Published in Biochemistry on October 10, 2006
Chemoenzymatic synthesis of homogeneous ultralow molecular weight heparins. Science (2011) 2.79
Chemoenzymatic design of heparan sulfate oligosaccharides. J Biol Chem (2010) 1.64
The dominating role of N-deacetylase/N-sulfotransferase 1 in forming domain structures in heparan sulfate. J Biol Chem (2011) 1.06
Chemoenzymatic synthesis of heparan sulfate and heparin. Nat Prod Rep (2014) 1.03
Chemoenzymatic synthesis of uridine diphosphate-GlcNAc and uridine diphosphate-GalNAc analogs for the preparation of unnatural glycosaminoglycans. J Org Chem (2012) 0.93
Glucuronyltransferase activity of KfiC from Escherichia coli strain K5 requires association of KfiA: KfiC and KfiA are essential enzymes for production of K5 polysaccharide, N-acetylheparosan. J Biol Chem (2009) 0.89
In vitro synthesis of heparosan using recombinant Pasteurella multocida heparosan synthase PmHS2. Appl Microbiol Biotechnol (2009) 0.87
Structure/function analysis of Pasteurella multocida heparosan synthases: toward defining enzyme specificity and engineering novel catalysts. J Biol Chem (2012) 0.87
Analysis of the polymerization initiation and activity of Pasteurella multocida heparosan synthase PmHS2, an enzyme with glycosyltransferase and UDP-sugar hydrolase activity. J Biol Chem (2010) 0.85
Synthesis of uridine 5'-diphosphoiduronic acid: a potential substrate for the chemoenzymatic synthesis of heparin. J Org Chem (2008) 0.81
Preparation and application of a 'clickable' acceptor for enzymatic synthesis of heparin oligosaccharides. Carbohydr Res (2013) 0.79
De novo synthesis of a narrow size distribution low-molecular-weight heparin. Glycobiology (2014) 0.78
Bioengineered heparins and heparan sulfates. Adv Drug Deliv Rev (2015) 0.78
Intramolecular N-glycan/polypeptide interactions observed at multiple N-glycan remodeling steps through [(13)C,(15)N]-N-acetylglucosamine labeling of immunoglobulin G1. Biochemistry (2014) 0.78
The design and synthesis of new synthetic low-molecular-weight heparins. J Thromb Haemost (2016) 0.75
Prevalence of chronic kidney disease in China: a cross-sectional survey. Lancet (2012) 10.53
Focal loss of the glutamate transporter EAAT2 in a transgenic rat model of SOD1 mutant-mediated amyotrophic lateral sclerosis (ALS). Proc Natl Acad Sci U S A (2002) 4.37
A test of climate, sun, and culture relationships from an 1810-year Chinese cave record. Science (2008) 3.94
Mutant SOD1 causes motor neuron disease independent of copper chaperone-mediated copper loading. Nat Neurosci (2002) 3.09
Highly efficient capture of circulating tumor cells by using nanostructured silicon substrates with integrated chaotic micromixers. Angew Chem Int Ed Engl (2011) 2.79
Chemoenzymatic synthesis of homogeneous ultralow molecular weight heparins. Science (2011) 2.79
The density of small tight junction pores varies among cell types and is increased by expression of claudin-2. J Cell Sci (2008) 2.36
Clonal vaccinia virus grown in cell culture as a new smallpox vaccine. Nat Med (2003) 2.27
Common molecular signature in SOD1 for both sporadic and familial amyotrophic lateral sclerosis. Proc Natl Acad Sci U S A (2007) 2.25
Using an enzymatic combinatorial approach to identify anticoagulant heparan sulfate structures. Chem Biol (2007) 2.20
ZO-1 stabilizes the tight junction solute barrier through coupling to the perijunctional cytoskeleton. Mol Biol Cell (2009) 2.10
Solution structures of chemoenzymatically synthesized heparin and its precursors. J Am Chem Soc (2008) 2.02
Mast cells modulate the pathogenesis of elastase-induced abdominal aortic aneurysms in mice. J Clin Invest (2007) 2.00
Identification of two new loci at IL23R and RAB32 that influence susceptibility to leprosy. Nat Genet (2011) 1.95
Enzymatic redesigning of biologically active heparan sulfate. J Biol Chem (2005) 1.89
