Published in Science on November 07, 2008
Clocks not winding down: unravelling circadian networks. Nat Rev Mol Cell Biol (2010) 2.95
Development of the circadian oscillator during differentiation of mouse embryonic stem cells in vitro. Proc Natl Acad Sci U S A (2010) 1.34
Heritable circadian period length in a wild bird population. Proc Biol Sci (2010) 1.06
Genetic correlations and the evolution of photoperiodic time measurement within a local population of the pitcher-plant mosquito, Wyeomyia smithii. Heredity (Edinb) (2011) 1.01
Conserved role of unc-79 in ethanol responses in lightweight mutant mice. PLoS Genet (2010) 1.00
Manipulating the sleep-wake cycle and circadian rhythms to improve clinical management of major depression. BMC Med (2013) 0.99
Ras-mediated deregulation of the circadian clock in cancer. PLoS Genet (2014) 0.97
Genetic dissection of neural circuits and behavior in Mus musculus. Adv Genet (2009) 0.91
Homeostastic and non-homeostatic functions of melanocortin-3 receptors in the control of energy balance and metabolism. Physiol Behav (2011) 0.88
Circadian dysfunction may be a key component of the non-motor symptoms of Parkinson's disease: insights from a transgenic mouse model. Exp Neurol (2013) 0.87
Second-generation high-throughput forward genetic screen in mice to isolate subtle behavioral mutants. Proc Natl Acad Sci U S A (2011) 0.84
Forward-genetics analysis of sleep in randomly mutagenized mice. Nature (2016) 0.83
Drosophila melanogaster as a model for lead neurotoxicology and toxicogenomics research. Front Genet (2012) 0.81
The co-evolution of fairness preferences and costly punishment. PLoS One (2013) 0.80
Chronobiological Effects on Obesity. Curr Obes Rep (2012) 0.79
Phenotypic instability between the near isogenic substrains BALB/cJ and BALB/cByJ. Mamm Genome (2014) 0.79
Circadian dysfunction in response to in vivo treatment with the mitochondrial toxin 3-nitropropionic acid. ASN Neuro (2014) 0.78
Does the precision of a biological clock depend upon its period? Effects of the duper and tau mutations in Syrian hamsters. PLoS One (2012) 0.78
Signaling of pigment-dispersing factor (PDF) in the Madeira cockroach Rhyparobia maderae. PLoS One (2014) 0.77
Identification of mutations through dominant screening for obesity using C57BL/6 substrains. Sci Rep (2016) 0.77
Functional Implications of the CLOCK 3111T/C Single-Nucleotide Polymorphism. Front Psychiatry (2016) 0.75
Titanium biomaterials with complex surfaces induced aberrant peripheral circadian rhythms in bone marrow mesenchymal stromal cells. PLoS One (2017) 0.75
Two sides of a coin: ecological and chronobiological perspectives of timing in the wild. Philos Trans R Soc Lond B Biol Sci (2017) 0.75
Next-generation DNA sequencing methods. Annu Rev Genomics Hum Genet (2008) 68.81
Genome-wide in situ exon capture for selective resequencing. Nat Genet (2007) 19.97
Direct selection of human genomic loci by microarray hybridization. Nat Methods (2007) 17.73
PERIOD2::LUCIFERASE real-time reporting of circadian dynamics reveals persistent circadian oscillations in mouse peripheral tissues. Proc Natl Acad Sci U S A (2004) 12.43
The molecular biology of memory storage: a dialogue between genes and synapses. Science (2001) 11.85
Contributions of the amygdala to emotion processing: from animal models to human behavior. Neuron (2005) 10.49
A mouse for all reasons. Cell (2007) 9.01
Clock mutants of Drosophila melanogaster. Proc Natl Acad Sci U S A (1971) 8.63
Mutagenesis and mapping of a mouse gene, Clock, essential for circadian behavior. Science (1994) 7.83
Positional cloning of the mouse circadian clock gene. Cell (1997) 7.79
The genetics of mammalian circadian order and disorder: implications for physiology and disease. Nat Rev Genet (2008) 7.65
Circadian rhythms from multiple oscillators: lessons from diverse organisms. Nat Rev Genet (2005) 6.87
A sequence-based variation map of 8.27 million SNPs in inbred mouse strains. Nature (2007) 6.77
