Bing Lim

Author PubWeight™ 190.59‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells. Nat Genet 2006 20.76
2 A global map of p53 transcription-factor binding sites in the human genome. Cell 2006 20.65
3 A pattern-based method for the identification of MicroRNA binding sites and their corresponding heteroduplexes. Cell 2006 14.70
4 MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation. Nature 2008 9.83
5 Comment on " 'Stemness': transcriptional profiling of embryonic and adult stem cells" and "a stem cell molecular signature". Science 2003 8.79
6 Sall4 modulates embryonic stem cell pluripotency and early embryonic development by the transcriptional regulation of Pou5f1. Nat Cell Biol 2006 4.81
7 Reciprocal transcriptional regulation of Pou5f1 and Sox2 via the Oct4/Sox2 complex in embryonic stem cells. Mol Cell Biol 2005 4.54
8 MicroRNA-125b is a novel negative regulator of p53. Genes Dev 2009 4.43
9 Reprogramming of fibroblasts into induced pluripotent stem cells with orphan nuclear receptor Esrrb. Nat Cell Biol 2009 4.32
10 Glycine decarboxylase activity drives non-small cell lung cancer tumor-initiating cells and tumorigenesis. Cell 2012 3.92
11 A genome-wide RNAi screen reveals determinants of human embryonic stem cell identity. Nature 2010 3.84
12 Retinoic acid increases Foxp3+ regulatory T cells and inhibits development of Th17 cells by enhancing TGF-beta-driven Smad3 signaling and inhibiting IL-6 and IL-23 receptor expression. J Immunol 2008 3.37
13 Sall4 interacts with Nanog and co-occupies Nanog genomic sites in embryonic stem cells. J Biol Chem 2006 3.24
14 Transcriptome profiling of human and murine ESCs identifies divergent paths required to maintain the stem cell state. Stem Cells 2005 3.16
15 MicroRNAs induced during adipogenesis that accelerate fat cell development are downregulated in obesity. Diabetes 2009 3.02
16 Distal airway stem cells yield alveoli in vitro and during lung regeneration following H1N1 influenza infection. Cell 2011 3.00
17 miR-200 enhances mouse breast cancer cell colonization to form distant metastases. PLoS One 2009 2.97
18 The nuclear receptor Nr5a2 can replace Oct4 in the reprogramming of murine somatic cells to pluripotent cells. Cell Stem Cell 2010 2.89
19 Tbx3 improves the germ-line competency of induced pluripotent stem cells. Nature 2010 2.46
20 T-cell factor 3 regulates embryonic stem cell pluripotency and self-renewal by the transcriptional control of multiple lineage pathways. Stem Cells 2008 2.43
21 MicroRNA-134 modulates the differentiation of mouse embryonic stem cells, where it causes post-transcriptional attenuation of Nanog and LRH1. Stem Cells 2007 2.40
22 Sall4 regulates distinct transcription circuitries in different blastocyst-derived stem cell lineages. Cell Stem Cell 2008 2.28
23 Linking beta-catenin to androgen-signaling pathway. J Biol Chem 2002 2.27
24 Eset partners with Oct4 to restrict extraembryonic trophoblast lineage potential in embryonic stem cells. Genes Dev 2009 2.18
25 Derivation of clinically compliant MSCs from CD105+, CD24- differentiated human ESCs. Stem Cells 2006 2.11
26 MicroRNA-125b promotes neuronal differentiation in human cells by repressing multiple targets. Mol Cell Biol 2009 2.08
27 A precarious balance: pluripotency factors as lineage specifiers. Cell Stem Cell 2011 2.07
28 Genome-wide mapping of RELA(p65) binding identifies E2F1 as a transcriptional activator recruited by NF-kappaB upon TLR4 activation. Mol Cell 2007 2.05
29 Identification of common pathways mediating differentiation of bone marrow- and adipose tissue-derived human mesenchymal stem cells into three mesenchymal lineages. Stem Cells 2006 1.93
30 Protein kinase C α is a central signaling node and therapeutic target for breast cancer stem cells. Cancer Cell 2013 1.86
31 Conserved long noncoding RNAs transcriptionally regulated by Oct4 and Nanog modulate pluripotency in mouse embryonic stem cells. RNA 2009 1.78
32 RCP is a human breast cancer-promoting gene with Ras-activating function. J Clin Invest 2009 1.71
33 The transcriptome of human oocytes. Proc Natl Acad Sci U S A 2006 1.70
34 Conserved regulation of p53 network dosage by microRNA-125b occurs through evolving miRNA-target gene pairs. PLoS Genet 2011 1.55
35 Activin/Nodal signaling controls divergent transcriptional networks in human embryonic stem cells and in endoderm progenitors. Stem Cells 2011 1.51
36 Effects of ectopic Nanog and Oct4 overexpression on mesenchymal stem cells. Stem Cells Dev 2009 1.32
37 B-MYB is essential for normal cell cycle progression and chromosomal stability of embryonic stem cells. PLoS One 2008 1.32
38 Down-regulation of Myc is essential for terminal erythroid maturation. J Biol Chem 2010 1.30
39 hZimp10 is an androgen receptor co-activator and forms a complex with SUMO-1 at replication foci. EMBO J 2003 1.28
40 miR-191 regulates mouse erythroblast enucleation by down-regulating Riok3 and Mxi1. Genes Dev 2010 1.23
