Published in Arch Intern Med on December 12, 2006
Cardiac troponin level elevations not related to acute coronary syndromes. Nat Rev Cardiol (2013) 1.71
Cardiac ischemia in patients with septic shock randomized to vasopressin or norepinephrine. Crit Care (2013) 1.46
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Effects of computerized clinical decision support systems on practitioner performance and patient outcomes: a systematic review. JAMA (2005) 23.44
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Vasopressin versus norepinephrine infusion in patients with septic shock. N Engl J Med (2008) 11.00
Comparison of low-intensity warfarin therapy with conventional-intensity warfarin therapy for long-term prevention of recurrent venous thromboembolism. N Engl J Med (2003) 8.55
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CONSORT 2010 Explanation and Elaboration: Updated guidelines for reporting parallel group randomised trials. J Clin Epidemiol (2010) 7.04
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High-frequency oscillation in early acute respiratory distress syndrome. N Engl J Med (2013) 6.56
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Comparison of mortality between private for-profit and private not-for-profit hemodialysis centers: a systematic review and meta-analysis. JAMA (2002) 5.57
An official ATS statement: grading the quality of evidence and strength of recommendations in ATS guidelines and recommendations. Am J Respir Crit Care Med (2006) 5.29
A Trial of Wound Irrigation in the Initial Management of Open Fracture Wounds. N Engl J Med (2015) 5.28
Treatment and outcomes of acute coronary syndromes in India (CREATE): a prospective analysis of registry data. Lancet (2008) 5.27
A systematic review and meta-analysis of studies comparing mortality rates of private for-profit and private not-for-profit hospitals. CMAJ (2002) 4.84
Dalteparin versus unfractionated heparin in critically ill patients. N Engl J Med (2011) 4.59
Association between postoperative troponin levels and 30-day mortality among patients undergoing noncardiac surgery. JAMA (2012) 4.58
Association between industry funding and statistically significant pro-industry findings in medical and surgical randomized trials. CMAJ (2004) 4.53
Andexanet Alfa for the Reversal of Factor Xa Inhibitor Activity. N Engl J Med (2015) 4.50
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Off-pump or on-pump coronary-artery bypass grafting at 30 days. N Engl J Med (2012) 4.32
Effects of off-pump and on-pump coronary-artery bypass grafting at 1 year. N Engl J Med (2013) 4.27
An observational study of orthopaedic abstracts and subsequent full-text publications. J Bone Joint Surg Am (2002) 4.25
Fluid resuscitation in sepsis: a systematic review and network meta-analysis. Ann Intern Med (2014) 3.96
A new 'mechanistic-practical" framework for designing and interpreting randomized trials. J Clin Epidemiol (2008) 3.75
The safety of addition of nitrous oxide to general anaesthesia in at-risk patients having major non-cardiac surgery (ENIGMA-II): a randomised, single-blind trial. Lancet (2014) 3.70
Physicians' and patients' choices in evidence based practice. BMJ (2002) 3.57
CONSORT 2010 explanation and elaboration: updated guidelines for reporting parallel group randomised trials. Int J Surg (2011) 3.57
GRADE guidelines 6. Rating the quality of evidence--imprecision. J Clin Epidemiol (2011) 3.54
The effect of selenium therapy on mortality in patients with sepsis syndrome: a systematic review and meta-analysis of randomized controlled trials. Crit Care Med (2013) 3.43
Family satisfaction with care in the intensive care unit: results of a multiple center study. Crit Care Med (2002) 3.36
Barriers to full-text publication following presentation of abstracts at annual orthopaedic meetings. J Bone Joint Surg Am (2003) 3.36
Meta-analysis: anticoagulant prophylaxis to prevent symptomatic venous thromboembolism in hospitalized medical patients. Ann Intern Med (2007) 3.33
Patients at the center: in our practice, and in our use of language. ACP J Club (2004) 3.32
Cardiac Complications in Patients Undergoing Major Noncardiac Surgery. N Engl J Med (2015) 3.31
Randomized controlled trials of surgical interventions. Ann Surg (2010) 3.30
Outcomes of patients treated with noninvasive ventilation by a medical emergency team on the wards. Respir Care (2013) 3.28
Quality of care in for-profit and not-for-profit nursing homes: systematic review and meta-analysis. BMJ (2009) 3.22
Risk of thromboembolism, recurrent hemorrhage, and death after warfarin therapy interruption for gastrointestinal tract bleeding. Arch Intern Med (2012) 3.16