Circadian gene expression in individual fibroblasts: cell-autonomous and self-sustained oscillators pass time to daughter cells. Cell (2004) 6.44
Strategies for mapping and cloning quantitative trait genes in rodents. Nat Rev Genet (2005) 5.57
Positional syntenic cloning and functional characterization of the mammalian circadian mutation tau. Science (2000) 4.94
Genetic identification of Mom-1, a major modifier locus affecting Min-induced intestinal neoplasia in the mouse. Cell (1993) 4.66
Bioluminescence imaging of individual fibroblasts reveals persistent, independently phased circadian rhythms of clock gene expression. Curr Biol (2004) 4.49
Circadian oscillation of a mammalian homologue of the Drosophila period gene. Nature (1997) 4.44
The roads from phenotypic variation to gene discovery: mutagenesis versus QTLs. Nat Genet (2000) 4.28
Circadian mutant Overtime reveals F-box protein FBXL3 regulation of cryptochrome and period gene expression. Cell (2007) 3.99
The mouse as a model for human biology: a resource guide for complex trait analysis. Nat Rev Genet (2007) 3.55
RIGUI, a putative mammalian ortholog of the Drosophila period gene. Cell (1997) 3.24
Genome-wide epistatic interaction analysis reveals complex genetic determinants of circadian behavior in mice. Genome Res (2001) 3.04
Genetic dissection of behavior. Sci Am (1973) 2.93
CLOCK and NPAS2 have overlapping roles in the suprachiasmatic circadian clock. Nat Neurosci (2007) 2.84
Setting clock speed in mammals: the CK1 epsilon tau mutation in mice accelerates circadian pacemakers by selectively destabilizing PERIOD proteins. Neuron (2008) 2.65
Distinct components of spatial learning revealed by prior training and NMDA receptor blockade. Nature (1995) 2.47
Forward and reverse genetic approaches to behavior in the mouse. Science (1994) 2.20
The suprachiasmatic nucleus: a 25-year retrospective. J Biol Rhythms (1998) 2.03
The mouse Clock mutation behaves as an antimorph and maps within the W19H deletion, distal of Kit. Genetics (1997) 1.75
ENU mutagenesis, a way forward to understand gene function. Annu Rev Genomics Hum Genet (2008) 1.59
Finding new clock components: past and future. J Biol Rhythms (2004) 1.50
Physiology and biochemistry of Drosophila learning mutants. Physiol Rev (1996) 1.47
Sequence-based analysis of mutagenized mice. Mamm Genome (2000) 1.22
Trends in large-scale mouse mutagenesis: from genetics to functional genomics. Nat Rev Genet (2008) 1.21
Methods to record circadian rhythm wheel running activity in mice. Methods Enzymol (2005) 1.20
Intravenous drug self-administration in mice: practical considerations. Behav Genet (2006) 1.20
The art and design of genetic screens: mouse. Nat Rev Genet (2005) 1.08
Large-scale mutagenesis and phenotypic screens for the nervous system and behavior in mice. Trends Neurosci (2006) 1.01
A high through-put reverse genetic screen identifies two genes involved in remote memory in mice. PLoS One (2008) 0.99
Precision of the pacemaker nucleus in a weakly electric fish: network versus cellular influences. J Neurophysiol (2000) 0.96
PERIOD2::LUCIFERASE real-time reporting of circadian dynamics reveals persistent circadian oscillations in mouse peripheral tissues. Proc Natl Acad Sci U S A (2004) 12.43
The Collaborative Cross, a community resource for the genetic analysis of complex traits. Nat Genet (2004) 9.37
Transcriptional architecture and chromatin landscape of the core circadian clock in mammals. Science (2012) 4.77
Circadian mutant Overtime reveals F-box protein FBXL3 regulation of cryptochrome and period gene expression. Cell (2007) 3.99
The nature and identification of quantitative trait loci: a community's view. Nat Rev Genet (2003) 3.96
Gene set enrichment in eQTL data identifies novel annotations and pathway regulators. PLoS Genet (2008) 2.32
Falciparum malaria presenting as subdural hematoma. J Assoc Physicians India (2011) 2.24
Genomewide association analysis in diverse inbred mice: power and population structure. Genetics (2007) 2.01
