Published in Curr Biol on January 19, 2012
Characterization of the transcriptome of nascent hair cells and identification of direct targets of the Atoh1 transcription factor. J Neurosci (2015) 0.95
FCHSD1 and FCHSD2 are expressed in hair cell stereocilia and cuticular plate and regulate actin polymerization in vitro. PLoS One (2013) 0.91
Myosin 3A kinase activity is regulated by phosphorylation of the kinase domain activation loop. J Biol Chem (2013) 0.90
Competition and compensation: dissecting the biophysical and functional differences between the class 3 myosin paralogs, myosins 3a and 3b. Bioarchitecture (2012) 0.87
Invertebrate and vertebrate class III myosins interact with MORN repeat-containing adaptor proteins. PLoS One (2015) 0.85
Characterization and regulation of an additional actin-filament-binding site in large isoforms of the stereocilia actin-bundling protein espin. J Cell Sci (2014) 0.85
Assembly of hair bundles, an amazing problem for cell biology. Mol Biol Cell (2015) 0.83
Various Themes of Myosin Regulation. J Mol Biol (2016) 0.83
Class III myosins shape the auditory hair bundles by limiting microvilli and stereocilia growth. J Cell Biol (2016) 0.83
Kinetic Adaptations of Myosins for Their Diverse Cellular Functions. Traffic (2016) 0.79
MYO3A Causes Human Dominant Deafness and Interacts with Protocadherin 15-CD2 Isoform. Hum Mutat (2016) 0.79
Genetics of auditory mechano-electrical transduction. Pflugers Arch (2014) 0.79
Stereocilia-staircase spacing is influenced by myosin III motors and their cargos espin-1 and espin-like. Nat Commun (2016) 0.78
A single-headed fission yeast myosin V transports actin in a tropomyosin-dependent manner. J Cell Biol (2016) 0.77
Myosin III-mediated cross-linking and stimulation of actin bundling activity of Espin. Elife (2016) 0.77
Myosin-7b Promotes Distal Tip Localization of the Intermicrovillar Adhesion Complex. Curr Biol (2016) 0.76
My oh my(osin): Insights into how auditory hair cells count, measure, and shape. J Cell Biol (2016) 0.75
Plastin 1 widens stereocilia by transforming actin filament packing from hexagonal to liquid. J Cell Biol (2016) 0.75
Initial sites of hepadnavirus integration into host genome in human hepatocytes and in the woodchuck model of hepatitis B-associated hepatocellular carcinoma. Oncogenesis (2017) 0.75
Impact of the Motor and Tail Domains of Class III Myosins on Regulating the Formation and Elongation of Actin Protrusions. J Biol Chem (2016) 0.75
Dynactin increases the processivity of the cytoplasmic dynein motor. Nat Cell Biol (2000) 6.13
Drosophila Spire is an actin nucleation factor. Nature (2005) 3.64
Review series: The cell biology of hearing. J Cell Biol (2010) 2.29
Stepwise morphological and functional maturation of mechanotransduction in rat outer hair cells. J Neurosci (2007) 2.28
From flies' eyes to our ears: mutations in a human class III myosin cause progressive nonsyndromic hearing loss DFNB30. Proc Natl Acad Sci U S A (2002) 2.17
The cargo-binding domain regulates structure and activity of myosin 5. Nature (2006) 2.03
Myosin IIIa boosts elongation of stereocilia by transporting espin 1 to the plus ends of actin filaments. Nat Cell Biol (2009) 1.83
A new compartment at stereocilia tips defined by spatial and temporal patterns of myosin IIIa expression. J Neurosci (2006) 1.73
Mammalian Kinesin-3 motors are dimeric in vivo and move by processive motility upon release of autoinhibition. PLoS Biol (2009) 1.66
Dynamic length regulation of sensory stereocilia. Semin Cell Dev Biol (2008) 1.54
A novel form of motility in filopodia revealed by imaging myosin-X at the single-molecule level. Curr Biol (2009) 1.53
Direct observation of the mechanochemical coupling in myosin Va during processive movement. Nature (2008) 1.51
When size matters: the dynamic regulation of stereocilia lengths. Curr Opin Cell Biol (2005) 1.36
