Published in Nature on July 13, 2006
Myosin Vb mobilizes recycling endosomes and AMPA receptors for postsynaptic plasticity. Cell (2008) 3.73
Cargo transport: molecular motors navigate a complex cytoskeleton. Curr Opin Cell Biol (2008) 2.39
Kinesin-1 structural organization and conformational changes revealed by FRET stoichiometry in live cells. J Cell Biol (2007) 2.08
Walking to work: roles for class V myosins as cargo transporters. Nat Rev Mol Cell Biol (2011) 1.93
Myosin V from head to tail. Cell Mol Life Sci (2008) 1.76
Myosin V, Rab11, and dRip11 direct apical secretion and cellular morphogenesis in developing Drosophila photoreceptors. J Cell Biol (2007) 1.76
In the right place at the right time: visualizing and understanding mRNA localization. Nat Rev Mol Cell Biol (2014) 1.72
Head-head and head-tail interaction: a general mechanism for switching off myosin II activity in cells. Mol Biol Cell (2008) 1.70
How are the cellular functions of myosin VI regulated within the cell? Biochem Biophys Res Commun (2007) 1.58
Myosin VI is required for sorting of AP-1B-dependent cargo to the basolateral domain in polarized MDCK cells. J Cell Biol (2007) 1.51
Direct observation of the mechanochemical coupling in myosin Va during processive movement. Nature (2008) 1.51
Myosin V transports secretory vesicles via a Rab GTPase cascade and interaction with the exocyst complex. Dev Cell (2011) 1.50
Direct interaction between a myosin V motor and the Rab GTPases Ypt31/32 is required for polarized secretion. Mol Biol Cell (2008) 1.45
Rapid glucose depletion immobilizes active myosin V on stabilized actin cables. Curr Biol (2014) 1.41
The globular tail domain puts on the brake to stop the ATPase cycle of myosin Va. Proc Natl Acad Sci U S A (2008) 1.31
Single-molecule stepping and structural dynamics of myosin X. Nat Struct Mol Biol (2010) 1.31
A FERM domain autoregulates Drosophila myosin 7a activity. Proc Natl Acad Sci U S A (2009) 1.29
Regulating cytoskeleton-based vesicle motility. FEBS Lett (2007) 1.28
Load and Pi control flux through the branched kinetic cycle of myosin V. J Biol Chem (2008) 1.24
The microtubule plus-end localization of Aspergillus dynein is important for dynein-early-endosome interaction but not for dynein ATPase activation. J Cell Sci (2010) 1.17
The structure of the Myo4p globular tail and its function in ASH1 mRNA localization. J Cell Biol (2010) 1.17
Basic mechanisms for recognition and transport of synaptic cargos. Mol Brain (2009) 1.13
Myosin-V is activated by binding secretory cargo and released in coordination with Rab/exocyst function. Dev Cell (2012) 1.08
Motor transport of self-assembled cargos in crowded environments. Proc Natl Acad Sci U S A (2012) 1.06
Myosin IIIB uses an actin-binding motif in its espin-1 cargo to reach the tips of actin protrusions. Curr Biol (2012) 1.05
Monomeric myosin V uses two binding regions for the assembly of stable translocation complexes. Proc Natl Acad Sci U S A (2007) 1.05
Myosin motors at neuronal synapses: drivers of membrane transport and actin dynamics. Nat Rev Neurosci (2013) 0.97
The role of actin remodeling in the trafficking of intracellular vesicles, transporters, and channels: focusing on aquaporin-2. Pflugers Arch (2007) 0.94
Identification and characterization of multiple novel Rab-myosin Va interactions. Mol Biol Cell (2013) 0.94
Myosin Va enhances secretion of herpes simplex virus 1 virions and cell surface expression of viral glycoproteins. J Virol (2010) 0.93
Nuclear and spindle positioning during oocyte meiosis. Curr Opin Cell Biol (2010) 0.93
Structural basis of myosin V Rab GTPase-dependent cargo recognition. Proc Natl Acad Sci U S A (2013) 0.91
A novel allele of myosin VIIa reveals a critical function for the C-terminal FERM domain for melanosome transport in retinal pigment epithelial cells. J Neurosci (2009) 0.91
Calcium-activated Myosin V closes the Drosophila pupil. Curr Biol (2008) 0.90
Structural insights into functional overlapping and differentiation among myosin V motors. J Biol Chem (2013) 0.90
Calmodulin bound to the first IQ motif is responsible for calcium-dependent regulation of myosin 5a. J Biol Chem (2012) 0.88
More than just a cargo adapter, melanophilin prolongs and slows processive runs of myosin Va. J Biol Chem (2013) 0.88
