Published in Proc Natl Acad Sci U S A on January 15, 1992
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c-Myc target genes involved in cell growth, apoptosis, and metabolism. Mol Cell Biol (1999) 8.17
Multiple DNA and protein sequence alignment based on segment-to-segment comparison. Proc Natl Acad Sci U S A (1996) 6.02
Identification of a new family of tissue-specific basic helix-loop-helix proteins with a two-hybrid system. Mol Cell Biol (1995) 5.71
The Arabidopsis basic/helix-loop-helix transcription factor family. Plant Cell (2003) 5.68
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Binding of myc proteins to canonical and noncanonical DNA sequences. Mol Cell Biol (1993) 4.08
Structure and function of the b/HLH/Z domain of USF. EMBO J (1994) 3.70
A natural classification of the basic helix-loop-helix class of transcription factors. Proc Natl Acad Sci U S A (1997) 3.52
Dual DNA binding specificity of ADD1/SREBP1 controlled by a single amino acid in the basic helix-loop-helix domain. Mol Cell Biol (1995) 3.10
The basic helix-loop-helix protein family: comparative genomics and phylogenetic analysis. Genome Res (2001) 2.47
Single amino acid substitutions alter helix-loop-helix protein specificity for bases flanking the core CANNTG motif. EMBO J (1992) 2.34
Crystal structure of PHO4 bHLH domain-DNA complex: flanking base recognition. EMBO J (1997) 2.01
Chromatin structure modulation in Saccharomyces cerevisiae by centromere and promoter factor 1. Mol Cell Biol (1994) 1.74
A genomewide survey of basic helix-loop-helix factors in Drosophila. Proc Natl Acad Sci U S A (2000) 1.72
Base preferences for DNA binding by the bHLH-Zip protein USF: effects of MgCl2 on specificity and comparison with binding of Myc family members. Nucleic Acids Res (1994) 1.61
Possible cross-regulation of phosphate and sulfate metabolism in Saccharomyces cerevisiae. Genetics (1992) 1.48
Activation domains of L-Myc and c-Myc determine their transforming potencies in rat embryo cells. Mol Cell Biol (1992) 1.39
A point mutation in the MyoD basic domain imparts c-Myc-like properties. Proc Natl Acad Sci U S A (1992) 1.32
Antiproliferative properties of the USF family of helix-loop-helix transcription factors. Proc Natl Acad Sci U S A (1996) 1.30
Oncogenes in tumor metabolism, tumorigenesis, and apoptosis. J Bioenerg Biomembr (1997) 1.28
Mediation of NGF signaling by post-translational inhibition of HES-1, a basic helix-loop-helix repressor of neuronal differentiation. Genes Dev (1997) 1.28
Opposite orientations of DNA bending by c-Myc and Max. Proc Natl Acad Sci U S A (1992) 1.27
Target specificities of Drosophila enhancer of split basic helix-loop-helix proteins. Mol Cell Biol (1999) 1.26
The yeast centromere CDEI/Cpf1 complex: differences between in vitro binding and in vivo function. Nucleic Acids Res (1994) 1.22
Differential binding of c-Myc and Max to nucleosomal DNA. Mol Cell Biol (1994) 1.19
Establishment of distinct MyoD, E2A, and twist DNA binding specificities by different basic region-DNA conformations. Mol Cell Biol (2000) 1.11
Mutational analysis of the Saccharomyces cerevisiae general regulatory factor CP1. Nucleic Acids Res (1993) 1.07
Molecular characterization and mapping of ATOH7, a human atonal homolog with a predicted role in retinal ganglion cell development. Mamm Genome (2002) 1.03
A baculovirus gp64 early promoter is activated by host transcription factor binding to CACGTG and GATA elements. J Virol (1994) 1.03
Molecular and functional interactions of transcription factor USF with the long terminal repeat of human immunodeficiency virus type 1. J Virol (1995) 1.02
Down-regulation of AP-4 inhibits proliferation, induces cell cycle arrest and promotes apoptosis in human gastric cancer cells. PLoS One (2012) 1.00
Transrepression of lck gene expression by human T-cell leukemia virus type 1-encoded p40tax. J Virol (1997) 1.00
Phylogenetic footprinting analysis in the upstream regulatory regions of the Drosophila enhancer of split genes. Genetics (2007) 0.99
