Published in Biochemistry on November 07, 2006
The subcellular distribution of calnexin is mediated by PACS-2. Mol Biol Cell (2008) 1.51
Peptide-based interactions with calnexin target misassembled membrane proteins into endoplasmic reticulum-derived multilamellar bodies. J Mol Biol (2008) 0.95
Calnexin is involved in apoptosis induced by endoplasmic reticulum stress in the fission yeast. Mol Biol Cell (2008) 0.91
Calnexin regulates apoptosis induced by inositol starvation in fission yeast. PLoS One (2009) 0.86
Of yeast, mice and men: MAMs come in two flavors. Biol Direct (2017) 0.75
IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response. Genes Dev (2002) 6.37
Cell-surface calreticulin initiates clearance of viable or apoptotic cells through trans-activation of LRP on the phagocyte. Cell (2005) 5.90
T cell responses are better correlates of vaccine protection in the elderly. J Immunol (2006) 4.38
Calreticulin, a multi-process calcium-buffering chaperone of the endoplasmic reticulum. Biochem J (2009) 3.34
Cytotoxic T lymphocytes: all roads lead to death. Nat Rev Immunol (2002) 3.01
Calreticulin: non-endoplasmic reticulum functions in physiology and disease. FASEB J (2009) 2.48
The X-ray structure of a BAK homodimer reveals an inhibitory zinc binding site. Mol Cell (2006) 2.24
The role of Nogo and the mitochondria-endoplasmic reticulum unit in pulmonary hypertension. Sci Transl Med (2011) 1.95
Calreticulin signaling in health and disease. Int J Biochem Cell Biol (2012) 1.81
Biology of endoplasmic reticulum stress in the heart. Circ Res (2010) 1.78
Calreticulin, a Ca2+-binding chaperone of the endoplasmic reticulum. Int J Biochem Cell Biol (2005) 1.77
Granzyme B induces smooth muscle cell apoptosis in the absence of perforin: involvement of extracellular matrix degradation. Arterioscler Thromb Vasc Biol (2004) 1.75
Granzyme B: Correlates with protection and enhanced CTL response to influenza vaccination in older adults. Vaccine (2009) 1.69
Contrasting functions of calreticulin and calnexin in glycoprotein folding and ER quality control. Mol Cell (2004) 1.62
Granzyme B: a natural born killer. Immunol Rev (2003) 1.61
Perforin pores in the endosomal membrane trigger the release of endocytosed granzyme B into the cytosol of target cells. Nat Immunol (2011) 1.57
Pyruvate dehydrogenase inhibition by the inflammatory cytokine TNFα contributes to the pathogenesis of pulmonary arterial hypertension. J Mol Med (Berl) (2011) 1.56
Competition of CUGBP1 and calreticulin for the regulation of p21 translation determines cell fate. EMBO J (2004) 1.54
Assembly and antigen-presenting function of MHC class I molecules in cells lacking the ER chaperone calreticulin. Immunity (2002) 1.54
The unmet need in the elderly: how immunosenescence, CMV infection, co-morbidities and frailty are a challenge for the development of more effective influenza vaccines. Vaccine (2012) 1.54
Cytotoxic T lymphocytes overcome Bcl-2 inhibition: target cells contribute to their own demise. Blood (2007) 1.52
Calcium-binding proteins and calcium-release channels in human maturing oocytes, pronuclear zygotes and early preimplantation embryos. Hum Reprod (2002) 1.52
Endoplasmic reticulum quality control and apoptosis. Acta Biochim Pol (2005) 1.45
Diversity of the protein disulfide isomerase family: identification of breast tumor induced Hag2 and Hag3 as novel members of the protein family. Mol Phylogenet Evol (2005) 1.44
The myxoma poxvirus protein, M11L, prevents apoptosis by direct interaction with the mitochondrial permeability transition pore. J Exp Med (2002) 1.39
Cellular functions of endoplasmic reticulum chaperones calreticulin, calnexin, and ERp57. Int Rev Cytol (2005) 1.32
