Published in Nat Chem Biol on February 25, 2007
C9orf72 nucleotide repeat structures initiate molecular cascades of disease. Nature (2014) 3.59
Targeting G-quadruplexes in gene promoters: a novel anticancer strategy? Nat Rev Drug Discov (2011) 3.54
Human telomere, oncogenic promoter and 5'-UTR G-quadruplexes: diverse higher order DNA and RNA targets for cancer therapeutics. Nucleic Acids Res (2007) 3.49
Stability and kinetics of G-quadruplex structures. Nucleic Acids Res (2008) 2.75
5'-UTR RNA G-quadruplexes: translation regulation and targeting. Nucleic Acids Res (2012) 2.36
Conserved elements with potential to form polymorphic G-quadruplex structures in the first intron of human genes. Nucleic Acids Res (2008) 2.27
G-quadruplexes: the beginning and end of UTRs. Nucleic Acids Res (2008) 2.18
Antitumor activity and mechanism of action of the cyclopenta[b]benzofuran, silvestrol. PLoS One (2009) 2.11
C9orf72 hexanucleotide repeat associated with amyotrophic lateral sclerosis and frontotemporal dementia forms RNA G-quadruplexes. Sci Rep (2012) 2.09
Genomic distribution and functional analyses of potential G-quadruplex-forming sequences in Saccharomyces cerevisiae. Nucleic Acids Res (2007) 1.98
The disease-associated r(GGGGCC)n repeat from the C9orf72 gene forms tract length-dependent uni- and multimolecular RNA G-quadruplex structures. J Biol Chem (2013) 1.97
RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer. Nature (2014) 1.84
G-quadruplex nucleic acids as therapeutic targets. Curr Opin Chem Biol (2009) 1.74
Identification and characterization of nucleolin as a c-myc G-quadruplex-binding protein. J Biol Chem (2009) 1.72
Discrimination of common and unique RNA-binding activities among Fragile X mental retardation protein paralogs. Hum Mol Genet (2009) 1.53
5'-UTR G-quadruplex structures acting as translational repressors. Nucleic Acids Res (2010) 1.49
Visualization and selective chemical targeting of RNA G-quadruplex structures in the cytoplasm of human cells. Nat Chem (2013) 1.48
Structural insights into G-quadruplexes: towards new anticancer drugs. Future Med Chem (2010) 1.44
Structure-function studies of FMRP RGG peptide recognition of an RNA duplex-quadruplex junction. Nat Struct Mol Biol (2011) 1.38
Inhibition of translation in living eukaryotic cells by an RNA G-quadruplex motif. RNA (2008) 1.34
G4 resolvase 1 binds both DNA and RNA tetramolecular quadruplex with high affinity and is the major source of tetramolecular quadruplex G4-DNA and G4-RNA resolving activity in HeLa cell lysates. J Biol Chem (2008) 1.32
Structural diversity of triplet repeat RNAs. J Biol Chem (2010) 1.29
Role for G-quadruplex RNA binding by Epstein-Barr virus nuclear antigen 1 in DNA replication and metaphase chromosome attachment. J Virol (2009) 1.29
Evidence of genome-wide G4 DNA-mediated gene expression in human cancer cells. Nucleic Acids Res (2009) 1.28
Small-molecule-mediated G-quadruplex isolation from human cells. Nat Chem (2010) 1.26
GRSDB2 and GRS_UTRdb: databases of quadruplex forming G-rich sequences in pre-mRNAs and mRNAs. Nucleic Acids Res (2007) 1.24
Predicting and understanding the stability of G-quadruplexes. Bioinformatics (2009) 1.23
New roles of carboxypeptidase E in endocrine and neural function and cancer. Endocr Rev (2012) 1.23
Telomeric repeat-containing RNA structure in living cells. Proc Natl Acad Sci U S A (2010) 1.23
Deciphering the rules by which 5'-UTR sequences affect protein expression in yeast. Proc Natl Acad Sci U S A (2013) 1.18
c-MYC promoter G-quadruplex formed at the 5'-end of NHE III1 element: insights into biological relevance and parallel-stranded G-quadruplex stability. Nucleic Acids Res (2011) 1.18
Solution structure of a 2:1 quindoline-c-MYC G-quadruplex: insights into G-quadruplex-interactive small molecule drug design. J Am Chem Soc (2011) 1.17
A crystallographic and modelling study of a human telomeric RNA (TERRA) quadruplex. Nucleic Acids Res (2010) 1.16
Targeting human gastrointestinal stromal tumor cells with a quadruplex-binding small molecule. J Med Chem (2009) 1.15
A G-quadruplex structure within the 5'-UTR of TRF2 mRNA represses translation in human cells. Nucleic Acids Res (2010) 1.13
Role of the amino terminal RHAU-specific motif in the recognition and resolution of guanine quadruplex-RNA by the DEAH-box RNA helicase RHAU. Nucleic Acids Res (2010) 1.13
