorylation at Ser2, Ser5, and Ser7 within the carboxyl-terminal domain repeat. J Biol Chem (2013) 0.81
Differential effects of sumoylation on transcription and alternative splicing by transcription elongation regulator 1 (TCERG1). J Biol Chem (2010) 0.81
Crystal structure of the three tandem FF domains of the transcription elongation regulator CA150. J Mol Biol (2009) 0.79
The pathology of pre-mRNA splicing: a meeting in the Italian Alps. Workshop on pre-mRNA processing and disease. EMBO Rep (2007) 0.78
Prp40 pre-mRNA processing factor 40 homolog B (PRPF40B) associates with SF1 and U2AF65 and modulates alternative pre-mRNA splicing in vivo. RNA (2015) 0.78
The in vivo dynamics of TCERG1, a factor that couples transcriptional elongation with splicing. RNA (2016) 0.78
Functional Consequences for Apoptosis by Transcription Elongation Regulator 1 (TCERG1)-Mediated Bcl-x and Fas/CD95 Alternative Splicing. PLoS One (2015) 0.75
Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res (1983) 124.30
pEF-BOS, a powerful mammalian expression vector. Nucleic Acids Res (1990) 12.75
Different phosphorylated forms of RNA polymerase II and associated mRNA processing factors during transcription. Genes Dev (2000) 10.64
Integrating mRNA processing with transcription. Cell (2002) 9.74
High mobility of proteins in the mammalian cell nucleus. Nature (2000) 9.39
The C-terminal domain of RNA polymerase II couples mRNA processing to transcription. Nature (1997) 8.86
A unified theory of gene expression. Cell (2002) 7.61
Nuclear speckles: a model for nuclear organelles. Nat Rev Mol Cell Biol (2003) 6.98
Transcription elongation factor P-TEFb is required for HIV-1 tat transactivation in vitro. Genes Dev (1997) 6.88
Comprehensive proteomic analysis of the human spliceosome. Nature (2002) 6.85
Control of RNA polymerase II elongation potential by a novel carboxyl-terminal domain kinase. J Biol Chem (1996) 6.78
5'-Capping enzymes are targeted to pre-mRNA by binding to the phosphorylated carboxy-terminal domain of RNA polymerase II. Genes Dev (1997) 6.68
RNA polymerase II and the integration of nuclear events. Genes Dev (2000) 6.16
Macromolecular domains within the cell nucleus. Annu Rev Cell Biol (1993) 5.90
mRNA capping enzyme is recruited to the transcription complex by phosphorylation of the RNA polymerase II carboxy-terminal domain. Genes Dev (1997) 5.77
Purification of P-TEFb, a transcription factor required for the transition into productive elongation. J Biol Chem (1995) 5.31
P-TEFb kinase is required for HIV Tat transcriptional activation in vivo and in vitro. Genes Dev (1997) 5.13
Multiple links between transcription and splicing. RNA (2004) 4.90
Human general transcription factor IIH phosphorylates the C-terminal domain of RNA polymerase II. Nature (1992) 4.63
The C-terminal domain of the largest subunit of RNA polymerase II interacts with a novel set of serine/arginine-rich proteins. Proc Natl Acad Sci U S A (1996) 4.16
Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex. Nat Genet (1998) 4.16
Transcription-dependent redistribution of the large subunit of RNA polymerase II to discrete nuclear domains. J Cell Biol (1995) 4.13
Distinct roles for CTD Ser-2 and Ser-5 phosphorylation in the recruitment and allosteric activation of mammalian mRNA capping enzyme. Mol Cell (1999) 3.73
Tails of RNA polymerase II. Trends Biochem Sci (1990) 3.48
A hyperphosphorylated form of the large subunit of RNA polymerase II is associated with splicing complexes and the nuclear matrix. Proc Natl Acad Sci U S A (1996) 3.25
RNA polymerase II targets pre-mRNA splicing factors to transcription sites in vivo. Mol Cell (1999) 3.10
Phosphorylated RNA polymerase II stimulates pre-mRNA splicing. Genes Dev (1999) 3.00
