Published in J Cell Biol on December 23, 2002
Video imaging of walking myosin V by high-speed atomic force microscopy. Nature (2010) 3.70
A force-dependent state controls the coordination of processive myosin V. Proc Natl Acad Sci U S A (2005) 2.39
Defocused orientation and position imaging (DOPI) of myosin V. Proc Natl Acad Sci U S A (2006) 2.27
The cargo-binding domain regulates structure and activity of myosin 5. Nature (2006) 2.03
Myosin-V is a mechanical ratchet. Proc Natl Acad Sci U S A (2006) 1.83
Myosin V motor proteins: marching stepwise towards a mechanism. J Cell Biol (2003) 1.63
Elastic lever-arm model for myosin V. Biophys J (2005) 1.62
Load-dependent ADP binding to myosins V and VI: implications for subunit coordination and function. Proc Natl Acad Sci U S A (2008) 1.61
Direct observation of the myosin Va recovery stroke that contributes to unidirectional stepping along actin. PLoS Biol (2011) 1.57
The motor mechanism of myosin V: insights for muscle contraction. Philos Trans R Soc Lond B Biol Sci (2004) 1.53
Direct observation of the mechanochemical coupling in myosin Va during processive movement. Nature (2008) 1.51
Nanometer localization of single green fluorescent proteins: evidence that myosin V walks hand-over-hand via telemark configuration. Biophys J (2004) 1.50
Adaptability of myosin V studied by simultaneous detection of position and orientation. EMBO J (2006) 1.40
A FERM domain autoregulates Drosophila myosin 7a activity. Proc Natl Acad Sci U S A (2009) 1.29
Cardiomyopathy mutations reveal variable region of myosin converter as major element of cross-bridge compliance. Biophys J (2009) 1.28
Direct observation of the myosin-Va power stroke and its reversal. Nat Struct Mol Biol (2010) 1.28
Load and Pi control flux through the branched kinetic cycle of myosin V. J Biol Chem (2008) 1.24
Unconstrained steps of myosin VI appear longest among known molecular motors. Biophys J (2004) 1.24
Dynamics of myosin-V processivity. Biophys J (2004) 1.16
Velocity, processivity, and individual steps of single myosin V molecules in live cells. Biophys J (2009) 1.15
High-speed AFM and nano-visualization of biomolecular processes. Pflugers Arch (2007) 1.14
Influence of lever structure on myosin 5a walking. Proc Natl Acad Sci U S A (2010) 1.05
Mechanochemical model for myosin V. Proc Natl Acad Sci U S A (2009) 0.97
Filming biomolecular processes by high-speed atomic force microscopy. Chem Rev (2014) 0.95
Myosin complexed with ADP and blebbistatin reversibly adopts a conformation resembling the start point of the working stroke. Proc Natl Acad Sci U S A (2010) 0.91
Mammalian myosin-18A, a highly divergent myosin. J Biol Chem (2013) 0.91
Structural dynamics of myosin 5 during processive motion revealed by interferometric scattering microscopy. Elife (2015) 0.88
Myosin-10 produces its power-stroke in two phases and moves processively along a single actin filament under low load. Proc Natl Acad Sci U S A (2014) 0.88
Switching of myosin-V motion between the lever-arm swing and brownian search-and-catch. Nat Commun (2012) 0.87
Calmodulin regulates dimerization, motility, and lipid binding of Leishmania myosin XXI. Proc Natl Acad Sci U S A (2013) 0.86
Myosin regulatory domain orientation in skeletal muscle fibers: application of novel electron paramagnetic resonance spectral decomposition and molecular modeling methods. Biophys J (2004) 0.85
Flexibility within the heads of muscle myosin-2 molecules. J Mol Biol (2013) 0.84
Calcium can mobilize and activate myosin-VI. Proc Natl Acad Sci U S A (2016) 0.84
Coarse-Grained Structural Modeling of Molecular Motors Using Multibody Dynamics. Cell Mol Bioeng (2009) 0.84
Similarities and differences between frozen-hydrated, rigor acto-S1 complexes of insect flight and chicken skeletal muscles. J Mol Biol (2008) 0.84
Nucleotide-dependent shape changes in the reverse direction motor, myosin VI. Biophys J (2010) 0.83
Visualization of human Bloom's syndrome helicase molecules bound to homologous recombination intermediates. FASEB J (2013) 0.82
