Published in Am J Respir Crit Care Med on November 14, 2003
Population stratification confounds genetic association studies among Latinos. Hum Genet (2005) 3.19
Recent genetic selection in the ancestral admixture of Puerto Ricans. Am J Hum Genet (2007) 2.72
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Fast and accurate inference of local ancestry in Latino populations. Bioinformatics (2012) 2.30
Genome-wide association study implicates chromosome 9q21.31 as a susceptibility locus for asthma in mexican children. PLoS Genet (2009) 2.27
Comparison of three methods to estimate genetic ancestry and control for stratification in genetic association studies among admixed populations. Hum Genet (2005) 2.19
ORMDL3 gene is associated with asthma in three ethnically diverse populations. Am J Respir Crit Care Med (2008) 2.18
Asthma in Hispanics. Am J Respir Crit Care Med (2005) 1.84
Genome-wide screen for asthma in Puerto Ricans: evidence for association with 5q23 region. Hum Genet (2008) 1.81
Novel susceptibility variants at 10p12.31-12.2 for childhood acute lymphoblastic leukemia in ethnically diverse populations. J Natl Cancer Inst (2013) 1.81
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Human genetics. The genetics of Mexico recapitulates Native American substructure and affects biomedical traits. Science (2014) 1.42
Ancestry-environment interactions and asthma risk among Puerto Ricans. Am J Respir Crit Care Med (2006) 1.42
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Asthma prevalence among US adults, 1998-2000: role of Puerto Rican ethnicity and behavioral and geographic factors. Am J Public Health (2006) 1.26
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Case-control admixture mapping in Latino populations enriches for known asthma-associated genes. J Allergy Clin Immunol (2012) 1.17
Genome-wide association study of breast cancer in Latinas identifies novel protective variants on 6q25. Nat Commun (2014) 1.16
Genetic ancestry influences asthma susceptibility and lung function among Latinos. J Allergy Clin Immunol (2014) 1.14
Immigration and acculturation-related factors and asthma morbidity in Latino children. J Pediatr Psychol (2011) 1.12
Analysis of Latino populations from GALA and MEC studies reveals genomic loci with biased local ancestry estimation. Bioinformatics (2013) 1.11
Admixture mapping identifies a locus on 6q25 associated with breast cancer risk in US Latinas. Hum Mol Genet (2012) 1.11
Identification of KIF3A as a novel candidate gene for childhood asthma using RNA expression and population allelic frequencies differences. PLoS One (2011) 1.10
Race, ethnicity and social class and the complex etiologies of asthma. Pharmacogenomics (2008) 1.09
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Applying epidemiologic concepts of primary, secondary, and tertiary prevention to the elimination of racial disparities in asthma. J Allergy Clin Immunol (2006) 1.05
A genome-wide association study of susceptibility to acute lymphoblastic leukemia in adolescents and young adults. Blood (2014) 1.04
Cosmopolitan and ethnic-specific replication of genetic risk factors for asthma in 2 Latino populations. J Allergy Clin Immunol (2011) 1.03
Amerindian-specific regions under positive selection harbour new lipid variants in Latinos. Nat Commun (2014) 1.02
A meta-analysis of genome-wide association studies for serum total IgE in diverse study populations. J Allergy Clin Immunol (2012) 1.01
Novel relationship of serum cholesterol with asthma and wheeze in the United States. J Allergy Clin Immunol (2009) 1.00
GSNO reductase and beta2-adrenergic receptor gene-gene interaction: bronchodilator responsiveness to albuterol. Pharmacogenet Genomics (2010) 1.00
Moving toward true inclusion of racial/ethnic minorities in federally funded studies. A key step for achieving respiratory health equality in the United States. Am J Respir Crit Care Med (2015) 1.00
The role of LTA4H and ALOX5AP genes in the risk for asthma in Latinos. Clin Exp Allergy (2010) 0.96
A genome-wide association study of bronchodilator response in Latinos implicates rare variants. J Allergy Clin Immunol (2013) 0.93
The role of caregivers' depressive symptoms and asthma beliefs on asthma outcomes among low-income Puerto Rican children. J Asthma (2009) 0.89
Whole-genome sequencing of individuals from a founder population identifies candidate genes for asthma. PLoS One (2014) 0.88
A new system identification approach to identify genetic variants in sequencing studies for a binary phenotype. Hum Hered (2014) 0.87
Identification of ATPAF1 as a novel candidate gene for asthma in children. J Allergy Clin Immunol (2011) 0.86
Genomewide association studies in allergy and the influence of ethnicity. Curr Opin Allergy Clin Immunol (2010) 0.83
