Published in Proc Natl Acad Sci U S A on December 01, 1991
Meiotic recombination break points resolve at high rates at the 5' end of a maize coding sequence. Plant Cell (1995) 1.89
SNP microarray analysis for genome-wide detection of crossover regions. Hum Genet (2005) 1.68
Predictive testing for multiple endocrine neoplasia type 1 using DNA polymorphisms. J Clin Invest (1992) 1.10
Deletion and translocation of chromosome 11q13 sequences in cervical carcinoma cell lines. Am J Hum Genet (1995) 1.05
Exhaustive mutation scanning by fluorescence-assisted mismatch analysis discloses new genotype-phenotype correlations in angiodema. Am J Hum Genet (1996) 1.04
Oesophageal cancer and amplification of the human cyclin D gene CCND1/PRAD1. Br J Cancer (1995) 1.01
Mapping the gene for hereditary hyperparathyroidism and prolactinoma (MEN1Burin) to chromosome 11q: evidence for a founder effect in patients from Newfoundland. Am J Hum Genet (1994) 0.92
Alleles of the hotspot cog are codominant in effect on recombination in the his-3 region of Neurospora. Genetics (2004) 0.86
Schizophrenia-associated chromosome 11q21 translocation: identification of flanking markers and development of chromosome 11q fragment hybrids as cloning and mapping resources. Am J Hum Genet (1993) 0.80
A 3-Mb contig from D11S987 to MLK3, a gene-rich region in 11q13. Genome Res (1997) 0.78
An interstitial telomere array proximal to the distal telomere of mouse chromosome 13. Mamm Genome (1997) 0.75
A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal Biochem (1983) 206.01
Genomic sequencing. Proc Natl Acad Sci U S A (1984) 92.36
Mutation and cancer: statistical study of retinoblastoma. Proc Natl Acad Sci U S A (1971) 31.05
CpG-rich islands and the function of DNA methylation. Nature (1986) 24.90
Amplification of human minisatellites by the polymerase chain reaction: towards DNA fingerprinting of single cells. Nucleic Acids Res (1988) 8.33
Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus. Cell (1990) 8.30
Deletions and a translocation interrupt a cloned gene at the neurofibromatosis type 1 locus. Cell (1990) 6.94
A highly polymorphic locus in human DNA revealed by cosmid-derived probes. Proc Natl Acad Sci U S A (1985) 5.81
Genetic aspects of adenomatosis of endocrine glands. Am J Med (1954) 4.60
The chromosomal basis of human neoplasia. Science (1983) 4.26
Multiple endocrine neoplasia type 1 gene maps to chromosome 11 and is lost in insulinoma. Nature (1988) 3.96
Constitutive fragile sites and cancer. Science (1984) 3.30
cDNA sequence of human transforming gene hst and identification of the coding sequence required for transforming activity. Proc Natl Acad Sci U S A (1987) 2.97
Clustering of breakpoints on chromosome 11 in human B-cell neoplasms with the t(11;14) chromosome translocation. Nature (1985) 2.91
A large inverted duplication allows homologous recombination between chromosomes heterozygous for the proximal t complex inversion. Cell (1987) 2.88
Linkage between immunoglobulin E responses underlying asthma and rhinitis and chromosome 11q. Lancet (1989) 2.85
Human C1 inhibitor: primary structure, cDNA cloning, and chromosomal localization. Biochemistry (1986) 2.52
A fine-structure deletion map of human chromosome 11p: analysis of J1 series hybrids. Somat Cell Mol Genet (1989) 2.29
A detailed genetic map of the long arm of chromosome 11. Genomics (1990) 2.11
A 10-megabase physical map of human Xp21, including the Duchenne muscular dystrophy gene. Genomics (1988) 2.04
Isolation and structure of a cDNA encoding the B1 (CD20) cell-surface antigen of human B lymphocytes. Proc Natl Acad Sci U S A (1988) 1.93
Characterization and chromosome assignment of the human homolog of int-2, a potential proto-oncogene. Mol Cell Biol (1986) 1.90
Clonality of parathyroid tumors in familial multiple endocrine neoplasia type 1. N Engl J Med (1989) 1.64
Isolation and mapping of 62 new RFLP markers on human chromosome 11. Am J Hum Genet (1991) 1.52
Association of parathyroid tumors in multiple endocrine neoplasia type 1 with loss of alleles on chromosome 11. N Engl J Med (1989) 1.52
Intron/exon structure of the human gene for the muscle isozyme of glycogen phosphorylase. Proteins (1987) 1.42
Localization of the MEN1 gene to a small region within chromosome 11q13 by deletion mapping in tumors. Proc Natl Acad Sci U S A (1990) 1.36