Interpretation of X chromosome dose at Sex-lethal requires non-E-box sites for the basic helix-loop-helix proteins SISB and daughterless. Mol Cell Biol (2001) 0.98
Characterization of the human immunoglobulin kappa gene 3' enhancer: functional importance of three motifs that demonstrate B-cell-specific in vivo footprints. Mol Cell Biol (1992) 0.96
Lac repressor with the helix-turn-helix motif of lambda cro binds to lac operator. EMBO J (1992) 0.95
HEN1 encodes a 20-kilodalton phosphoprotein that binds an extended E-box motif as a homodimer. Mol Cell Biol (1994) 0.95
Silencing of the Epstein-Barr virus latent membrane protein 1 gene by the Max-Mad1-mSin3A modulator of chromatin structure. J Virol (1999) 0.95
Analysis of the DNA-binding and dimerization activities of Neurospora crassa transcription factor NUC-1. Mol Cell Biol (1994) 0.92
Rhabdomyosarcomas do not contain mutations in the DNA binding domains of myogenic transcription factors. J Clin Invest (1994) 0.91
Transcriptional specificity of Drosophila dysfusion and the control of tracheal fusion cell gene expression. J Biol Chem (2007) 0.90
Upstream stimulatory factor regulates major histocompatibility complex class I gene expression: the U2DeltaE4 splice variant abrogates E-box activity. Mol Cell Biol (1999) 0.86
Transplantation of a 17-amino acid alpha-helical DNA-binding domain into an antibody molecule confers sequence-dependent DNA recognition. Proc Natl Acad Sci U S A (1995) 0.85
Overproduction of v-Myc in the nucleus and its excess over Max are not required for avian fibroblast transformation. Mol Cell Biol (1993) 0.85
Hairy and Groucho mediate the action of juvenile hormone receptor Methoprene-tolerant in gene repression. Proc Natl Acad Sci U S A (2016) 0.84
Genome-wide characterisation and analysis of bHLH transcription factors related to tanshinone biosynthesis in Salvia miltiorrhiza. Sci Rep (2015) 0.83
DNA determinants in sequence-specific recognition by XmaI endonuclease. Nucleic Acids Res (1995) 0.81
CTGC motifs within the HIV core promoter specify Tat-responsive pre-initiation complexes. Retrovirology (2012) 0.80
The members of bHLH transcription factor superfamily are required for female reproduction in the red flour beetle, Tribolium castaneum. J Insect Physiol (2010) 0.80
The basic helix-loop-helix transcription factor family in the pea aphid, Acyrthosiphon pisum. J Insect Sci (2011) 0.78
A comparison of midline and tracheal gene regulation during Drosophila development. PLoS One (2014) 0.76
A Genome-Wide Identification and Analysis of the Basic Helix-Loop-Helix Transcription Factors in Brown Planthopper, Nilaparvata lugens. Genes (Basel) (2016) 0.75
Sequence-specific DNA binding by MYC/MAX to low-affinity non-E-box motifs. PLoS One (2017) 0.75
A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics (1989) 105.30
Transformation of intact yeast cells treated with alkali cations. J Bacteriol (1983) 100.26
The leucine zipper: a hypothetical structure common to a new class of DNA binding proteins. Science (1988) 27.01
Expression of a single transfected cDNA converts fibroblasts to myoblasts. Cell (1987) 22.17
A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins. Cell (1989) 21.54
Max: a helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc. Science (1991) 12.00
Differences and similarities in DNA-binding preferences of MyoD and E2A protein complexes revealed by binding site selection. Science (1990) 9.54
Scissors-grip model for DNA recognition by a family of leucine zipper proteins. Science (1989) 8.98
The human c-myc oncogene: structural consequences of translocation into the IgH locus in Burkitt lymphoma. Cell (1983) 8.54
The MyoD DNA binding domain contains a recognition code for muscle-specific gene activation. Cell (1990) 7.94
Sequence-specific DNA binding by the c-Myc protein. Science (1990) 7.75
The adenovirus major late transcription factor USF is a member of the helix-loop-helix group of regulatory proteins and binds to DNA as a dimer. Genes Dev (1990) 6.88
TFE3: a helix-loop-helix protein that activates transcription through the immunoglobulin enhancer muE3 motif. Genes Dev (1990) 6.00