Sex- and lineage-specific inheritance of depression-like behavior in the rat. Mamm Genome (2004) 1.99
Rhythmic PER abundance defines a critical nodal point for negative feedback within the circadian clock mechanism. Mol Cell (2009) 1.79
CKIepsilon/delta-dependent phosphorylation is a temperature-insensitive, period-determining process in the mammalian circadian clock. Proc Natl Acad Sci U S A (2009) 1.73
Competing E3 ubiquitin ligases govern circadian periodicity by degradation of CRY in nucleus and cytoplasm. Cell (2013) 1.56
Evidence of nanobacterial-like structures in calcified human arteries and cardiac valves. Am J Physiol Heart Circ Physiol (2004) 1.55
Circadian clock genes contribute to the regulation of hair follicle cycling. PLoS Genet (2009) 1.49
Generation, identification and functional characterization of the nob4 mutation of Grm6 in the mouse. Vis Neurosci (2007) 1.27
Cwp84, a surface-associated cysteine protease, plays a role in the maturation of the surface layer of Clostridium difficile. J Biol Chem (2009) 1.25
Uncovering the genetic landscape for multiple sleep-wake traits. PLoS One (2009) 1.21
Brain and muscle Arnt-like protein-1 (BMAL1) controls circadian cell proliferation and susceptibility to UVB-induced DNA damage in the epidermis. Proc Natl Acad Sci U S A (2012) 1.19
A fatal combo of dengue shock syndrome with acute subdural hematoma. Neurol India (2012) 1.10
Coronary artery to left ventricle fistula. Cardiovasc Ultrasound (2005) 1.09
Human-derived nanoparticles and vascular response to injury in rabbit carotid arteries: proof of principle. Int J Nanomedicine (2008) 1.08
Retromolar tracheal tube positioning for patients undergoing faciomaxillary surgery. Can J Anaesth (2005) 1.07
X-linked and lineage-dependent inheritance of coping responses to stress. Mamm Genome (2003) 1.06
Cell surface engineering with polyelectrolyte multilayer thin films. J Am Chem Soc (2011) 1.03
Results from screening over 9000 mutation-bearing mice for defects in the electroretinogram and appearance of the fundus. Vision Res (2004) 1.02
Multi-walled carbon nanotubes induce oxidative stress and apoptosis in human lung cancer cell line-A549. Nanotoxicology (2010) 1.01
Search for microbial signatures within human and microbial calcifications using soft x-ray spectromicroscopy. J Investig Med (2006) 1.01
Betulinic acid derivatives as anticancer agents: structure activity relationship. Anticancer Agents Med Chem (2006) 1.00
Monocrotophos induced apoptosis in PC12 cells: role of xenobiotic metabolizing cytochrome P450s. PLoS One (2011) 1.00
Association of glutathione S-transferase M1 and T1 gene polymorphism with oxidative stress in diabetic and nondiabetic chronic kidney disease. Ren Fail (2010) 0.98
Usf1, a suppressor of the circadian Clock mutant, reveals the nature of the DNA-binding of the CLOCK:BMAL1 complex in mice. Elife (2013) 0.98
CSA and CSB proteins interact with p53 and regulate its Mdm2-dependent ubiquitination. Cell Cycle (2011) 0.96
Muehrcke lines. CMAJ (2012) 0.96
Involvement of neurokinin receptors in the control of pulsatile luteinizing hormone secretion in rats. J Reprod Dev (2011) 0.94
A Mediterranean-style low-glycemic-load diet improves variables of metabolic syndrome in women, and addition of a phytochemical-rich medical food enhances benefits on lipoprotein metabolism. J Clin Lipidol (2011) 0.92
Interpretation of the mouse electroretinogram. Doc Ophthalmol (2007) 0.92
Generation, characterization, and molecular cloning of the Noerg-1 mutation of rhodopsin in the mouse. Vis Neurosci (2005) 0.91
Antimicrobial screening of ethnobotanically important stem bark of medicinal plants. Pharmacognosy Res (2010) 0.90
Genetic analysis of daily physical activity using a mouse chromosome substitution strain. Physiol Genomics (2009) 0.89
trans-Resveratrol protects ischemic PC12 Cells by inhibiting the hypoxia associated transcription factors and increasing the levels of antioxidant defense enzymes. ACS Chem Neurosci (2012) 0.89
