Published in Proc Natl Acad Sci U S A on December 01, 1990
Sequences within and adjacent to the transmembrane segment of alpha-2,6-sialyltransferase specify Golgi retention. EMBO J (1991) 2.91
An investigation of the role of transmembrane domains in Golgi protein retention. EMBO J (1995) 2.71
Isolation of a mutant Arabidopsis plant that lacks N-acetyl glucosaminyl transferase I and is unable to synthesize Golgi-modified complex N-linked glycans. Plant Physiol (1993) 2.68
Kin recognition between medial Golgi enzymes in HeLa cells. EMBO J (1994) 2.62
Retrieval of TGN proteins from the cell surface requires endosomal acidification. EMBO J (1994) 2.56
Overlapping distribution of two glycosyltransferases in the Golgi apparatus of HeLa cells. J Cell Biol (1993) 2.50
OCH1 encodes a novel membrane bound mannosyltransferase: outer chain elongation of asparagine-linked oligosaccharides. EMBO J (1992) 2.29
Complex asparagine-linked oligosaccharides are required for morphogenic events during post-implantation development. EMBO J (1994) 1.97
Isolation of a matrix that binds medial Golgi enzymes. J Cell Biol (1994) 1.87
Expression cloning of a cDNA encoding UDP-GlcNAc:Gal beta 1-3-GalNAc-R (GlcNAc to GalNAc) beta 1-6GlcNAc transferase by gene transfer into CHO cells expressing polyoma large tumor antigen. Proc Natl Acad Sci U S A (1992) 1.79
The 17-residue transmembrane domain of beta-galactoside alpha 2,6-sialyltransferase is sufficient for Golgi retention. J Cell Biol (1992) 1.65
Scattered Golgi elements during microtubule disruption are initially enriched in trans-Golgi proteins. Mol Biol Cell (1998) 1.50
Structure and function of the Salmonella Typhi chimaeric A(2)B(5) typhoid toxin. Nature (2013) 1.37
Engineering the protein N-glycosylation pathway in insect cells for production of biantennary, complex N-glycans. Biochemistry (2002) 1.34
Requirement of N-glycan on GPI-anchored proteins for efficient binding of aerolysin but not Clostridium septicum alpha-toxin. EMBO J (2002) 1.33
Comparing N-glycan processing in mammalian cell lines to native and engineered lepidopteran insect cell lines. Glycoconj J (2004) 1.27
The joys of HexNAc. The synthesis and function of N- and O-glycan branches. Glycoconj J (2001) 1.23
Expression cloning of a human alpha1, 4-N-acetylglucosaminyltransferase that forms GlcNAcalpha1-->4Galbeta-->R, a glycan specifically expressed in the gastric gland mucous cell-type mucin. Proc Natl Acad Sci U S A (1999) 1.19
Arginine/lysine residues in the cytoplasmic tail promote ER export of plant glycosylation enzymes. Traffic (2008) 1.17
Cloning and expression of a novel UDP-GlcNAc:alpha-D-mannoside beta1,2-N-acetylglucosaminyltransferase homologous to UDP-GlcNAc:alpha-3-D-mannoside beta1,2-N-acetylglucosaminyltransferase I. Biochem J (2002) 1.10
Isolation and characterization of plant N-acetyl glucosaminyltransferase I (GntI) cDNA sequences. Functional analyses in the Arabidopsis cgl mutant and in antisense plants. Plant Physiol (2000) 1.01
The HB-6, CDw75, and CD76 differentiation antigens are unique cell-surface carbohydrate determinants generated by the beta-galactoside alpha 2,6-sialyltransferase. J Cell Biol (1992) 0.98
Ubiquilin-1 regulates amyloid precursor protein maturation and degradation by stimulating K63-linked polyubiquitination of lysine 688. Proc Natl Acad Sci U S A (2012) 0.97
Mammalian glycosylation mutants as tools for the analysis and reconstitution of protein transport. Biochem J (1991) 0.88
Genetic defect in N-acetylglucosaminyltransferase I gene of a ricin-resistant baby hamster kidney mutant. Biochem J (1998) 0.88
The effects of the site-directed removal of N-glycosylation sites from beta-1,4-N-acetylgalactosaminyltransferase on its function. Biochem J (1995) 0.88
Substrate specificities and intracellular distributions of three N-glycan processing enzymes functioning at a key branch point in the insect N-glycosylation pathway. J Biol Chem (2012) 0.88