Holding the reins on myosin V. Proc Natl Acad Sci U S A (2005) 0.81
A molecular dynamics study and free energy analysis of complexes between the Mlc1p protein and two IQ motif peptides. Biophys J (2006) 0.81
The lever arm effects a mechanical asymmetry of the myosin-V-actin bond. Biophys J (2010) 0.81
The kinetic mechanism of mouse myosin VIIA. J Biol Chem (2011) 0.78
Mechanical characterization of one-headed myosin-V using optical tweezers. PLoS One (2010) 0.77
Myosin V passing over Arp2/3 junctions: branching ratio calculated from the elastic lever arm model. Biophys J (2008) 0.77
The path to visualization of walking myosin V by high-speed atomic force microscopy. Biophys Rev (2014) 0.76
Myosin's mechanical ratchet. Proc Natl Acad Sci U S A (2006) 0.76
SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling. Electrophoresis (1997) 57.27
RASMOL: biomolecular graphics for all. Trends Biochem Sci (1995) 33.76
SPIDER and WEB: processing and visualization of images in 3D electron microscopy and related fields. J Struct Biol (1996) 22.89
Three-dimensional structure of myosin subfragment-1: a molecular motor. Science (1993) 14.90
The mechanism of muscular contraction. Science (1969) 14.47
Mechanism of adenosine triphosphate hydrolysis by actomyosin. Biochemistry (1971) 9.73
The way things move: looking under the hood of molecular motor proteins. Science (2000) 7.28
Myosin-V is a processive actin-based motor. Nature (1999) 7.13
A millennial myosin census. Mol Biol Cell (2001) 6.13
Structural mechanism of muscle contraction. Annu Rev Biochem (1999) 5.56
The gated gait of the processive molecular motor, myosin V. Nat Cell Biol (2002) 5.34
Myosin-V stepping kinetics: a molecular model for processivity. Proc Natl Acad Sci U S A (2000) 5.03
X-ray structures of the myosin motor domain of Dictyostelium discoideum complexed with MgADP.BeFx and MgADP.AlF4-. Biochemistry (1995) 4.64
The kinetic mechanism of myosin V. Proc Natl Acad Sci U S A (1999) 4.56
X-ray structure of the magnesium(II).ADP.vanadate complex of the Dictyostelium discoideum myosin motor domain to 1.9 A resolution. Biochemistry (1996) 4.32
A 35-A movement of smooth muscle myosin on ADP release. Nature (1995) 4.28
Refinement of the F-actin model against X-ray fiber diffraction data by the use of a directed mutation algorithm. J Mol Biol (1993) 3.80
Two-headed binding of a processive myosin to F-actin. Nature (2000) 3.73
The ribosome at improved resolution: new techniques for merging and orientation refinement in 3D cryo-electron microscopy of biological particles. Ultramicroscopy (1994) 3.68
The neck region of the myosin motor domain acts as a lever arm to generate movement. Proc Natl Acad Sci U S A (1996) 3.61
Molecular motors: structural adaptations to cellular functions. Nature (1997) 3.57
Three conformational states of scallop myosin S1. Proc Natl Acad Sci U S A (2000) 3.06
Atomic structure of scallop myosin subfragment S1 complexed with MgADP: a novel conformation of the myosin head. Cell (1999) 2.99
The motor protein myosin-I produces its working stroke in two steps. Nature (1999) 2.95
Kinetic mechanism and regulation of myosin VI. J Biol Chem (2001) 2.93
A 32 degree tail swing in brush border myosin I on ADP release. Nature (1995) 2.73
Primary structure and cellular localization of chicken brain myosin-V (p190), an unconventional myosin with calmodulin light chains. J Cell Biol (1992) 2.73
Class V myosins. Biochim Biophys Acta (2000) 2.62
Structure of the regulatory domain of scallop myosin at 2 A resolution: implications for regulation. Structure (1996) 2.45
Effect of ADP and ionic strength on the kinetic and motile properties of recombinant mouse myosin V. J Biol Chem (2000) 2.09
X-ray structures of the MgADP, MgATPgammaS, and MgAMPPNP complexes of the Dictyostelium discoideum myosin motor domain. Biochemistry (1997) 2.08
Class VI myosin moves processively along actin filaments backward with large steps. Biochem Biophys Res Commun (2002) 2.01
Myosin motors: missing structures and hidden springs. Curr Opin Struct Biol (2001) 1.98
