Published in N Engl J Med on August 14, 2006
Dynamics of a cytokine storm. PLoS One (2012) 0.85
Radiotracers used for the scintigraphic detection of infection and inflammation. ScientificWorldJournal (2015) 0.80
Cytokine storm in a phase 1 trial of the anti-CD28 monoclonal antibody TGN1412. N Engl J Med (2006) 15.04
T-cell costimulation--biology, therapeutic potential, and challenges. N Engl J Med (2006) 2.81
Clinical trial registration: a statement from the International Committee of Medical Journal Editors. N Engl J Med (2004) 14.78
Clinical trial registration: a statement from the International Committee of Medical Journal Editors. JAMA (2004) 14.17
Statistics in medicine--reporting of subgroup analyses in clinical trials. N Engl J Med (2007) 12.55
Letting the genome out of the bottle--will we get our wish? N Engl J Med (2008) 9.10
Clinical trial registration: a statement from the International Committee of Medical Journal Editors. CMAJ (2004) 8.52
Clinical trial registration: a statement from the International Committee of Medical Journal Editors. Lancet (2004) 7.18
Data Sharing. N Engl J Med (2016) 5.12
Clinical trial registration: a statement from the International Committee of Medical Journal Editors. Ann Intern Med (2004) 5.06
Use of regularly scheduled albuterol treatment in asthma: genotype-stratified, randomised, placebo-controlled cross-over trial. Lancet (2004) 5.01
Financial associations of authors. N Engl J Med (2002) 4.85
Expression of concern: Bombardier et al., "Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis," N Engl J Med 2000;343:1520-8. N Engl J Med (2005) 4.48
Clinical trial registration--looking back and moving ahead. N Engl J Med (2007) 4.07
Sharing Clinical Trial Data: A Proposal From the International Committee of Medical Journal Editors. Ann Intern Med (2016) 3.95
Development of spontaneous airway changes consistent with human asthma in mice lacking T-bet. Science (2002) 3.91
Significant variability in response to inhaled corticosteroids for persistent asthma. J Allergy Clin Immunol (2002) 3.66
Registry research and medical privacy. N Engl J Med (2004) 3.49
Is this clinical trial fully registered?--A statement from the International Committee of Medical Journal Editors. N Engl J Med (2005) 3.44
Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 33-2002. A 28-year-old woman with ocular inflammation, fever, and headache. N Engl J Med (2002) 3.31
Physicians and execution. N Engl J Med (2008) 3.30
SARS, the Internet, and the Journal. N Engl J Med (2003) 3.16
Uniform definition of asthma severity, control, and exacerbations: document presented for the World Health Organization Consultation on Severe Asthma. J Allergy Clin Immunol (2010) 3.12
Sharing Clinical Trial Data--A Proposal from the International Committee of Medical Journal Editors. N Engl J Med (2016) 3.06
Multi-pronged inhibition of airway hyper-responsiveness and inflammation by lipoxin A(4). Nat Med (2002) 2.94
The lipoxin receptor ALX: potent ligand-specific and stereoselective actions in vivo. Pharmacol Rev (2006) 2.80
A sad day for science at the FDA. N Engl J Med (2005) 2.77
Prescriptions, privacy, and the First Amendment. N Engl J Med (2011) 2.75
Data Sharing and the Journal. N Engl J Med (2016) 2.74
Inappropriate advertising of dietary supplements. N Engl J Med (2003) 2.73
A patient with asthma seeks medical advice in 1828, 1928, and 2012. N Engl J Med (2012) 2.72
Controlling research trials. N Engl J Med (2003) 2.70
A pivotal medical-device case. N Engl J Med (2008) 2.69
Pharmacogenetic differences in response to albuterol between Puerto Ricans and Mexicans with asthma. Am J Respir Crit Care Med (2004) 2.62
The FDA, politics, and plan B. N Engl J Med (2004) 2.53
Mechanotransduction through growth-factor shedding into the extracellular space. Nature (2004) 2.48
Uniform format for disclosure of competing interests in ICMJE journals. N Engl J Med (2009) 2.46
Lower bronchodilator responsiveness in Puerto Rican than in Mexican subjects with asthma. Am J Respir Crit Care Med (2003) 2.39
Sharing clinical trial data: a proposal from the International Committee of Medical Journal Editors. Lancet (2016) 2.25
Systemic effect comparisons of six inhaled corticosteroid preparations. Am J Respir Crit Care Med (2002) 2.24
Genomewide linkage analysis of quantitative spirometric phenotypes in severe early-onset chronic obstructive pulmonary disease. Am J Hum Genet (2002) 2.23
Believe the data. N Engl J Med (2012) 2.20
Awake and informed. N Engl J Med (2004) 2.16
Is this clinical trial fully registered? A statement from the International Committee of Medical Journal Editors. Lancet (2005) 2.15
Public access to biomedical research. N Engl J Med (2004) 2.12
Sharing individual patient data from clinical trials. N Engl J Med (2015) 2.09
Legislative myopia on stem cells. N Engl J Med (2003) 2.03
COX-2 inhibitors--a lesson in unexpected problems. N Engl J Med (2005) 2.01
Expression of concern reaffirmed. N Engl J Med (2006) 1.97