Steady-state localization of a medial-Golgi glycosyltransferase involves transit through the trans-Golgi network. Biochem J (2001) 0.87
New insights into cathepsin D in mammary tissue development and remodeling. Cancer Biol Ther (2010) 0.87
Identification, characterization, and biosynthesis of a novel N-glycan modification in the fruiting body of the basidiomycete Coprinopsis cinerea. J Biol Chem (2010) 0.86
Genetic variants near the MGAT1 gene are associated with body weight, BMI and fatty acid metabolism among adults and children. Int J Obes (Lond) (2011) 0.86
N-acetylglucosaminyltransferase IVa regulates metastatic potential of mouse hepatocarcinoma cells through glycosylation of CD147. Glycoconj J (2012) 0.86
Production of active human glucocerebrosidase in seeds of Arabidopsis thaliana complex-glycan-deficient (cgl) plants. Glycobiology (2011) 0.86
Organization of the human beta-1,2-N-acetylglucosaminyltransferase I gene (MGAT1), which controls complex and hybrid N-glycan synthesis. Biochem J (1997) 0.85
A novel second isoenzyme of the human UDP-N-acetylglucosamine:alpha1,3-D-mannoside beta1,4-N-acetylglucosaminyltransferase family: cDNA cloning, expression, and chromosomal assignment. Glycoconj J (1998) 0.84
Discovery of mammalian genes that participate in virus infection. BMC Cell Biol (2004) 0.84
Mouse models for congenital disorders of glycosylation. J Inherit Metab Dis (2011) 0.81
Reduction in Golgi apparatus dimension in the absence of a residential protein, N-acetylglucosaminyltransferase V. Histochem Cell Biol (2014) 0.76
Producing recombinant therapeutic glycoproteins with enhanced sialylation using CHO-gmt4 glycosylation mutant cells. Bioengineered (2014) 0.75
Differential effects of human and plant N-acetylglucosaminyltransferase I (GnTI) in plants. Transgenic Res (2009) 0.75
Evolution of protein N-glycosylation process in Golgi apparatus which shapes diversity of protein N-glycan structures in plants, animals and fungi. Sci Rep (2017) 0.75
Bisecting GlcNAc structure is implicated in suppression of stroma-dependent haemopoiesis in transgenic mice expressing N-acetylglucosaminyltransferase III. Biochem J (1998) 0.75
Studies on the conformational behaviour of GlcNAc-Man3-GlcNAc2 oligosaccharides using molecular dynamics simulations. Glycoconj J (1998) 0.75
Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem (1987) 281.19
A simple method for displaying the hydropathic character of a protein. J Mol Biol (1982) 150.65
Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter. J Mol Appl Genet (1982) 54.79
A new computer method for the storage and manipulation of DNA gel reading data. Nucleic Acids Res (1980) 36.42
The scanning model for translation: an update. J Cell Biol (1989) 31.23
Assembly of asparagine-linked oligosaccharides. Annu Rev Biochem (1985) 26.05
Molecular cloning of a CD28 cDNA by a high-efficiency COS cell expression system. Proc Natl Acad Sci U S A (1987) 10.38
Using mini-prep plasmid DNA for sequencing double stranded templates with Sequenase. Biotechniques (1988) 10.14
Ubiquitous, interspersed repeated sequences in mammalian genomes. Proc Natl Acad Sci U S A (1980) 9.48
Multiple mechanisms of protein insertion into and across membranes. Science (1985) 7.70
Attachment of terminal N-acetylglucosamine to asparagine-linked oligosaccharides occurs in central cisternae of the Golgi stack. Cell (1985) 2.97
Deficient uridine diphosphate-N-acetylglucosamine:glycoprotein N-acetylglucosaminyltransferase activity in a clone of Chinese hamster ovary cells with altered surface glycoproteins. J Biol Chem (1975) 2.80
Specific changes in the oligosaccharide moieties of VSV grown in different lectin-resistnat CHO cells. Cell (1978) 2.30
Glycosylation mutants of animal cells. Annu Rev Genet (1984) 2.12
Isolation of a cDNA encoding a murine UDPgalactose:beta-D-galactosyl- 1,4-N-acetyl-D-glucosaminide alpha-1,3-galactosyltransferase: expression cloning by gene transfer. Proc Natl Acad Sci U S A (1989) 2.04
