Published in Nucleic Acids Res on July 19, 2006
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Unexpected A-form formation of 4'-thioDNA in solution, revealed by NMR, and the implications as to the mechanism of nuclease resistance. Nucleic Acids Res (2008) 0.86
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Investigation of some properties of oligodeoxynucleotides containing 4'-thio-2'-deoxynucleotides: duplex hybridization and nuclease sensitivity. Nucleic Acids Res (1996) 1.07
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Improving RNA interference in mammalian cells by 4'-thio-modified small interfering RNA (siRNA): effect on siRNA activity and nuclease stability when used in combination with 2'-O-alkyl modifications. J Med Chem (2006) 1.04
New NTP analogs: the synthesis of 4'-thioUTP and 4'-thioCTP and their utility for SELEX. Nucleic Acids Res (2005) 1.00
Synthesis and physical and physiological properties of 4'-thioRNA: application to post-modification of RNA aptamer toward NF-kappaB. Nucleic Acids Res (2004) 1.00
RNA interference induced by siRNAs modified with 4'-thioribonucleosides in cultured mammalian cells. FEBS Lett (2005) 0.99
Synthesis and properties of oligodeoxynucleotides containing the analogue 2'-deoxy-4'-thiothymidine. Nucleic Acids Res (1993) 0.96
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4'-Thio-RNA: synthesis of mixed base 4'-thio-oligoribonucleotides, nuclease resistance, and base pairing properties with complementary single and double strand. Antisense Res Dev (1995) 0.92
Effect of a single 3'-methylene phosphonate linkage on the conformation of an A-DNA octamer double helix. Nucleic Acids Res (1991) 0.91
The crystal structure analysis of d(CGCGAASSCGCG)2, a synthetic DNA dodecamer duplex containing four 4'-thio-2'-deoxythymidine nucleotides. Nucleic Acids Res (1996) 0.91
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Functional SNPs in the distal promoter of the ST2 gene are associated with atopic dermatitis. Hum Mol Genet (2005) 1.70
LOXL1 genetic polymorphisms are associated with exfoliation glaucoma in the Japanese population. Mol Vis (2008) 1.61
Three susceptible loci associated with primary open-angle glaucoma identified by genome-wide association study in a Japanese population. Proc Natl Acad Sci U S A (2009) 1.51
Silencing of int6 gene restores function of the ischaemic hindlimb in a rat model of peripheral arterial disease. Cardiovasc Res (2011) 1.46
Differences in blast immunophenotypes among disease types in myelodysplastic syndromes: a multicenter validation study. Leuk Res (2012) 1.42
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Is macrocytosis a favourable prognostic factor in myelodysplastic syndrome patients without increased blasts? Br J Haematol (2003) 1.39
Mammalian 5-formyluracil-DNA glycosylase. 2. Role of SMUG1 uracil-DNA glycosylase in repair of 5-formyluracil and other oxidized and deaminated base lesions. Biochemistry (2003) 1.27
IL-33-mediated innate response and adaptive immune cells contribute to maximum responses of protease allergen-induced allergic airway inflammation. J Immunol (2013) 1.19
Diagnostic utility of flow cytometry in low-grade myelodysplastic syndromes: a prospective validation study. Haematologica (2009) 1.16
Functional promoter polymorphism in the TBX21 gene associated with aspirin-induced asthma. Hum Genet (2005) 1.14
Tumor-associated calcium signal transducer 2 is required for the proper subcellular localization of claudin 1 and 7: implications in the pathogenesis of gelatinous drop-like corneal dystrophy. Am J Pathol (2010) 1.09
The immunosuppressive agent mizoribine monophosphate forms a transition state analogue complex with inosine monophosphate dehydrogenase. Biochemistry (2003) 1.09
New base pairing motifs. The synthesis and thermal stability of oligodeoxynucleotides containing imidazopyridopyrimidine nucleosides with the ability to form four hydrogen bonds. J Am Chem Soc (2003) 1.08
Role of the IL-6 classic- and trans-signaling pathways in corneal sterile inflammation and wound healing. Invest Ophthalmol Vis Sci (2011) 1.08
Mutagenicity of 5-formylcytosine, an oxidation product of 5-methylcytosine, in DNA in mammalian cells. J Biochem (2002) 1.07
Association between IFNA genotype and the risk of sarcoidosis. Hum Genet (2004) 1.03
No enhancement of nuclear entry by direct conjugation of a nuclear localization signal peptide to linearized DNA. Bioconjug Chem (2003) 1.01
New NTP analogs: the synthesis of 4'-thioUTP and 4'-thioCTP and their utility for SELEX. Nucleic Acids Res (2005) 1.00
Repair of 2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine-induced DNA single-strand breaks by transcription-coupled nucleotide excision repair. Cancer Res (2008) 1.00