Predictable suppression of gene expression by 5'-UTR-based RNA quadruplexes. Nucleic Acids Res (2009) 1.11
Small molecule-mediated inhibition of translation by targeting a native RNA G-quadruplex. Org Biomol Chem (2010) 1.11
Quartets in G-major. The First International Meeting on Quadruplex DNA. EMBO Rep (2007) 1.11
An intramolecular G-quadruplex structure is required for binding of telomeric repeat-containing RNA to the telomeric protein TRF2. J Am Chem Soc (2012) 1.11
The BCL-2 5' untranslated region contains an RNA G-quadruplex-forming motif that modulates protein expression. Biochemistry (2010) 1.11
Molecular crowding creates an essential environment for the formation of stable G-quadruplexes in long double-stranded DNA. Nucleic Acids Res (2009) 1.10
Macrocyclic and helical oligoamides as a new class of G-quadruplex ligands. J Am Chem Soc (2007) 1.10
Non-coding RNA Generated following Lariat Debranching Mediates Targeting of AID to DNA. Cell (2015) 1.10
G4 motifs correlate with promoter-proximal transcriptional pausing in human genes. Nucleic Acids Res (2011) 1.09
G4 resolvase 1 tightly binds and unwinds unimolecular G4-DNA. Nucleic Acids Res (2011) 1.09
The quadruplex r(CGG)n destabilizing cationic porphyrin TMPyP4 cooperates with hnRNPs to increase the translation efficiency of fragile X premutation mRNA. Nucleic Acids Res (2009) 1.08
Cellular strategies for regulating functional and nonfunctional protein aggregation. Cell Rep (2012) 1.08
The tetraplex (CGG)n destabilizing proteins hnRNP A2 and CBF-A enhance the in vivo translation of fragile X premutation mRNA. Nucleic Acids Res (2007) 1.08
G-quadruplexes regulate Epstein-Barr virus-encoded nuclear antigen 1 mRNA translation. Nat Chem Biol (2014) 1.07
Selective RNA versus DNA G-quadruplex targeting by in situ click chemistry. Angew Chem Int Ed Engl (2012) 1.07
Exploring mRNA 3'-UTR G-quadruplexes: evidence of roles in both alternative polyadenylation and mRNA shortening. Nucleic Acids Res (2013) 1.07
Distinct functions of maternal and somatic Pat1 protein paralogs. RNA (2010) 1.06
Pyridostatin analogues promote telomere dysfunction and long-term growth inhibition in human cancer cells. Org Biomol Chem (2012) 1.05
Microsatellite tandem repeats are abundant in human promoters and are associated with regulatory elements. PLoS One (2013) 1.04
A sequence-independent analysis of the loop length dependence of intramolecular RNA G-quadruplex stability and topology. Biochemistry (2011) 1.04
The DEAH-box RNA helicase RHAU binds an intramolecular RNA G-quadruplex in TERC and associates with telomerase holoenzyme. Nucleic Acids Res (2011) 1.04
Replication protein A unfolds G-quadruplex structures with varying degrees of efficiency. J Phys Chem B (2012) 1.02
A thermodynamic overview of naturally occurring intramolecular DNA quadruplexes. Nucleic Acids Res (2008) 1.02
Crystal structure of a c-kit promoter quadruplex reveals the structural role of metal ions and water molecules in maintaining loop conformation. Nucleic Acids Res (2012) 1.01
An RNA hairpin to G-quadruplex conformational transition. J Am Chem Soc (2012) 1.00
G-quadruplex DNA as a molecular target for induced synthetic lethality in cancer cells. J Am Chem Soc (2013) 0.98
Position and stability are determining factors for translation repression by an RNA G-quadruplex-forming sequence within the 5' UTR of the NRAS proto-oncogene. Biochemistry (2008) 0.98
QGRS-H Predictor: a web server for predicting homologous quadruplex forming G-rich sequence motifs in nucleotide sequences. Nucleic Acids Res (2012) 0.97
In vivo veritas: using yeast to probe the biological functions of G-quadruplexes. Biochimie (2008) 0.97
The porphyrin TmPyP4 unfolds the extremely stable G-quadruplex in MT3-MMP mRNA and alleviates its repressive effect to enhance translation in eukaryotic cells. Nucleic Acids Res (2012) 0.97
Genomic features of the human dopamine transporter gene and its potential epigenetic States: implications for phenotypic diversity. PLoS One (2010) 0.96
Loop and backbone modifications of peptide nucleic acid improve g-quadruplex binding selectivity. J Am Chem Soc (2009) 0.96
G-quadruplexes in viruses: function and potential therapeutic applications. Nucleic Acids Res (2014) 0.95