The effect of parental social support and acculturation on childhood asthma control. J Asthma (2015) 0.81
ALOX5AP and LTA4H polymorphisms modify augmentation of bronchodilator responsiveness by leukotriene modifiers in Latinos. J Allergy Clin Immunol (2010) 0.81
Ethnic variability in persistent asthma after in utero tobacco exposure. Pediatrics (2011) 0.80
Polymorphism in Osteopontin Gene (SPP1) Is Associated with Asthma and Related Phenotypes in a Puerto Rican Population. Pediatr Allergy Immunol Pulmonol (2011) 0.80
Apolipoprotein ε4 is associated with lower brain volume in cognitively normal Chinese but not white older adults. PLoS One (2015) 0.79
Genetic and socioeconomic study of mate choice in Latinos reveals novel assortment patterns. Proc Natl Acad Sci U S A (2015) 0.77
PIGS: improved estimates of identity-by-descent probabilities by probabilistic IBD graph sampling. BMC Bioinformatics (2015) 0.77
Use of inhaled corticosteroids among Hispanics in the United States. Ann Am Thorac Soc (2015) 0.75
Health Issues in Hispanic/Latino Youth. J Lat Psychol (2016) 0.75
Resolving the etiology of atopic disorders by using genetic analysis of racial ancestry. J Allergy Clin Immunol (2016) 0.75
Role of interactions in pharmacogenetic studies: leukotrienes in asthma. Pharmacogenomics (2013) 0.75
Implications of population structure and ancestry on asthma genetic studies. Curr Opin Allergy Clin Immunol (2014) 0.75
Clinical trial registration: a statement from the International Committee of Medical Journal Editors. N Engl J Med (2004) 14.78
Clinical trial registration: a statement from the International Committee of Medical Journal Editors. JAMA (2004) 14.17
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An official American Thoracic Society/European Respiratory Society statement: asthma control and exacerbations: standardizing endpoints for clinical asthma trials and clinical practice. Am J Respir Crit Care Med (2009) 9.38
Letting the genome out of the bottle--will we get our wish? N Engl J Med (2008) 9.10
Clinical trial registration: a statement from the International Committee of Medical Journal Editors. CMAJ (2004) 8.52
The Salmeterol Multicenter Asthma Research Trial: a comparison of usual pharmacotherapy for asthma or usual pharmacotherapy plus salmeterol. Chest (2006) 8.43
Can guideline-defined asthma control be achieved? The Gaining Optimal Asthma ControL study. Am J Respir Crit Care Med (2004) 8.39
The importance of race and ethnic background in biomedical research and clinical practice. N Engl J Med (2003) 7.94
Genetic epidemiology of COPD (COPDGene) study design. COPD (2010) 7.67
Daily versus as-needed corticosteroids for mild persistent asthma. N Engl J Med (2005) 7.61
Microarray-based detection and genotyping of viral pathogens. Proc Natl Acad Sci U S A (2002) 7.27
Clinical trial registration: a statement from the International Committee of Medical Journal Editors. Lancet (2004) 7.18
Alveolar epithelial cell mesenchymal transition develops in vivo during pulmonary fibrosis and is regulated by the extracellular matrix. Proc Natl Acad Sci U S A (2006) 7.08
A genome-wide association study in chronic obstructive pulmonary disease (COPD): identification of two major susceptibility loci. PLoS Genet (2009) 6.93
Tiotropium bromide step-up therapy for adults with uncontrolled asthma. N Engl J Med (2010) 6.19
Changes in forced expiratory volume in 1 second over time in COPD. N Engl J Med (2011) 5.69
Family-based tests for associating haplotypes with general phenotype data: application to asthma genetics. Genet Epidemiol (2004) 5.57
Pulmonary arterial enlargement and acute exacerbations of COPD. N Engl J Med (2012) 5.54
Genomic screening and replication using the same data set in family-based association testing. Nat Genet (2005) 5.44
Characterisation of COPD heterogeneity in the ECLIPSE cohort. Respir Res (2010) 5.17
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Use of regularly scheduled albuterol treatment in asthma: genotype-stratified, randomised, placebo-controlled cross-over trial. Lancet (2004) 5.01
Loss of integrin alpha(v)beta8 on dendritic cells causes autoimmunity and colitis in mice. Nature (2007) 4.94
Enhanced pathological angiogenesis in mice lacking beta3 integrin or beta3 and beta5 integrins. Nat Med (2002) 4.87
Financial associations of authors. N Engl J Med (2002) 4.85
Categorization of humans in biomedical research: genes, race and disease. Genome Biol (2002) 4.84
Lung volumes and emphysema in smokers with interstitial lung abnormalities. N Engl J Med (2011) 4.75
PBAT: tools for family-based association studies. Am J Hum Genet (2004) 4.68
Direct effects of interleukin-13 on epithelial cells cause airway hyperreactivity and mucus overproduction in asthma. Nat Med (2002) 4.65