HIV-1 Tat acts as a processivity factor in vitro in conjunction with cellular elongation factors. Genes Dev (1992) 2.85
Nuclear domains. J Cell Sci (2001) 2.74
Serine phosphorylation of SR proteins is required for their recruitment to sites of transcription in vivo. J Cell Biol (1998) 2.60
Immunoelectron microscopic localization of snRNPs. Biol Cell (1983) 2.57
Splicing factors associate with hyperphosphorylated RNA polymerase II in the absence of pre-mRNA. J Cell Biol (1997) 2.57
CTD kinase associated with yeast RNA polymerase II initiation factor b. Cell (1991) 2.48
Transcription elongation factor P-TEFb mediates Tat activation of HIV-1 transcription at multiple stages. EMBO J (1998) 2.45
Tat-SF1: cofactor for stimulation of transcriptional elongation by HIV-1 Tat. Science (1996) 2.42
Processing of endogenous pre-mRNAs in association with SC-35 domains is gene specific. J Cell Biol (1999) 2.24
Novel mechanism and factor for regulation by HIV-1 Tat. EMBO J (1995) 2.14
Positive patches and negative noodles: linking RNA processing to transcription? Trends Biochem Sci (1993) 2.12
Disruption of pre-mRNA splicing in vivo results in reorganization of splicing factors. J Cell Biol (1994) 2.12
Proteomic analysis of interchromatin granule clusters. Mol Biol Cell (2004) 2.12
Ultrastructural analysis of transcription and splicing in the cell nucleus after bromo-UTP microinjection. Mol Biol Cell (1999) 2.08
Co-transcriptional commitment to alternative splice site selection. Nucleic Acids Res (1998) 2.07
The splicing factor, Prp40, binds the phosphorylated carboxyl-terminal domain of RNA polymerase II. J Biol Chem (2000) 2.07
p54(nrb) associates with the 5' splice site within large transcription/splicing complexes. EMBO J (2004) 2.06
Co-transcriptional splicing of pre-messenger RNAs: considerations for the mechanism of alternative splicing. Gene (2001) 2.02
Structural basis for the molecular recognition between human splicing factors U2AF65 and SF1/mBBP. Mol Cell (2003) 2.00
Purification and biochemical characterization of interchromatin granule clusters. EMBO J (1999) 1.99
A functional interaction between the carboxy-terminal domain of RNA polymerase II and pre-mRNA splicing. J Cell Biol (1997) 1.91
Three-dimensional visualization of transcription sites and their association with splicing factor-rich nuclear speckles. J Cell Biol (1999) 1.87
The Cdk9 and cyclin T subunits of TAK/P-TEFb localize to splicing factor-rich nuclear speckle regions. J Cell Sci (2001) 1.82
Antagonistic effects of T-Ag and VP16 reveal a role for RNA pol II elongation on alternative splicing. EMBO J (2001) 1.76
The FF domain: a novel motif that often accompanies WW domains. Trends Biochem Sci (1999) 1.73
The transcription elongation factor CA150 interacts with RNA polymerase II and the pre-mRNA splicing factor SF1. Mol Cell Biol (2001) 1.64
A nuclear matrix protein interacts with the phosphorylated C-terminal domain of RNA polymerase II. Mol Cell Biol (1998) 1.59
MAZ elements alter transcription elongation and silencing of the fibroblast growth factor receptor 2 exon IIIb. J Biol Chem (2004) 1.52
CUS2, a yeast homolog of human Tat-SF1, rescues function of misfolded U2 through an unusual RNA recognition motif. Mol Cell Biol (1998) 1.52
Allosteric interactions between capping enzyme subunits and the RNA polymerase II carboxy-terminal domain. Genes Dev (1998) 1.49
Participation of the C-terminal domain of RNA polymerase II in exon definition during pre-mRNA splicing. Mol Cell Biol (2000) 1.48
Hyperphosphorylated C-terminal repeat domain-associating proteins in the nuclear proteome link transcription to DNA/chromatin modification and RNA processing. Mol Cell Proteomics (2002) 1.41
