Published in Nucleic Acids Res on April 25, 1984
Codon usage in yeast: cluster analysis clearly differentiates highly and lowly expressed genes. Nucleic Acids Res (1986) 7.89
GTP-binding domain: three consensus sequence elements with distinct spacing. Proc Natl Acad Sci U S A (1987) 5.16
A novel GTP-binding protein, Sar1p, is involved in transport from the endoplasmic reticulum to the Golgi apparatus. J Cell Biol (1989) 4.29
Harvey murine sarcoma virus p21 ras protein: biological and biochemical significance of the cysteine nearest the carboxy terminus. EMBO J (1984) 4.28
Cloning and characterization of the high-affinity cAMP phosphodiesterase of Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1986) 3.19
Expression of p21 proteins in Escherichia coli and stereochemistry of the nucleotide-binding site. EMBO J (1986) 2.85
RAS2 of Saccharomyces cerevisiae is required for gluconeogenic growth and proper response to nutrient limitation. Proc Natl Acad Sci U S A (1985) 2.67
Involvement of ras in sexual differentiation but not in growth control in fission yeast. EMBO J (1986) 2.31
Isolation and characterization of a mammalian gene encoding a high-affinity cAMP phosphodiesterase. Proc Natl Acad Sci U S A (1989) 2.31
A gene which encodes a predicted protein kinase can restore some functions of the ras gene in fission yeast. EMBO J (1988) 2.02
RAS genes and growth control in Saccharomyces cerevisiae. J Bacteriol (1986) 1.92
The ras oncogene--an important regulatory element in lower eucaryotic organisms. Microbiol Rev (1989) 1.79
Requirement of one functional RAS gene and inability of an oncogenic ras variant to mediate the glucose-induced cyclic AMP signal in the yeast Saccharomyces cerevisiae. Mol Cell Biol (1988) 1.45
Carbon source regulation of RAS1 expression in Saccharomyces cerevisiae and the phenotypes of ras2- cells. Proc Natl Acad Sci U S A (1986) 1.42
SRA5 encodes the low-Km cyclic AMP phosphodiesterase of Saccharomyces cerevisiae. Mol Cell Biol (1988) 1.35
Reconstitution of the GTP-dependent adenylate cyclase from products of the yeast CYR1 and RAS2 genes in Escherichia coli. Proc Natl Acad Sci U S A (1985) 1.32
Saccharomyces cerevisiae cdc15 mutants arrested at a late stage in anaphase are rescued by Xenopus cDNAs encoding N-ras or a protein with beta-transducin repeats. Mol Cell Biol (1993) 1.27
Expression and characterization of ras mRNAs from Saccharomyces cerevisiae. Mol Cell Biol (1984) 1.21
Histone H3 and H4 gene deletions in Saccharomyces cerevisiae. J Cell Biol (1988) 1.20
The activation of adenylate cyclase by guanyl nucleotides in Saccharomyces cerevisiae is controlled by the CDC25 start gene product. Mol Cell Biol (1987) 1.17
Regulated expression of ras gene constructs in Dictyostelium transformants. Proc Natl Acad Sci U S A (1985) 1.16
Transforming p21 ras protein: flexibility in the major variable region linking the catalytic and membrane-anchoring domains. EMBO J (1985) 1.16
Yeast omnipotent supressor SUP1 (SUP45): nucleotide sequence of the wildtype and a mutant gene. Nucleic Acids Res (1986) 1.15
Characterization of functional domains of p21 ras by use of chimeric genes. EMBO J (1985) 0.99
Multiple regulatory mechanisms control the expression of the RAS1 and RAS2 genes of Saccharomyces cerevisiae. EMBO J (1988) 0.99
Yeast mutants temperature-sensitive for growth after random mutagenesis of the chromosomal RAS2 gene and deletion of the RAS1 gene. EMBO J (1988) 0.97
A new RAS mutation that suppresses the CDC25 gene requirement for growth of Saccharomyces cerevisiae. Mol Cell Biol (1988) 0.95
Conserved cis-elements bind a protein complex that regulates Drosophila ras2/rop bidirectional expression. Br J Cancer (1994) 0.93
Expression of ras cellular oncogenes during development of Drosophila melanogaster. Mol Cell Biol (1985) 0.87
Regulation of respiratory growth by Ras: the glyoxylate cycle mutant, cit2Delta, is suppressed by RAS2. Curr Genet (2006) 0.84
Antibody of predetermined specificity to a carboxy-terminal region of H-ras gene products inhibits their guanine nucleotide-binding function. Mol Cell Biol (1985) 0.82
Transcriptional regulatory elements of the RAS2 gene of Saccharomyces cerevisiae. Nucleic Acids Res (1990) 0.78
The functional domain of adenylate cyclase associated with entry into meiosis in Saccharomyces cerevisiae. J Bacteriol (1990) 0.76
Complex regulation of Hsf1-Skn7 activities by the catalytic subunits of PKA in Saccharomyces cerevisiae: experimental and computational evidences. BMC Syst Biol (2015) 0.75