Calcium signalling: past, present and future. Cell Calcium (2005) 1.31
The anti-adhesive activity of thrombospondin is mediated by the N-terminal domain of cell surface calreticulin. J Biol Chem (2002) 1.23
Initiation of embryonic cardiac pacemaker activity by inositol 1,4,5-trisphosphate-dependent calcium signaling. Mol Biol Cell (2005) 1.23
ERp19 and ERp46, new members of the thioredoxin family of endoplasmic reticulum proteins. Mol Cell Proteomics (2003) 1.22
ERp57, a multifunctional endoplasmic reticulum resident oxidoreductase. Int J Biochem Cell Biol (2010) 1.20
Granzyme B-induced apoptosis requires both direct caspase activation and relief of caspase inhibition. Immunity (2003) 1.20
Calcium binding chaperones of the endoplasmic reticulum. Gen Physiol Biophys (2009) 1.19
Calreticulin differentially modulates calcium uptake and release in the endoplasmic reticulum and mitochondria. J Biol Chem (2002) 1.18
ERp57 modulates STAT3 signaling from the lumen of the endoplasmic reticulum. J Biol Chem (2009) 1.16
Expression of CTL associated transcripts precedes the development of tubulitis in T-cell mediated kidney graft rejection. Am J Transplant (2005) 1.16
Granule-mediated killing by granzyme B and perforin requires a mannose 6-phosphate receptor and is augmented by cell surface heparan sulfate. Mol Biol Cell (2005) 1.15
Cardiac-specific expression of calcineurin reverses embryonic lethality in calreticulin-deficient mouse. J Biol Chem (2002) 1.14
Coping with endoplasmic reticulum stress in the cardiovascular system. Annu Rev Physiol (2012) 1.13
Identification of an N-domain histidine essential for chaperone function in calreticulin. J Biol Chem (2003) 1.12
Calreticulin enhances porcine wound repair by diverse biological effects. Am J Pathol (2008) 1.10
Identification by mutational analysis of amino acid residues essential in the chaperone function of calreticulin. J Biol Chem (2005) 1.10
Calreticulin, Ca2+, and calcineurin - signaling from the endoplasmic reticulum. Mol Cells (2004) 1.08
Higher plant calreticulins have acquired specialized functions in Arabidopsis. PLoS One (2010) 1.07
Neuroinflammation and endoplasmic reticulum stress are coregulated by crocin to prevent demyelination and neurodegeneration. J Immunol (2011) 1.05
Functional characterization of Arabidopsis calreticulin1a: a key alleviator of endoplasmic reticulum stress. Plant Cell Physiol (2008) 1.05
Polycystin-2 associates with tropomyosin-1, an actin microfilament component. J Mol Biol (2003) 1.04
Seasonal H1N1 influenza virus infection induces cross-protective pandemic H1N1 virus immunity through a CD8-independent, B cell-dependent mechanism. J Virol (2011) 1.03
Comparison of single versus booster dose of influenza vaccination on humoral and cellular immune responses in older adults. Vaccine (2005) 1.01
Calreticulin for better or for worse, in sickness and in health, until death do us part. Cell Calcium (2013) 1.01
Identification of a novel human granzyme B inhibitor secreted by cultured sertoli cells. J Immunol (2006) 1.00
Vesicle-associated membrane protein 7 (VAMP-7) is essential for target cell killing in a natural killer cell line. Biochem Biophys Res Commun (2007) 0.97
Calreticulin reveals a critical Ca(2+) checkpoint in cardiac myofibrillogenesis. J Cell Biol (2002) 0.97
Calnexin deficiency and endoplasmic reticulum stress-induced apoptosis. Biochemistry (2002) 0.97
Granzyme B degradation by autophagy decreases tumor cell susceptibility to natural killer-mediated lysis under hypoxia. Proc Natl Acad Sci U S A (2013) 0.96
Calnexin deficiency leads to dysmyelination. J Biol Chem (2010) 0.94
