Published in Dev Biol on October 21, 2006
SUMO-specific protease 2 is essential for modulating p53-Mdm2 in development of trophoblast stem cell niches and lineages. PLoS Biol (2008) 2.35
Update on Wnt signaling in bone cell biology and bone disease. Gene (2011) 2.03
Reciprocal regulation of Wnt and Gpr177/mouse Wntless is required for embryonic axis formation. Proc Natl Acad Sci U S A (2009) 1.86
Gpr177, a novel locus for bone mineral density and osteoporosis, regulates osteogenesis and chondrogenesis in skeletal development. J Bone Miner Res (2013) 1.64
rBMP represses Wnt signaling and influences skeletal progenitor cell fate specification during bone repair. J Bone Miner Res (2010) 1.56
Microarray gene expression profiling of osteoarthritic bone suggests altered bone remodelling, WNT and transforming growth factor-beta/bone morphogenic protein signalling. Arthritis Res Ther (2007) 1.47
Beta-catenin/T-cell factor signaling is activated during lung injury and promotes the survival and migration of alveolar epithelial cells. J Biol Chem (2009) 1.35
Wnt signaling and injury repair. Cold Spring Harb Perspect Biol (2012) 1.30
Axin2 controls bone remodeling through the beta-catenin-BMP signaling pathway in adult mice. J Cell Sci (2009) 1.29
EphA4 as an effector of Twist1 in the guidance of osteogenic precursor cells during calvarial bone growth and in craniosynostosis. Development (2009) 1.26
Gpr177/mouse Wntless is essential for Wnt-mediated craniofacial and brain development. Dev Dyn (2011) 1.24
Wnt signaling and skeletal development. Cell Signal (2007) 1.22
FOXOs attenuate bone formation by suppressing Wnt signaling. J Clin Invest (2013) 1.21
Wnt signaling in bone development and disease: making stronger bone with Wnts. Cold Spring Harb Perspect Biol (2012) 1.18
The balance of WNT and FGF signaling influences mesenchymal stem cell fate during skeletal development. Sci Signal (2010) 1.16
Functional comparison of chronological and in vitro aging: differential role of the cytoskeleton and mitochondria in mesenchymal stromal cells. PLoS One (2012) 1.05
SUMO-specific protease 2 in Mdm2-mediated regulation of p53. Cell Death Differ (2010) 1.04
Augmentation of Smad-dependent BMP signaling in neural crest cells causes craniosynostosis in mice. J Bone Miner Res (2013) 1.01
Role of Wnt signaling in the biology of the periodontium. Dev Dyn (2010) 1.01
Expression of Gpr177, a Wnt trafficking regulator, in mouse embryogenesis. Dev Dyn (2010) 1.00
Co-opted JNK/SAPK signaling in Wnt/beta-catenin-induced tumorigenesis. Neoplasia (2008) 1.00
Manipulating gene activity in Wnt1-expressing precursors of neural epithelial and neural crest cells. Dev Dyn (2010) 0.99
Axin2 regulates chondrocyte maturation and axial skeletal development. J Orthop Res (2010) 0.97
β-catenin/cyclin D1 mediated development of suture mesenchyme in calvarial morphogenesis. BMC Dev Biol (2010) 0.96
Runx2 protein represses Axin2 expression in osteoblasts and is required for craniosynostosis in Axin2-deficient mice. J Biol Chem (2013) 0.94
Phospholipase C signaling via the parathyroid hormone (PTH)/PTH-related peptide receptor is essential for normal bone responses to PTH. Endocrinology (2010) 0.94
Sclerostin deficient mice rapidly heal bone defects by activating β-catenin and increasing intramembranous ossification. Biochem Biophys Res Commun (2013) 0.93
Augmenting endogenous Wnt signaling improves skin wound healing. PLoS One (2013) 0.92
Neural crest cell signaling pathways critical to cranial bone development and pathology. Exp Cell Res (2014) 0.91
Jagged1 functions downstream of Twist1 in the specification of the coronal suture and the formation of a boundary between osteogenic and non-osteogenic cells. Dev Biol (2010) 0.91
Differential expression of extracellular matrix-mediated pathways in single-suture craniosynostosis. PLoS One (2011) 0.89
Viable mice with compound mutations in the Wnt/Dvl pathway antagonists nkd1 and nkd2. Mol Cell Biol (2007) 0.89
Association of AXIN2 with non-syndromic oral clefts in multiple populations. J Dent Res (2012) 0.87
Disruption of SUMO-specific protease 2 induces mitochondria mediated neurodegeneration. PLoS Genet (2014) 0.87
Wnt signaling regulates homeostasis of the periodontal ligament. J Periodontal Res (2014) 0.87
Craniosynostosis of coronal suture in twist1 mice occurs through endochondral ossification recapitulating the physiological closure of posterior frontal suture. Front Physiol (2011) 0.85
Co-activator activator (CoAA) prevents the transcriptional activity of Runt domain transcription factors. J Cell Biochem (2009) 0.84
Gpr177 deficiency impairs mammary development and prohibits Wnt-induced tumorigenesis. PLoS One (2013) 0.82
Transcriptome correlation analysis identifies two unique craniosynostosis subtypes associated with IRS1 activation. Physiol Genomics (2012) 0.80
