Published in J Immunol on March 01, 2007
Essential and unique roles of PIP5K-gamma and -alpha in Fcgamma receptor-mediated phagocytosis. J Cell Biol (2009) 1.23
Targeting of pseudorabies virus structural proteins to axons requires association of the viral Us9 protein with lipid rafts. PLoS Pathog (2008) 1.12
Pathogen destruction versus intracellular survival: the role of lipids as phagosomal fate determinants. J Clin Invest (2008) 1.10
Reovirus FAST protein transmembrane domains function in a modular, primary sequence-independent manner to mediate cell-cell membrane fusion. J Virol (2009) 0.93
Divergent intracellular sorting of Fc{gamma}RIIA and Fc{gamma}RIIB2. J Biol Chem (2010) 0.93
Fc gammaRIIIb triggers raft-dependent calcium influx in IgG-mediated responses in human neutrophils. J Biol Chem (2010) 0.87
Differential requirement of lipid rafts for FcγRIIA mediated effector activities. Cell Immunol (2010) 0.79
Differential Use of Human Neutrophil Fcγ Receptors for Inducing Neutrophil Extracellular Trap Formation. J Immunol Res (2016) 0.77
Activatory and inhibitory Fcγ receptors augment rituximab-mediated internalization of CD20 independent of signaling via the cytoplasmic domain. J Biol Chem (2015) 0.76
Characterization of NF-κB Reporter U937 Cells and Their Application for the Detection of Inflammatory Immune-Complexes. PLoS One (2016) 0.75
DENV up-regulates the HMG-CoA reductase activity through the impairment of AMPK phosphorylation: A potential antiviral target. PLoS Pathog (2017) 0.75
Fcγ-receptor IIa-mediated Src Signaling Pathway is Essential for the Antibody-Dependent Enhancement of Ebola Virus Infection. PLoS Pathog (2016) 0.75
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Germline transmission and tissue-specific expression of transgenes delivered by lentiviral vectors. Science (2002) 17.71
The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor. Nature (2005) 7.18
Deletion of the developmentally essential gene ATR in adult mice leads to age-related phenotypes and stem cell loss. Cell Stem Cell (2007) 6.02
A mycobacterial virulence gene cluster extending RD1 is required for cytolysis, bacterial spreading and ESAT-6 secretion. Mol Microbiol (2004) 3.53
Acute postnatal ablation of Hif-2alpha results in anemia. Proc Natl Acad Sci U S A (2007) 3.51
Disruption of the mouse mTOR gene leads to early postimplantation lethality and prohibits embryonic stem cell development. Mol Cell Biol (2004) 3.20
C-terminal signal sequence promotes virulence factor secretion in Mycobacterium tuberculosis. Science (2006) 2.72
Dysfunctional telomeres activate an ATM-ATR-dependent DNA damage response to suppress tumorigenesis. EMBO J (2007) 2.61
Activation of Notch1 signaling is required for beta-catenin-mediated human primary melanoma progression. J Clin Invest (2005) 2.38
Mycobacterium marinum escapes from phagosomes and is propelled by actin-based motility. J Exp Med (2003) 2.30
ESX-1-dependent cytolysis in lysosome secretion and inflammasome activation during mycobacterial infection. Cell Microbiol (2008) 2.01
A mycobacterium ESX-1-secreted virulence factor with unique requirements for export. PLoS Pathog (2007) 2.00
Systematic genetic nomenclature for type VII secretion systems. PLoS Pathog (2009) 1.96
Requirement for kasB in Mycobacterium mycolic acid biosynthesis, cell wall impermeability and intracellular survival: implications for therapy. Mol Microbiol (2003) 1.91
PLIC proteins or ubiquilins regulate autophagy-dependent cell survival during nutrient starvation. EMBO Rep (2009) 1.89
Combining ATR suppression with oncogenic Ras synergistically increases genomic instability, causing synthetic lethality or tumorigenesis in a dosage-dependent manner. Cancer Res (2010) 1.82
The tumor suppressor menin regulates hematopoiesis and myeloid transformation by influencing Hox gene expression. Proc Natl Acad Sci U S A (2006) 1.67
Macrophage complement receptors and pathogen clearance. Cell Microbiol (2007) 1.65
HIF2alpha inhibition promotes p53 pathway activity, tumor cell death, and radiation responses. Proc Natl Acad Sci U S A (2009) 1.59
Transposon mutagenesis of Mycobacterium marinum identifies a locus linking pigmentation and intracellular survival. Infect Immun (2003) 1.59
Atg5-independent sequestration of ubiquitinated mycobacteria. PLoS Pathog (2009) 1.55
ATR and H2AX cooperate in maintaining genome stability under replication stress. J Biol Chem (2008) 1.55
RPA accumulation during class switch recombination represents 5'-3' DNA-end resection during the S-G2/M phase of the cell cycle. Cell Rep (2013) 1.53