Cargo binding induces dimerization of myosin VI. Proc Natl Acad Sci U S A (2009) 1.34
Phospholipid-dependent regulation of the motor activity of myosin X. Nat Struct Mol Biol (2011) 1.30
Calcium functionally uncouples the heads of myosin VI. J Biol Chem (2003) 1.18
Protein localization by actin treadmilling and molecular motors regulates stereocilia shape and treadmilling rate. Biophys J (2008) 1.17
Myo3A, one of two class III myosin genes expressed in vertebrate retina, is localized to the calycal processes of rod and cone photoreceptors and is expressed in the sacculus. Mol Biol Cell (2003) 1.14
Localization of a class III myosin to filopodia tips in transfected HeLa cells requires an actin-binding site in its tail domain. Mol Biol Cell (2003) 1.10
Kinetic mechanism of human myosin IIIA. J Biol Chem (2006) 1.08
Cargo binding activates myosin VIIA motor function in cells. Proc Natl Acad Sci U S A (2011) 1.07
Intermolecular autophosphorylation regulates myosin IIIa activity and localization in parallel actin bundles. J Biol Chem (2010) 1.03
The kinase domain alters the kinetic properties of the myosin IIIA motor. Biochemistry (2008) 1.02
Targeted wild-type and jerker espins reveal a novel, WH2-domain-dependent way to make actin bundles in cells. J Cell Sci (2006) 1.01
A mouse model for human hearing loss DFNB30 due to loss of function of myosin IIIA. Mamm Genome (2010) 0.96
Functional adaptation of the switch-2 nucleotide sensor enables rapid processive translocation by myosin-5. FASEB J (2010) 0.88
Cadherin 23 and protocadherin 15 interact to form tip-link filaments in sensory hair cells. Nature (2007) 4.87
Determination of elastic moduli of thin layers of soft material using the atomic force microscope. Biophys J (2002) 4.71
Otoferlin, defective in a human deafness form, is essential for exocytosis at the auditory ribbon synapse. Cell (2006) 3.71
A structural state of the myosin V motor without bound nucleotide. Nature (2003) 3.63
An actin molecular treadmill and myosins maintain stereocilia functional architecture and self-renewal. J Cell Biol (2004) 3.35
A role for actin arcs in the leading-edge advance of migrating cells. Nat Cell Biol (2011) 2.68
The structure of the myosin VI motor reveals the mechanism of directionality reversal. Nature (2005) 2.50
Review series: The cell biology of hearing. J Cell Biol (2010) 2.29
Stepwise morphological and functional maturation of mechanotransduction in rat outer hair cells. J Neurosci (2007) 2.28
Rapid renewal of auditory hair bundles. Nature (2002) 2.28
Mutations in Mcoln3 associated with deafness and pigmentation defects in varitint-waddler (Va) mice. Proc Natl Acad Sci U S A (2002) 2.03
Role of membrane proteins in permeability barrier function: uroplakin ablation elevates urothelial permeability. Am J Physiol Renal Physiol (2002) 1.91
Deafness in Claudin 11-null mice reveals the critical contribution of basal cell tight junctions to stria vascularis function. J Neurosci (2004) 1.86
Myosin IIIa boosts elongation of stereocilia by transporting espin 1 to the plus ends of actin filaments. Nat Cell Biol (2009) 1.83
A new compartment at stereocilia tips defined by spatial and temporal patterns of myosin IIIa expression. J Neurosci (2006) 1.73
Roles of uroplakins in plaque formation, umbrella cell enlargement, and urinary tract diseases. J Cell Biol (2004) 1.69
Bleaching/blinking assisted localization microscopy for superresolution imaging using standard fluorescent molecules. Proc Natl Acad Sci U S A (2011) 1.69
Harmonin mutations cause mechanotransduction defects in cochlear hair cells. Neuron (2009) 1.63
Myosin VIIa and sans localization at stereocilia upper tip-link density implicates these Usher syndrome proteins in mechanotransduction. Proc Natl Acad Sci U S A (2011) 1.62
Complete exon sequencing of all known Usher syndrome genes greatly improves molecular diagnosis. Orphanet J Rare Dis (2011) 1.57