A new method for sequencing DNA. Proc Natl Acad Sci U S A (1977) 250.51
Mechanism of activation of a human oncogene. Nature (1982) 12.09
A point mutation is responsible for the acquisition of transforming properties by the T24 human bladder carcinoma oncogene. Nature (1982) 11.92
Evidence for an intron-contained sequence required for the splicing of yeast RNA polymerase II transcripts. Cell (1983) 6.48
Structure and organization of the human Ki-ras proto-oncogene and a related processed pseudogene. Nature (1983) 5.90
ras-Related gene sequences identified and isolated from Saccharomyces cerevisiae. Nature (1984) 5.32
A yeast gene encoding a protein homologous to the human c-has/bas proto-oncogene product. Nature (1984) 5.19
Structure of the Ki-ras gene of the human lung carcinoma cell line Calu-1. Nature (1983) 4.44
Induction of mammary carcinomas in rats by nitroso-methylurea involves malignant activation of H-ras-1 locus by single point mutations. Nature (1984) 4.38
Acquisition of transforming properties by alternative point mutations within c-bas/has human proto-oncogene. Nature (1983) 4.34
Guanine nucleotide-binding activity as an assay for src protein of rat-derived murine sarcoma viruses. Proc Natl Acad Sci U S A (1979) 4.34
Transcription terminates in yeast distal to a control sequence. Cell (1983) 3.40
Proposal for naming host cell-derived inserts in retrovirus genomes. J Virol (1981) 3.18
Identification of a precursor in the biosynthesis of the p21 transforming protein of harvey murine sarcoma virus. J Virol (1982) 2.89
Characterization of the phosphorylation sites and the surrounding amino acid sequences of the p21 transforming proteins coded for by the Harvey and Kirsten strains of murine sarcoma viruses. J Biol Chem (1982) 2.59
Saccharomyces cerevisiae synthesizes proteins related to the p21 gene product of ras genes found in mammals. Mol Cell Biol (1984) 1.53
The genome of simian virus 40. Science (1978) 24.46
Simian virus 40 tandem repeated sequences as an element of the early promoter. Proc Natl Acad Sci U S A (1981) 13.67
Mechanism of activation of a human oncogene. Nature (1982) 12.09
Active human immunodeficiency virus protease is required for viral infectivity. Proc Natl Acad Sci U S A (1988) 10.77
Monoclonal antibodies to the p21 products of the transforming gene of Harvey murine sarcoma virus and of the cellular ras gene family. J Virol (1982) 8.88
The p21 src genes of Harvey and Kirsten sarcoma viruses originate from divergent members of a family of normal vertebrate genes. Nature (1981) 8.44
Nucleotide sequences of integrated Moloney sarcoma provirus long terminal repeats and their host and viral junctions. Proc Natl Acad Sci U S A (1980) 7.77
Helper-independent transformation by unintegrated Harvey sarcoma virus DNA. J Virol (1978) 7.75
Whole-genome association study of bipolar disorder. Mol Psychiatry (2008) 6.80
Induction of murine C-type viruses from clonal lines of virus-free BALB-3T3 cells. Science (1971) 6.71
Intrinsic GTPase activity distinguishes normal and oncogenic ras p21 molecules. Proc Natl Acad Sci U S A (1984) 6.45
The genome of human papovavirus BKV. Cell (1979) 6.36
Cloning of bovine GAP and its interaction with oncogenic ras p21. Nature (1988) 5.56
Analysis of two divergent rat genomic clones homologous to the transforming gene of Harvey murine sarcoma virus. Proc Natl Acad Sci U S A (1981) 5.51
ras-Related gene sequences identified and isolated from Saccharomyces cerevisiae. Nature (1984) 5.32
Studies on the nucleic acid sequences of Kirsten sarcoma virus: a model for formation of a mammalian RNA-containing sarcoma virus. J Virol (1973) 5.28
Increasing mortality due to end-stage liver disease in patients with human immunodeficiency virus infection. Clin Infect Dis (2001) 5.27
Tumorigenic transformation of mammalian cells induced by a normal human gene homologous to the oncogene of Harvey murine sarcoma virus. Nature (1982) 5.08
RNA in mammalian sarcoma virus transformed nonproducer cells homologous to murine leukemia virus RNA. Virology (1973) 5.04
Transfection of molecularly cloned Friend murine leukemia virus DNA yields a highly leukemogenic helper-independent type C virus. J Virol (1980) 4.91
BKV splice sequences based on analysis of preferred donor and acceptor sites. Nucleic Acids Res (1979) 4.86
The transforming proteins of Rous sarcoma virus, Harvey sarcoma virus and Abelson virus contain tightly bound lipid. Cell (1982) 4.66
Novel mechanism for RNA maturation: the leader sequences of simian virus 40 mRNA are not transcribed adjacent to the coding sequences. Proc Natl Acad Sci U S A (1977) 4.64
