PubRank

David Meyre

Author PubWeight™ 227.82‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A genome-wide association study identifies novel risk loci for type 2 diabetes. Nature 2007 35.08
2 Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet 2010 23.08
3 New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet 2010 17.89
4 Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet 2008 15.94
5 Variation in FTO contributes to childhood obesity and severe adult obesity. Nat Genet 2007 13.62
6 Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge. Nat Genet 2010 6.66
7 A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk. Nat Genet 2008 5.49
8 Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia. Nat Genet 2009 5.43
9 A polymorphism within the G6PC2 gene is associated with fasting plasma glucose levels. Science 2008 4.38
10 Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human. Nature 2012 3.41
11 Type 2 diabetes whole-genome association study in four populations: the DiaGen consortium. Am J Hum Genet 2007 3.31
12 Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nat Genet 2013 3.25
13 Genome-wide association scans identified CTNNBL1 as a novel gene for obesity. Hum Mol Genet 2008 3.24
14 Common nonsynonymous variants in PCSK1 confer risk of obesity. Nat Genet 2008 3.24
15 Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet 2012 3.21
16 Two new Loci for body-weight regulation identified in a joint analysis of genome-wide association studies for early-onset extreme obesity in French and german study groups. PLoS Genet 2010 3.21
17 TCF7L2 is reproducibly associated with type 2 diabetes in various ethnic groups: a global meta-analysis. J Mol Med (Berl) 2007 3.17
18 Transcription factor TCF7L2 genetic study in the French population: expression in human beta-cells and adipose tissue and strong association with type 2 diabetes. Diabetes 2006 2.85
19 Impact of common type 2 diabetes risk polymorphisms in the DESIR prospective study. Diabetes 2007 2.69
20 A genome-wide association meta-analysis identifies new childhood obesity loci. Nat Genet 2012 2.60
21 Non-synonymous polymorphisms in melanocortin-4 receptor protect against obesity: the two facets of a Janus obesity gene. Hum Mol Genet 2007 2.50
22 Loss-of-function mutation in the dioxygenase-encoding FTO gene causes severe growth retardation and multiple malformations. Am J Hum Genet 2009 2.09
23 Comment on "A common genetic variant is associated with adult and childhood obesity". Science 2007 2.04
24 Post genome-wide association studies of novel genes associated with type 2 diabetes show gene-gene interaction and high predictive value. PLoS One 2008 1.94
25 A genome-wide association search for type 2 diabetes genes in African Americans. PLoS One 2012 1.72
26 The genetic susceptibility to type 2 diabetes may be modulated by obesity status: implications for association studies. BMC Med Genet 2008 1.68
27 ACDC/adiponectin polymorphisms are associated with severe childhood and adult obesity. Diabetes 2006 1.62
28 Combined effects of MC4R and FTO common genetic variants on obesity in European general populations. J Mol Med (Berl) 2009 1.62
29 A POMC variant implicates beta-melanocyte-stimulating hormone in the control of human energy balance. Cell Metab 2006 1.59
30 Effects of TCF7L2 polymorphisms on obesity in European populations. Obesity (Silver Spring) 2008 1.49
31 TCF7L2 variation predicts hyperglycemia incidence in a French general population: the data from an epidemiological study on the Insulin Resistance Syndrome (DESIR) study. Diabetes 2006 1.45
32 Obesity genes and risk of major depressive disorder in a multiethnic population: a cross-sectional study. J Clin Psychiatry 2015 1.41
33 Estimation of newborn risk for child or adolescent obesity: lessons from longitudinal birth cohorts. PLoS One 2012 1.35
34 Prevalence of melanocortin-4 receptor deficiency in Europeans and their age-dependent penetrance in multigenerational pedigrees. Diabetes 2008 1.35