Motor proteins and molecular motors: how to operate machines at the nanoscale. J Phys Condens Matter (2013) 0.87
Functions of class V myosins in neurons. J Biol Chem (2013) 0.85
Lever-arm mechanics of processive myosins. Biophys J (2011) 0.85
Structure and Regulation of the Movement of Human Myosin VIIA. J Biol Chem (2015) 0.85
Full-length myosin Va exhibits altered gating during processive movement on actin. Proc Natl Acad Sci U S A (2012) 0.84
Calcium can mobilize and activate myosin-VI. Proc Natl Acad Sci U S A (2016) 0.84
Extensibility of the extended tail domain of processive and nonprocessive myosin V molecules. Biophys J (2009) 0.84
Various Themes of Myosin Regulation. J Mol Biol (2016) 0.83
Structural insights into the globular tails of the human type v myosins Myo5a, Myo5b, And Myo5c. PLoS One (2013) 0.83
Head-to-tail regulation is critical for the in vivo function of myosin V. J Cell Biol (2015) 0.83
Nucleotide-dependent shape changes in the reverse direction motor, myosin VI. Biophys J (2010) 0.83
The mammalian dynein-dynactin complex is a strong opponent to kinesin in a tug-of-war competition. Nat Cell Biol (2016) 0.83
Melanophilin Stimulates Myosin-5a Motor Function by Allosterically Inhibiting the Interaction between the Head and Tail of Myosin-5a. Sci Rep (2015) 0.82
Slip sliding away with myosin V. Proc Natl Acad Sci U S A (2007) 0.81
Plant-Specific Myosin XI, a Molecular Perspective. Front Plant Sci (2012) 0.79
The SH3 domain of a M7 interacts with its C-terminal proline-rich region. Protein Sci (2006) 0.79
Kinetic Adaptations of Myosins for Their Diverse Cellular Functions. Traffic (2016) 0.79
The Globular Tail Domain of Myosin-5a Functions as a Dimer in Regulating the Motor Activity. J Biol Chem (2016) 0.78
Identification of the Isoform-specific Interactions between the Tail and the Head of Class V Myosin. J Biol Chem (2016) 0.78
Myosin light chains: Teaching old dogs new tricks. Bioarchitecture (2014) 0.77
An approach to automated acquisition of cryoEM images from lacey carbon grids. J Struct Biol (2010) 0.76
Interaction between MyRIP and the actin cytoskeleton regulates Weibel-Palade body trafficking and exocytosis. J Cell Sci (2015) 0.76
Use of fluorescent techniques to study the in vitro movement of myosins. EXS (2014) 0.76
The path to visualization of walking myosin V by high-speed atomic force microscopy. Biophys Rev (2014) 0.76
Flexural Stiffness of Myosin Va Subdomains as Measured from Tethered Particle Motion. J Biophys (2015) 0.75
Coordinated recruitment of Spir actin nucleators and myosin V motors to Rab11 vesicle membranes. Elife (2016) 0.75
Myosin Va's adaptor protein melanophilin enforces track selection on the microtubule and actin networks in vitro. Proc Natl Acad Sci U S A (2017) 0.75
Loss of cargo binding in the human myosin VI deafness mutant (R1166X) leads to increased actin filament binding. Biochem J (2016) 0.75
Regular gaits and optimal velocities for motor proteins. Biophys J (2008) 0.75
SPIDER and WEB: processing and visualization of images in 3D electron microscopy and related fields. J Struct Biol (1996) 22.89
Myosin V walks hand-over-hand: single fluorophore imaging with 1.5-nm localization. Science (2003) 20.21
Brain myosin-V is a two-headed unconventional myosin with motor activity. Cell (1993) 5.24
Three-dimensional structural dynamics of myosin V by single-molecule fluorescence polarization. Nature (2003) 4.52
Three myosin V structures delineate essential features of chemo-mechanical transduction. EMBO J (2004) 3.21
Three conformational states of scallop myosin S1. Proc Natl Acad Sci U S A (2000) 3.06
Three-dimensional image reconstruction of dephosphorylated smooth muscle heavy meromyosin reveals asymmetry in the interaction between myosin heads and placement of subfragment 2. Proc Natl Acad Sci U S A (2001) 2.93
Direct observation of processive movement by individual myosin V molecules. Biochem Biophys Res Commun (2000) 2.83
Kinesin's IAK tail domain inhibits initial microtubule-stimulated ADP release. Nat Cell Biol (2000) 2.50
Myosin V: regulation by calcium, calmodulin, and the tail domain. J Cell Biol (2004) 2.40
Neck length and processivity of myosin V. J Biol Chem (2003) 2.23
The prepower stroke conformation of myosin V. J Cell Biol (2002) 2.12
Structural basis for myosin V discrimination between distinct cargoes. EMBO J (2006) 1.95
