Published in Neuropsychopharmacology on November 29, 2006
Overexpression of Mineralocorticoid Receptors Partially Prevents Chronic Stress-Induced Reductions in Hippocampal Memory and Structural Plasticity. PLoS One (2015) 1.45
Mineralocorticoid receptor Iso/Val (rs5522) genotype moderates the association between previous childhood emotional neglect and amygdala reactivity. Am J Psychiatry (2012) 1.14
Genetics of cortisol secretion and depressive symptoms: a candidate gene and genome wide association approach. Psychoneuroendocrinology (2011) 1.03
Age-related declines in general cognitive abilities of Balb/C mice are associated with disparities in working memory, body weight, and general activity. Learn Mem (2008) 1.02
Neurogenetics of depression: a focus on reward processing and stress sensitivity. Neurobiol Dis (2012) 1.00
Associations between cognitive function and naturally occurring daily cortisol during middle adulthood: timing is everything. J Gerontol B Psychol Sci Soc Sci (2011) 0.99
11beta-hydroxysteroid dehydrogenase type 1 deficiency prevents memory deficits with aging by switching from glucocorticoid receptor to mineralocorticoid receptor-mediated cognitive control. J Neurosci (2011) 0.95
A randomized trial on mineralocorticoid receptor blockade in men: effects on stress responses, selective attention, and memory. Neuropsychopharmacology (2011) 0.94
The impact of mineralocorticoid receptor ISO/VAL genotype (rs5522) and stress on reward learning. Genes Brain Behav (2010) 0.92
A common and functional mineralocorticoid receptor haplotype enhances optimism and protects against depression in females. Transl Psychiatry (2011) 0.89
Perception of a naturalistic stressor interacts with 5-HTTLPR/rs25531 genotype and gender to impact reward responsiveness. Neuropsychobiology (2011) 0.86
The role of a mineralocorticoid receptor gene functional polymorphism in the symptom dimensions of persistent ADHD. Eur Arch Psychiatry Clin Neurosci (2012) 0.83
MR and GR functional SNPs may modulate tobacco smoking susceptibility. J Neural Transm (Vienna) (2013) 0.82
Amygdala functional connectivity, HPA axis genetic variation, and life stress in children and relations to anxiety and emotion regulation. J Abnorm Psychol (2015) 0.81
Does white matter structure or hippocampal volume mediate associations between cortisol and cognitive ageing? Psychoneuroendocrinology (2015) 0.80
HPA axis genetic variation, pubertal status, and sex interact to predict amygdala and hippocampus responses to negative emotional faces in school-age children. Neuroimage (2015) 0.79
Vulnerability to stroke: implications of perinatal programming of the hypothalamic-pituitary-adrenal axis. Front Behav Neurosci (2009) 0.79
Effects of Mineralocorticoid Receptor Overexpression on Anxiety and Memory after Early Life Stress in Female Mice. Front Behav Neurosci (2016) 0.76
Overexpression of mineralocorticoid receptors does not affect memory and anxiety-like behavior in female mice. Front Behav Neurosci (2015) 0.76
The cortisol awakening response and cognition across the adult lifespan. Brain Cogn (2016) 0.75
Early life adversity: Lasting consequences for emotional learning. Neurobiol Stress (2016) 0.75
Cortisol and cognitive function in midlife: the role of childhood cognition and educational attainment. Psychoneuroendocrinology (2014) 0.75
Overexpression of Mineralocorticoid Receptors in the Mouse Forebrain Partly Alleviates the Effects of Chronic Early Life Stress on Spatial Memory, Neurogenesis and Synaptic Function in the Dentate Gyrus. Front Cell Neurosci (2017) 0.75
HPA Axis Genes, and their Interaction with Childhood Maltreatment, are Related to Cortisol Levels and Stress-Related Phenotypes. Neuropsychopharmacology (2017) 0.75
Pravastatin in elderly individuals at risk of vascular disease (PROSPER): a randomised controlled trial. Lancet (2002) 17.19
Persistent epigenetic differences associated with prenatal exposure to famine in humans. Proc Natl Acad Sci U S A (2008) 8.39
Effect of 3-year folic acid supplementation on cognitive function in older adults in the FACIT trial: a randomised, double blind, controlled trial. Lancet (2007) 5.75
Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. Nat Genet (2012) 5.48
Thyroid status, disability and cognitive function, and survival in old age. JAMA (2004) 5.39
Subclinical hypothyroidism and the risk of coronary heart disease and mortality. JAMA (2010) 5.20
The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis. Lancet (2012) 4.87
DNA methylation differences after exposure to prenatal famine are common and timing- and sex-specific. Hum Mol Genet (2009) 4.25