35 Genetic variant in HK1 is associated with a proanemic state and A1C but not other glycemic control-related traits. Diabetes 2009 1.29
36 Childhood obesity is associated with shorter leukocyte telomere length. J Clin Endocrinol Metab 2011 1.27
37 Implication of the Pro12Ala polymorphism of the PPAR-gamma 2 gene in type 2 diabetes and obesity in the French population. BMC Med Genet 2005 1.26
38 Genetics of Obesity: What have we Learned? Curr Genomics 2011 1.19
39 Meta-analysis of the INSIG2 association with obesity including 74,345 individuals: does heterogeneity of estimates relate to study design? PLoS Genet 2009 1.18
40 Heterozygous mutations causing partial prohormone convertase 1 deficiency contribute to human obesity. Diabetes 2011 1.12
41 Bardet-Biedl syndrome gene variants are associated with both childhood and adult common obesity in French Caucasians. Diabetes 2006 1.11
42 Genome-wide linkage analysis for severe obesity in french caucasians finds significant susceptibility locus on chromosome 19q. Diabetes 2004 1.10
43 The T-381C SNP in BNP gene may be modestly associated with type 2 diabetes: an updated meta-analysis in 49 279 subjects. Hum Mol Genet 2009 1.09
44 Molecular basis of obesity: current status and future prospects. Curr Genomics 2011 1.07
45 SREBF-1 gene polymorphisms are associated with obesity and type 2 diabetes in French obese and diabetic cohorts. Diabetes 2004 1.05
46 Common variation in SIM1 is reproducibly associated with BMI in Pima Indians. Diabetes 2009 1.04
47 The imprinted gene neuronatin is regulated by metabolic status and associated with obesity. Obesity (Silver Spring) 2009 1.02
48 Analysis of novel risk loci for type 2 diabetes in a general French population: the D.E.S.I.R. study. J Mol Med (Berl) 2008 1.01
49 A rare variant in the visfatin gene (NAMPT/PBEF1) is associated with protection from obesity. Obesity (Silver Spring) 2009 1.01
50 Endocannabinoid receptor 1 gene variations increase risk for obesity and modulate body mass index in European populations. Hum Mol Genet 2008 1.00
51 Study of TNFalpha -308G/A and IL6 -174G/C polymorphisms in type 2 diabetes and obesity risk in the Tunisian population. Clin Biochem 2010 1.00
52 Common variants in FTO, MC4R, TMEM18, PRL, AIF1, and PCSK1 show evidence of association with adult obesity in the Greek population. Obesity (Silver Spring) 2011 0.99
53 Polymorphisms in the amino acid transporter solute carrier family 6 (neurotransmitter transporter) member 14 gene contribute to polygenic obesity in French Caucasians. Diabetes 2004 0.97
54 Adiponectin, type 2 diabetes and the metabolic syndrome: lessons from human genetic studies. Expert Rev Mol Med 2006 0.97
55 Analysis of the contribution of FTO, NPC1, ENPP1, NEGR1, GNPDA2 and MC4R genes to obesity in Mexican children. BMC Med Genet 2013 0.96
56 Loss-of-function mutations in SIM1 contribute to obesity and Prader-Willi-like features. J Clin Invest 2013 0.96
57 Association studies on ghrelin and ghrelin receptor gene polymorphisms with obesity. Obesity (Silver Spring) 2009 0.94
58 Modelling of OGTT curve identifies 1 h plasma glucose level as a strong predictor of incident type 2 diabetes: results from two prospective cohorts. Diabetologia 2014 0.93
59 Genetic and functional assessment of the role of the rs13431652-A and rs573225-A alleles in the G6PC2 promoter that are strongly associated with elevated fasting glucose levels. Diabetes 2010 0.92
60 Causal relationship between adiponectin and metabolic traits: a Mendelian randomization study in a multiethnic population. PLoS One 2013 0.92
61 Preferential reciprocal transfer of paternal/maternal DLK1 alleles to obese children: first evidence of polar overdominance in humans. Eur J Hum Genet 2008 0.91
62 Evaluation of A2BP1 as an obesity gene. Diabetes 2010 0.91
