Published in Bioinformatics on January 19, 2007
Network-based global inference of human disease genes. Mol Syst Biol (2008) 5.01
Genome-wide prioritization of disease genes and identification of disease-disease associations from an integrated human functional linkage network. Genome Biol (2009) 2.43
Strategies and issues in the detection of pathway enrichment in genome-wide association studies. Hum Genet (2009) 2.31
ENDEAVOUR update: a web resource for gene prioritization in multiple species. Nucleic Acids Res (2008) 2.31
Comprehensive association study of type 2 diabetes and related quantitative traits with 222 candidate genes. Diabetes (2008) 2.01
The power of protein interaction networks for associating genes with diseases. Bioinformatics (2010) 1.96
Systematic biological prioritization after a genome-wide association study: an application to nicotine dependence. Bioinformatics (2008) 1.85
FitSNPs: highly differentially expressed genes are more likely to have variants associated with disease. Genome Biol (2008) 1.58
Bioinformatics for personal genome interpretation. Brief Bioinform (2012) 1.51
Enhancing the prioritization of disease-causing genes through tissue specific protein interaction networks. PLoS Comput Biol (2012) 1.51
Mining phenotypes for gene function prediction. BMC Bioinformatics (2008) 1.41
Prioritization of disease microRNAs through a human phenome-microRNAome network. BMC Syst Biol (2010) 1.37
Uncover disease genes by maximizing information flow in the phenome-interactome network. Bioinformatics (2011) 1.32
Advances in translational bioinformatics: computational approaches for the hunting of disease genes. Brief Bioinform (2009) 1.27
Approaches for recognizing disease genes based on network. Biomed Res Int (2014) 1.06
Chapter 15: disease gene prioritization. PLoS Comput Biol (2013) 1.05
Constructing a gene semantic similarity network for the inference of disease genes. BMC Syst Biol (2011) 1.05
Inferring novel gene-disease associations using Medical Subject Heading Over-representation Profiles. Genome Med (2012) 1.01
Integrating multiple protein-protein interaction networks to prioritize disease genes: a Bayesian regression approach. BMC Bioinformatics (2011) 0.96
k-Neighborhood decentralization: a comprehensive solution to index the UMLS for large scale knowledge discovery. J Biomed Inform (2011) 0.95
Revealing and avoiding bias in semantic similarity scores for protein pairs. BMC Bioinformatics (2010) 0.95
Studies of the association of Arg72Pro of tumor suppressor protein p53 with type 2 diabetes in a combined analysis of 55,521 Europeans. PLoS One (2011) 0.92
Gene prioritization and clustering by multi-view text mining. BMC Bioinformatics (2010) 0.91
Integrating human omics data to prioritize candidate genes. BMC Med Genomics (2013) 0.88
Retracted Candidate gene prioritization. Mol Genet Genomics (2012) 0.88
Transactional database transformation and its application in prioritizing human disease genes. IEEE/ACM Trans Comput Biol Bioinform (2011) 0.87
Metab2MeSH: annotating compounds with medical subject headings. Bioinformatics (2012) 0.85
Text mining in cancer gene and pathway prioritization. Cancer Inform (2014) 0.85
DomainRBF: a Bayesian regression approach to the prioritization of candidate domains for complex diseases. BMC Syst Biol (2011) 0.82
GPSy: a cross-species gene prioritization system for conserved biological processes--application in male gamete development. Nucleic Acids Res (2012) 0.82
BICEPP: an example-based statistical text mining method for predicting the binary characteristics of drugs. BMC Bioinformatics (2011) 0.82
ProphNet: a generic prioritization method through propagation of information. BMC Bioinformatics (2014) 0.82
A computational method based on the integration of heterogeneous networks for predicting disease-gene associations. PLoS One (2011) 0.80
Identification of Parkinson's disease candidate genes using CAESAR and screening of MAPT and SNCAIP in South African Parkinson's disease patients. J Neural Transm (Vienna) (2011) 0.79
In silico prioritisation of candidate genes for prokaryotic gene function discovery: an application of phylogenetic profiles. BMC Bioinformatics (2009) 0.77
Information-based methods for predicting gene function from systematic gene knock-downs. BMC Bioinformatics (2008) 0.77
A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants. Science (2007) 43.16
Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Nat Genet (2008) 35.06
Biological, clinical and population relevance of 95 loci for blood lipids. Nature (2010) 28.21
Newly identified loci that influence lipid concentrations and risk of coronary artery disease. Nat Genet (2008) 25.83
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet (2010) 23.08
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet (2008) 22.35
Common variants at 30 loci contribute to polygenic dyslipidemia. Nat Genet (2008) 20.66
Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature (2010) 20.01
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet (2010) 17.89
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat Genet (2010) 16.96
