Published in Proc Natl Acad Sci U S A on January 25, 2010
Video imaging of walking myosin V by high-speed atomic force microscopy. Nature (2010) 3.70
Two single-headed myosin V motors bound to a tetrameric adapter protein form a processive complex. J Cell Biol (2011) 1.03
Tilting and wobble of myosin V by high-speed single-molecule polarized fluorescence microscopy. Biophys J (2013) 1.01
Visualizing key hinges and a potential major source of compliance in the lever arm of myosin. Proc Natl Acad Sci U S A (2010) 0.96
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Filming biomolecular processes by high-speed atomic force microscopy. Chem Rev (2014) 0.95
Structural dynamics of myosin 5 during processive motion revealed by interferometric scattering microscopy. Elife (2015) 0.88
Switching of myosin-V motion between the lever-arm swing and brownian search-and-catch. Nat Commun (2012) 0.87
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Lever-arm mechanics of processive myosins. Biophys J (2011) 0.85
The azimuthal path of myosin V and its dependence on lever-arm length. J Gen Physiol (2012) 0.83
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Dwell time distributions of the molecular motor myosin V. PLoS One (2013) 0.75
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The gated gait of the processive molecular motor, myosin V. Nat Cell Biol (2002) 5.34
Brain myosin-V is a two-headed unconventional myosin with motor activity. Cell (1993) 5.24
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Movement and force produced by a single myosin head. Nature (1995) 4.92
Three-dimensional structural dynamics of myosin V by single-molecule fluorescence polarization. Nature (2003) 4.52
Two-headed binding of a processive myosin to F-actin. Nature (2000) 3.73
Load-dependent kinetics of myosin-V can explain its high processivity. Nat Cell Biol (2005) 3.69
F-actin is a helix with a random variable twist. Nature (1982) 3.32
New insights into myosin evolution and classification. Proc Natl Acad Sci U S A (2006) 2.97
Role of the lever arm in the processive stepping of myosin V. Proc Natl Acad Sci U S A (2002) 2.86
Computer averaging of electron micrographs of 40S ribosomal subunits. Science (1981) 2.79
Drawing the tree of eukaryotic life based on the analysis of 2,269 manually annotated myosins from 328 species. Genome Biol (2007) 2.53
A model of myosin V processivity. J Biol Chem (2004) 2.49
The stiffness of rabbit skeletal actomyosin cross-bridges determined with an optical tweezers transducer. Biophys J (1998) 2.32
Neck length and processivity of myosin V. J Biol Chem (2003) 2.23
Skeletal muscle performance determined by modulation of number of myosin motors rather than motor force or stroke size. Cell (2007) 2.19
The prepower stroke conformation of myosin V. J Cell Biol (2002) 2.12
Effect of ADP and ionic strength on the kinetic and motile properties of recombinant mouse myosin V. J Biol Chem (2000) 2.09
Dynamics of the unbound head during myosin V processive translocation. Nat Struct Mol Biol (2007) 2.04
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The structural basis of myosin V processive movement as revealed by electron cryomicroscopy. Mol Cell (2005) 1.82
Monoclonal antibodies localize changes on myosin heavy chain isozymes during avian myogenesis. Cell (1983) 1.65
Electron microscopy of thin filaments decorated with a Ca2+-regulated myosin. J Mol Biol (1980) 1.64
Step-size is determined by neck length in myosin V. Biochemistry (2005) 1.63
Kinetic characterization of the weak binding states of myosin V. Biochemistry (2002) 1.46
Negative staining of myosin molecules. J Mol Biol (1985) 1.45
Actin and light chain isoform dependence of myosin V kinetics. Biochemistry (2000) 1.45
Kinetics of ADP dissociation from the trail and lead heads of actomyosin V following the power stroke. J Biol Chem (2007) 1.28
High-speed AFM and nano-visualization of biomolecular processes. Pflugers Arch (2007) 1.14
Single-molecule measurement of the stiffness of the rigor myosin head. Biophys J (2007) 1.11
Kinetic mechanism of myosinV-S1 using a new fluorescent ATP analogue. Biochemistry (2006) 1.06
Myosin V stepping mechanism. Proc Natl Acad Sci U S A (2007) 1.01
Influence of fluctuations in actin structure on myosin V step size. J Chem Inf Model (2005) 0.90