Regulated conformation of myosin V. J Biol Chem (2003) 1.90
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Myosin V motor proteins: marching stepwise towards a mechanism. J Cell Biol (2003) 1.63
Ca2+-induced activation of ATPase activity of myosin Va is accompanied with a large conformational change. Biochem Biophys Res Commun (2004) 1.46
Activation of myosin Va function by melanophilin, a specific docking partner of myosin Va. J Biol Chem (2005) 1.45
A folded (10 S) conformer of myosin from a striated muscle and its implications for regulation of ATPase activity. J Mol Biol (1991) 1.07
Motility of myosin V regulated by the dissociation of single calmodulin. Nat Struct Mol Biol (2005) 1.06
An elastically tethered viscous load imposes a regular gait on the motion of myosin-V. Simulation of the effect of transient force relaxation on a stochastic process. J R Soc Interface (2006) 1.01
Dissecting temporal and spatial control of cytokinesis with a myosin II Inhibitor. Science (2003) 12.41
Mechanism of blebbistatin inhibition of myosin II. J Biol Chem (2004) 5.45
The gated gait of the processive molecular motor, myosin V. Nat Cell Biol (2002) 5.34
Dynein structure and power stroke. Nature (2003) 4.25
Identification of an organelle receptor for myosin-Va. Nat Cell Biol (2002) 4.06
Load-dependent kinetics of myosin-V can explain its high processivity. Nat Cell Biol (2005) 3.69
Myosin-XVa is required for tip localization of whirlin and differential elongation of hair-cell stereocilia. Nat Cell Biol (2005) 3.15
Identification and characterization of nonmuscle myosin II-C, a new member of the myosin II family. J Biol Chem (2003) 2.98
Specificity of blebbistatin, an inhibitor of myosin II. J Muscle Res Cell Motil (2004) 2.96
AAA+ Ring and linker swing mechanism in the dynein motor. Cell (2009) 2.63
Blebbistatin, a myosin II inhibitor, is photoinactivated by blue light. Biochemistry (2005) 2.29
Neck length and processivity of myosin V. J Biol Chem (2003) 2.23
Effect of Smad7 expression on metastasis of mouse mammary carcinoma JygMC(A) cells. J Natl Cancer Inst (2005) 2.23
Kinetic mechanism of non-muscle myosin IIB: functional adaptations for tension generation and maintenance. J Biol Chem (2003) 2.19
The prepower stroke conformation of myosin V. J Cell Biol (2002) 2.12
The predicted coiled-coil domain of myosin 10 forms a novel elongated domain that lengthens the head. J Biol Chem (2005) 2.11
Functional divergence of human cytoplasmic myosin II: kinetic characterization of the non-muscle IIA isoform. J Biol Chem (2003) 2.03
Mutation of melanosome protein RAB38 in chocolate mice. Proc Natl Acad Sci U S A (2002) 2.02
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Actin-bundling protein TRIOBP forms resilient rootlets of hair cell stereocilia essential for hearing. Cell (2010) 1.94
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Regulated conformation of myosin V. J Biol Chem (2003) 1.90
Rab27a is an essential component of melanosome receptor for myosin Va. Mol Biol Cell (2002) 1.89
The clinical risk of vertebral artery injury from cervical pedicle screws inserted in degenerative vertebrae. Spine (Phila Pa 1976) (2005) 1.88
Disease-associated mutations and alternative splicing alter the enzymatic and motile activity of nonmuscle myosins II-B and II-C. J Biol Chem (2005) 1.86
Actin retrograde flow and actomyosin II arc contraction drive receptor cluster dynamics at the immunological synapse in Jurkat T cells. Mol Biol Cell (2012) 1.82
ATP-driven remodeling of the linker domain in the dynein motor. Structure (2012) 1.74
Linking molecular motors to membrane cargo. Curr Opin Cell Biol (2010) 1.73
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Step-size is determined by neck length in myosin V. Biochemistry (2005) 1.63
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Helix sliding in the stalk coiled coil of dynein couples ATPase and microtubule binding. Nat Struct Mol Biol (2009) 1.61
Functions and mechanics of dynein motor proteins. Nat Rev Mol Cell Biol (2013) 1.56
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Nanometer localization of single green fluorescent proteins: evidence that myosin V walks hand-over-hand via telemark configuration. Biophys J (2004) 1.50