41 The hematopoiesis-specific GTP-binding protein RhoH is GTPase deficient and modulates activities of other Rho GTPases by an inhibitory function. Mol Cell Biol 2002 1.20
42 Graded Nodal/Activin signaling titrates conversion of quantitative phospho-Smad2 levels into qualitative embryonic stem cell fate decisions. PLoS Genet 2011 1.20
43 Stage-specific modulation of cortical neuronal development by Mmu-miR-134. Cereb Cortex 2011 1.19
44 Retracted Autoimmunity as the consequence of a spontaneous mutation in Rasgrp1. Immunity 2003 1.15
45 Pleiotrophin enhances clonal growth and long-term expansion of human embryonic stem cells. Stem Cells 2007 1.12
46 hZimp7, a novel PIAS-like protein, enhances androgen receptor-mediated transcription and interacts with SWI/SNF-like BAF complexes. Mol Endocrinol 2005 1.11
47 ZFP36L2 is required for self-renewal of early burst-forming unit erythroid progenitors. Nature 2013 1.08
48 Specific gene-regulation networks during the pre-implantation development of the pig embryo as revealed by deep sequencing. BMC Genomics 2014 1.04
49 Recreating pluripotency? Cell Stem Cell 2010 1.02
50 Generation of induced pluripotent stem cells from bovine embryonic fibroblast cells. Cell Res 2011 1.02
51 Zinc-finger protein 145, acting as an upstream regulator of SOX9, improves the differentiation potential of human mesenchymal stem cells for cartilage regeneration and repair. Arthritis Rheum 2011 1.00
52 Inhibition of SARS coronavirus infection in vitro with clinically approved antiviral drugs. Emerg Infect Dis 2004 0.96
53 RhoH is required to maintain the integrin LFA-1 in a nonadhesive state on lymphocytes. Nat Immunol 2004 0.93
54 Enrichment, detection and clinical significance of circulating tumor cells. Lab Chip 2013 0.92
55 Long-term expansion of human functional epidermal precursor cells: promotion of extensive amplification by low TGF-beta1 concentrations. J Cell Sci 2003 0.91
56 RhoH modulates pre-TCR and TCR signalling by regulating LCK. Cell Signal 2010 0.90
57 Molecular basis of immortalization of human mesenchymal stem cells by combination of p53 knockdown and human telomerase reverse transcriptase overexpression. Stem Cells Dev 2012 0.90
58 Human finger-prick induced pluripotent stem cells facilitate the development of stem cell banking. Stem Cells Transl Med 2014 0.88
59 Multiple checkpoint breach of B cell tolerance in Rasgrp1-deficient mice. J Immunol 2013 0.88
60 Induction of functional human macrophages from bone marrow promonocytes by M-CSF in humanized mice. J Immunol 2013 0.87
61 A novel strategy to derive iPS cells from porcine fibroblasts. Sci China Life Sci 2011 0.86
62 RhoH plays distinct roles in T-cell migrations induced by different doses of SDF1 alpha. Cell Signal 2010 0.85
63 Interactions between Notch- and hypoxia-induced transcriptomes in embryonic stem cells. Exp Cell Res 2009 0.85
64 CD14 promoter polymorphisms have no functional significance and are not associated with atopic phenotypes. Pharmacogenet Genomics 2006 0.85
65 CD166(pos) subpopulation from differentiated human ES and iPS cells support repair of acute lung injury. Mol Ther 2012 0.84
66 RhoGTPases and their role in cancer. Oncol Res 2003 0.84
67 Epigenetics: Actors in the cell reprogramming drama. Nature 2012 0.83
68 Elucidating the molecular physiopathology of acute respiratory distress syndrome in severe acute respiratory syndrome patients. Virus Res 2009 0.82
69 ARDS in SARS: cytokine mediators and treatment implications. Cytokine 2005 0.82
70 Glycine decarboxylase is an unusual amino acid decarboxylase involved in tumorigenesis. Biochemistry 2014 0.80
71 Mayven induces c-Jun expression and cyclin D1 activation in breast cancer cells. Oncogene 2005 0.79
72 The molecular basis of ageing in stem cells. Mech Ageing Dev 2006 0.79
73 Reconstitution of mammary epithelial morphogenesis by murine embryonic stem cells undergoing hematopoietic stem cell differentiation. PLoS One 2010 0.77
74 PI3 K/Akt/mTOR-mediated translational control regulates proliferation and differentiation of lineage-restricted RoSH stem cell lines. J Mol Signal 2007 0.77
75 Rejuvenating tithonus. EMBO Rep 2013 0.75
76 Stem cells: Close encounters with full potential. Nature 2013 0.75
77 Characterization of Rho-GDIgamma and Rho-GDIalpha mRNA in the developing and mature brain with an analysis of mice with targeted deletions of Rho-GDIgamma. Brain Res 2005 0.75
78 Corrigendum: Endothelin-1 supports clonal derivation and expansion of cardiovascular progenitors derived from human embryonic stem cells. Nat Commun 2016 0.75
79 Computer and statistical analysis of transcription factor binding and chromatin modifications by ChIP-seq data in embryonic stem cell. J Integr Bioinform 2012 0.75
80 Insights into the role of DNA methylation in murine embryonic stem cells using a modified tetracycline-inducible gene expression system. Oncol Res 2003 0.75