Dual evolutionary origin for the rat genetic sequences of Harvey murine sarcoma virus. J Virol (1980) 4.63
Construction and isolation of a transmissible retrovirus containing the src gene of Harvey murine sarcoma virus and the thymidine kinase gene of herpes simplex virus type 1. J Virol (1981) 4.54
Guanine nucleotide-binding and autophosphorylating activities associated with the p21src protein of Harvey murine sarcoma virus. Nature (1980) 4.43
Localization of the src gene product of the Harvey strain of MSV to plasma membrane of transformed cells by electron microscopic immunocytochemistry. Cell (1980) 4.35
Guanine nucleotide-binding activity as an assay for src protein of rat-derived murine sarcoma viruses. Proc Natl Acad Sci U S A (1979) 4.34
Mapping the spliced and unspliced late lytic SV40 RNAs. Cell (1978) 4.25
Requirement of either of a pair of ras-related genes of Saccharomyces cerevisiae for spore viability. Nature (1984) 4.23
Harvey sarcoma virus: a second murine type C sarcoma virus with rat genetic information. J Virol (1974) 3.92
Molecular cloning of the Harvey sarcoma virus closed circular DNA intermediates: initial structural and biological characterization. J Virol (1979) 3.90
Splicing as a requirement for biogenesis of functional 16S mRNA of simian virus 40. Proc Natl Acad Sci U S A (1979) 3.89
Separation of murine cellular and murine leukaemia virus DNA polymerases. Nat New Biol (1971) 3.71
Friend strain of spleen focus-forming virus: a recombinant between mouse type C ecotropic viral sequences and sequences related to xenotropic virus. J Virol (1977) 3.70
Friend strain of spleen focus-forming virus is a recombinant between ecotropic murine type C virus and the env gene region of xenotropic type C virus. Proc Natl Acad Sci U S A (1977) 3.62
Mutant ras-encoded proteins with altered nucleotide binding exert dominant biological effects. Proc Natl Acad Sci U S A (1986) 3.59
Nucleotide sequence of the p21 transforming protein of Harvey murine sarcoma virus. Science (1982) 3.55
Human genome contains four genes homologous to transforming genes of Harvey and Kirsten murine sarcoma viruses. Proc Natl Acad Sci U S A (1982) 3.48
Mutational analysis in a cohort of 224 tuberous sclerosis patients indicates increased severity of TSC2, compared with TSC1, disease in multiple organs. Am J Hum Genet (2000) 3.44
Separation of sarcoma virus-specific and leukemia virus-specific genetic sequences of Moloney sarcoma virus. Proc Natl Acad Sci U S A (1975) 3.28
Radioimmunoassay of mammalian type C viral proteins. I. Species specific reactions of murine and feline viruses. J Immunol (1972) 3.23
Proposal for naming host cell-derived inserts in retrovirus genomes. J Virol (1981) 3.18
Identification of effector residues and a neutralizing epitope of Ha-ras-encoded p21. Proc Natl Acad Sci U S A (1986) 3.11
Mammalian and yeast ras gene products: biological function in their heterologous systems. Science (1985) 3.03
Comparison of the nucleotide sequence of the messenger RNA for the major structural protein of SV40 with the DNA sequence encoding the amino acids of the protein. Nucleic Acids Res (1977) 3.00
p21 of Kirsten murine sarcoma virus is thermolabile in a viral mutant temperature sensitive for the maintenance of transformation. J Virol (1979) 2.94
Comparative biochemical properties of p21 ras molecules coded for by viral and cellular ras genes. J Virol (1982) 2.91
Radioimmunoassay of mammalian type-C viral proteins: interspecies antigenic reactivities of the major internal polypeptide. Proc Natl Acad Sci U S A (1972) 2.90
Identification of a precursor in the biosynthesis of the p21 transforming protein of harvey murine sarcoma virus. J Virol (1982) 2.89
Yeast and mammalian ras proteins have conserved biochemical properties. Nature (1985) 2.85
Distinct mechanism for antidepressant activity by blockade of central substance P receptors. Science (1998) 2.83
Processing and expression of early SV40 mRNA: a role for RNA conformation in splicing. Cell (1979) 2.80
Heteroduplex analysis of the sequence relations between the RNAs of mink cell focus-inducing and murine leukemia viruses. J Virol (1978) 2.79
Immunological characterization of primate C-type virus reverse transcriptases. Nat New Biol (1972) 2.73
Type C particle-positive and type C particle-negative rat cell lines: characterization of the coding capacity of endogenous sarcoma virus-specific RNA. J Virol (1976) 2.67
Comparison of the genomic organization of Kirsten and Harvey sarcoma viruses. J Virol (1978) 2.66