Extraembryonic but not embryonic SUMO-specific protease 2 is required for heart development. Sci Rep (2016) 0.79
Runx2 is required for early stages of endochondral bone formation but delays final stages of bone repair in Axin2-deficient mice. Bone (2014) 0.77
Axin2-expressing cells execute regeneration after skeletal injury. Sci Rep (2016) 0.77
Rap1b is an effector of Axin2 regulating crosstalk of signaling pathways during skeletal development. J Bone Miner Res (2017) 0.77
Loss of Axin2 Causes Ocular Defects During Mouse Eye Development. Invest Ophthalmol Vis Sci (2016) 0.76
Effects of thyroxine exposure on the Twist 1 +/- phenotype: A test of gene-environment interaction modeling for craniosynostosis. Birth Defects Res A Clin Mol Teratol (2016) 0.75
Signaling networks in joint development. Dev Dyn (2016) 0.75
Frontal Bone Insufficiency in Gsk3β Mutant Mice. PLoS One (2016) 0.75
Signaling mechanisms implicated in cranial sutures pathophysiology: Craniosynostosis. BBA Clin (2016) 0.75
Lithium chloride promotes neuronal differentiation of rat neural stem cells and enhances neural regeneration in Parkinson's disease model. Cytotechnology (2017) 0.75
BmpR1A is a major type 1 BMP receptor for BMP-Smad signaling during skull development. Dev Biol (2017) 0.75
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Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway. Mol Cell Biol (2002) 10.95
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Regulation of cadherin-mediated adhesion in morphogenesis. Nat Rev Mol Cell Biol (2005) 9.27
Inactivation of the beta-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development. Development (2001) 9.00
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Wnt/beta-catenin signaling in mesenchymal progenitors controls osteoblast and chondrocyte differentiation during vertebrate skeletogenesis. Dev Cell (2005) 8.16
Canonical Wnt signaling in differentiated osteoblasts controls osteoclast differentiation. Dev Cell (2005) 7.64
Canonical Wnt/beta-catenin signaling prevents osteoblasts from differentiating into chondrocytes. Dev Cell (2005) 6.90
A mutation in the LDL receptor-related protein 5 gene results in the autosomal dominant high-bone-mass trait. Am J Hum Genet (2001) 6.56
The mouse Fused locus encodes Axin, an inhibitor of the Wnt signaling pathway that regulates embryonic axis formation. Cell (1997) 6.10
Interactions between Sox9 and beta-catenin control chondrocyte differentiation. Genes Dev (2004) 4.78
Regulation of osteoblastogenesis and bone mass by Wnt10b. Proc Natl Acad Sci U S A (2005) 4.48
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FGF signaling pathways in endochondral and intramembranous bone development and human genetic disease. Genes Dev (2002) 4.16
Tissue origins and interactions in the mammalian skull vault. Dev Biol (2002) 3.95
A presenilin-1/gamma-secretase cleavage releases the E-cadherin intracellular domain and regulates disassembly of adherens junctions. EMBO J (2002) 3.87
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Epithelial Bmpr1a regulates differentiation and proliferation in postnatal hair follicles and is essential for tooth development. Development (2004) 3.46
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Identification of a domain of Axin that binds to the serine/threonine protein phosphatase 2A and a self-binding domain. J Biol Chem (1999) 2.38
Distinct molecular forms of beta-catenin are targeted to adhesive or transcriptional complexes. J Cell Biol (2004) 2.33
A Wnt canon orchestrating osteoblastogenesis. Trends Cell Biol (2006) 2.32
Distinct beta-catenins mediate adhesion and signalling functions in C. elegans. Nature (2000) 2.16
Dkk2 has a role in terminal osteoblast differentiation and mineralized matrix formation. Nat Genet (2005) 2.10
The BMP antagonist noggin regulates cranial suture fusion. Nature (2003) 2.09
beta-Catenin: a pivot between cell adhesion and Wnt signalling. Curr Biol (2005) 2.06
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Bone morphogenetic proteins induce the expression of noggin, which limits their activity in cultured rat osteoblasts. J Clin Invest (1998) 1.74
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Decisions, decisions: beta-catenin chooses between adhesion and transcription. Trends Cell Biol (2005) 1.66
Impaired mammary gland and lymphoid development caused by inducible expression of Axin in transgenic mice. J Cell Biol (2001) 1.59
Genetic interaction between Wnt/beta-catenin and BMP receptor signaling during formation of the AER and the dorsal-ventral axis in the limb. Genes Dev (2003) 1.55
Calcium influx triggers the sequential proteolysis of extracellular and cytoplasmic domains of E-cadherin, leading to loss of beta-catenin from cell-cell contacts. Oncogene (1999) 1.55
The transcription factor SOX9 regulates cell cycle and differentiation genes in chondrocytic CFK2 cells. J Biol Chem (2001) 1.51