NPM-ALK transgenic mice spontaneously develop T-cell lymphomas and plasma cell tumors. Blood (2002) 1.87
High-throughput microarray detection of olfactory receptor gene expression in the mouse. Proc Natl Acad Sci U S A (2004) 1.82
Limb ischemic preconditioning reduces heart and lung injury after an open heart operation in infants. Pediatr Cardiol (2009) 1.81
Striatal enriched phosphatase 61 dephosphorylates Fyn at phosphotyrosine 420. J Biol Chem (2002) 1.78
Northern Hemisphere summer monsoon intensified by mega-El Nino/southern oscillation and Atlantic multidecadal oscillation. Proc Natl Acad Sci U S A (2013) 1.75
Heparan sulfate 3-O-sulfotransferase isoform 5 generates both an antithrombin-binding site and an entry receptor for herpes simplex virus, type 1. J Biol Chem (2002) 1.74
Implementation of ion/ion reactions in a quadrupole/time-of-flight tandem mass spectrometer. Anal Chem (2006) 1.72
Morpho-regulation of ectodermal organs: integument pathology and phenotypic variations in K14-Noggin engineered mice through modulation of bone morphogenic protein pathway. Am J Pathol (2004) 1.72
A live, attenuated recombinant West Nile virus vaccine. Proc Natl Acad Sci U S A (2006) 1.72
ACAM2000 clonal Vero cell culture vaccinia virus (New York City Board of Health strain)--a second-generation smallpox vaccine for biological defense. Int J Infect Dis (2004) 1.70
'Cyclic alopecia' in Msx2 mutants: defects in hair cycling and hair shaft differentiation. Development (2003) 1.70
Stretch-sensitive KCNQ1 mutation A link between genetic and environmental factors in the pathogenesis of atrial fibrillation? J Am Coll Cardiol (2007) 1.67
Deficiency and inhibition of cathepsin K reduce body weight gain and increase glucose metabolism in mice. Arterioscler Thromb Vasc Biol (2008) 1.64
Chemoenzymatic design of heparan sulfate oligosaccharides. J Biol Chem (2010) 1.64
Structural basis of Rab5-Rabaptin5 interaction in endocytosis. Nat Struct Mol Biol (2004) 1.57
Interface engineered BaTiO₃/SrTiO₃ heterostructures with optimized high-frequency dielectric properties. ACS Appl Mater Interfaces (2012) 1.52
A role for 3-O-sulfated heparan sulfate in cell fusion induced by herpes simplex virus type 1. J Gen Virol (2004) 1.51
Calcitriol restores renovascular function in estrogen-deficient rats through downregulation of cyclooxygenase-2 and the thromboxane-prostanoid receptor. Kidney Int (2013) 1.49
Bone morphogenic protein-4 contributes to venous endothelial dysfunction in patients with diabetes undergoing coronary revascularization. Ann Thorac Surg (2013) 1.46
Cathepsin L activity controls adipogenesis and glucose tolerance. Nat Cell Biol (2007) 1.46
LMP2/LMP7 gene variant: a risk factor for intestinal Mycobacterium tuberculosis infection in the Chinese population. J Gastroenterol Hepatol (2011) 1.45
Quantification of heparan sulfate disaccharides using ion-pairing reversed-phase microflow high-performance liquid chromatography with electrospray ionization trap mass spectrometry. Anal Chem (2009) 1.45
Role for 3-O-sulfated heparan sulfate as the receptor for herpes simplex virus type 1 entry into primary human corneal fibroblasts. J Virol (2006) 1.44
Critical role of mast cell chymase in mouse abdominal aortic aneurysm formation. Circulation (2009) 1.43
Genomic gains and losses are similar in genetic and histologic subsets of rhabdomyosarcoma, whereas amplification predominates in embryonal with anaplasia and alveolar subtypes. Genes Chromosomes Cancer (2002) 1.42
Structural analysis of the sulfotransferase (3-o-sulfotransferase isoform 3) involved in the biosynthesis of an entry receptor for herpes simplex virus 1. J Biol Chem (2004) 1.41
Design of biologically active heparan sulfate and heparin using an enzyme-based approach. Nat Prod Rep (2009) 1.39