Evidence for cleft closure in actomyosin upon ADP release. Nat Struct Biol (2000) 1.97
Is myosin a "back door" enzyme? Biophys J (1995) 1.96
Myosin V exhibits a high duty cycle and large unitary displacement. J Cell Biol (2001) 1.95
Structure of the myosin projections on native thick filaments from vertebrate skeletal muscle. J Mol Biol (1984) 1.88
A FRET-based sensor reveals large ATP hydrolysis-induced conformational changes and three distinct states of the molecular motor myosin. Cell (2000) 1.75
Resolution of conformational states of Dictyostelium myosin II motor domain using tryptophan (W501) mutants: implications for the open-closed transition identified by crystallography. Biochemistry (2000) 1.73
X-ray structures of the apo and MgATP-bound states of Dictyostelium discoideum myosin motor domain. J Biol Chem (2000) 1.59
Single-molecule tracking of myosins with genetically engineered amplifier domains. Nat Struct Biol (2001) 1.58
Kinetic characterization of the weak binding states of myosin V. Biochemistry (2002) 1.46
Negative staining of myosin molecules. J Mol Biol (1985) 1.45
The structure of the acto-myosin subfragment 1 complex: results of searches using data from electron microscopy and x-ray crystallography. Proc Natl Acad Sci U S A (1997) 1.44
A fluorescence temperature-jump study of conformational transitions in myosin subfragment 1. Biochem J (2001) 1.05
Single molecule analysis of the actomyosin motor. Curr Opin Cell Biol (2000) 1.05
A myosin family reunion. J Muscle Res Cell Motil (1996) 0.98
Flexibility within myosin heads revealed by negative stain and single-particle analysis. J Cell Biol (1997) 0.96
Phosphorylation regulates the ADP-induced rotation of the light chain domain of smooth muscle myosin. Biochemistry (1999) 0.93
Dissecting temporal and spatial control of cytokinesis with a myosin II Inhibitor. Science (2003) 12.41
Divergent signals and cytoskeletal assemblies regulate self-organizing polarity in neutrophils. Cell (2003) 6.46
Mechanism of blebbistatin inhibition of myosin II. J Biol Chem (2004) 5.45
The gated gait of the processive molecular motor, myosin V. Nat Cell Biol (2002) 5.34
SIRT3, a mitochondrial sirtuin deacetylase, regulates mitochondrial function and thermogenesis in brown adipocytes. J Biol Chem (2005) 4.80
Dynein structure and power stroke. Nature (2003) 4.25
Electrical signals control wound healing through phosphatidylinositol-3-OH kinase-gamma and PTEN. Nature (2006) 4.09
Identification of an organelle receptor for myosin-Va. Nat Cell Biol (2002) 4.06
Rac and Cdc42 play distinct roles in regulating PI(3,4,5)P3 and polarity during neutrophil chemotaxis. J Cell Biol (2003) 4.02
A mathematical treatment of integrated Ca dynamics within the ventricular myocyte. Biophys J (2004) 3.72
Load-dependent kinetics of myosin-V can explain its high processivity. Nat Cell Biol (2005) 3.69
Material properties of the cell dictate stress-induced spreading and differentiation in embryonic stem cells. Nat Mater (2009) 3.30
Myosin-XVa is required for tip localization of whirlin and differential elongation of hair-cell stereocilia. Nat Cell Biol (2005) 3.15
Identification and characterization of nonmuscle myosin II-C, a new member of the myosin II family. J Biol Chem (2003) 2.98
Specificity of blebbistatin, an inhibitor of myosin II. J Muscle Res Cell Motil (2004) 2.96
Polarity and proliferation are controlled by distinct signaling pathways downstream of PI3-kinase in breast epithelial tumor cells. J Cell Biol (2004) 2.93
Calculation of risk of colorectal and endometrial cancer among patients with Lynch syndrome. Gastroenterology (2009) 2.75
AAA+ Ring and linker swing mechanism in the dynein motor. Cell (2009) 2.63
Disparities in diabetes care: impact of mental illness. Arch Intern Med (2005) 2.45
Selection of reliable reference genes for gene expression studies in peach using real-time PCR. BMC Mol Biol (2009) 2.35
Structures and receptor binding of hemagglutinins from human-infecting H7N9 influenza viruses. Science (2013) 2.34
Risk of pancreatic cancer in families with Lynch syndrome. JAMA (2009) 2.32