Immunological relationships of reverse transcriptases from ribonucleic acid tumor viruses. J Virol (1972) 2.65
A rapid enzymatic DNA sequencing technique: determination of sequence alterations in early simian virus 40 temperature sensitive and deletion mutants. Nucleic Acids Res (1980) 2.65
Selective inhibition of ras-dependent transformation by a farnesyltransferase inhibitor. Science (1993) 2.60
Characterization of the phosphorylation sites and the surrounding amino acid sequences of the p21 transforming proteins coded for by the Harvey and Kirsten strains of murine sarcoma viruses. J Biol Chem (1982) 2.59
Rapid leukemia induced by cloned friend strain of replicating murine type-C virus. Association with induction of xenotropic-related RNA sequences contained in spleen focus-forming virus. Virology (1978) 2.56
Structure of a large segment of the genome of simian virus 40 that does not encode known proteins. Proc Natl Acad Sci U S A (1977) 2.50
Modulation of guanine nucleotides bound to Ras in NIH3T3 cells by oncogenes, growth factors, and the GTPase activating protein (GAP). J Biol Chem (1990) 2.49
Helper-independent mink cell focus-inducing strains of Friend murine type-C virus: potential relationship to the origin of replication-defective spleen focus-forming virus. J Exp Med (1978) 2.48
Eukaryotic translation initiation factor 4GI is a cellular target for NS1 protein, a translational activator of influenza virus. Mol Cell Biol (2000) 2.48
Isolation of a fibroblast nonproducer cell line containing the Friend strain of the spleen focus-forming virus. Virology (1977) 2.47
Nature and distribution of feline sarcoma virus nucleotide sequences. J Virol (1979) 2.47
Functional organization of the Harvey murine sarcoma virus genome. J Virol (1980) 2.46
Flat revertants isolated from Kirsten sarcoma virus-transformed cells are resistant to the action of specific oncogenes. Proc Natl Acad Sci U S A (1983) 2.44
Purification of ras GTPase activating protein from bovine brain. Proc Natl Acad Sci U S A (1988) 2.41
The nucleotide sequence preceding an RNA polymerase initiation site on SV40 DNA. Part 2. The sequence of the early strand transcript. Nucleic Acids Res (1974) 2.40
Deletion mapping of moloney type C virus: polypeptide and nucleic acid expression in different transforming virus isolates. J Virol (1976) 2.39
Envelope gene sequences which encode the gp52 protein of spleen focus-forming virus are required for the induction of erythroid cell proliferation. J Virol (1982) 2.39
RNA dependent DNA polymerase activity in mammalian cells. Nature (1971) 2.37
Dexamethasone stimulation of murine mammary tumor virus expression: a tissue culture source of virus. Science (1974) 2.34
Nucleotide sequences of RNA transcribed in infected cells and by Escherichia coli RNA polymerase from a segment of simian virus 40 DNA. Proc Natl Acad Sci U S A (1974) 2.34
Identification of a 30S RNA with properties of a defective type C virus in murine cells. J Virol (1978) 2.34
Defective retrovirus-like 30S RNA species of rat and mouse cells are infectious if packaged by type C helper virus. J Virol (1979) 2.34
Steroid induction of mouse mammary tumor virus: effect upon synthesis and degradation of viral RNA. J Virol (1977) 2.26
Ketamine-induced deficits in auditory and visual context-dependent processing in healthy volunteers: implications for models of cognitive deficits in schizophrenia. Arch Gen Psychiatry (2000) 2.26
Identification of a normal vertebrate cell protein related to the p21 src of Harvey murine sarcoma virus. Virology (1980) 2.15
A C-terminal domain of GAP is sufficient to stimulate ras p21 GTPase activity. EMBO J (1989) 2.14
Radioimmunoassay of mammalian type C viral proteins. 3. Detection of viral antigen in normal murine cells and tissues. J Exp Med (1973) 2.13
Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder. Mol Psychiatry (2012) 2.09
Characterizatiion of rat genetic sequences of Kirsten sarcoma virus: distinct class of endogenous rat type C viral sequences. J Virol (1976) 2.09
Factors related to the development of CMV-specific CD8+ T cell response in CMV-seropositive solid organ transplant candidates. Am J Transplant (2015) 2.08
A mutation in the Schizosaccharomyces pombe rae1 gene causes defects in poly(A)+ RNA export and in the cytoskeleton. J Biol Chem (1995) 2.05
Transformation by cloned Harvey murine sarcoma virus DNA: efficiency increased by long terminal repeat DNA. Science (1980) 2.05
Clinical presentation of adult coeliac disease. Ir Med J (2011) 2.04