A comprehensive study on the isolation and characterization of the HeLa S3 nuclear matrix. J Cell Sci (1991) 1.39
Protein-interaction modules that organize nuclear function: FF domains of CA150 bind the phosphoCTD of RNA polymerase II. Proc Natl Acad Sci U S A (2000) 1.36
CA150, a nuclear protein associated with the RNA polymerase II holoenzyme, is involved in Tat-activated human immunodeficiency virus type 1 transcription. Mol Cell Biol (1997) 1.36
The WW domain-containing proteins interact with the early spliceosome and participate in pre-mRNA splicing in vivo. Mol Cell Biol (2004) 1.33
A serine/arginine-rich nuclear matrix cyclophilin interacts with the C-terminal domain of RNA polymerase II. Nucleic Acids Res (1997) 1.31
Coupled in vitro synthesis and splicing of RNA polymerase II transcripts. RNA (2000) 1.29
The HIV-1 Tat cellular coactivator Tat-SF1 is a general transcription elongation factor. Genes Dev (1998) 1.27
Kinetic role for mammalian SF1/BBP in spliceosome assembly and function after polypyrimidine tract recognition by U2AF. J Biol Chem (2000) 1.16
Phosphorylation of RNA polymerase II CTD fragments results in tight binding to the WW domain from the yeast prolyl isomerase Ess1. Biochemistry (2001) 1.09
FF domains of CA150 bind transcription and splicing factors through multiple weak interactions. Mol Cell Biol (2004) 1.09
Transcriptional cofactor CA150 regulates RNA polymerase II elongation in a TATA-box-dependent manner. Mol Cell Biol (1999) 1.08
Heat shock-induced appearance of RNA polymerase II in karyoskeletal protein-enriched (nuclear "matrix") fractions correlates with transcriptional shutdown in Drosophila melanogaster. J Biol Chem (1989) 0.81
Expression analysis and mapping of the mouse and human transcriptional regulator CA150. Mamm Genome (2000) 0.78
Interleukin 7 receptor alpha chain (IL7R) shows allelic and functional association with multiple sclerosis. Nat Genet (2007) 5.09
Factors affecting reproducibility between genome-scale siRNA-based screens. J Biomol Screen (2010) 4.47
Autoregulation of polypyrimidine tract binding protein by alternative splicing leading to nonsense-mediated decay. Mol Cell (2004) 4.13
Reversible cross-linking combined with immunoprecipitation to study RNA-protein interactions in vivo. Methods (2002) 3.73
Discovery of insect and human dengue virus host factors. Nature (2009) 3.49
Circulating tumor cells from patients with advanced prostate and breast cancer display both epithelial and mesenchymal markers. Mol Cancer Res (2011) 3.25
RNAi-mediated PTB depletion leads to enhanced exon definition. Mol Cell (2002) 2.34
Fox-2 mediates epithelial cell-specific fibroblast growth factor receptor 2 exon choice. Mol Cell Biol (2006) 2.18
Phenotype correction of hemophilia A mice by spliceosome-mediated RNA trans-splicing. Nat Med (2003) 2.04
Partial correction of endogenous DeltaF508 CFTR in human cystic fibrosis airway epithelia by spliceosome-mediated RNA trans-splicing. Nat Biotechnol (2002) 1.96
Two yeast PUF proteins negatively regulate a single mRNA. J Biol Chem (2007) 1.63
A stem structure in fibroblast growth factor receptor 2 transcripts mediates cell-type-specific splicing by approximating intronic control elements. Mol Cell Biol (2003) 1.63
hnRNP H and hnRNP F complex with Fox2 to silence fibroblast growth factor receptor 2 exon IIIc. Mol Cell Biol (2008) 1.60
Quantitative mass spectrometry of DENV-2 RNA-interacting proteins reveals that the DEAD-box RNA helicase DDX6 binds the DB1 and DB2 3' UTR structures. RNA Biol (2011) 1.54
MAZ elements alter transcription elongation and silencing of the fibroblast growth factor receptor 2 exon IIIb. J Biol Chem (2004) 1.52
Alternative inclusion of fibroblast growth factor receptor 2 exon IIIc in Dunning prostate tumors reveals unexpected epithelial mesenchymal plasticity. Proc Natl Acad Sci U S A (2006) 1.36