Lineage is an epigenetic modifier of QTL influencing behavioral coping with stress. Behav Genet (2005) 0.88
A rare case of Cytomegalovirus, Scedosporium apiospermum and Mycobacterium tuberculosis in a renal transplant recipient. BMC Infect Dis (2014) 0.88
Ischemic insult induced apoptotic changes in PC12 cells: protection by trans resveratrol. Eur J Pharmacol (2011) 0.87
Genetic analysis of the stress-responsive adrenocortical axis. Physiol Genomics (2006) 0.87
Incidence and recognition of elevated triage blood pressure in the pediatric emergency department. Pediatr Emerg Care (2011) 0.87
Expression and inducibility of cytochrome P450s (CYP1A1, 2B6, 2E1, 3A4) in human cord blood CD34(+) stem cell-derived differentiating neuronal cells. Toxicol Sci (2012) 0.86
Identification of genetic loci involved in diabetes using a rat model of depression. Mamm Genome (2009) 0.86
Epidemiology of Clostridium difficile-associated disease (CDAD): a shift from hospital-acquired infection to long-term care facility-based infection. Dig Dis Sci (2013) 0.86
Comparison of measured and calculated bicarbonate values. Clin Chem (2008) 0.85
DNA damage and cholinesterase activity in occupational workers exposed to pesticides. Environ Toxicol Pharmacol (2010) 0.85
Chemical class rotations for control of Bemisia tabaci (Hemiptera: Aleyrodidae) on poinsettia and their effect on cryptic species population composition. Pest Manag Sci (2014) 0.85
Homology modeling and atomic level binding study of Leishmania MAPK with inhibitors. J Mol Model (2009) 0.85
Polymorphism in CYP1A1, GSTMI, GSTT1 genes and organochlorine pesticides in the etiology of hypospadias. Hum Exp Toxicol (2011) 0.84
Genetic suppression of the circadian Clock mutation by the melatonin biosynthesis pathway. Proc Natl Acad Sci U S A (2010) 0.83
Polymorphism in apolipoprotein E among migraineurs and tension-type headache subjects. J Headache Pain (2009) 0.83
Primary skin grafting in ear lobule keloid. Plast Reconstr Surg (2004) 0.82
Role of HSP27 and reduced glutathione in modulating malathion-induced apoptosis of human peripheral blood mononuclear cells: ameliorating effect of N-acetylcysteine and curcumin. Toxicol In Vitro (2009) 0.82
Comparative analysis of fecal fat quantitation via nuclear magnetic resonance spectroscopy (1H NMR) and gravimetry. Clin Chim Acta (2008) 0.82
Paraoxonase-1 genetic polymorphisms and susceptibility to DNA damage in workers occupationally exposed to organophosphate pesticides. Toxicol Appl Pharmacol (2011) 0.81
Effect of GSTM1 and GSTT1 double deletions in the development of oxidative stress in diabetic nephropathy patients. Indian J Biochem Biophys (2010) 0.81
Systemic inflammation and its response to treatment in patients with asthma. Respir Care (2011) 0.81
Pkb/Akt1 mediates Wnt/GSK3β/β-catenin signaling-induced apoptosis in human cord blood stem cells exposed to organophosphate pesticide monocrotophos. Stem Cells Dev (2012) 0.81
Prenatal loud music and noise: differential impact on physiological arousal, hippocampal synaptogenesis and spatial behavior in one day-old chicks. PLoS One (2013) 0.81
Covalent functionalized self-assembled lipo-polymerosome bearing amphotericin B for better management of leishmaniasis and its toxicity evaluation. Mol Pharm (2014) 0.81
Clinical predictors of fulminant colitis in patients with Clostridium difficile infection. Saudi J Gastroenterol (2012) 0.80
Cannabis smoking and acute coronary syndrome: two illustrative cases. Int J Cardiol (2007) 0.79
Adsorption of diethylchlorophosphate on metal oxide nanoparticles under static conditions. J Hazard Mater (2010) 0.79
Genetic polymorphisms of GSTM1, GSTT1 and GSTP1 and susceptibility to DNA damage in workers occupationally exposed to organophosphate pesticides. Mutat Res (2011) 0.79
Renal cell adaptation to oxalate. Urol Res (2005) 0.79
Differentiating neurons derived from human umbilical cord blood stem cells work as a test system for developmental neurotoxicity. Mol Neurobiol (2014) 0.79