Localization of the genetic defect in multiple endocrine neoplasia type 1 within a small region of chromosome 11. Am J Hum Genet (1989) 1.24
High incidence of chromosome abnormalities in IgG3 myeloma. Cancer Genet Cytogenet (1984) 1.11
Genes and pseudogenes for human U2 RNA. Implications for the mechanism of pseudogene formation. J Mol Biol (1984) 1.09
Variable numbers of pepsinogen genes are located in the centromeric region of human chromosome 11 and determine the high-frequency electrophoretic polymorphism. Proc Natl Acad Sci U S A (1985) 1.06
Two new cell lines from B-prolymphocytic leukaemia: characterization by morphology, immunological markers, karyotype and Ig gene rearrangement. Int J Cancer (1986) 1.02
Localization of the gene encoding a type I protein phosphatase catalytic subunit to human chromosome band 11q13. Genomics (1990) 0.97
The FGF-related oncogenes hst and int.2, and the bcl.1 locus are contained within one megabase in band q13 of chromosome 11, while the fgf.5 oncogene maps to 4q21. Oncogene (1988) 0.96
Isolation and mapping of a polymorphic DNA sequence for human muscle glycogen phosphorylase (pMCMP1) on chromosome II [PYGM]. Nucleic Acids Res (1988) 0.94
A physical map around the WAGR complex on the short arm of chromosome 11. Genomics (1989) 0.94
Isolation and mapping of a polymorphic DNA sequence (pTHH26) on chromosome 11 [D11S149]. Nucleic Acids Res (1988) 0.92
Isolation and mapping of a polymorphic DNA sequence pHBI59 on chromosome 11 [D11S146]. Nucleic Acids Res (1988) 0.90
A panel of irradiation-reduced hybrids selectively retaining human chromosome 11p13: their structure and use to purify the WAGR gene complex. Genomics (1990) 0.85
The 11q13 amplicon of a mammary carcinoma cell line. Genes Chromosomes Cancer (1990) 0.79
Genetic alterations during colorectal-tumor development. N Engl J Med (1988) 26.82
Variable number of tandem repeat (VNTR) markers for human gene mapping. Science (1987) 25.71
Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas. Science (1989) 11.53
Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients. Science (1991) 9.89
Degenerate oligonucleotide-primed PCR: general amplification of target DNA by a single degenerate primer. Genomics (1992) 9.06
Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus. Cell (1990) 8.30
Quantum computers. Nature (2010) 6.79
A Practical Classification of the Monilias. J Bacteriol (1937) 6.36
A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damage. Nature (2000) 6.01
When is cancer pain mild, moderate or severe? Grading pain severity by its interference with function. Pain (1995) 5.97
Isolation and localization of DNA segments from specific human chromosomes. Proc Natl Acad Sci U S A (1980) 5.76
p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53. Cell (2000) 5.64
Allelotype of colorectal carcinomas. Science (1989) 5.54
The action of tetrodotoxin on electrogenic components of squid giant axons. J Gen Physiol (1965) 5.42
Serum creatinine levels in the US population: third National Health and Nutrition Examination Survey. Am J Kidney Dis (1998) 5.28
AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1. Nat Genet (2000) 5.26
Interleukin-2 receptor gamma chain: a functional component of the interleukin-7 receptor. Science (1993) 5.22
Somatic mutations of the APC gene in colorectal tumors: mutation cluster region in the APC gene. Hum Mol Genet (1992) 5.14
Human mitochondrial DNA deletions associated with mutations in the gene encoding Twinkle, a phage T7 gene 4-like protein localized in mitochondria. Nat Genet (2001) 5.09
Complete genome structure of the nitrogen-fixing symbiotic bacterium Mesorhizobium loti. DNA Res (2000) 4.94
Interleukin-2 receptor gamma chain: a functional component of the interleukin-4 receptor. Science (1993) 4.63
Rapid colorectal adenoma formation initiated by conditional targeting of the Apc gene. Science (1997) 4.62
Case definitions, diagnostic algorithms, and priorities in encephalitis: consensus statement of the international encephalitis consortium. Clin Infect Dis (2013) 4.51
The gene for familial polyposis coli maps to the long arm of chromosome 5. Science (1987) 4.48
Detection of an unstable fragment of DNA specific to individuals with myotonic dystrophy. Nature (1992) 4.44