63 A genome-wide association study identifies rs2000999 as a strong genetic determinant of circulating haptoglobin levels. PLoS One 2012 0.89
64 The INS VNTR locus does not associate with smallness for gestational age (SGA) but interacts with SGA to increase insulin resistance in young adults. J Clin Endocrinol Metab 2006 0.89
65 Rare genomic structural variants in complex disease: lessons from the replication of associations with obesity. PLoS One 2013 0.88
66 MTNR1B G24E variant associates With BMI and fasting plasma glucose in the general population in studies of 22,142 Europeans. Diabetes 2010 0.86
67 Analysis of the SIM1 contribution to polygenic obesity in the French population. Obesity (Silver Spring) 2010 0.84
68 Early detrimental metabolic outcomes of rs17300539-A allele of ADIPOQ gene despite higher adiponectinemia. Obesity (Silver Spring) 2009 0.84
69 Does genetic heterogeneity account for the divergent risk of type 2 diabetes in South Asian and white European populations? Diabetologia 2014 0.84
70 Genetic study of the melanin-concentrating hormone receptor 2 in childhood and adulthood severe obesity. J Clin Endocrinol Metab 2007 0.83
71 Novel association approach for variable number tandem repeats (VNTRs) identifies DOCK5 as a susceptibility gene for severe obesity. Hum Mol Genet 2012 0.83
72 TCF7L2 rs7903146 variant does not associate with smallness for gestational age in the French population. BMC Med Genet 2007 0.83
73 Serum adiponectin is related to plasma high-density lipoprotein cholesterol but not to plasma insulin-concentration in healthy children: the FLVS II study. Metabolism 2006 0.83
74 Lack of association of CD36 SNPs with early onset obesity: a meta-analysis in 9,973 European subjects. Obesity (Silver Spring) 2010 0.83
75 The Q121 variant of ENPP1 may protect from childhood overweight/obesity in the Italian population. Obesity (Silver Spring) 2008 0.82
76 Evaluating the association of FAAH common gene variation with childhood, adult severe obesity and type 2 diabetes in the French population. Obes Facts 2008 0.82
77 Association of melanin-concentrating hormone receptor 1 5' polymorphism with early-onset extreme obesity. Diabetes 2005 0.82
78 Genomic insights into early-onset obesity. Genome Med 2010 0.81
79 Association analysis indicates that a variant GATA-binding site in the PIK3CB promoter is a Cis-acting expression quantitative trait locus for this gene and attenuates insulin resistance in obese children. Diabetes 2007 0.79
80 Genetic information and the prediction of incident type 2 diabetes in a high-risk multiethnic population: the EpiDREAM genetic study. Diabetes Care 2013 0.79
81 Common variants near BDNF and SH2B1 show nominal evidence of association with snacking behavior in European populations. J Mol Med (Berl) 2013 0.79
82 Secretory granule neuroendocrine protein 1 (SGNE1) genetic variation and glucose intolerance in severe childhood and adult obesity. BMC Med Genet 2007 0.78
83 Loss-of-function mutations in MC4R are very rare in the Greek severely obese adult population. Obesity (Silver Spring) 2012 0.77
84 Identification of two novel loss-of-function SIM1 mutations in two overweight children with developmental delay. Obesity (Silver Spring) 2014 0.76
85 INS VNTR is not associated with childhood obesity in 1,023 families: a family-based study. Obesity (Silver Spring) 2008 0.76
86 Concordance of two multiple analytical approaches demonstrate that interaction between BMI and ADIPOQ haplotypes is a determinant of LDL cholesterol in a general French population. J Hum Genet 2010 0.76
87 No contribution of angiotensin-converting enzyme (ACE) gene variants to severe obesity: a model for comprehensive case/control and quantitative cladistic analysis of ACE in human diseases. Eur J Hum Genet 2006 0.75
88 Physical Activity and Global Self-worth in a Longitudinal Study of Children. Med Sci Sports Exerc 2017 0.75
89 An evolutionary genetic perspective of eating disorders. Neuroendocrinology 2017 0.75