Identification of seven loci affecting mean telomere length and their association with disease. Nat Genet (2013) 3.87
Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study. Lancet (2012) 3.48
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet (2012) 3.21
Measuring cognitive function with age: the influence of selection by health and survival. Epidemiology (2008) 3.19
Heritable rather than age-related environmental and stochastic factors dominate variation in DNA methylation of the human IGF2/H19 locus. Hum Mol Genet (2007) 3.06
Telomere length predicts survival independent of genetic influences. Aging Cell (2007) 3.01
Vitamin B12 and folate and the risk of anemia in old age: the Leiden 85-Plus Study. Arch Intern Med (2008) 2.90
Evidence of genetic enrichment for exceptional survival using a family approach: the Leiden Longevity Study. Eur J Hum Genet (2006) 2.89
Telomere length in white blood cells is not associated with morbidity or mortality in the oldest old: a population-based study. Aging Cell (2005) 2.83
Predicting survival in oldest old people. Am J Med (2012) 2.81
Variation in the human TP53 gene affects old age survival and cancer mortality. Exp Gerontol (2005) 2.81
Variation, patterns, and temporal stability of DNA methylation: considerations for epigenetic epidemiology. FASEB J (2010) 2.74
Different types of V(D)J recombination and end-joining defects in DNA double-strand break repair mutant mammalian cells. Eur J Immunol (2002) 2.57
Large-scale analysis of association between GDF5 and FRZB variants and osteoarthritis of the hip, knee, and hand. Arthritis Rheum (2009) 2.47
Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited. Aging Cell (2011) 2.37
Association of the interleukin-1 gene cluster with radiographic signs of osteoarthritis of the hip. Arthritis Rheum (2004) 2.33
Nonagenarian siblings and their offspring display lower risk of mortality and morbidity than sporadic nonagenarians: The Leiden Longevity Study. J Am Geriatr Soc (2009) 2.30
External validity of a trial comprised of elderly patients with hormone receptor-positive breast cancer. J Natl Cancer Inst (2014) 2.26
Subclinical hyperthyroidism and the risk of coronary heart disease and mortality. Arch Intern Med (2012) 2.24
Periconceptional maternal folic acid use of 400 microg per day is related to increased methylation of the IGF2 gene in the very young child. PLoS One (2009) 2.23
Regional frontal cortical volumes decrease differentially in aging: an MRI study to compare volumetric approaches and voxel-based morphometry. Neuroimage (2002) 2.19
Reduced insulin/IGF-1 signalling and human longevity. Aging Cell (2005) 2.13
Effect of anemia and comorbidity on functional status and mortality in old age: results from the Leiden 85-plus Study. CMAJ (2009) 2.11
Framingham stroke risk score and cognitive impairment for predicting first-time stroke in the oldest old. Stroke (2013) 2.10
In a population-based prospective study, no association between high blood pressure and mortality after age 85 years. J Hypertens (2006) 2.04
Handgrip strength and mortality in the oldest old population: the Leiden 85-plus study. CMAJ (2010) 2.03
Efficacy and toxicity of methotrexate in early rheumatoid arthritis are associated with single-nucleotide polymorphisms in genes coding for folate pathway enzymes. Arthritis Rheum (2006) 2.00
Association between age at diagnosis and disease-specific mortality among postmenopausal women with hormone receptor-positive breast cancer. JAMA (2012) 2.00
PASSion: a pattern growth algorithm-based pipeline for splice junction detection in paired-end RNA-Seq data. Bioinformatics (2012) 1.95
Systemic markers of inflammation and cognitive decline in old age. J Am Geriatr Soc (2007) 1.91
A meta-analysis of European and Asian cohorts reveals a global role of a functional SNP in the 5' UTR of GDF5 with osteoarthritis susceptibility. Hum Mol Genet (2008) 1.91
Rey's verbal learning test: normative data for 1855 healthy participants aged 24-81 years and the influence of age, sex, education, and mode of presentation. J Int Neuropsychol Soc (2005) 1.90
The continuing value of twin studies in the omics era. Nat Rev Genet (2012) 1.88
Genome-wide association study of smoking initiation and current smoking. Am J Hum Genet (2009) 1.87
Haplotypes in the human Foxo1a and Foxo3a genes; impact on disease and mortality at old age. Eur J Hum Genet (2007) 1.85
The epigenome: archive of the prenatal environment. Epigenetics (2009) 1.82