Transient regulation of protein synthesis in Escherichia coli upon shift-up of growth temperature. J Bacteriol (1978) 4.38
Complete genomic sequence of the filamentous nitrogen-fixing cyanobacterium Anabaena sp. strain PCC 7120. DNA Res (2001) 4.27
A primary genetic map of markers of human chromosome 10. Genomics (1988) 4.23
Disruption of the APC gene by a retrotransposal insertion of L1 sequence in a colon cancer. Cancer Res (1992) 4.21
Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans and genomic sequence comparison with Bacillus subtilis. Nucleic Acids Res (2000) 4.11
Loss-of-heterozygosity analysis of small-cell lung carcinomas using single-nucleotide polymorphism arrays. Nat Biotechnol (2000) 4.10
Identification and characterization of the potential promoter regions of 1031 kinds of human genes. Genome Res (2001) 4.03
Multiple endocrine neoplasia type 1 gene maps to chromosome 11 and is lost in insulinoma. Nature (1988) 3.96
Prediction of the risk of hereditary retinoblastoma, using DNA polymorphisms within the retinoblastoma gene. N Engl J Med (1988) 3.90
An ancient retrotransposal insertion causes Fukuyama-type congenital muscular dystrophy. Nature (1998) 3.86
Phase III trial comparing whole-pelvic versus prostate-only radiotherapy and neoadjuvant versus adjuvant combined androgen suppression: Radiation Therapy Oncology Group 9413. J Clin Oncol (2003) 3.73
Localization of the structural gene for human apolipoprotein A-I on the long arm of human chromosome 11. Proc Natl Acad Sci U S A (1984) 3.70
Natural history and life expectancy in severe alpha1-antitrypsin deficiency, Pi Z. Acta Med Scand (1978) 3.58
Mutation analysis of the BRCA2 gene in 49 site-specific breast cancer families. Nat Genet (1996) 3.56
Virus-induced neuronal apoptosis blocked by the herpes simplex virus latency-associated transcript. Science (2000) 3.51
Diverse transcriptional initiation revealed by fine, large-scale mapping of mRNA start sites. EMBO Rep (2001) 3.47
Results of surgical and nonsurgical treatment for small-sized hepatocellular carcinomas: a retrospective and nationwide survey in Japan. The Liver Cancer Study Group of Japan. Hepatology (2000) 3.42
Identification of the familial cylindromatosis tumour-suppressor gene. Nat Genet (2000) 3.42
Role of the SulB (FtsZ) protein in division inhibition during the SOS response in Escherichia coli: FtsZ stabilizes the inhibitor SulA in maxicells. Proc Natl Acad Sci U S A (1985) 3.31
Altered urinary bladder function in mice lacking the vanilloid receptor TRPV1. Nat Neurosci (2002) 3.28
Further changes in differentiation state accompanying the conversion of Chinese hamster cells of fibroblastic form by dibutyryl adenosine cyclic 3':5'-monophosphate and hormones. Proc Natl Acad Sci U S A (1971) 3.23
Identification of a Pax paired domain recognition sequence and evidence for DNA-dependent conformational changes. J Biol Chem (1994) 3.22
Rapid confirmation of single copy lambda prophage integration by PCR. Nucleic Acids Res (1994) 3.19
Genome-wide analysis of gene expression in human hepatocellular carcinomas using cDNA microarray: identification of genes involved in viral carcinogenesis and tumor progression. Cancer Res (2001) 3.18
A high-throughput SNP typing system for genome-wide association studies. J Hum Genet (2001) 3.18
Isolation and mapping of a polymorphic DNA sequence (pTHH22) on chromosome 9 [D9S12]. Nucleic Acids Res (1988) 3.17
IL-6 is produced by osteoblasts and induces bone resorption. J Immunol (1990) 3.14
Gene organization deduced from the complete sequence of liverwort Marchantia polymorpha mitochondrial DNA. A primitive form of plant mitochondrial genome. J Mol Biol (1992) 3.11
Microsatellite libraries enriched for several microsatellite sequences in plants. Biotechniques (1996) 3.08
HRPT2, encoding parafibromin, is mutated in hyperparathyroidism-jaw tumor syndrome. Nat Genet (2002) 3.07
Math5 is required for retinal ganglion cell and optic nerve formation. Development (2001) 3.07
Precise localization of human beta-globin gene complex on chromosome 11. Proc Natl Acad Sci U S A (1979) 3.05
Quality of Scottish Morbidity Record (SMR) data. Health Bull (Edinb) (1996) 3.05