Signal transduction during Fc receptor-mediated phagocytosis. J Leukoc Biol (2002) 1.52
Tissue regenerative delays and synthetic lethality in adult mice after combined deletion of Atr and Trp53. Nat Genet (2009) 1.51
Interactions between CD47 and thrombospondin reduce inflammation. J Immunol (2007) 1.46
Oncogenic stress sensitizes murine cancers to hypomorphic suppression of ATR. J Clin Invest (2011) 1.46
Mycobacterium marinum: the generalization and specialization of a pathogenic mycobacterium. Microbes Infect (2004) 1.43
Genotoxic stress-induced cyclin D1 phosphorylation and proteolysis are required for genomic stability. Mol Cell Biol (2008) 1.37
Polar localization of virulence-related Esx-1 secretion in mycobacteria. PLoS Pathog (2009) 1.32
A mycobacterial operon essential for virulence in vivo and invasion and intracellular persistence in macrophages. Infect Immun (2006) 1.31
Host-detrimental role of Esx-1-mediated inflammasome activation in mycobacterial infection. PLoS Pathog (2010) 1.31
Phosphorylation of MLL by ATR is required for execution of mammalian S-phase checkpoint. Nature (2010) 1.29
Role of the WASP family proteins for Mycobacterium marinum actin tail formation. Proc Natl Acad Sci U S A (2005) 1.25
Role for plastin in host defense distinguishes integrin signaling from cell adhesion and spreading. Immunity (2003) 1.21
Evidence that the red cell skeleton protein 4.2 interacts with the Rh membrane complex member CD47. Blood (2002) 1.20
Aberrant Epstein-Barr viral infection in systemic lupus erythematosus. Autoimmun Rev (2009) 1.20
CD47 deficiency protects mice from lipopolysaccharide-induced acute lung injury and Escherichia coli pneumonia. J Immunol (2008) 1.19
Mechanisms of CD47-induced caspase-independent cell death in normal and leukemic cells: link between phosphatidylserine exposure and cytoskeleton organization. Blood (2002) 1.19
A delicate dance: host response to mycobacteria. Curr Opin Immunol (2011) 1.18
A co-operative interaction between Neisseria gonorrhoeae and complement receptor 3 mediates infection of primary cervical epithelial cells. Cell Microbiol (2002) 1.18
RNF4 and PLK1 are required for replication fork collapse in ATR-deficient cells. Genes Dev (2013) 1.17
Tim-Tipin dysfunction creates an indispensible reliance on the ATR-Chk1 pathway for continued DNA synthesis. J Cell Biol (2009) 1.15
Replicative stress, stem cells and aging. Mech Ageing Dev (2008) 1.14
Actin-based motility of intracellular bacteria, and polarized surface distribution of the bacterial effector molecules. J Cell Physiol (2006) 1.14
Cytosol as battleground: ubiquitin as a weapon for both host and pathogen. Trends Cell Biol (2010) 1.13
The ubiquitin-related protein PLIC-1 regulates heterotrimeric G protein function through association with Gbetagamma. J Cell Biol (2003) 1.09
Role for lysosomal enzyme beta-hexosaminidase in the control of mycobacteria infection. Proc Natl Acad Sci U S A (2008) 1.08
Dual regulation of SIRPalpha phosphorylation by integrins and CD47. J Biol Chem (2007) 1.08
Conditional deletion of SLP-76 in mature T cells abrogates peripheral immune responses. Eur J Immunol (2011) 1.07
Global gene expression of methicillin-resistant Staphylococcus aureus USA300 during human and mouse infection. J Infect Dis (2013) 1.07
ANIT toxicity toward mouse hepatocytes in vivo is mediated primarily by neutrophils via CD18. Am J Physiol Gastrointest Liver Physiol (2006) 1.03
Generation of mice with a conditional allele of the p120 Ras GTPase-activating protein. Genesis (2007) 1.03
R-Ras promotes tumor growth of cervical epithelial cells. Cancer (2003) 1.01
Actin-bundling protein L-plastin regulates T cell activation. J Immunol (2010) 1.01
ATR acts stage specifically to regulate multiple aspects of mammalian meiotic silencing. Genes Dev (2013) 1.01
ATR maintains select progenitors during nervous system development. EMBO J (2012) 1.00
Timeless Maintains Genomic Stability and Suppresses Sister Chromatid Exchange during Unperturbed DNA Replication. J Biol Chem (2008) 1.00
The ubiquitin-like protein PLIC-2 is a negative regulator of G protein-coupled receptor endocytosis. Mol Biol Cell (2008) 0.99
Coordination of chondrocyte differentiation and joint formation by alpha5beta1 integrin in the developing appendicular skeleton. Development (2004) 0.98
Novel staphylococcal glycosyltransferases SdgA and SdgB mediate immunogenicity and protection of virulence-associated cell wall proteins. PLoS Pathog (2013) 0.98
The actin-bundling protein L-plastin dissociates CCR7 proximal signaling from CCR7-induced motility. J Immunol (2010) 0.97