Differentiating fall-prone and healthy adults using local dynamic stability. Ergonomics (2008) 1.39
Crystal structure and mutational analysis of heparan sulfate 3-O-sulfotransferase isoform 1. J Biol Chem (2004) 1.38
Activation of androgen receptor, lipogenesis, and oxidative stress converged by SREBP-1 is responsible for regulating growth and progression of prostate cancer cells. Mol Cancer Res (2011) 1.37
Optimization of supercritical carbon dioxide extraction of silkworm pupal oil applying the response surface methodology. Bioresour Technol (2009) 1.33
Intercalation of few-layer graphite flakes with FeCl3: Raman determination of Fermi level, layer by layer decoupling, and stability. J Am Chem Soc (2011) 1.33
Control of the heparosan N-deacetylation leads to an improved bioengineered heparin. Appl Microbiol Biotechnol (2011) 1.33
Engineering sulfotransferases to modify heparan sulfate. Nat Chem Biol (2008) 1.32
Characterization of heparan sulphate 3-O-sulphotransferase isoform 6 and its role in assisting the entry of herpes simplex virus type 1. Biochem J (2005) 1.31
Mating behaviour, life history and adaptation to insecticides determine species exclusion between whiteflies. J Anim Ecol (2010) 1.29
Dwarf 88, a novel putative esterase gene affecting architecture of rice plant. Plant Mol Biol (2009) 1.29
Enzymatic synthesis of heparin related polysaccharides on sensor chips: rapid screening of heparin-protein interactions. Biochem Biophys Res Commun (2005) 1.29
Lola regulates Drosophila olfactory projection neuron identity and targeting specificity. Neural Dev (2007) 1.28
Redox-dependent conformational changes in cytochrome C oxidase suggest a gating mechanism for proton uptake. Biochemistry (2009) 1.26
Chromosome 6 abnormalities are recurrent in synovial chondromatosis. Cancer Genet Cytogenet (2003) 1.24
Chiral sum frequency generation spectroscopy for characterizing protein secondary structures at interfaces. J Am Chem Soc (2011) 1.24
Isocyanate vapor-induced antigenicity of human albumin. J Allergy Clin Immunol (2004) 1.24
Classification and potential mechanisms of intravascular ultrasound patterns of stent fracture. Am J Cardiol (2009) 1.23
Molecular cloning and function analysis of the stay green gene in rice. Plant J (2007) 1.22
Cardiac hypertrophy in mice with long-chain acyl-CoA dehydrogenase or very long-chain acyl-CoA dehydrogenase deficiency. Lab Invest (2009) 1.22
Preactivation-based, one-pot combinatorial synthesis of heparin-like hexasaccharides for the analysis of heparin-protein interactions. Chemistry (2010) 1.22
Synthetic heparin. Curr Opin Pharmacol (2012) 1.21
Using a 3-O-sulfated heparin octasaccharide to inhibit the entry of herpes simplex virus type 1. Biochemistry (2008) 1.21
Adiponectin and its receptors are expressed in adult ventricular cardiomyocytes and upregulated by activation of peroxisome proliferator-activated receptor gamma. J Mol Cell Cardiol (2007) 1.21
miR-206 inhibits gastric cancer proliferation in part by repressing cyclinD2. Cancer Lett (2013) 1.21
Steady-state and transient kinetic analyses of taurine/alpha-ketoglutarate dioxygenase: effects of oxygen concentration, alternative sulfonates, and active-site variants on the FeIV-oxo intermediate. Biochemistry (2005) 1.21
Fiber-laser-based photoacoustic microscopy and melanoma cell detection. J Biomed Opt (2011) 1.21
Overexpression of aspartyl-(asparaginyl)-beta-hydroxylase in hepatocellular carcinoma is associated with worse surgical outcome. Hepatology (2010) 1.21
The TNF-α/ROS/HIF-1-induced upregulation of FoxMI expression promotes HCC proliferation and resistance to apoptosis. Carcinogenesis (2012) 1.20
Identification and distribution of Mycobacterium leprae genotypes in a region of high leprosy prevalence in China: a 3-year molecular epidemiological study. J Clin Microbiol (2007) 1.20