Correction of the nose in patients with unilateral cleft lip with composite grafts. Scand J Plast Reconstr Surg Hand Surg (2005) 0.79
Solid Phase Synthesis and Application of Labeled Peptide Derivatives: Probes of Receptor-Opioid Peptide Interactions. Int J Pept Res Ther (2008) 0.78
Renal disease in patients infected with hepatitis B virus. Trop Gastroenterol (2016) 0.78
Polymorphisms in the P450 c17 (17-hydroxylase/17, 20-Lyase) gene: association with estradiol and testosterone concentration in hypospadias. Urology (2011) 0.78
Sturge Weber syndrome. J Assoc Physicians India (2011) 0.78
Genetic interactions between chromosomes 11 and 18 contribute to airway hyperresponsiveness in mice. PLoS One (2012) 0.78
Beta-thalassemia, hyperlipoproteinemia(a), and metabolic syndrome: its low-cost holistic therapy. J Altern Complement Med (2007) 0.78
Genetic polymorphism of glutathione S-transferase M1 and T1 in Delhi population of Northern India. Environ Toxicol Pharmacol (2009) 0.78
A preliminary study on the influence of glutathione S transferase T1 (GSTT1) as a risk factor for late onset Alzheimer's disease in North Indian population. Asian J Psychiatr (2012) 0.77
Protective effects of different antioxidants against endosulfan-induced oxidative stress and immunotoxicity in albino rats. Indian J Exp Biol (2009) 0.77
Synthesis, biological evaluation and molecular docking studies of stellatin derivatives as cyclooxygenase (COX-1, COX-2) inhibitors and anti-inflammatory agents. Bioorg Med Chem Lett (2011) 0.77
Epidermal stem cells ride the circadian wave. Genome Biol (2013) 0.77
A TEMPLATE-BASED FABRICATION TECHNIQUE FOR SPATIALLY-DESIGNED POLYMER MICRO/NANOFIBER COMPOSITES. Dig Tech Papers (2009) 0.77
Chlorine gas sensors using one-dimensional tellurium nanostructures. Talanta (2008) 0.77
Gene-environment interactions in a mutant mouse kindred with native airway constrictor hyperresponsiveness. Mamm Genome (2008) 0.77
Influence of CYP2C9, GSTM1, GSTT1 and NAT2 genetic polymorphisms on DNA damage in workers occupationally exposed to organophosphate pesticides. Mutat Res (2011) 0.77
Testicular toxicity induced by a triple neurokinin receptor antagonist in male dogs. Reprod Toxicol (2010) 0.77
Role of genetic polymorphisms of CYP1A1, CYP3A5, CYP2C9, CYP2D6, and PON1 in the modulation of DNA damage in workers occupationally exposed to organophosphate pesticides. Toxicol Appl Pharmacol (2011) 0.77
Homology modeling, molecular dynamics and inhibitor binding study on MurD ligase of Mycobacterium tuberculosis. Interdiscip Sci (2013) 0.76
Tumor suppression by resistant maltodextrin, Fibersol-2. Cancer Biol Ther (2015) 0.76
The destruction of the lower urinary tract by ketamine abuse: a new syndrome? BJU Int (2008) 0.76
Mammalian sperm capacitation: role of phosphotyrosine proteins. Soc Reprod Fertil Suppl (2007) 0.76
Novel Analogues of (R)-5-(Methylamino)-5,6-dihydro-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one (Sumanirole) Provide Clues to Dopamine D2/D3 Receptor Agonist Selectivity. J Med Chem (2016) 0.76
Thyroid hormones stimulate Na+-Pi transport activity in rat renal brush-border membranes: role of membrane lipid composition and fluidity. Mol Cell Biochem (2005) 0.76
MEMS-assisted spatially homogeneous endothelialization of a high length-to-depth aspect ratio microvascular network. Conf Proc IEEE Eng Med Biol Soc (2011) 0.76
Protective effects of L-pGlu-(2-propyl)-L-His-L-ProNH2, a newer thyrotropin releasing hormone analog in in vitro and in vivo models of cerebral ischemia. Peptides (2011) 0.76
Exploitation of lectinized lipo-polymerosome encapsulated Amphotericin B to target macrophages for effective chemotherapy of visceral leishmaniasis. Bioconjug Chem (2014) 0.76
Historical control data on developmental toxicity studies in rodents. Congenit Anom (Kyoto) (2014) 0.75
Historical control data on prenatal developmental toxicity studies in rabbits. Congenit Anom (Kyoto) (2012) 0.75