Intensive care unit quality improvement: a "how-to" guide for the interdisciplinary team. Crit Care Med (2006) 3.15
Internal fixation compared with arthroplasty for displaced fractures of the femoral neck. A meta-analysis. J Bone Joint Surg Am (2003) 3.14
Effect of early surgery after hip fracture on mortality and complications: systematic review and meta-analysis. CMAJ (2010) 3.13
Patient and healthcare professional factors influencing end-of-life decision-making during critical illness: a systematic review. Crit Care Med (2011) 3.07
Problems with use of composite end points in cardiovascular trials: systematic review of randomised controlled trials. BMJ (2007) 3.06
Canadian survey of the use of sedatives, analgesics, and neuromuscular blocking agents in critically ill patients. Crit Care Med (2006) 3.06
Systematic review: efficacy and safety of rituximab for adults with idiopathic thrombocytopenic purpura. Ann Intern Med (2007) 2.97
Methodologic issues in systematic reviews and meta-analyses. Clin Orthop Relat Res (2003) 2.90
Rationing critical care beds: a systematic review. Crit Care Med (2004) 2.86
The efficacy and safety of heparin in patients with sepsis: a systematic review and metaanalysis. Crit Care Med (2015) 2.85
Interaction of vasopressin infusion, corticosteroid treatment, and mortality of septic shock. Crit Care Med (2009) 2.77
Payments for care at private for-profit and private not-for-profit hospitals: a systematic review and meta-analysis. CMAJ (2004) 2.76
Credibility of claims of subgroup effects in randomised controlled trials: systematic review. BMJ (2012) 2.69
Specific instructions for estimating unclearly reported blinding status in randomized trials were reliable and valid. J Clin Epidemiol (2011) 2.69
Early mobilisation for patients following acute myocardiac infarction: a systematic review and meta-analysis of experimental studies. Int J Nurs Stud (2009) 2.69
Operative management of displaced femoral neck fractures in elderly patients. An international survey. J Bone Joint Surg Am (2005) 2.68
End-of-life care for the critically ill: A national intensive care unit survey. Crit Care Med (2006) 2.61
Internet versus mailed questionnaires: a controlled comparison (2). J Med Internet Res (2004) 2.59
Angiopoietin-1 and angiopoietin-2 as clinically informative prognostic biomarkers of morbidity and mortality in severe sepsis. Crit Care Med (2011) 2.59
Clinical expertise in the era of evidence-based medicine and patient choice. ACP J Club (2002) 2.58
An observational study found that authors of randomized controlled trials frequently use concealment of randomization and blinding, despite the failure to report these methods. J Clin Epidemiol (2004) 2.58
Is a pre-operative brain natriuretic peptide or N-terminal pro-B-type natriuretic peptide measurement an independent predictor of adverse cardiovascular outcomes within 30 days of noncardiac surgery? A systematic review and meta-analysis of observational studies. J Am Coll Cardiol (2009) 2.56
Users' guide to detecting misleading claims in clinical research reports. BMJ (2004) 2.55
Age of transfused blood in critically ill adults. N Engl J Med (2015) 2.52
Management of antiphospholipid antibody syndrome: a systematic review. JAMA (2006) 2.47
Oral decontamination for prevention of pneumonia in mechanically ventilated adults: systematic review and meta-analysis. BMJ (2007) 2.44
Randomized clinical trials--removing unnecessary obstacles. N Engl J Med (2013) 2.43
Meta-analysis: low-molecular-weight heparin and bleeding in patients with severe renal insufficiency. Ann Intern Med (2006) 2.40
The quality of randomized trial reporting in leading medical journals since the revised CONSORT statement. Contemp Clin Trials (2005) 2.40
The design and interpretation of pilot trials in clinical research in critical care. Crit Care Med (2009) 2.38
Effect of nitric oxide on oxygenation and mortality in acute lung injury: systematic review and meta-analysis. BMJ (2007) 2.33
Can trial sequential monitoring boundaries reduce spurious inferences from meta-analyses? Int J Epidemiol (2008) 2.31
Surgery for hip fractures: Does surgical delay affect outcomes? Indian J Orthop (2011) 2.30
Mortality predictions in the intensive care unit: comparing physicians with scoring systems. Crit Care Med (2006) 2.29
Advance targeted transfusion in anemic cardiac surgical patients for kidney protection: an unblinded randomized pilot clinical trial. Anesthesiology (2012) 2.29
Written informed consent and selection bias in observational studies using medical records: systematic review. BMJ (2009) 2.27