Smad1, beta-catenin and Tcf4 associate in a molecular complex with the Myc promoter in dysplastic renal tissue and cooperate to control Myc transcription. Development (2004) 1.36
Development of a unique system for spatiotemporal and lineage-specific gene expression in mice. Proc Natl Acad Sci U S A (2005) 1.35
Impaired neural development caused by inducible expression of Axin in transgenic mice. Mech Dev (2006) 1.32
Targeted disruption of cadherin-11 leads to a reduction in bone density in calvaria and long bone metaphyses. J Bone Miner Res (2001) 1.16
Sox9 neural crest determinant gene controls patterning and closure of the posterior frontal cranial suture. Dev Biol (2005) 1.16
Two potentially oncogenic cyclins, cyclin A and cyclin D1, share common properties of subunit configuration, tyrosine phosphorylation and physical association with the Rb protein. Oncogene (1993) 1.12
Cell-cell interaction mediated by cadherin-11 directly regulates the differentiation of mesenchymal cells into the cells of the osteo-lineage and the chondro-lineage. J Bone Miner Res (2004) 1.03
Cell-cell interactions in regulating osteogenesis and osteoblast function. Birth Defects Res C Embryo Today (2005) 1.02
A role for N-cadherin in the development of the differentiated osteoblastic phenotype. J Bone Miner Res (2000) 1.00
Wnt/beta-catenin--a canonical tale of cell-fate choice in the vertebrate skeleton. Dev Cell (2005) 0.99
TGFbeta signaling at the summit. Development (2005) 0.83
Immunohistochemical analysis of the D-type cyclin-dependent kinases Cdk4 and Cdk6, using a series of monoclonal antibodies. Hybridoma (1999) 0.80
The role of Axin2 in calvarial morphogenesis and craniosynostosis. Development (2005) 2.63
SUMO-specific protease 2 is essential for modulating p53-Mdm2 in development of trophoblast stem cell niches and lineages. PLoS Biol (2008) 2.35
Sustained Neurog3 expression in hormone-expressing islet cells is required for endocrine maturation and function. Proc Natl Acad Sci U S A (2009) 2.09
Reciprocal regulation of Wnt and Gpr177/mouse Wntless is required for embryonic axis formation. Proc Natl Acad Sci U S A (2009) 1.86
Gpr177, a novel locus for bone mineral density and osteoporosis, regulates osteogenesis and chondrogenesis in skeletal development. J Bone Miner Res (2013) 1.64
Development of a unique system for spatiotemporal and lineage-specific gene expression in mice. Proc Natl Acad Sci U S A (2005) 1.35
Impaired neural development caused by inducible expression of Axin in transgenic mice. Mech Dev (2006) 1.32
Axin2 controls bone remodeling through the beta-catenin-BMP signaling pathway in adult mice. J Cell Sci (2009) 1.29
Gpr177/mouse Wntless is essential for Wnt-mediated craniofacial and brain development. Dev Dyn (2011) 1.24
The balance of WNT and FGF signaling influences mesenchymal stem cell fate during skeletal development. Sci Signal (2010) 1.16
Cartilage-specific β-catenin signaling regulates chondrocyte maturation, generation of ossification centers, and perichondrial bone formation during skeletal development. J Bone Miner Res (2012) 1.15
Epidermal Wnt controls hair follicle induction by orchestrating dynamic signaling crosstalk between the epidermis and dermis. J Invest Dermatol (2012) 1.13
Co-opted JNK/SAPK signaling in Wnt/beta-catenin-induced tumorigenesis. Neoplasia (2008) 1.00
Expression of Gpr177, a Wnt trafficking regulator, in mouse embryogenesis. Dev Dyn (2010) 1.00
Manipulating gene activity in Wnt1-expressing precursors of neural epithelial and neural crest cells. Dev Dyn (2010) 0.99
β-catenin/cyclin D1 mediated development of suture mesenchyme in calvarial morphogenesis. BMC Dev Biol (2010) 0.96
Intra-epithelial requirement of canonical Wnt signaling for tooth morphogenesis. J Biol Chem (2013) 0.94
Runx2 protein represses Axin2 expression in osteoblasts and is required for craniosynostosis in Axin2-deficient mice. J Biol Chem (2013) 0.94
Transgenic control of mitochondrial fission induces mitochondrial uncoupling and relieves diabetic oxidative stress. Diabetes (2012) 0.93
The inductive role of Wnt-β-Catenin signaling in the formation of oral apparatus. Dev Biol (2011) 0.90
Axin1 prevents Salmonella invasiveness and inflammatory response in intestinal epithelial cells. PLoS One (2012) 0.84
Gpr177 deficiency impairs mammary development and prohibits Wnt-induced tumorigenesis. PLoS One (2013) 0.82
Rapid and specific influenza virus detection by functionalized magnetic nanoparticles and mass spectrometry. J Nanobiotechnology (2011) 0.82
Gpr177 regulates pulmonary vasculature development. Development (2013) 0.81
Contributions of cation-π interactions to the collagen triple helix stability. Arch Biochem Biophys (2011) 0.80
Self-assembly of short collagen-related peptides into fibrils via cation-π interactions. Biochemistry (2011) 0.79
Derivation of mouse trophoblast stem cells from blastocysts. J Vis Exp (2010) 0.76