Human Pumilio proteins recruit multiple deadenylases to efficiently repress messenger RNAs. J Biol Chem (2012) 1.27
Characterization of the intronic splicing silencers flanking FGFR2 exon IIIb. J Biol Chem (2005) 1.23
Quantification of alternatively spliced FGFR2 RNAs using the RNA invasive cleavage assay. RNA (2003) 1.23
Zika Virus: Diagnosis, Therapeutics, and Vaccine. ACS Infect Dis (2016) 1.15
5' exon replacement and repair by spliceosome-mediated RNA trans-splicing. RNA (2003) 1.13
Reprogramming of tau alternative splicing by spliceosome-mediated RNA trans-splicing: implications for tauopathies. Proc Natl Acad Sci U S A (2005) 1.10
Promoter influences transcription elongation: TATA-box element mediates the assembly of processive transcription complexes responsive to cyclin-dependent kinase 9. J Biol Chem (2008) 1.05
Of urchins and men: evolution of an alternative splicing unit in fibroblast growth factor receptor genes. RNA (2003) 1.03
Alternative splicing in multiple sclerosis and other autoimmune diseases. RNA Biol (2010) 1.02
G protein-coupled receptor kinase 2 promotes flaviviridae entry and replication. PLoS Negl Trop Dis (2012) 1.01
The polypyrimidine tract-binding protein is required for efficient dengue virus propagation and associates with the viral replication machinery. J Biol Chem (2009) 1.01
Fas-activated serine/threonine phosphoprotein (FAST) is a regulator of alternative splicing. Proc Natl Acad Sci U S A (2007) 1.00
In vitro coupled transcription splicing. Methods (2005) 0.99
Dunning rat prostate adenocarcinomas and alternative splicing reporters: powerful tools to study epithelial plasticity in prostate tumors in vivo. Clin Exp Metastasis (2008) 0.99
Drosophila Pumilio protein contains multiple autonomous repression domains that regulate mRNAs independently of Nanos and brain tumor. Mol Cell Biol (2011) 0.98
A protocol for imaging alternative splicing regulation in vivo using fluorescence reporters in transgenic mice. Nat Protoc (2007) 0.96
Functional coupling of transcription and splicing. Gene (2012) 0.95
The role of epithelial plasticity in prostate cancer dissemination and treatment resistance. Cancer Metastasis Rev (2014) 0.94
TCERG1 regulates alternative splicing of the Bcl-x gene by modulating the rate of RNA polymerase II transcription. Mol Cell Biol (2011) 0.93
A eukaryotic translation initiation factor 4E-binding protein promotes mRNA decapping and is required for PUF repression. Mol Cell Biol (2012) 0.92
The Carboxyl-terminal Domain of RNA Polymerase II Is Not Sufficient to Enhance the Efficiency of Pre-mRNA Capping or Splicing in the Context of a Different Polymerase. J Biol Chem (2009) 0.92
Development of a method to isolate circulating tumor cells using mesenchymal-based capture. Methods (2013) 0.92
Imaging alternative splicing in living cells. Methods Mol Biol (2004) 0.92
Flaviviral RNAs: weapons and targets in the war between virus and host. Biochem J (2014) 0.92
Identification of the cellular targets of the transcription factor TCERG1 reveals a prevalent role in mRNA processing. J Biol Chem (2008) 0.91
Correction of tau mis-splicing caused by FTDP-17 MAPT mutations by spliceosome-mediated RNA trans-splicing. Hum Mol Genet (2009) 0.91
The polypyrimidine tract binding protein is required for efficient picornavirus gene expression and propagation. J Virol (2005) 0.91
Imaging the alternative silencing of FGFR2 exon IIIb in vivo. RNA (2006) 0.90
Tat-SF1 is not required for Tat transactivation but does regulate the relative levels of unspliced and spliced HIV-1 RNAs. PLoS One (2009) 0.88
Identification of an intronic splicing enhancer essential for the inclusion of FGFR2 exon IIIc. J Biol Chem (2008) 0.88