Removing all obstacles: a critical role for p53 in promoting tissue renewal. Cell Cycle (2010) 0.94
Protein kinase C delta stimulates apoptosis by initiating G1 phase cell cycle progression and S phase arrest. J Biol Chem (2005) 0.93
FcgammaRIIA and FcgammaRIIIB mediate nuclear factor activation through separate signaling pathways in human neutrophils. J Immunol (2009) 0.93
Ubiquilins in the crosstalk among proteolytic pathways. Biol Chem (2012) 0.93
beta1 and beta2 integrins activate different signalling pathways in monocytes. Biochem J (2002) 0.92
Macrophage--Mycobacterium tuberculosis interactions: role of complement receptor 3. Microb Pathog (2003) 0.92
Cross-talk between Fc receptors and integrins. Immunol Lett (2003) 0.91
Novel CD47-dependent intercellular adhesion modulates cell migration. J Cell Physiol (2005) 0.90
R-Ras promotes metastasis of cervical cancer epithelial cells. Cancer Immunol Immunother (2006) 0.89
In vivo bioimaging tracks conditionally replicative adenoviral replication and provides an early indication of viral antitumor efficacy. Cancer Sci (2009) 0.89
Selective deletion of a cell cycle checkpoint kinase (ATR) reduces neurogenesis and alters responses in rodent models of behavioral affect. Neuropsychopharmacology (2011) 0.89
Protein tyrosine phosphatase SHP-1 positively regulates TLR-induced IL-12p40 production in macrophages through inhibition of phosphatidylinositol 3-kinase. J Leukoc Biol (2010) 0.88
Coxiella burnetii avoids macrophage phagocytosis by interfering with spatial distribution of complement receptor 3. J Immunol (2003) 0.87
Involvement of a CD47-dependent pathway in platelet adhesion on inflamed vascular endothelium under flow. Blood (2003) 0.86
EccA1, a component of the Mycobacterium marinum ESX-1 protein virulence factor secretion pathway, regulates mycolic acid lipid synthesis. Chem Biol (2012) 0.86
Ubiquilins accelerate autophagosome maturation and promote cell survival during nutrient starvation. Autophagy (2009) 0.85
Fcgamma receptors exhibit different phagocytosis potential in human neutrophils. Cell Immunol (2010) 0.85
Identifying potential therapeutic targets of methicillin-resistant Staphylococcus aureus through in vivo proteomic analysis. J Infect Dis (2013) 0.85
Ubiquilin4 is an adaptor protein that recruits Ubiquilin1 to the autophagy machinery. EMBO Rep (2013) 0.84
Nuclear factor activation by FcgammaR in human peripheral blood neutrophils detected by a novel flow cytometry-based method. J Immunol Methods (2007) 0.84
Immune responses of mussel hemocyte subpopulations are differentially regulated by enzymes of the PI 3-K, PKC, and ERK kinase families. Dev Comp Immunol (2007) 0.84
Phosphatidylinositol 3-kinase and extracellular signal-regulated kinase are recruited for Fc receptor-mediated phagocytosis during monocyte-to-macrophage differentiation. J Leukoc Biol (2002) 0.83
Degraded carrageenan causing colitis in rats induces TNF secretion and ICAM-1 upregulation in monocytes through NF-kappaB activation. PLoS One (2010) 0.82
Fc gammaRIIIB stimulation promotes beta1 integrin activation in human neutrophils. J Leukoc Biol (2005) 0.82
Expression and activation of signal regulatory protein alpha on astrocytomas. Cancer Res (2004) 0.82
Chk'ing p53-deficient breast cancers. J Clin Invest (2012) 0.81
Regression of human papillomavirus intraepithelial lesions is induced by MVA E2 therapeutic vaccine. Hum Gene Ther (2014) 0.81
Chemotaxis of non-compressed blood polymorphonuclear leukocytes from an adolescent with severe leukocyte adhesion deficiency. Am J Hematol (2003) 0.80
An fMLP receptor is involved in activation of phagocytosis by hemocytes from specific insect species. Dev Comp Immunol (2009) 0.80
Mycobacterium marinum SecA2 promotes stable granulomas and induces tumor necrosis factor alpha in vivo. Infect Immun (2012) 0.80
Entamoeba histolytica: a beta 1 integrin-like fibronectin receptor assembles a signaling complex similar to those of mammalian cells. Exp Parasitol (2003) 0.79
A simple and efficient method to detect nuclear factor activation in human neutrophils by flow cytometry. J Vis Exp (2013) 0.79
Cell biology. The art of making an exit. Science (2009) 0.77
[Fc receptor functions in host and immune regulation]. Rev Invest Clin (2009) 0.76
Impaired FcεRI stability, signaling, and effector functions in murine mast cells lacking glycosylphosphatidylinositol-anchored proteins. Blood (2011) 0.75
Family perspective on a family care program. Rev Lat Am Enfermagem (2008) 0.75
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