Identification of ten loci associated with height highlights new biological pathways in human growth. Nat Genet (2008) 16.25
Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet (2008) 15.94
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25
Genome-wide association study identifies eight loci associated with blood pressure. Nat Genet (2009) 12.44
Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study. Lancet (2012) 12.10
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat Genet (2012) 11.09
Variants in MTNR1B influence fasting glucose levels. Nat Genet (2008) 10.85
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet (2010) 7.94
Common variants in the GDF5-UQCC region are associated with variation in human height. Nat Genet (2008) 7.31
A map of open chromatin in human pancreatic islets. Nat Genet (2010) 6.75
Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge. Nat Genet (2010) 6.66
Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution. PLoS Genet (2009) 5.81
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Nat Genet (2012) 4.73
Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians. Nat Genet (2011) 4.50
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. Nat Genet (2012) 4.37
The iPlant Collaborative: Cyberinfrastructure for Plant Biology. Front Plant Sci (2011) 4.16
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nat Genet (2014) 4.13
Genetic variants influencing circulating lipid levels and risk of coronary artery disease. Arterioscler Thromb Vasc Biol (2010) 4.08
Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways. Diabetes (2010) 4.07
Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children. PLoS Med (2011) 3.94
Data archiving is a good investment. Nature (2011) 3.53
Variations in the G6PC2/ABCB11 genomic region are associated with fasting glucose levels. J Clin Invest (2008) 3.51
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nat Genet (2013) 3.25
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet (2012) 3.21
Common variants associated with plasma triglycerides and risk for coronary artery disease. Nat Genet (2013) 2.92
Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits. PLoS Genet (2013) 2.83
INK4/ARF transcript expression is associated with chromosome 9p21 variants linked to atherosclerosis. PLoS One (2009) 2.77
FTO genotype is associated with phenotypic variability of body mass index. Nature (2012) 2.77
Fast identification and statistical evaluation of segmental homologies in comparative maps. Bioinformatics (2003) 2.68
Association of transcription factor 7-like 2 (TCF7L2) variants with type 2 diabetes in a Finnish sample. Diabetes (2006) 2.58
Exome array analysis identifies new loci and low-frequency variants influencing insulin processing and secretion. Nat Genet (2012) 2.55
A large set of Finnish affected sibling pair families with type 2 diabetes suggests susceptibility loci on chromosomes 6, 11, and 14. Diabetes (2004) 2.46
Detailed physiologic characterization reveals diverse mechanisms for novel genetic Loci regulating glucose and insulin metabolism in humans. Diabetes (2010) 2.44
Genetic variation near the hepatocyte nuclear factor-4 alpha gene predicts susceptibility to type 2 diabetes. Diabetes (2004) 2.43
Contrasting modes of diversification in the Aux/IAA and ARF gene families. Plant Physiol (2004) 2.41
Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases. PLoS Genet (2012) 2.34
Insights into evolution of multicellular fungi from the assembled chromosomes of the mushroom Coprinopsis cinerea (Coprinus cinereus). Proc Natl Acad Sci U S A (2010) 2.30
Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight. Nat Genet (2010) 2.30
Phenex: ontological annotation of phenotypic diversity. PLoS One (2010) 2.13
The teleost anatomy ontology: anatomical representation for the genomics age. Syst Biol (2010) 2.07
Common variants in maturity-onset diabetes of the young genes contribute to risk of type 2 diabetes in Finns. Diabetes (2006) 2.03
Comprehensive association study of type 2 diabetes and related quantitative traits with 222 candidate genes. Diabetes (2008) 2.01
Patterns of nucleotide substitution among simultaneously duplicated gene pairs in Arabidopsis thaliana. Mol Biol Evol (2002) 1.97
Evolutionary characters, phenotypes and ontologies: curating data from the systematic biology literature. PLoS One (2010) 1.93
New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism. Nat Genet (2012) 1.90
Divergence in expression between duplicated genes in Arabidopsis. Mol Biol Evol (2007) 1.83
Data reuse and the open data citation advantage. PeerJ (2013) 1.79
Screening of 134 single nucleotide polymorphisms (SNPs) previously associated with type 2 diabetes replicates association with 12 SNPs in nine genes. Diabetes (2007) 1.74
Tag SNP selection for Finnish individuals based on the CEPH Utah HapMap database. Genet Epidemiol (2006) 1.74
A genome-wide association search for type 2 diabetes genes in African Americans. PLoS One (2012) 1.72
Evaluation of the metabochip genotyping array in African Americans and implications for fine mapping of GWAS-identified loci: the PAGE study. PLoS One (2012) 1.65