Clinical trial registration. BMJ (2007) 1.95
Trial registration report card. N Engl J Med (2005) 1.89
Risks of long-acting beta-agonists in achieving asthma control. N Engl J Med (2009) 1.89
Clinical trial registration: looking back and moving ahead. Croat Med J (2007) 1.89
Endothelial nitric oxide synthase variants in cystic fibrosis lung disease. Am J Respir Crit Care Med (2002) 1.87
The Medical Device Safety Act of 2009. N Engl J Med (2009) 1.81
Bronchial epithelial compression regulates epidermal growth factor receptor family ligand expression in an autocrine manner. Am J Respir Cell Mol Biol (2005) 1.79
Revisiting the commercial-academic interface. N Engl J Med (2015) 1.79
Is this clinical trial fully registered? A statement from the International Committee of Medical Journal Editors. CMAJ (2005) 1.78
Exhaled nitric oxide as a diagnostic test for asthma: online versus offline techniques and effect of flow rate. Am J Respir Crit Care Med (2002) 1.76
Clinical trial registration: looking back and moving ahead. Ann Intern Med (2007) 1.71
Is this clinical trial fully registered? A statement from the International Committee of Medical Journal Editors. JAMA (2005) 1.65
Salvation by registration. N Engl J Med (2007) 1.63
Don't mess with the DSMB. N Engl J Med (2010) 1.60
Informed consent and SUPPORT. N Engl J Med (2013) 1.59
Toward more uniform conflict disclosures--the updated ICMJE conflict of interest reporting form. N Engl J Med (2010) 1.52
Decisions at the end of life. N Engl J Med (2003) 1.51
Physicians and the First Amendment. N Engl J Med (2008) 1.43
Sharing clinical trial data. BMJ (2016) 1.43
Is this clinical trial fully registered? A statement from the International Committee of Medical Journal Editors. Ann Intern Med (2005) 1.42
The growth of hospitalists and the changing face of primary care. N Engl J Med (2009) 1.42
The FDA and tobacco regulation. N Engl J Med (2008) 1.42
Peer review in the balance. N Engl J Med (2008) 1.42
[Clinical trial registration: a statement from the International Committee of Medical Journal Editors]. Tidsskr Nor Laegeforen (2004) 1.41
Clinical trial registration: a statement from the International Committee of Medical Journal Editors. Arch Dermatol (2005) 1.41
Bronchial epithelial compression regulates MAP kinase signaling and HB-EGF-like growth factor expression. Am J Physiol Lung Cell Mol Physiol (2002) 1.40
Choosing asthma step-up care. N Engl J Med (2010) 1.40
Embryonic stem-cell research--the case for federal funding. N Engl J Med (2004) 1.40
Clinical trial registration: a statement from the International Committee of Medical Journal Editors. Croat Med J (2004) 1.39
Full disclosure and the funding of biomedical research. N Engl J Med (2008) 1.38
Mechanical stress triggers selective release of fibrotic mediators from bronchial epithelium. Am J Respir Cell Mol Biol (2003) 1.36
Genome-wide linkage analysis of severe, early-onset chronic obstructive pulmonary disease: airflow obstruction and chronic bronchitis phenotypes. Hum Mol Genet (2002) 1.36
Family-based association analysis of beta2-adrenergic receptor polymorphisms in the childhood asthma management program. J Allergy Clin Immunol (2003) 1.34
CD14 tobacco gene-environment interaction modifies asthma severity and immunoglobulin E levels in Latinos with asthma. Am J Respir Crit Care Med (2005) 1.34
Open clinical trials. N Engl J Med (2007) 1.33
Uniform format for disclosure of competing interests in ICMJE journals. N Z Med J (2009) 1.33
Ebola and quarantine. N Engl J Med (2014) 1.32
H1N1 influenza A disease--information for health professionals. N Engl J Med (2009) 1.31
A glimpse of the next 100 years in medicine. N Engl J Med (2012) 1.30
TBX21: a functional variant predicts improvement in asthma with the use of inhaled corticosteroids. Proc Natl Acad Sci U S A (2004) 1.30
Considering recertification. N Engl J Med (2010) 1.28
Human papillomavirus vaccine--opportunity and challenge. N Engl J Med (2007) 1.22
Beta-agonists and asthma: too much of a good thing? J Clin Invest (2003) 1.20
The consumer and the learned intermediary in health care. N Engl J Med (2002) 1.20
Rethinking medical training--the critical work ahead. N Engl J Med (2002) 1.20
Differentiation-dependent responsiveness of bronchial epithelial cells to IL-4/13 stimulation. Am J Physiol Lung Cell Mol Physiol (2004) 1.17
Constitutive and cytokine-induced expression of the ETS transcription factor ESE-3 in the lung. Am J Respir Cell Mol Biol (2002) 1.16
Clinical trial registration: looking back and moving ahead. CMAJ (2007) 1.16
Uniform format for disclosure of competing interests in ICMJE Journals. Croat Med J (2009) 1.16
Clinical trial registration: looking back and moving ahead. JAMA (2007) 1.16
Interacting genetic loci cause airway hyperresponsiveness. Physiol Genomics (2005) 1.15
Clinical trial registration: looking back and moving ahead. Lancet (2007) 1.14
Pharmacogenetics of asthma. Am J Respir Crit Care Med (2002) 1.11