Molecular cloning, sequence, and expression of a human GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase cDNA that can form the H blood group antigen. Proc Natl Acad Sci U S A (1990) 2.00
A cloned human cDNA determines expression of a mouse stage-specific embryonic antigen and the Lewis blood group alpha(1,3/1,4)fucosyltransferase. Genes Dev (1990) 1.84
Chinese hamster ovary cells selected for resistance to the cytotoxicity of phytohemagglutinin are deficient in a UDP-N-acetylglucosamine--glycoprotein N-acetylglucosaminyltransferase activity. Proc Natl Acad Sci U S A (1975) 1.79
Bovine alpha 1----3-galactosyltransferase: isolation and characterization of a cDNA clone. Identification of homologous sequences in human genomic DNA. J Biol Chem (1989) 1.60
Structure of the altered oligosaccharide present in glycoproteins from a clone of Chinese hamster ovary cells deficient in N-acetylglucosaminyltransferase activity. J Biol Chem (1978) 1.55
Control of glycoprotein synthesis. Purification and characterization of rabbit liver UDP-N-acetylglucosamine:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I. J Biol Chem (1988) 1.21
Cloning and characterization of DNA complementary to human UDP-GalNAc: Fuc alpha 1----2Gal alpha 1----3GalNAc transferase (histo-blood group A transferase) mRNA. J Biol Chem (1990) 1.15
Lec1A Chinese hamster ovary cell mutants appear to arise from a structural alteration in N-acetylglucosaminyltransferase I. J Biol Chem (1986) 1.08
Conversion of a Golgi apparatus sialyltransferase to a secretory protein by replacement of the NH2-terminal signal anchor with a signal peptide. J Biol Chem (1989) 1.06
Purification and characterization of a rabbit liver alpha 1 goes to 3 mannoside beta 1 goes to 2 N-acetylglucosaminyltransferase. J Biol Chem (1981) 1.06
Stable expression of blood group H determinants and GDP-L-fucose: beta-D-galactoside 2-alpha-L-fucosyltransferase in mouse cells after transfection with human DNA. J Biol Chem (1989) 1.04
Transfection of a human gene that corrects the Lec1 glycosylation defect: evidence for transfer of the structural gene for N-acetylglucosaminyltransferase I. Mol Cell Biol (1989) 1.01
Developmentally regulated expression of cell surface carbohydrates during mouse embryogenesis. J Cell Biochem (1988) 0.99
Transfection of a human alpha-(1,3)fucosyltransferase gene into Chinese hamster ovary cells. Complications arise from activation of endogenous alpha-(1,3)fucosyltransferases. J Biol Chem (1990) 0.87
DNA-mediated transformation of N-acetylglucosaminyltransferase I activity into an enzyme deficient cell line. Biochem Biophys Res Commun (1989) 0.84
Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c. Cell (1996) 16.73
Ecological degradation in protected areas: the case of Wolong Nature Reserve for giant pandas. Science (2001) 6.52
A genomic screen of autism: evidence for a multilocus etiology. Am J Hum Genet (1999) 4.96
A fixative for intestinal parasites permitting the use of concentration and permanent staining procedures. Am J Clin Pathol (1977) 4.58
Tomotherapy: a new concept for the delivery of dynamic conformal radiotherapy. Med Phys (1994) 4.50
Circular intermediates of recombinant adeno-associated virus have defined structural characteristics responsible for long-term episomal persistence in muscle tissue. J Virol (1998) 4.17
Genome-wide association studies establish that human intelligence is highly heritable and polygenic. Mol Psychiatry (2011) 4.16
Fringe is a glycosyltransferase that modifies Notch. Nature (2000) 4.09
Estimation of pleiotropy between complex diseases using single-nucleotide polymorphism-derived genomic relationships and restricted maximum likelihood. Bioinformatics (2012) 3.97
Glutamate release promotes growth of malignant gliomas. Nat Med (2001) 3.67