Association of Myn, the murine homolog of max, with c-Myc stimulates methylation-sensitive DNA binding and ras cotransformation. Cell (1991) 5.76
Yeast centromere binding protein CBF1, of the helix-loop-helix protein family, is required for chromosome stability and methionine prototrophy. Cell (1990) 4.59
Methylation-sensitive sequence-specific DNA binding by the c-Myc basic region. Science (1991) 4.45
The gene SCL is expressed during early hematopoiesis and encodes a differentiation-related DNA-binding motif. Proc Natl Acad Sci U S A (1989) 4.22
CPF1, a yeast protein which functions in centromeres and promoters. EMBO J (1990) 3.65
Transcription factor AP-4 contains multiple dimerization domains that regulate dimer specificity. Genes Dev (1990) 3.44
Muscle-specific transcriptional activation by MyoD. Genes Dev (1991) 3.37
Isolation of the gene encoding the Saccharomyces cerevisiae centromere-binding protein CP1. Mol Cell Biol (1990) 3.24
Elements involved in S-adenosylmethionine-mediated regulation of the Saccharomyces cerevisiae MET25 gene. Mol Cell Biol (1989) 2.89
Design of DNA-binding peptides based on the leucine zipper motif. Science (1990) 2.84
Enhancer-binding activity of the tal-1 oncoprotein in association with the E47/E12 helix-loop-helix proteins. Mol Cell Biol (1991) 2.25
Determination of the c-MYC DNA-binding site. Proc Natl Acad Sci U S A (1991) 2.19
Mutagenesis of the myogenin basic region identifies an ancient protein motif critical for activation of myogenesis. Proc Natl Acad Sci U S A (1991) 2.08
Specific cis-acting sequence for PHO8 expression interacts with PHO4 protein, a positive regulatory factor, in Saccharomyces cerevisiae. Mol Cell Biol (1991) 1.14
c-Myc transactivation of LDH-A: implications for tumor metabolism and growth. Proc Natl Acad Sci U S A (1997) 5.43
A potential transcriptional activation element in the p53 protein. Oncogene (1990) 2.07
Intracellular leucine zipper interactions suggest c-Myc hetero-oligomerization. Mol Cell Biol (1991) 1.84
Karyoplasmic interaction selection strategy: a general strategy to detect protein-protein interactions in mammalian cells. Proc Natl Acad Sci U S A (1992) 1.60
Detection and quantitation of human papillomavirus (HPV) DNA in the sera of patients with HPV-associated head and neck squamous cell carcinoma. Clin Cancer Res (2000) 1.46
Activation domains of L-Myc and c-Myc determine their transforming potencies in rat embryo cells. Mol Cell Biol (1992) 1.39
Oncogenes in tumor metabolism, tumorigenesis, and apoptosis. J Bioenerg Biomembr (1997) 1.28
E2A basic-helix-loop-helix transcription factors are negatively regulated by serum growth factors and by the Id3 protein. Nucleic Acids Res (1996) 1.21
Mechanisms of hemolysis-associated platelet activation. J Thromb Haemost (2013) 1.17
A link between c-Myc-mediated transcriptional repression and neoplastic transformation. J Clin Invest (1996) 1.06
B-myc inhibits neoplastic transformation and transcriptional activation by c-myc. Mol Cell Biol (1993) 1.01
Near-infrared spectra absorbance of blood from sickle cell patients and normal individuals. Hematology (2009) 0.83
The mUBC9 murine ubiquitin conjugating enzyme interacts with the E2A transcription factors. Gene (1997) 0.81
Successful treatment of life-threatening acute chest syndrome of sickle cell disease with venovenous extracorporeal membrane oxygenation. J Pediatr Hematol Oncol (1997) 0.78
DNA binding by the Myc oncoproteins. Cancer Treat Res (1992) 0.76
Myc target genes in neoplastic transformation. Curr Top Microbiol Immunol (1997) 0.76
Steroid receptors, transcription factors, and gene expression. AACR special conference in cancer research. Cancer Res (1990) 0.75
Childhood Hodgkin and non-Hodgkin lymphomas. Pediatr Rev (1990) 0.75
Low-dose methotrexate therapy for hepatoblastoma. Cancer Chemother Pharmacol (1991) 0.75
Homozygous factor-V mutation as a genetic cause of perinatal thrombosis and cerebral palsy. Dev Med Child Neurol (1999) 0.75
Drug concentration-dependent DNA lesions are induced by the lipid-soluble antifolate, piritrexim (BW301U). Mol Pharmacol (1986) 0.75