Regulation of stereocilia length by myosin XVa and whirlin depends on the actin-regulatory protein Eps8. Curr Biol (2011) 1.55
Dynamic length regulation of sensory stereocilia. Semin Cell Dev Biol (2008) 1.54
A novel form of motility in filopodia revealed by imaging myosin-X at the single-molecule level. Curr Biol (2009) 1.53
Balanced levels of Espin are critical for stereociliary growth and length maintenance. Cell Motil Cytoskeleton (2005) 1.47
Rapid turnover of stereocilia membrane proteins: evidence from the trafficking and mobility of plasma membrane Ca(2+)-ATPase 2. J Neurosci (2006) 1.47
Distinct subdomain organization and molecular composition of a tight junction with adherens junction features. J Cell Sci (2006) 1.45
Mouse models of MYH9-related disease: mutations in nonmuscle myosin II-A. Blood (2011) 1.41
Kinetic mechanism of blebbistatin inhibition of nonmuscle myosin IIb. Biochemistry (2004) 1.40
A mouse model for nonsyndromic deafness (DFNB12) links hearing loss to defects in tip links of mechanosensory hair cells. Proc Natl Acad Sci U S A (2009) 1.39
Cutting edge: CD4 is the receptor for the tick saliva immunosuppressor, Salp15. J Immunol (2006) 1.39
When size matters: the dynamic regulation of stereocilia lengths. Curr Opin Cell Biol (2005) 1.36
Evidence and implications of inhomogeneity in tectorial membrane elasticity. Biophys J (2004) 1.36
Retinal parallel processors: more than 100 independent microcircuits operate within a single interneuron. Neuron (2010) 1.33
Sharp Ca²⁺ nanodomains beneath the ribbon promote highly synchronous multivesicular release at hair cell synapses. J Neurosci (2011) 1.33
Differential expression of KCNQ4 in inner hair cells and sensory neurons is the basis of progressive high-frequency hearing loss. J Neurosci (2005) 1.32
NMII forms a contractile transcellular sarcomeric network to regulate apical cell junctions and tissue geometry. Curr Biol (2013) 1.29
Localization and functional studies of pendrin in the mouse inner ear provide insight about the etiology of deafness in pendred syndrome. J Assoc Res Otolaryngol (2003) 1.27
Regulation of PCDH15 function in mechanosensory hair cells by alternative splicing of the cytoplasmic domain. Development (2011) 1.27
Dynamic compartmentalization of protein tyrosine phosphatase receptor Q at the proximal end of stereocilia: implication of myosin VI-based transport. Cell Motil Cytoskeleton (2008) 1.26
Expression of prestin, a membrane motor protein, in the mammalian auditory and vestibular periphery. Hear Res (2003) 1.24
SAP102 is a highly mobile MAGUK in spines. J Neurosci (2010) 1.22
Protein localization by actin treadmilling and molecular motors regulates stereocilia shape and treadmilling rate. Biophys J (2008) 1.17
Mutation of the ATP-gated P2X(2) receptor leads to progressive hearing loss and increased susceptibility to noise. Proc Natl Acad Sci U S A (2013) 1.12
Tip links in hair cells: molecular composition and role in hearing loss. Curr Opin Otolaryngol Head Neck Surg (2009) 1.11
Localization of a class III myosin to filopodia tips in transfected HeLa cells requires an actin-binding site in its tail domain. Mol Biol Cell (2003) 1.10
CLAMP, a novel microtubule-associated protein with EB-type calponin homology. Cell Motil Cytoskeleton (2005) 1.09
Integrating the biophysical and molecular mechanisms of auditory hair cell mechanotransduction. Nat Commun (2011) 1.08
Kinetic mechanism of human myosin IIIA. J Biol Chem (2006) 1.08
Cdc42 and ARP2/3-independent regulation of filopodia by an integral membrane lipid-phosphatase-related protein. J Cell Sci (2007) 1.06
Differential expression of genes within the cochlea as defined by a custom mouse inner ear microarray. J Assoc Res Otolaryngol (2005) 1.06