Endosomal processing limits gene transfer to polarized airway epithelia by adeno-associated virus. J Clin Invest (2000) 3.57
Signaling and transcription in T helper development. Annu Rev Immunol (2000) 3.44
Ca2+ channel selectivity at a single locus for high-affinity Ca2+ interactions. Neuron (1995) 3.39
A protein encoded within the Down syndrome critical region is enriched in striated muscles and inhibits calcineurin signaling. J Biol Chem (2000) 3.26
Assignment of the membrane attachment, DNA binding, and transcriptional activation domains of sterol regulatory element-binding protein-1 (SREBP-1). J Biol Chem (1994) 3.09
Metastasis stage, adjuvant treatment, and residual tumor are prognostic factors for medulloblastoma in children: conclusions from the Children's Cancer Group 921 randomized phase III study. J Clin Oncol (1999) 3.08
Induction of apoptosis by the low-affinity NGF receptor. Science (1993) 3.04
ELAM-1--dependent cell adhesion to vascular endothelium determined by a transfected human fucosyltransferase cDNA. Cell (1990) 2.97
Dentinogenesis imperfecta 1 with or without progressive hearing loss is associated with distinct mutations in DSPP. Nat Genet (2001) 2.75
Retrohoming of a bacterial group II intron: mobility via complete reverse splicing, independent of homologous DNA recombination. Cell (1998) 2.74
Selection and characterization of eight phenotypically distinct lines of lectin-resistant Chinese hamster ovary cell. Cell (1975) 2.72
Highly attenuated vaccine strains of simian immunodeficiency virus protect against vaginal challenge: inverse relationship of degree of protection with level of attenuation. J Virol (1999) 2.69
Myocyte-enriched calcineurin-interacting protein, MCIP1, inhibits cardiac hypertrophy in vivo. Proc Natl Acad Sci U S A (2001) 2.64
Autophagy and chemotherapy resistance: a promising therapeutic target for cancer treatment. Cell Death Dis (2013) 2.52
Cloning and characterization of alpha1H from human heart, a member of the T-type Ca2+ channel gene family. Circ Res (1998) 2.49
Observation of the spin-Seebeck effect in a ferromagnetic semiconductor. Nat Mater (2010) 2.44
PKA: a portrait of protein kinase dynamics. Biochim Biophys Acta (2004) 2.43
A group II intron RNA is a catalytic component of a DNA endonuclease involved in intron mobility. Cell (1995) 2.37
MicroRNA miR-93 promotes tumor growth and angiogenesis by targeting integrin-β8. Oncogene (2010) 2.37
Specific changes in the oligosaccharide moieties of VSV grown in different lectin-resistnat CHO cells. Cell (1978) 2.30
High-frequency transfection of CHO cells using polybrene. Somat Cell Mol Genet (1986) 2.29
Primary structure and expression of a sodium channel characteristic of denervated and immature rat skeletal muscle. Neuron (1990) 2.23
Evaluation of unpreserved and preserved stools for the detection and identification of intestinal parasites. Am J Clin Pathol (1974) 2.23
Cleavage of sterol regulatory element binding proteins (SREBPs) by CPP32 during apoptosis. EMBO J (1996) 2.22
Survival and prognostic factors following radiation therapy and chemotherapy for ependymomas in children: a report of the Children's Cancer Group. J Neurosurg (1998) 2.22
Mice lacking N-acetylglucosaminyltransferase I activity die at mid-gestation, revealing an essential role for complex or hybrid N-linked carbohydrates. Proc Natl Acad Sci U S A (1994) 2.21
Identification of a titratable lysine residue that determines sensitivity of kidney potassium channels (ROMK) to intracellular pH. EMBO J (1996) 2.21
Impaired wound healing in mouse models of diabetes is mediated by TNF-alpha dysregulation and associated with enhanced activation of forkhead box O1 (FOXO1). Diabetologia (2009) 2.18
Ginsenoside-Rd improves outcome of acute ischaemic stroke - a randomized, double-blind, placebo-controlled, multicenter trial. Eur J Neurol (2012) 2.18
Sustained growth and three-dimensional organization of primary mammary tumor epithelial cells embedded in collagen gels. Proc Natl Acad Sci U S A (1979) 2.15