Trans-ethnic fine-mapping of lipid loci identifies population-specific signals and allelic heterogeneity that increases the trait variance explained. PLoS Genet (2013) 1.57
Gene × physical activity interactions in obesity: combined analysis of 111,421 individuals of European ancestry. PLoS Genet (2013) 1.51
Using ESTs for phylogenomics: can one accurately infer a phylogenetic tree from a gappy alignment? BMC Evol Biol (2008) 1.45
Identification and characterization of aluminum tolerance loci in Arabidopsis (Landsberg erecta x Columbia) by quantitative trait locus mapping. A physiologically simple but genetically complex trait. Plant Physiol (2003) 1.39
500,000 fish phenotypes: The new informatics landscape for evolutionary and developmental biology of the vertebrate skeleton. J Appl Ichthyol (2012) 1.38
Genome-wide association study for adiponectin levels in Filipino women identifies CDH13 and a novel uncommon haplotype at KNG1-ADIPOQ. Hum Mol Genet (2010) 1.38
Genome-scale phylogenetics: inferring the plant tree of life from 18,896 gene trees. Syst Biol (2010) 1.36
Phytome: a platform for plant comparative genomics. Nucleic Acids Res (2006) 1.35
Genome-wide association study of homocysteine levels in Filipinos provides evidence for CPS1 in women and a stronger MTHFR effect in young adults. Hum Mol Genet (2010) 1.35
Association of FTO with obesity-related traits in the Cebu Longitudinal Health and Nutrition Survey (CLHNS) Cohort. Diabetes (2008) 1.26
Improving quantitative trait loci mapping resolution in experimental crosses by the use of genotypically selected samples. Genetics (2005) 1.25
Mendelian randomization studies do not support a causal role for reduced circulating adiponectin levels in insulin resistance and type 2 diabetes. Diabetes (2013) 1.25
Meta-analysis of the INSIG2 association with obesity including 74,345 individuals: does heterogeneity of estimates relate to study design? PLoS Genet (2009) 1.18
Comparison of ENCODE region SNPs between Cebu Filipino and Asian HapMap samples. J Hum Genet (2007) 1.08
Finding genes and variants for lipid levels after genome-wide association analysis. Curr Opin Lipidol (2012) 1.08
Genome-wide association study of anthropometric traits and evidence of interactions with age and study year in Filipino women. Obesity (Silver Spring) (2010) 1.05
Allelic expression imbalance at high-density lipoprotein cholesterol locus MMAB-MVK. Hum Mol Genet (2010) 1.05
Population-specific coding variant underlies genome-wide association with adiponectin level. Hum Mol Genet (2011) 1.04
The vertebrate taxonomy ontology: a framework for reasoning across model organism and species phenotypes. J Biomed Semantics (2013) 1.02
Genome-wide association with C-reactive protein levels in CLHNS: evidence for the CRP and HNF1A loci and their interaction with exposure to a pathogenic environment. Inflammation (2012) 0.97
Allele-specific transcriptional activity at type 2 diabetes-associated single nucleotide polymorphisms in regions of pancreatic islet open chromatin at the JAZF1 locus. Diabetes (2013) 0.94
Variation in three single nucleotide polymorphisms in the calpain-10 gene not associated with type 2 diabetes in a large Finnish cohort. Diabetes (2002) 0.92
Association of ketone body levels with hyperglycemia and type 2 diabetes in 9,398 Finnish men. Diabetes (2013) 0.92
A meta-analysis of genome-wide association studies for adiponectin levels in East Asians identifies a novel locus near WDR11-FGFR2. Hum Mol Genet (2013) 0.91
Tracking the evolution of alternatively spliced exons within the Dscam family. BMC Evol Biol (2006) 0.90
A comprehensive SNP and indel imputability database. Bioinformatics (2013) 0.90
Spontaneous Irs1 passenger mutation linked to a gene-targeted SerpinB2 allele. Proc Natl Acad Sci U S A (2010) 0.87
Genetic association with lipids in Filipinos: waist circumference modifies an APOA5 effect on triglyceride levels. J Lipid Res (2013) 0.87
Fine-mapping and initial characterization of QT interval loci in African Americans. PLoS Genet (2012) 0.86
Fine mapping a QTL for carbon isotope composition in tomato. Theor Appl Genet (2008) 0.86
The standing pool of genomic structural variation in a natural population of Mimulus guttatus. Genome Biol Evol (2014) 0.84
Obesity genes: so close and yet so far... J Biol (2008) 0.84
Nonsynonymous variants and fatty liver disease. Nat Genet (2008) 0.83
Single-nucleotide polymorphisms at five loci are associated with C-reactive protein levels in a cohort of Filipino young adults. J Hum Genet (2011) 0.83
Systematic identification of balanced transposition polymorphisms in Saccharomyces cerevisiae. PLoS Genet (2009) 0.81
Associations of genetic variants in/near body mass index-associated genes with type 2 diabetes: a systematic meta-analysis. Clin Endocrinol (Oxf) (2014) 0.81
Compensatory evolution in RNA secondary structures increases substitution rate variation among sites. Mol Biol Evol (2008) 0.81
A hierarchical model for incomplete alignments in phylogenetic inference. Bioinformatics (2009) 0.76
Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. PLoS Genet (2016) 0.75