Synthesis and physical and physiological properties of 4'-thioRNA: application to post-modification of RNA aptamer toward NF-kappaB. Nucleic Acids Res (2004) 1.00
Synthesis of 1,8-naphthyridine C-nucleosides and their base-pairing properties in oligodeoxynucleotides: thermally stable naphthyridine:imidazopyridopyrimidine base-pairing motifs. Angew Chem Int Ed Engl (2005) 0.99
Total synthesis of caprazol, a core structure of the caprazamycin antituberculosis antibiotics. Angew Chem Int Ed Engl (2005) 0.99
RNA interference induced by siRNAs modified with 4'-thioribonucleosides in cultured mammalian cells. FEBS Lett (2005) 0.99
Periostin promotes the generation of fibrous membranes in proliferative vitreoretinopathy. FASEB J (2013) 0.97
Structural basis for the specificity, catalysis, and regulation of human uridine-cytidine kinase. Structure (2004) 0.97
Sensitivity of human cancer cells to the new anticancer ribo-nucleoside TAS-106 is correlated with expression of uridine-cytidine kinase 2. Jpn J Cancer Res (2002) 0.97
Long-term responses and outcomes following immunosuppressive therapy in large granular lymphocyte leukemia-associated pure red cell aplasia: a Nationwide Cohort Study in Japan for the PRCA Collaborative Study Group. Haematologica (2008) 0.96
A crucial role of uridine/cytidine kinase 2 in antitumor activity of 3'-ethynyl nucleosides. Drug Metab Dispos (2004) 0.94
Mechanistic analysis of muraymycin analogues: a guide to the design of MraY inhibitors. J Med Chem (2011) 0.94
Total synthesis of (-)-muraymycin D2 and its epimer. J Org Chem (2010) 0.94
Association of the IL12RB1 promoter polymorphisms with increased risk of atopic dermatitis and other allergic phenotypes. Hum Mol Genet (2005) 0.94
Induction of T --> G and T --> A transversions by 5-formyluracil in mammalian cells. Mutat Res (2002) 0.93
Synthesis of stable and cell-type selective analogues of cyclic ADP-ribose, a Ca(2+)-mobilizing second messenger. Structure--activity relationship of the N1-ribose moiety. J Am Chem Soc (2005) 0.93
Lattice corneal dystrophy type IV (p.Leu527Arg) is caused by a founder mutation of the TGFBI gene in a single Japanese ancestor. Invest Ophthalmol Vis Sci (2010) 0.92
Synthesis of caprazamycin analogues and their structure--activity relationship for antibacterial activity. J Org Chem (2007) 0.92
Mutagenicity of secondary oxidation products of 8-oxo-7,8-dihydro-2'-deoxyguanosine 5'-triphosphate (8-hydroxy-2'- deoxyguanosine 5'-triphosphate). Mutat Res (2011) 0.92
Molecular basis for G2 arrest induced by 2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine and consequences of checkpoint abrogation. Cancer Res (2005) 0.92
Novel hydrolysis-resistant analogues of cyclic ADP-ribose: modification of the "northern" ribose and calcium release activity. Biochemistry (2002) 0.91
Involvement of p27(KIP1) degradation by Skp2 in the regulation of proliferation in response to wounding of corneal epithelium. Invest Ophthalmol Vis Sci (2002) 0.91
New neplanocin analogues. 12. Alternative synthesis and antimalarial effect of (6'R)-6'-C-methylneplanocin A, a potent AdoHcy hydrolase inhibitor. J Med Chem (2002) 0.90
Synthesis, thermal stability and resistance to enzymatic hydrolysis of the oligonucleotides containing 5-(N-aminohexyl)carbamoyl-2'-O-methyluridines. Nucleic Acids Res (2003) 0.89
Mast cells function as an alternative modulator of adipogenesis through 15-deoxy-delta-12, 14-prostaglandin J2. Am J Physiol Cell Physiol (2011) 0.89
Characterization of a novel metalloproteinase in Duvernoy's gland of Rhabdophis tigrinus tigrinus. J Toxicol Sci (2006) 0.89
Ataxia-telangiectasia and Rad3-related and DNA-dependent protein kinase cooperate in G2 checkpoint activation by the DNA strand-breaking nucleoside analogue 2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine. Mol Cancer Ther (2008) 0.88
Association of RNase L with a Ras GTPase-activating-like protein IQGAP1 in mediating the apoptosis of a human cancer cell-line. FEBS J (2010) 0.88
Homologous recombination as a resistance mechanism to replication-induced double-strand breaks caused by the antileukemia agent CNDAC. Blood (2010) 0.88
IL-33, but not IL-25, is crucial for the development of house dust mite antigen-induced allergic rhinitis. PLoS One (2013) 0.88
The systemic administration of an anti-miRNA oligonucleotide encapsulated pH-sensitive liposome results in reduced level of hepatic microRNA-122 in mice. J Control Release (2014) 0.88
Functional haplotypes of IL-12B are associated with childhood atopic asthma. J Allergy Clin Immunol (2005) 0.88
In vitro selection of hairpin ribozymes activated with short oligonucleotides. Biochemistry (2002) 0.87