Functional domains of the Rsp5 ubiquitin-protein ligase. Mol Cell Biol (1999) 2.15
Translocation across Golgi vesicle membranes: a CHO glycosylation mutant deficient in CMP-sialic acid transport. Cell (1984) 2.15
Demonstration that mutation of the type II transforming growth factor beta receptor inactivates its tumor suppressor activity in replication error-positive colon carcinoma cells. J Biol Chem (1995) 2.15
Cell separation by dielectrophoretic field-flow-fractionation. Anal Chem (2000) 2.13
MEK kinase 1 is critically required for c-Jun N-terminal kinase activation by proinflammatory stimuli and growth factor-induced cell migration. Proc Natl Acad Sci U S A (2000) 2.12
Glycosylation mutants of animal cells. Annu Rev Genet (1984) 2.12
Hormones and mammary carcinogenesis in mice, rats, and humans: a unifying hypothesis. Proc Natl Acad Sci U S A (1995) 2.09
Regulation of proprioceptive memory by subarachnoid regional anesthesia. Anesthesiology (2000) 2.08
Endocytosis and nuclear trafficking of adeno-associated virus type 2 are controlled by rac1 and phosphatidylinositol-3 kinase activation. J Virol (2000) 2.08
Prediction of linear B-cell epitopes using amino acid pair antigenicity scale. Amino Acids (2007) 2.06
Mesenchymal to epithelial conversion in rat metanephros is induced by LIF. Cell (1999) 2.04
The removal of human breast cancer cells from hematopoietic CD34+ stem cells by dielectrophoretic field-flow-fractionation. J Hematother Stem Cell Res (1999) 2.03
Expression of human tissue factor under the control of the mouse tissue factor promoter mediates normal hemostasis in knock-in mice. J Thromb Haemost (2007) 2.00
The polypeptides of influenza virus. V. Localization of polypeptides in the virion by iodination techniques. Virology (1971) 2.00
Progress in high resolution atomic force microscopy in biology. Q Rev Biophys (1995) 1.99
Complementation between mutants of CHO cells resistant to a variety of plant lectins. Somatic Cell Genet (1977) 1.98
Regulation of Akt/PKB activation by tyrosine phosphorylation. J Biol Chem (2001) 1.98
Human insulin receptor monoclonal antibody undergoes high affinity binding to human brain capillaries in vitro and rapid transcytosis through the blood-brain barrier in vivo in the primate. Pharm Res (1995) 1.97
Characteristics of the in vitro assay of murine sarcoma virus (Moloney) and virus-infected cells. J Natl Cancer Inst (1968) 1.95
CD8+ T cell-dependent elimination of dendritic cells in vivo limits the induction of antitumor immunity. J Immunol (2000) 1.94
Mobility of yeast mitochondrial group II introns: engineering a new site specificity and retrohoming via full reverse splicing. Cell (1997) 1.91
Architecture of a K+ channel inner pore revealed by stoichiometric covalent modification. Neuron (1999) 1.90
Estrogen metabolism and risk of breast cancer: a prospective study of the 2:16alpha-hydroxyestrone ratio in premenopausal and postmenopausal women. Epidemiology (2000) 1.86
Decreased Ras-mitogen-activated protein kinase signaling may cause DNA hypomethylation in T lymphocytes from lupus patients. Arthritis Rheum (2001) 1.84
A cloned human cDNA determines expression of a mouse stage-specific embryonic antigen and the Lewis blood group alpha(1,3/1,4)fucosyltransferase. Genes Dev (1990) 1.84
Nanometer size diesel exhaust particles are selectively toxic to dopaminergic neurons: the role of microglia, phagocytosis, and NADPH oxidase. FASEB J (2004) 1.79
Chinese hamster ovary cells selected for resistance to the cytotoxicity of phytohemagglutinin are deficient in a UDP-N-acetylglucosamine--glycoprotein N-acetylglucosaminyltransferase activity. Proc Natl Acad Sci U S A (1975) 1.79
Expression of transforming growth factor beta type II receptor leads to reduced malignancy in human breast cancer MCF-7 cells. J Biol Chem (1994) 1.76