Have we found the tip link, transduction channel, and gating spring of the hair cell? Curr Opin Neurobiol (2005) 1.05
Localization of PDZD7 to the stereocilia ankle-link associates this scaffolding protein with the Usher syndrome protein network. J Neurosci (2012) 1.05
Sustained cadherin 23 expression in young and adult cochlea of normal and hearing-impaired mice. Hear Res (2005) 1.05
A novel bovine virus efficiently transduces inner ear neuroepithelial cells. Mol Ther (2005) 1.05
T-cell signaling pathways inhibited by the tick saliva immunosuppressor, Salp15. FEMS Immunol Med Microbiol (2007) 1.04
Exome sequencing identifies a missense mutation in Isl1 associated with low penetrance otitis media in dearisch mice. Genome Biol (2011) 1.03
Intermolecular autophosphorylation regulates myosin IIIa activity and localization in parallel actin bundles. J Biol Chem (2010) 1.03
The kinase domain alters the kinetic properties of the myosin IIIA motor. Biochemistry (2008) 1.02
Roles of alternative splicing in the functional properties of inner ear-specific KCNQ4 channels. J Biol Chem (2007) 1.02
Dynamics of the upper 50-kDa domain of myosin V examined with fluorescence resonance energy transfer. J Biol Chem (2005) 1.02
Sensorimotor function as a predictor of chronic ankle instability. Clin Biomech (Bristol, Avon) (2009) 1.01
Progressive hearing loss and gradual deterioration of sensory hair bundles in the ears of mice lacking the actin-binding protein Eps8L2. Proc Natl Acad Sci U S A (2013) 0.99
Regulation of outer hair cell cytoskeletal stiffness by intracellular Ca2+: underlying mechanism and implications for cochlear mechanics. Cell Calcium (2003) 0.98
Kinetics and thermodynamics of the rate-limiting conformational change in the actomyosin V mechanochemical cycle. J Mol Biol (2011) 0.96
Changes in plasma membrane structure and electromotile properties in prestin deficient outer hair cells. Cytoskeleton (Hoboken) (2010) 0.95
Developmental expression of Kcnq4 in vestibular neurons and neurosensory epithelia. Brain Res (2007) 0.95
New source of muscle-derived stem cells with potential for alveolar bone reconstruction in cleft lip and/or palate patients. Tissue Eng Part A (2009) 0.93
Characterization of the pre-force-generation state in the actomyosin cross-bridge cycle. Proc Natl Acad Sci U S A (2008) 0.93
Mechanisms of hearing loss after blast injury to the ear. PLoS One (2013) 0.92
Switch II mutants reveal coupling between the nucleotide- and actin-binding regions in myosin V. Biophys J (2012) 0.91
Swept field laser confocal microscopy for enhanced spatial and temporal resolution in live-cell imaging. Microsc Microanal (2012) 0.91
Regulation of cellular calcium in vestibular supporting cells by otopetrin 1. J Neurophysiol (2010) 0.91
Myosin 3A kinase activity is regulated by phosphorylation of the kinase domain activation loop. J Biol Chem (2013) 0.90
Identification of unique transcripts from a mouse full-length, subtracted inner ear cDNA library. Genomics (2004) 0.90
Gene expression profile of the mouse organ of Corti at the onset of hearing. Genomics (2004) 0.88
In vivo rescue of alveolar macrophages from SP-A knockout mice with exogenous SP-A nearly restores a wild type intracellular proteome; actin involvement. Proteome Sci (2011) 0.88
Immunogold TEM of otoconin 90 and otolin - relevance to mineralization of otoconia, and pathogenesis of benign positional vertigo. Hear Res (2012) 0.87
Correlation of actin crosslinker and capper expression levels with stereocilia growth phases. Mol Cell Proteomics (2013) 0.87
Human deafness mutation E385D disrupts the mechanochemical coupling and subcellular targeting of myosin-1a. Biophys J (2007) 0.86
The mechanotransduction machinery of hair cells. Sci Signal (2009) 0.86
Whirlin, a cytoskeletal scaffolding protein, stabilizes the paranodal region and axonal cytoskeleton in myelinated axons. BMC Neurosci (2013) 0.86