The Stroop color-word test: influence of age, sex, and education; and normative data for a large sample across the adult age range. Assessment (2006) 1.80
Handgrip strength as a predictor of functional, psychological and social health. A prospective population-based study among the oldest old. Age Ageing (2010) 1.79
Subclinical thyroid dysfunction and the risk of heart failure events: an individual participant data analysis from 6 prospective cohorts. Circulation (2012) 1.79
A voxel-based morphometric study to determine individual differences in gray matter density associated with age and cognitive change over time. Cereb Cortex (2004) 1.76
Deficits of memory, executive functioning and attention following infarction in the thalamus; a study of 22 cases with localised lesions. Neuropsychologia (2003) 1.76
Low production capacity of interleukin-10 associates with the metabolic syndrome and type 2 diabetes : the Leiden 85-Plus Study. Diabetes (2002) 1.75
Meta-analysis of genome-wide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22. Ann Rheum Dis (2010) 1.75
Meta-analysis of telomere length in 19,713 subjects reveals high heritability, stronger maternal inheritance and a paternal age effect. Eur J Hum Genet (2013) 1.72
Is there a side predilection for cerebrovascular disease? Hypertension (2003) 1.71
Low serum free triiodothyronine levels mark familial longevity: the Leiden Longevity Study. J Gerontol A Biol Sci Med Sci (2009) 1.70
High blood pressure and resilience to physical and cognitive decline in the oldest old: the Leiden 85-plus Study. J Am Geriatr Soc (2012) 1.70
Novel genetic variants associated with lumbar disc degeneration in northern Europeans: a meta-analysis of 4600 subjects. Ann Rheum Dis (2012) 1.66
Serum calcium and cognitive function in old age. J Am Geriatr Soc (2007) 1.66
Cigarette smoking and alcohol consumption in relation to cognitive performance in middle age. Am J Epidemiol (2002) 1.65
A meta-analysis of four genome-wide association studies of survival to age 90 years or older: the Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium. J Gerontol A Biol Sci Med Sci (2010) 1.65
The Netherlands Twin Register biobank: a resource for genetic epidemiological studies. Twin Res Hum Genet (2010) 1.65
Identification and systematic annotation of tissue-specific differentially methylated regions using the Illumina 450k array. Epigenetics Chromatin (2013) 1.62
Inflammation and interleukin-1 signaling network contribute to depressive symptoms but not cognitive decline in old age. Exp Gerontol (2007) 1.62
Genome-wide association study (GWAS)-identified disease risk alleles do not compromise human longevity. Proc Natl Acad Sci U S A (2010) 1.60
Identification of DIO2 as a new susceptibility locus for symptomatic osteoarthritis. Hum Mol Genet (2008) 1.60
Adipocytokines and risk of stroke in older people: a nested case-control study. Int J Epidemiol (2008) 1.59
The inverse relationship between alanine aminotransferase in the normal range and adverse cardiovascular and non-cardiovascular outcomes. Int J Epidemiol (2011) 1.58
What accounts for the wide variation in life span of genetically identical organisms reared in a constant environment? Mech Ageing Dev (2005) 1.57
Epigenetic variation during the adult lifespan: cross-sectional and longitudinal data on monozygotic twin pairs. Aging Cell (2012) 1.55
Are markers of inflammation more strongly associated with risk for fatal than for nonfatal vascular events? PLoS Med (2009) 1.54
Genes encoding longevity: from model organisms to humans. Aging Cell (2008) 1.53
Neuromyths in Education: Prevalence and Predictors of Misconceptions among Teachers. Front Psychol (2012) 1.52
Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. PLoS Genet (2013) 1.52
Heritabilities of apolipoprotein and lipid levels in three countries. Twin Res (2002) 1.50
Accuracy of direct segmental multi-frequency bioimpedance analysis in the assessment of total body and segmental body composition in middle-aged adult population. Clin Nutr (2011) 1.50
The Adult Netherlands Twin Register: twenty-five years of survey and biological data collection. Twin Res Hum Genet (2013) 1.49
Serotonergic modulation of prefrontal cortex during negative feedback in probabilistic reversal learning. Neuropsychopharmacology (2005) 1.49
Old age mortality and macroeconomic cycles. J Epidemiol Community Health (2013) 1.48
Pravastatin and cognitive function in the elderly. Results of the PROSPER study. J Neurol (2009) 1.47
Change in sensory functioning predicts change in cognitive functioning: results from a 6-year follow-up in the maastricht aging study. J Am Geriatr Soc (2005) 1.46