Synthesis of L-epi-capreomycidine derivatives via C-H amination. Org Lett (2011) 0.87
Perlecan-deficient mutation impairs corneal epithelial structure. Invest Ophthalmol Vis Sci (2012) 0.87
Treatment combining X-irradiation and a ribonucleoside anticancer drug, TAS106, effectively suppresses the growth of tumor cells transplanted in mice. Int J Radiat Oncol Biol Phys (2007) 0.87
Differences in epidemiology of MDS between Western and Eastern countries: Ethnic differences or environmental influence? Leuk Res (2006) 0.86
Unexpected A-form formation of 4'-thioDNA in solution, revealed by NMR, and the implications as to the mechanism of nuclease resistance. Nucleic Acids Res (2008) 0.86
A new arylsulfate sulfotransferase involved in liponucleoside antibiotic biosynthesis in streptomycetes. J Biol Chem (2010) 0.86
Structure-activity relationship of truncated analogs of caprazamycins as potential anti-tuberculosis agents. Bioorg Med Chem (2008) 0.86
2'/3'-O-peptidyl adenosine as a general base catalyst of its own external peptidyl transfer: implications for the ribosome catalytic mechanism. Chembiochem (2005) 0.86
Rolling circle amplification in a prokaryotic translation system using small circular RNA. Angew Chem Int Ed Engl (2013) 0.85
Study of modification pattern-RNAi activity relationships by using siRNAs modified with 4'-thioribonucleosides. Chembiochem (2007) 0.85
In vitro optimization of 2'-OMe-4'-thioribonucleoside-modified anti-microRNA oligonucleotides and its targeting delivery to mouse liver using a liposomal nanoparticle. Nucleic Acids Res (2013) 0.85
Identification of A-minor tertiary interactions within a bacterial group I intron active site by 3-deazaadenosine interference mapping. Biochemistry (2002) 0.85
Tremorgenic indole alkaloids. The total synthesis of (-)-penitrem D. J Am Chem Soc (2003) 0.85
Function-oriented synthesis of simplified caprazamycins: discovery of oxazolidine-containing uridine derivatives as antibacterial agents against drug-resistant bacteria. J Med Chem (2010) 0.85
Amplification of 4'-thioDNA in the presence of 4'-thio-dTTP and 4'-thio-dCTP, and 4'-thioDNA-directed transcription in vitro and in mammalian cells. J Am Chem Soc (2007) 0.85
Chemistry of cyclic ADP-ribose and its analogs. Curr Med Chem (2004) 0.85
Investigations toward the selection of fully-modified 4'-thioRNA aptamers: optimization of in vitro transcription steps in the presence of 4'-thioNTPs. Bioorg Med Chem (2008) 0.85
Mechanism of action of a new antitumor ribonucleoside, 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)cytosine (ECyd, TAS-106), differs from that of 5-fluorouracil. Oncol Rep (2007) 0.85
Construction of a cis-cyclopropane via reductive radical decarboxylation. Enantioselective synthesis of cis- and trans-1-arylpiperazyl-2-phenylcyclopropanes designed as antidopaminergic agents. J Org Chem (2003) 0.84
Selective recognition of unnatural imidazopyridopyrimidine:naphthyridine base pairs consisting of four hydrogen bonds by the Klenow fragment. J Am Chem Soc (2009) 0.84
Involvement of plasminogen activator inhibitor-1 in the pathogenesis of atopic cataracts. Invest Ophthalmol Vis Sci (2012) 0.84
Atopic Glaucoma: Clinical and Pathophysiological Analysis. J Glaucoma (2015) 0.83
A novel anticancer ribonucleoside, 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)cytosine, enhances radiation-induced cell death in tumor cells. Radiat Res (2004) 0.83
Development of a highly beta-selective ribosylation reaction without using neighboring group participation: total synthesis of (+)-caprazol, a core structure of caprazamycins. J Org Chem (2007) 0.83
Lack of association between the IL13 variant Arg110Gln and susceptibility to cedar pollinosis in a Japanese population. Int Arch Allergy Immunol (2005) 0.83
Triazole-linked dumbbell oligodeoxynucleotides with NF-kappaB binding ability as potential decoy molecules. J Org Chem (2008) 0.83
Monocyte chemotactic protein-1 levels in the vitreous of patients with proliferative vitreoretinopathy. Jpn J Ophthalmol (2002) 0.83
A nucleoside anticancer drug, 1-(3-C-ethynyl-β-D-ribo-pentofuranosyl)cytosine (TAS106), sensitizes cells to radiation by suppressing BRCA2 expression. Mol Cancer (2011) 0.82
Anticancer mechanisms of 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl) cytosine (ECyd, TAS-106). Nucleic Acids Res Suppl (2002) 0.82
Investigation of the corneal filament in filamentary keratitis. Invest Ophthalmol Vis Sci (2009) 0.82
Synthesis and characterization of 2'-modified-4'-thioRNA: a comprehensive comparison of nuclease stability. Nucleic Acids Res (2009) 0.82
Practical synthesis of 2'-deoxy-4'-thioribonucleosides: substrates for the synthesis of 4'-thioDNA. J Org Chem (2005) 0.82