China's life satisfaction, 1990-2010. Proc Natl Acad Sci U S A (2012) 2.31
Blebbistatin, a myosin II inhibitor, is photoinactivated by blue light. Biochemistry (2005) 2.29
Approximate model of cooperative activation and crossbridge cycling in cardiac muscle using ordinary differential equations. Biophys J (2008) 2.29
Neck length and processivity of myosin V. J Biol Chem (2003) 2.23
Kinetic mechanism of non-muscle myosin IIB: functional adaptations for tension generation and maintenance. J Biol Chem (2003) 2.19
Titin: properties and family relationships. Nat Rev Mol Cell Biol (2003) 2.18
The predicted coiled-coil domain of myosin 10 forms a novel elongated domain that lengthens the head. J Biol Chem (2005) 2.11
The effects of statins and renin-angiotensin system blockers on atrial fibrillation recurrence following antral pulmonary vein isolation. J Cardiovasc Electrophysiol (2007) 2.09
The cargo-binding domain regulates structure and activity of myosin 5. Nature (2006) 2.03
Functional divergence of human cytoplasmic myosin II: kinetic characterization of the non-muscle IIA isoform. J Biol Chem (2003) 2.03
Medial patella retinaculum plasty for treatment of habitual patellar dislocation in adolescents. Int Orthop (2012) 2.02
Residual risk of transfusion-transmitted viral infections in Shenzhen, China, 2001 through 2004. Transfusion (2007) 1.99
Load-dependent mechanism of nonmuscle myosin 2. Proc Natl Acad Sci U S A (2007) 1.97
Isolation of phosphatidylethanolamine as a solitary cofactor for prion formation in the absence of nucleic acids. Proc Natl Acad Sci U S A (2012) 1.97
Cryo-electron microscopy of the vacuolar ATPase motor reveals its mechanical and regulatory complexity. J Mol Biol (2009) 1.96
Walking to work: roles for class V myosins as cargo transporters. Nat Rev Mol Cell Biol (2011) 1.93
Regulated conformation of myosin V. J Biol Chem (2003) 1.90
Rab27a is an essential component of melanosome receptor for myosin Va. Mol Biol Cell (2002) 1.89
Disease-associated mutations and alternative splicing alter the enzymatic and motile activity of nonmuscle myosins II-B and II-C. J Biol Chem (2005) 1.86
The status of glycemic control: A cross-sectional study of outpatients with type 2 diabetes mellitus across primary, secondary, and tertiary hospitals in the Jiangsu province of China. Clin Ther (2010) 1.83
Hepatocyte growth factor switches orientation of polarity and mode of movement during morphogenesis of multicellular epithelial structures. Mol Biol Cell (2003) 1.82
Neutrophil microtubules suppress polarity and enhance directional migration. Proc Natl Acad Sci U S A (2005) 1.81
Cofactor molecules maintain infectious conformation and restrict strain properties in purified prions. Proc Natl Acad Sci U S A (2012) 1.77
A monomeric myosin VI with a large working stroke. EMBO J (2004) 1.75
ATP-driven remodeling of the linker domain in the dynein motor. Structure (2012) 1.74
Use of negative stain and single-particle image processing to explore dynamic properties of flexible macromolecules. J Struct Biol (2004) 1.71
Hypertensive patients' race, health beliefs, process of care, and medication adherence. J Gen Intern Med (2007) 1.69
Structural basis for tail-anchored membrane protein biogenesis by the Get3-receptor complex. Science (2011) 1.68
The fat mass and obesity associated gene FTO functions in the brain to regulate postnatal growth in mice. PLoS One (2010) 1.67
Rare ADH variant constellations are specific for alcohol dependence. Alcohol Alcohol (2012) 1.66
NAMPT is essential for the G-CSF-induced myeloid differentiation via a NAD(+)-sirtuin-1-dependent pathway. Nat Med (2009) 1.66
mTOR supports long-term self-renewal and suppresses mesoderm and endoderm activities of human embryonic stem cells. Proc Natl Acad Sci U S A (2009) 1.63
Step-size is determined by neck length in myosin V. Biochemistry (2005) 1.63
Helix sliding in the stalk coiled coil of dynein couples ATPase and microtubule binding. Nat Struct Mol Biol (2009) 1.61