Structures of smooth muscle myosin and heavy meromyosin in the folded, shutdown state. J Mol Biol (2007) 1.48
Myosin-Va transports the endoplasmic reticulum into the dendritic spines of Purkinje neurons. Nat Cell Biol (2010) 1.48
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Motor proteins at the microtubule plus-end. Trends Cell Biol (2006) 1.39
Rab10 and myosin-Va mediate insulin-stimulated GLUT4 storage vesicle translocation in adipocytes. J Cell Biol (2012) 1.38
Myosin Va facilitates the distribution of secretory granules in the F-actin rich cortex of PC12 cells. J Cell Sci (2003) 1.35
Myosin V from Drosophila reveals diversity of motor mechanisms within the myosin V family. J Biol Chem (2005) 1.32
A FERM domain autoregulates Drosophila myosin 7a activity. Proc Natl Acad Sci U S A (2009) 1.29
Nonmuscle myosin II exerts tension but does not translocate actin in vertebrate cytokinesis. Proc Natl Acad Sci U S A (2012) 1.29
The SAH domain extends the functional length of the myosin lever. Proc Natl Acad Sci U S A (2009) 1.29
Conservation of the regulated structure of folded myosin 2 in species separated by at least 600 million years of independent evolution. Proc Natl Acad Sci U S A (2008) 1.28
Kinetics of ADP dissociation from the trail and lead heads of actomyosin V following the power stroke. J Biol Chem (2007) 1.28
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Atlantoaxial transarticular screw fixation for a high-riding vertebral artery. Spine (Phila Pa 1976) (2003) 1.27
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Melanophilin and myosin Va track the microtubule plus end on EB1. J Cell Biol (2005) 1.22
Direct observation of the uncapping of capping protein-capped actin filaments by CARMIL homology domain 3. J Biol Chem (2009) 1.21
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MYH9-related disease: a novel prognostic model to predict the clinical evolution of the disease based on genotype-phenotype correlations. Hum Mutat (2013) 1.15
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Detection of a dural defect by cinematic magnetic resonance imaging and its selective closure as a treatment for a spinal extradural arachnoid cyst. Spine (Phila Pa 1976) (2004) 1.14
Mechanism of action of myosin X, a membrane-associated molecular motor. J Biol Chem (2005) 1.14
Subaxial subluxation after atlantoaxial transarticular screw fixation in rheumatoid patients. Eur Spine J (2009) 1.13
The binding of DYNLL2 to myosin Va requires alternatively spliced exon B and stabilizes a portion of the myosin's coiled-coil domain. Biochemistry (2006) 1.11
Non-muscle myosins 2A and 2B drive changes in cell morphology that occur as myoblasts align and fuse. J Cell Sci (2006) 1.11
Human myosin Vc is a low duty ratio, nonprocessive molecular motor. J Biol Chem (2008) 1.11
Myosin regulatory light chain (RLC) phosphorylation change as a modulator of cardiac muscle contraction in disease. J Biol Chem (2013) 1.10
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Myosin VI and its binding partner optineurin are involved in secretory vesicle fusion at the plasma membrane. Mol Biol Cell (2010) 1.09
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Kinetic mechanism of myosinV-S1 using a new fluorescent ATP analogue. Biochemistry (2006) 1.06
Gamma-aminobutyric acid as a promoting factor of cancer metastasis; induction of matrix metalloproteinase production is potentially its underlying mechanism. Cancer Res (2003) 1.06
Folding and regulation in myosins II and V. J Muscle Res Cell Motil (2008) 1.06
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Delayed postoperative spinal epidural hematoma causing tetraplegia. Case report. J Neurosurg Spine (2006) 1.04
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Switch 1 mutation S217A converts myosin V into a low duty ratio motor. J Biol Chem (2008) 1.01
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dsu functions in a MYO5A-independent pathway to suppress the coat color of dilute mice. Proc Natl Acad Sci U S A (2004) 1.00
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CARMIL is a bona fide capping protein interactant. J Biol Chem (2003) 0.99
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A safe screw trajectory for atlantoaxial transarticular fixation achieved using an aiming device. Spine (Phila Pa 1976) (2005) 0.98