Preparation of N-ethylmaleimide-modified heavy meromyosin and its use as a functional probe of actomyosin-based motility. Methods Enzymol (1986) 0.84
Dissecting temporal and spatial control of cytokinesis with a myosin II Inhibitor. Science (2003) 12.41
Mechanism of blebbistatin inhibition of myosin II. J Biol Chem (2004) 5.45
The gated gait of the processive molecular motor, myosin V. Nat Cell Biol (2002) 5.34
Dynein structure and power stroke. Nature (2003) 4.25
Identification of an organelle receptor for myosin-Va. Nat Cell Biol (2002) 4.06
Load-dependent kinetics of myosin-V can explain its high processivity. Nat Cell Biol (2005) 3.69
Myosin-XVa is required for tip localization of whirlin and differential elongation of hair-cell stereocilia. Nat Cell Biol (2005) 3.15
Identification and characterization of nonmuscle myosin II-C, a new member of the myosin II family. J Biol Chem (2003) 2.98
Specificity of blebbistatin, an inhibitor of myosin II. J Muscle Res Cell Motil (2004) 2.96
AAA+ Ring and linker swing mechanism in the dynein motor. Cell (2009) 2.63
PRISMA-Equity 2012 extension: reporting guidelines for systematic reviews with a focus on health equity. PLoS Med (2012) 2.31
Blebbistatin, a myosin II inhibitor, is photoinactivated by blue light. Biochemistry (2005) 2.29
Neck length and processivity of myosin V. J Biol Chem (2003) 2.23
Effect of Smad7 expression on metastasis of mouse mammary carcinoma JygMC(A) cells. J Natl Cancer Inst (2005) 2.23
Kinetic mechanism of non-muscle myosin IIB: functional adaptations for tension generation and maintenance. J Biol Chem (2003) 2.19
Titin: properties and family relationships. Nat Rev Mol Cell Biol (2003) 2.18
The prepower stroke conformation of myosin V. J Cell Biol (2002) 2.12
The predicted coiled-coil domain of myosin 10 forms a novel elongated domain that lengthens the head. J Biol Chem (2005) 2.11
The cargo-binding domain regulates structure and activity of myosin 5. Nature (2006) 2.03
Functional divergence of human cytoplasmic myosin II: kinetic characterization of the non-muscle IIA isoform. J Biol Chem (2003) 2.03
Load-dependent mechanism of nonmuscle myosin 2. Proc Natl Acad Sci U S A (2007) 1.97
Cryo-electron microscopy of the vacuolar ATPase motor reveals its mechanical and regulatory complexity. J Mol Biol (2009) 1.96
Actin-bundling protein TRIOBP forms resilient rootlets of hair cell stereocilia essential for hearing. Cell (2010) 1.94
Walking to work: roles for class V myosins as cargo transporters. Nat Rev Mol Cell Biol (2011) 1.93
Regulated conformation of myosin V. J Biol Chem (2003) 1.90
Rab27a is an essential component of melanosome receptor for myosin Va. Mol Biol Cell (2002) 1.89
The clinical risk of vertebral artery injury from cervical pedicle screws inserted in degenerative vertebrae. Spine (Phila Pa 1976) (2005) 1.88
Disease-associated mutations and alternative splicing alter the enzymatic and motile activity of nonmuscle myosins II-B and II-C. J Biol Chem (2005) 1.86
A monomeric myosin VI with a large working stroke. EMBO J (2004) 1.75
ATP-driven remodeling of the linker domain in the dynein motor. Structure (2012) 1.74
Applying an equity lens to interventions: using PROGRESS ensures consideration of socially stratifying factors to illuminate inequities in health. J Clin Epidemiol (2013) 1.73
Use of negative stain and single-particle image processing to explore dynamic properties of flexible macromolecules. J Struct Biol (2004) 1.71
Step-size is determined by neck length in myosin V. Biochemistry (2005) 1.63
Helix sliding in the stalk coiled coil of dynein couples ATPase and microtubule binding. Nat Struct Mol Biol (2009) 1.61
Functions and mechanics of dynein motor proteins. Nat Rev Mol Cell Biol (2013) 1.56
Direct observation of the mechanochemical coupling in myosin Va during processive movement. Nature (2008) 1.51
Nanometer localization of single green fluorescent proteins: evidence that myosin V walks hand-over-hand via telemark configuration. Biophys J (2004) 1.50
Structural divergence of the rotary ATPases. Q Rev Biophys (2011) 1.48
Structures of smooth muscle myosin and heavy meromyosin in the folded, shutdown state. J Mol Biol (2007) 1.48
Mutations in human nonmuscle myosin IIA found in patients with May-Hegglin anomaly and Fechtner syndrome result in impaired enzymatic function. J Biol Chem (2002) 1.44