Probing ion permeation and gating in a K+ channel with backbone mutations in the selectivity filter. Nat Neurosci (2001) 1.76
A survey of the prevalence of Giardia in dogs presented to Canadian veterinary practices. Can Vet J (2001) 1.75
The Friedreich's ataxia mutation confers cellular sensitivity to oxidant stress which is rescued by chelators of iron and calcium and inhibitors of apoptosis. Hum Mol Genet (1999) 1.75
Insulin control of glycogen metabolism in knockout mice lacking the muscle-specific protein phosphatase PP1G/RGL. Mol Cell Biol (2001) 1.73
Cardiomyopathy in transgenic mice with cardiac-specific overexpression of serum response factor. Am J Physiol Heart Circ Physiol (2001) 1.72
Antibody blockade of thrombospondin accelerates reendothelialization and reduces neointima formation in balloon-injured rat carotid artery. Circulation (1999) 1.69
Communicating bronchopulmonary foregut malformations: classification and embryogenesis. J Pediatr Surg (1992) 1.68
A mouse model for mucopolysaccharidosis type III A (Sanfilippo syndrome). Glycobiology (1999) 1.67
Dendritic cells genetically engineered to express IL-4 inhibit murine collagen-induced arthritis. J Clin Invest (2001) 1.66
The origin of intermediary metabolism. Proc Natl Acad Sci U S A (2000) 1.66
Mitochondrial control of apoptosis: the role of cytochrome c. Biochim Biophys Acta (1998) 1.65
Sustained growth in primary culture of normal mammary epithelial cells embedded in collagen gels. Proc Natl Acad Sci U S A (1980) 1.65
Efficacy of a saccharin test for screening to detect abnormal mucociliary clearance. Br J Dis Chest (1984) 1.63
Deleterious effect of CTLA4-Ig on a Treg-dependent transplant model. Am J Transplant (2012) 1.61
Gene expression profiles in hepatitis C virus (HCV) and HIV coinfection: class prediction analyses before treatment predict the outcome of anti-HCV therapy among HIV-coinfected persons. J Infect Dis (2006) 1.60
Nuclear import of Cdk/cyclin complexes: identification of distinct mechanisms for import of Cdk2/cyclin E and Cdc2/cyclin B1. J Cell Biol (1999) 1.60
Modification of epidermal growth factor-like repeats with O-fucose. Molecular cloning and expression of a novel GDP-fucose protein O-fucosyltransferase. J Biol Chem (2001) 1.58
N-acetylcysteine in combination with nitroglycerin and streptokinase for the treatment of evolving acute myocardial infarction. Safety and biochemical effects. Circulation (1995) 1.58
Intestinal parasites in metropolitan Toronto day-care centres. Can Med Assoc J (1984) 1.58
Tissue-specific cytokine production during experimental acute pancreatitis. A probable mechanism for distant organ dysfunction. Dig Dis Sci (1997) 1.57
WW6: an embryonic stem cell line with an inert genetic marker that can be traced in chimeras. Proc Natl Acad Sci U S A (1995) 1.56
An extreme-sib-pair genome scan for genes regulating blood pressure. Am J Hum Genet (1999) 1.56
Regular articles: conditional disruption of hedgehog signaling pathway defines its critical role in hair development and regeneration. J Invest Dermatol (2000) 1.56
Hormonal prevention of breast cancer: mimicking the protective effect of pregnancy. Proc Natl Acad Sci U S A (1999) 1.56
Functionalization of carbon nanotubes by electrochemical reduction of aryl diazonium salts: a bucky paper electrode. J Am Chem Soc (2001) 1.56
Telomerase reverse transcriptase promotes epithelial-mesenchymal transition and stem cell-like traits in cancer cells. Oncogene (2012) 1.55
The evolving portrait of cancer metastasis. Cold Spring Harb Symp Quant Biol (2005) 1.55
Altered vitamin-D metabolism in pregnancy. Lancet (1977) 1.55
Tissue-specific and developmental stage-specific DNA binding by a mammalian SWI/SNF complex associated with human fetal-to-adult globin gene switching. Proc Natl Acad Sci U S A (1999) 1.53
Common SNPs explain some of the variation in the personality dimensions of neuroticism and extraversion. Transl Psychiatry (2012) 1.52