Calreticulin signals upstream of calcineurin and MEF2C in a critical Ca(2+)-dependent signaling cascade. J Cell Biol (2005) 0.94
Calreticulin affects fibronectin-based cell-substratum adhesion via the regulation of c-Src activity. J Biol Chem (2007) 0.93
Endoplasmic reticulum stress in the absence of calnexin. Cell Stress Chaperones (2008) 0.93
Retracted Calreticulin inhibits commitment to adipocyte differentiation. J Cell Biol (2008) 0.93
Suppressive roles of calreticulin in prostate cancer growth and metastasis. Am J Pathol (2009) 0.93
Embryonic stem cell-derived cardiomyogenesis: a novel role for calreticulin as a regulator. Stem Cells (2009) 0.93
Calcium-mediated perception and defense responses activated in plant cells by metabolite mixtures secreted by the biocontrol fungus Trichoderma atroviride. BMC Plant Biol (2007) 0.92
The granzyme B-serglycin complex from cytotoxic granules requires dynamin for endocytosis. Blood (2004) 0.92
Modulation of STIM1 and capacitative Ca2+ entry by the endoplasmic reticulum luminal oxidoreductase ERp57. EMBO Rep (2011) 0.92
Identification of the rheumatoid arthritis shared epitope binding site on calreticulin. PLoS One (2010) 0.92
The human host defense peptide LL-37 induces apoptosis in a calpain- and apoptosis-inducing factor-dependent manner involving Bax activity. Mol Cancer Res (2009) 0.91
Expansion and long-term maintenance of induced pluripotent stem cells in stirred suspension bioreactors. J Tissue Eng Regen Med (2011) 0.91
Cytoskeletal disassembly and cell rounding promotes adipogenesis from ES cells. Stem Cell Rev (2010) 0.91
Comparison of successful and unsuccessful islet/Sertoli cell cotransplant grafts in streptozotocin-induced diabetic mice. Cell Transplant (2008) 0.90
Granule-derived granzyme B mediates the vulnerability of human neurons to T cell-induced neurotoxicity. J Immunol (2011) 0.90
Calreticulin in the heart. Mol Cell Biochem (2004) 0.90
Overview of the role for calreticulin in the enhancement of wound healing through multiple biological effects. J Investig Dermatol Symp Proc (2006) 0.90
Endoplasmic reticulum stress during the embryonic development of the central nervous system in the mouse. Int J Dev Neurosci (2007) 0.90
Calreticulin induces dilated cardiomyopathy. PLoS One (2013) 0.90
Role of calnexin in the ER quality control and productive folding of CFTR; differential effect of calnexin knockout on wild-type and DeltaF508 CFTR. Biochim Biophys Acta (2008) 0.90
Endoplasmic and sarcoplasmic reticulum in the heart. Trends Cell Biol (2009) 0.89
Transcriptional control of the calreticulin gene in health and disease. Int J Biochem Cell Biol (2008) 0.89
Regulation of peripheral T cell activation by calreticulin. J Exp Med (2006) 0.89
Stem cell-based approaches to solving the problem of tissue supply for islet transplantation in type 1 diabetes. Int J Biochem Cell Biol (2004) 0.88
A novel mechanism of regulatory T cell-mediated down-regulation of autoimmunity. Int Immunol (2006) 0.88
Assembling pieces of the cardiac puzzle; calreticulin and calcium-dependent pathways in cardiac development, health, and disease. Trends Cardiovasc Med (2006) 0.88
Modulation of the tumor cell phenotype by IFN-gamma results in resistance of uveal melanoma cells to granule-mediated lysis by cytotoxic lymphocytes. J Immunol (2008) 0.88
Ultrastructural analysis of development of myocardium in calreticulin-deficient mice. BMC Dev Biol (2006) 0.88
Arrhythmia induced by spatiotemporal overexpression of calreticulin in the heart. Mol Genet Metab (2007) 0.87
Organellar calcium buffers. Cold Spring Harb Perspect Biol (2011) 0.87
Calreticulin in cardiac development and pathology. Biochim Biophys Acta (2002) 0.87