SplicerAV: a tool for mining microarray expression data for changes in RNA processing. BMC Bioinformatics (2010) 0.87
Transcription elongation regulator 1 is a co-integrator of the cell fate determination factor Dachshund homolog 1. J Biol Chem (2010) 0.86
The kinase inhibitor SFV785 dislocates dengue virus envelope protein from the replication complex and blocks virus assembly. PLoS One (2011) 0.86
Initiation of human immunodeficiency virus type 1 (HIV-1) transcription is inhibited by noncytolytic CD8 suppression. Open Virol J (2007) 0.85
Transcription elongation regulator 1 (TCERG1) regulates competent RNA polymerase II-mediated elongation of HIV-1 transcription and facilitates efficient viral replication. Retrovirology (2013) 0.83
Trans-splicing into highly abundant albumin transcripts for production of therapeutic proteins in vivo. Mol Ther (2008) 0.83
Identification of Tat-SF1 cellular targets by exon array analysis reveals dual roles in transcription and splicing. RNA (2011) 0.82
Fluorescence-based alternative splicing reporters for the study of epithelial plasticity in vivo. RNA (2012) 0.82
Cleavage and polyadenylation specificity factor 1 (CPSF1) regulates alternative splicing of interleukin 7 receptor (IL7R) exon 6. RNA (2012) 0.81
Differential effects of sumoylation on transcription and alternative splicing by transcription elongation regulator 1 (TCERG1). J Biol Chem (2010) 0.81
The FF4 and FF5 domains of transcription elongation regulator 1 (TCERG1) target proteins to the periphery of speckles. J Biol Chem (2012) 0.81
A functional genetic approach suggests a novel interaction between the human immunodeficiency virus type 1 (HIV-1) Tat protein and HIV-1 TAR RNA in vivo. J Gen Virol (2003) 0.81
TIA nuclear proteins regulate the alternate splicing of lysyl hydroxylase 2. J Invest Dermatol (2008) 0.81
Using circulating tumor cells to inform on prostate cancer biology and clinical utility. Crit Rev Clin Lab Sci (2015) 0.80
Identification of dengue RNA binding proteins using RNA chromatography and quantitative mass spectrometry. Methods Mol Biol (2014) 0.80
Epstein-Barr virus induces global changes in cellular mRNA isoform usage that are important for the maintenance of latency. J Virol (2013) 0.79
A guide to design and optimization of reporter assays for 3' untranslated region mediated regulation of mammalian messenger RNAs. Methods (2013) 0.78
Functional genomics approach for the identification of human host factors supporting dengue viral propagation. Methods Mol Biol (2014) 0.77
Mending the message. Nat Biotechnol (2003) 0.77
DNA delivery via cationic solid lipid nanoparticles (SLNs). Eur J Pharm Sci (2013) 0.77
Shedding UV light on alternative splicing. Cell (2009) 0.77
Quantification of microRNAs, splicing isoforms, and homologous mRNAs with the invader assay. Methods Mol Biol (2008) 0.76
Assessing incomplete deprotection of microarray oligonucleotides in situ. Nucleic Acids Res (2006) 0.75
Spatial Organization and Dynamics of Transcription Elongation and Pre-mRNA Processing in Live Cells. Genet Res Int (2011) 0.75
In vitro analysis of RNA degradation catalyzed by deadenylase enzymes. Methods Mol Biol (2014) 0.75
Correction: G3BP1, G3BP2 and CAPRIN1 Are Required for Translation of Interferon Stimulated mRNAs and Are Targeted by a Dengue Virus Non-coding RNA. PLoS Pathog (2017) 0.75
Corrigendum: Alternative splicing promotes tumour aggressiveness and drug resistance in African American prostate cancer. Nat Commun (2017) 0.75
Gene Control during Transcription Elongation. Genet Res Int (2012) 0.75
A neutravidin-based assay for reverse transcriptase suitable for high throughput screening of retroviral activity. J Biochem Mol Biol (2002) 0.75