High-efficiency induction of neural conversion in human ESCs and human induced pluripotent stem cells with a single chemical inhibitor of transforming growth factor beta superfamily receptors. Stem Cells (2010) 1.61
Asymmetry analysis of cingulum based on scale-invariant parameterization by diffusion tensor imaging. Hum Brain Mapp (2005) 1.58
Functions and mechanics of dynein motor proteins. Nat Rev Mol Cell Biol (2013) 1.56
Single-port and multi-port laparoscopic left lateral liver sectionectomy for treating benign liver diseases: a prospective, randomized, controlled study. World J Surg (2014) 1.54
Bound attractant at the leading vs. the trailing edge determines chemotactic prowess. Proc Natl Acad Sci U S A (2007) 1.54
Using administrative data to identify mental illness: what approach is best? Am J Med Qual (2009) 1.54
Direct observation of the mechanochemical coupling in myosin Va during processive movement. Nature (2008) 1.51
Nanometer localization of single green fluorescent proteins: evidence that myosin V walks hand-over-hand via telemark configuration. Biophys J (2004) 1.50
Genome-wide association study of alcohol dependence implicates KIAA0040 on chromosome 1q. Neuropsychopharmacology (2011) 1.50
A critical role of autophagy in plant resistance to necrotrophic fungal pathogens. Plant J (2011) 1.49
Changes and their prognostic implications in the abbreviated VitalPAC™ Early Warning Score (ViEWS) after admission to hospital of 18,827 surgical patients. Resuscitation (2012) 1.49
Substrate binding disrupts dimerization and induces nucleotide exchange of the chloroplast GTPase Toc33. Biochem J (2011) 1.49
Abnormal anterior cingulum in patients with schizophrenia: a diffusion tensor imaging study. Neuroreport (2003) 1.49
Structural divergence of the rotary ATPases. Q Rev Biophys (2011) 1.48
Structures of smooth muscle myosin and heavy meromyosin in the folded, shutdown state. J Mol Biol (2007) 1.48
Elevated levels of oxidized low-density lipoprotein correlate positively with C-reactive protein in patients with acute coronary syndrome. Cell Biochem Biophys (2012) 1.47
Regulation of cardiac sarcoplasmic reticulum Ca release by luminal [Ca] and altered gating assessed with a mathematical model. Biophys J (2005) 1.47
Preliminary evidence for persistent abnormalities in amygdala volumes in adolescents and young adults with bipolar disorder. Bipolar Disord (2005) 1.47
The F-box protein AhSLF-S2 controls the pollen function of S-RNase-based self-incompatibility. Plant Cell (2004) 1.47
Combining knowledge and data driven insights for identifying risk factors using electronic health records. AMIA Annu Symp Proc (2012) 1.46
miR-124 inhibits STAT3 signaling to enhance T cell-mediated immune clearance of glioma. Cancer Res (2013) 1.46
Human anti-anthrax protective antigen neutralizing monoclonal antibodies derived from donors vaccinated with anthrax vaccine adsorbed. J Immune Based Ther Vaccines (2004) 1.46
Retracted Relationships between PTEN gene mutations and prognosis in glioma: a meta-analysis. Tumour Biol (2014) 1.45
atToc159 is a selective transit peptide receptor for the import of nucleus-encoded chloroplast proteins. J Cell Biol (2004) 1.45
Mutations in human nonmuscle myosin IIA found in patients with May-Hegglin anomaly and Fechtner syndrome result in impaired enzymatic function. J Biol Chem (2002) 1.44
[Responses of spatial distribution pattern of Artemisia ordosica population to the precipitation gradient on Ordos Plateau]. Ying Yong Sheng Tai Xue Bao (2009) 1.44
Changes and their prognostic implications in the abbreviated Vitalpac™ early warning score (ViEWS) after admission to hospital of 18,853 acutely ill medical patients. Resuscitation (2012) 1.43
Arabidopsis sigma factor binding proteins are activators of the WRKY33 transcription factor in plant defense. Plant Cell (2011) 1.43
Development of an automatic subsea blowout preventer stack control system using PLC based SCADA. ISA Trans (2011) 1.40
Paired-angle-rotation scanning optical coherence tomography forward-imaging probe. Opt Lett (2006) 1.39
An update on recent advances in asthma management. Conn Med (2008) 1.39