Carnitine palmitoyltransferase-1b deficiency aggravates pressure overload-induced cardiac hypertrophy caused by lipotoxicity. Circulation (2012) 1.20
Expression of heparan sulfate sulfotransferases in Kluyveromyces lactis and preparation of 3'-phosphoadenosine-5'-phosphosulfate. Glycobiology (2011) 1.19
Macrophage adiponectin expression improves insulin sensitivity and protects against inflammation and atherosclerosis. Diabetes (2010) 1.19
Identification and characterization of NARROW AND ROLLED LEAF 1, a novel gene regulating leaf morphology and plant architecture in rice. Plant Mol Biol (2010) 1.19
Peroxisome proliferator-activated receptor {delta} is an essential transcriptional regulator for mitochondrial protection and biogenesis in adult heart. Circ Res (2010) 1.19
An epidemiologic study of posttraumatic stress disorder in flood victims in Hunan China. Can J Psychiatry (2006) 1.18
Dipeptidyl peptidase 4 inhibitor sitagliptin protects endothelial function in hypertension through a glucagon-like peptide 1-dependent mechanism. Hypertension (2012) 1.18
Synthesis, DNA affinity, and antiprotozoal activity of linear dications: Terphenyl diamidines and analogues. J Med Chem (2006) 1.17
Inhibitory effect on cerebral inflammatory agents that accompany traumatic brain injury in a rat model: a potential neuroprotective mechanism of recombinant human erythropoietin (rhEPO). Neurosci Lett (2007) 1.16
Anti-heparan sulfate peptides that block herpes simplex virus infection in vivo. J Biol Chem (2011) 1.16
Genetic evolution of H9 subtype influenza viruses from live poultry markets in Shanghai, China. J Clin Microbiol (2009) 1.16
Predicting drug responsiveness in human cancers using genetically engineered mice. Clin Cancer Res (2013) 1.16
Transcriptional activation of c-myc proto-oncogene by WT1 protein. Oncogene (2004) 1.15
The biosynthesis of anticoagulant heparan sulfate by the heparan sulfate 3-O-sulfotransferase isoform 5. Biochim Biophys Acta (2004) 1.14
Developing compact multiphoton systems using femtosecond fiber lasers. J Biomed Opt (2009) 1.14
In vivo interference with Skp1 function leads to genetic instability and neoplastic transformation. Mol Cell Biol (2002) 1.13
Regulation of energy homeostasis by bombesin receptor subtype-3: selective receptor agonists for the treatment of obesity. Cell Metab (2010) 1.13
Comparative SNP and haplotype analysis reveals a higher genetic diversity and rapider LD decay in tropical than temperate germplasm in maize. PLoS One (2011) 1.13
Discovery of frequent homozygous deletions in chromosome 3p21.3 LUCA and AP20 regions in renal, lung and breast carcinomas. Oncogene (2004) 1.12
Prevalence of non-diabetic renal disease in patients with type 2 diabetes. Diabetes Res Clin Pract (2009) 1.12
In vivo versus in vitro airway surface liquid nicotine levels following cigarette smoke exposure. J Anal Toxicol (2008) 1.11
Dissecting the substrate recognition of 3-O-sulfotransferase for the biosynthesis of anticoagulant heparin. Proc Natl Acad Sci U S A (2012) 1.11
Brain reward deficits accompany withdrawal (hangover) from acute ethanol in rats. Alcohol (2006) 1.11
Antigenic changes in human albumin caused by reactivity with the occupational allergen diphenylmethane diisocyanate. Anal Biochem (2010) 1.10
Recent progress and applications in glycosaminoglycan and heparin research. Curr Opin Chem Biol (2009) 1.10
Human pallidothalamic and cerebellothalamic tracts: anatomical basis for functional stereotactic neurosurgery. Brain Struct Funct (2008) 1.10
Screening of metal-organic frameworks for carbon dioxide capture from flue gas using a combined experimental and modeling approach. J Am Chem Soc (2009) 1.09
Giant magnetoresistance and anomalous magnetic properties of highly epitaxial ferromagnetic LaBaCo2O(5.5+δ) thin films on (001) MgO. ACS Appl Mater Interfaces (2012) 1.09