Cytogenetic analysis by chromosome painting using DOP-PCR amplified flow-sorted chromosomes. Genes Chromosomes Cancer (1992) 3.03
An internal deletion within an 11p13 zinc finger gene contributes to the development of Wilms' tumor. Cell (1990) 3.02
Two independent and interactive DNA-binding subdomains of the Pax6 paired domain are regulated by alternative splicing. Genes Dev (1994) 2.99
Molecular detection of microscopic and submicroscopic deletions associated with Miller-Dieker syndrome. Am J Hum Genet (1988) 2.97
Mapping of mutation causing Friedreich's ataxia to human chromosome 9. Nature (1988) 2.96
Six-month outcome of critically ill patients given glutamine-supplemented parenteral nutrition. Nutrition (1997) 2.92
BRCA2 mutations in primary breast and ovarian cancers. Nat Genet (1996) 2.91
A tripeptide 'anticodon' deciphers stop codons in messenger RNA. Nature (2000) 2.90
Localisation of atopy and beta subunit of high-affinity IgE receptor (Fc epsilon RI) on chromosome 11q. Lancet (1993) 2.88
Specific deficit of the ON response in visual transmission by targeted disruption of the mGluR6 gene. Cell (1995) 2.81
A mapped set of genetic markers for human chromosome 9. Genomics (1988) 2.80
Loss of constitutional heterozygosity in human cancer. Annu Rev Genet (1991) 2.77
Genetic mapping of autosomal dominant Charcot-Marie-Tooth disease in a large French-Acadian kindred: identification of new linked markers on chromosome 17. Am J Hum Genet (1990) 2.77
Mutation in Npps in a mouse model of ossification of the posterior longitudinal ligament of the spine. Nat Genet (1998) 2.77
Experimental investigation of geologically produced antineutrinos with KamLAND. Nature (2005) 2.75
Human estrogen receptor beta-gene structure, chromosomal localization, and expression pattern. J Clin Endocrinol Metab (1997) 2.73
Correlation between the location of germ-line mutations in the APC gene and the number of colorectal polyps in familial adenomatous polyposis patients. Cancer Res (1992) 2.72
A primary genetic linkage map for human chromosome 12. Genomics (1987) 2.72
Recalibration of the delirium prediction model for ICU patients (PRE-DELIRIC): a multinational observational study. Intensive Care Med (2014) 2.71
Prevalence of high blood pressure and elevated serum creatinine level in the United States: findings from the third National Health and Nutrition Examination Survey (1988-1994). Arch Intern Med (2001) 2.69
Requirement of CD9 on the egg plasma membrane for fertilization. Science (2000) 2.65
Enhanced expression of a glyceraldehyde-3-phosphate dehydrogenase gene in human lung cancers. Cancer Res (1987) 2.65
Clinical and genetic studies of Birt-Hogg-Dubé syndrome. J Med Genet (2002) 2.65
Complete structure of the chloroplast genome of Arabidopsis thaliana. DNA Res (1999) 2.63
Mutations of the APC (adenomatous polyposis coli) gene. Hum Mutat (1993) 2.63
A new mutation, aly, that induces a generalized lack of lymph nodes accompanied by immunodeficiency in mice. Eur J Immunol (1994) 2.62
Impairment of suckling response, trigeminal neuronal pattern formation, and hippocampal LTD in NMDA receptor epsilon 2 subunit mutant mice. Neuron (1996) 2.62
Relationship between dopamine D(2) occupancy, clinical response, and side effects: a double-blind PET study of first-episode schizophrenia. Am J Psychiatry (2000) 2.61
Biosynthesis of vitamin B12: identity of fragment extruded during ring contraction to the corrin macrocycle. Proc Natl Acad Sci U S A (1981) 2.60
Fli-1 is required for murine vascular and megakaryocytic development and is hemizygously deleted in patients with thrombocytopenia. Immunity (2000) 2.59
Allelotype of breast cancer: cumulative allele losses promote tumor progression in primary breast cancer. Cancer Res (1990) 2.57
A radiation hybrid map of the rat genome containing 5,255 markers. Nat Genet (1999) 2.54
Extracellular ATP or ADP induce chemotaxis of cultured microglia through Gi/o-coupled P2Y receptors. J Neurosci (2001) 2.54
Association studies of 33 single nucleotide polymorphisms (SNPs) in 29 candidate genes for bronchial asthma: positive association a T924C polymorphism in the thromboxane A2 receptor gene. Hum Genet (2000) 2.50
p53DINP1, a p53-inducible gene, regulates p53-dependent apoptosis. Mol Cell (2001) 2.47
Helium-3 emission related to volcanic activity. Science (1984) 2.43