Serum vitamin D levels and markers of severity of childhood asthma in Costa Rica. Am J Respir Crit Care Med (2009) 4.64
The integrin alpha(v)beta8 mediates epithelial homeostasis through MT1-MMP-dependent activation of TGF-beta1. J Cell Biol (2002) 4.60
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Airway microbiota and bronchial hyperresponsiveness in patients with suboptimally controlled asthma. J Allergy Clin Immunol (2010) 4.38
Epidemiology of lung cancer: ACCP evidence-based clinical practice guidelines (2nd edition). Chest (2007) 4.29
Genome-wide profiling identifies epithelial cell genes associated with asthma and with treatment response to corticosteroids. Proc Natl Acad Sci U S A (2007) 4.21
Chronic obstructive pulmonary disease phenotypes: the future of COPD. Am J Respir Crit Care Med (2010) 4.19
Worldwide severity and control of asthma in children and adults: the global asthma insights and reality surveys. J Allergy Clin Immunol (2004) 4.17
Pan-viral screening of respiratory tract infections in adults with and without asthma reveals unexpected human coronavirus and human rhinovirus diversity. J Infect Dis (2007) 4.16
Clinical trial registration--looking back and moving ahead. N Engl J Med (2007) 4.07
Loss of integrin alpha(v)beta6-mediated TGF-beta activation causes Mmp12-dependent emphysema. Nature (2003) 4.02
Gene expression analysis reveals matrilysin as a key regulator of pulmonary fibrosis in mice and humans. Proc Natl Acad Sci U S A (2002) 4.00
GOLD 2011 disease severity classification in COPDGene: a prospective cohort study. Lancet Respir Med (2012) 3.98
Is vitamin D deficiency to blame for the asthma epidemic? J Allergy Clin Immunol (2007) 3.97
MMP12, lung function, and COPD in high-risk populations. N Engl J Med (2009) 3.96
Sharing Clinical Trial Data: A Proposal From the International Committee of Medical Journal Editors. Ann Intern Med (2016) 3.95
An official American Thoracic Society public policy statement: Novel risk factors and the global burden of chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2010) 3.92
Development of spontaneous airway changes consistent with human asthma in mice lacking T-bet. Science (2002) 3.91
Maternal intake of vitamin D during pregnancy and risk of recurrent wheeze in children at 3 y of age. Am J Clin Nutr (2007) 3.89
Efficacy of a tyrosine kinase inhibitor in idiopathic pulmonary fibrosis. N Engl J Med (2011) 3.85
Clinical diagnosis of hypersensitivity pneumonitis. Am J Respir Crit Care Med (2003) 3.81
Genomewide association between GLCCI1 and response to glucocorticoid therapy in asthma. N Engl J Med (2011) 3.80
A genome-wide association study of pulmonary function measures in the Framingham Heart Study. PLoS Genet (2009) 3.78
Airway wall thickening and emphysema show independent familial aggregation in chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2008) 3.70
Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. Nat Genet (2011) 3.68
Significant variability in response to inhaled corticosteroids for persistent asthma. J Allergy Clin Immunol (2002) 3.66
Reduced neutrophil count in people of African descent is due to a regulatory variant in the Duffy antigen receptor for chemokines gene. PLoS Genet (2009) 3.60
Serum vitamin D levels and severe asthma exacerbations in the Childhood Asthma Management Program study. J Allergy Clin Immunol (2010) 3.54
A multivariate family-based association test using generalized estimating equations: FBAT-GEE. Biostatistics (2003) 3.52
Latino populations: a unique opportunity for the study of race, genetics, and social environment in epidemiological research. Am J Public Health (2005) 3.50
Registry research and medical privacy. N Engl J Med (2004) 3.49
Variants in FAM13A are associated with chronic obstructive pulmonary disease. Nat Genet (2010) 3.44
Six-minute-walk test in chronic obstructive pulmonary disease: minimal clinically important difference for death or hospitalization. Am J Respir Crit Care Med (2012) 3.44
Is this clinical trial fully registered?--A statement from the International Committee of Medical Journal Editors. N Engl J Med (2005) 3.44
Genome-wide association analysis identifies PDE4D as an asthma-susceptibility gene. Am J Hum Genet (2009) 3.41
Maternal vitamin D intake during pregnancy and early childhood wheezing. Am J Clin Nutr (2007) 3.40
Targeting of αv integrin identifies a core molecular pathway that regulates fibrosis in several organs. Nat Med (2013) 3.35
On the replication of genetic associations: timing can be everything! Am J Hum Genet (2008) 3.32
Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 33-2002. A 28-year-old woman with ocular inflammation, fever, and headache. N Engl J Med (2002) 3.31
Genetic ancestry in lung-function predictions. N Engl J Med (2010) 3.30