Polarized actin bundles formed by human fascin-1: their sliding and disassembly on myosin II and myosin V in vitro. J Neurochem (2003) 1.39
The structure of M.EcoKI Type I DNA methyltransferase with a DNA mimic antirestriction protein. Nucleic Acids Res (2008) 1.37
The effect of core destabilization on the mechanical resistance of I27. Biophys J (2002) 1.36
Myosin V from Drosophila reveals diversity of motor mechanisms within the myosin V family. J Biol Chem (2005) 1.32
Tumour specific promoter region methylation of the human homologue of the Drosophila Roundabout gene DUTT1 (ROBO1) in human cancers. Oncogene (2002) 1.31
A FERM domain autoregulates Drosophila myosin 7a activity. Proc Natl Acad Sci U S A (2009) 1.29
Nonmuscle myosin II exerts tension but does not translocate actin in vertebrate cytokinesis. Proc Natl Acad Sci U S A (2012) 1.29
The SAH domain extends the functional length of the myosin lever. Proc Natl Acad Sci U S A (2009) 1.29
Conservation of the regulated structure of folded myosin 2 in species separated by at least 600 million years of independent evolution. Proc Natl Acad Sci U S A (2008) 1.28
Kinetics of ADP dissociation from the trail and lead heads of actomyosin V following the power stroke. J Biol Chem (2007) 1.28
Mutation spectrum of MYO7A and evaluation of a novel nonsyndromic deafness DFNB2 allele with residual function. Hum Mutat (2008) 1.27
Atlantoaxial transarticular screw fixation for a high-riding vertebral artery. Spine (Phila Pa 1976) (2003) 1.27
Characterization of three full-length human nonmuscle myosin II paralogs. J Biol Chem (2013) 1.23
Myo4p is a monomeric myosin with motility uniquely adapted to transport mRNA. J Cell Biol (2007) 1.17
MYH9-related disease: a novel prognostic model to predict the clinical evolution of the disease based on genotype-phenotype correlations. Hum Mutat (2013) 1.15
Mechanism of action of myosin X, a membrane-associated molecular motor. J Biol Chem (2005) 1.14
Detection of a dural defect by cinematic magnetic resonance imaging and its selective closure as a treatment for a spinal extradural arachnoid cyst. Spine (Phila Pa 1976) (2004) 1.14
Subaxial subluxation after atlantoaxial transarticular screw fixation in rheumatoid patients. Eur Spine J (2009) 1.13
Structure and operation of the DNA-translocating type I DNA restriction enzymes. Genes Dev (2012) 1.13
Non-muscle myosins 2A and 2B drive changes in cell morphology that occur as myoblasts align and fuse. J Cell Sci (2006) 1.11
Human myosin Vc is a low duty ratio, nonprocessive molecular motor. J Biol Chem (2008) 1.11
Myosin regulatory light chain (RLC) phosphorylation change as a modulator of cardiac muscle contraction in disease. J Biol Chem (2013) 1.10
Molecular rulers? Curr Biol (2012) 1.09
Myosin VI and its binding partner optineurin are involved in secretory vesicle fusion at the plasma membrane. Mol Biol Cell (2010) 1.09
In vitro reconstitution of a transport complex containing Rab27a, melanophilin and myosin Va. FEBS Lett (2006) 1.08
Kinetic mechanism of myosinV-S1 using a new fluorescent ATP analogue. Biochemistry (2006) 1.06
Mechanical properties of inner-arm dynein-f (dynein I1) studied with in vitro motility assays. Biophys J (2007) 1.06
Gamma-aminobutyric acid as a promoting factor of cancer metastasis; induction of matrix metalloproteinase production is potentially its underlying mechanism. Cancer Res (2003) 1.06
Folding and regulation in myosins II and V. J Muscle Res Cell Motil (2008) 1.06
Delayed postoperative spinal epidural hematoma causing tetraplegia. Case report. J Neurosurg Spine (2006) 1.04
Kinetic characterization of nonmuscle myosin IIb at the single molecule level. J Biol Chem (2012) 1.02
3D reconstruction of mammalian septin filaments. J Mol Biol (2007) 1.02
Switch 1 mutation S217A converts myosin V into a low duty ratio motor. J Biol Chem (2008) 1.01
Kinetics of muscle contraction and actomyosin NTP hydrolysis from rabbit using a series of metal-nucleotide substrates. J Physiol (2004) 1.01
Is the dynein motor a winch? Curr Opin Struct Biol (2004) 1.01
Roles of titin in the structure and elasticity of the sarcomere. J Biomed Biotechnol (2010) 1.00
Dimerized Drosophila myosin VIIa: a processive motor. Proc Natl Acad Sci U S A (2006) 0.99