A toolbox for predicting g-quadruplex formation and stability. J Nucleic Acids (2010) 0.94
Structure of long telomeric RNA transcripts: the G-rich RNA forms a compact repeating structure containing G-quartets. J Biol Chem (2009) 0.94
FRAXE-associated mental retardation protein (FMR2) is an RNA-binding protein with high affinity for G-quartet RNA forming structure. Nucleic Acids Res (2009) 0.94
Insight into G-DNA structural polymorphism and folding from sequence and loop connectivity through free energy analysis. J Am Chem Soc (2011) 0.94
Use of competition dialysis in the discovery of G-quadruplex selective ligands. Methods (2007) 0.93
RNA G-Quadruplexes in the model plant species Arabidopsis thaliana: prevalence and possible functional roles. Nucleic Acids Res (2010) 0.92
Higher-order RNA structural requirements and small-molecule induction of tombusvirus subgenomic mRNA transcription. J Virol (2008) 0.92
RPA-mediated unfolding of systematically varying G-quadruplex structures. Biophys J (2013) 0.92
Binding of G-quadruplexes to the N-terminal recognition domain of the RNA helicase associated with AU-rich element (RHAU). J Biol Chem (2013) 0.92
U3 region in the HIV-1 genome adopts a G-quadruplex structure in its RNA and DNA sequence. Biochemistry (2014) 0.92
Insights into the mechanism of a G-quadruplex-unwinding DEAH-box helicase. Nucleic Acids Res (2015) 0.91
RecQ-core of BLM unfolds telomeric G-quadruplex in the absence of ATP. Nucleic Acids Res (2014) 0.91
Translational repression of the disintegrin and metalloprotease ADAM10 by a stable G-quadruplex secondary structure in its 5'-untranslated region. J Biol Chem (2011) 0.90
Role of conserved cis-regulatory elements in the post-transcriptional regulation of the human MECP2 gene involved in autism. Hum Genomics (2013) 0.89
FMRP interacts with G-quadruplex structures in the 3'-UTR of its dendritic target Shank1 mRNA. RNA Biol (2014) 0.89
Identification and characterization of RNA guanine-quadruplex binding proteins. Nucleic Acids Res (2014) 0.89
Telomeric G-quadruplexes are a substrate and site of localization for human telomerase. Nat Commun (2015) 0.88
G-quadruplex formation enhances splicing efficiency of PAX9 intron 1. Hum Genet (2014) 0.87
Insights into G-quadruplex specific recognition by the DEAH-box helicase RHAU: Solution structure of a peptide-quadruplex complex. Proc Natl Acad Sci U S A (2015) 0.87
G-quadruplexes: from guanine gels to chemotherapeutics. Mol Biotechnol (2011) 0.87
G-quadruplex recognition by bis-indole carboxamides. Chem Commun (Camb) (2008) 0.87
A G-quadruplex stabilizer induces M-phase cell cycle arrest. J Biol Chem (2009) 0.87
A GAG trinucleotide-repeat polymorphism in the gene for glutathione biosynthetic enzyme, GCLC, affects gene expression through translation. FASEB J (2011) 0.86
Investigation of mRNA quadruplex formation in Escherichia coli. Nat Protoc (2009) 0.85
Sequence, stability, and structure of G-quadruplexes and their interactions with drugs. Curr Protoc Nucleic Acid Chem (2012) 0.85
QGRS-Conserve: a computational method for discovering evolutionarily conserved G-quadruplex motifs. Hum Genomics (2014) 0.85
Translational repression of cyclin D3 by a stable G-quadruplex in its 5' UTR: implications for cell cycle regulation. RNA Biol (2012) 0.84
Mapping the sequences of potential guanine quadruplex motifs. Nucleic Acids Res (2011) 0.84
Aven recognition of RNA G-quadruplexes regulates translation of the mixed lineage leukemia protooncogenes. Elife (2015) 0.84
Stimulation of ribosomal frameshifting by RNA G-quadruplex structures. Nucleic Acids Res (2013) 0.83
A highly conserved G-rich consensus sequence in hepatitis C virus core gene represents a new anti-hepatitis C target. Sci Adv (2016) 0.83
ras genes. Annu Rev Biochem (1987) 22.59
Targeting RAS signalling pathways in cancer therapy. Nat Rev Cancer (2003) 15.17
Structural features in eukaryotic mRNAs that modulate the initiation of translation. J Biol Chem (1991) 11.92
Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription. Proc Natl Acad Sci U S A (2002) 9.60
Prevalence of quadruplexes in the human genome. Nucleic Acids Res (2005) 7.79
Telomere end-binding proteins control the formation of G-quadruplex DNA structures in vivo. Nat Struct Mol Biol (2005) 4.61
Following G-quartet formation by UV-spectroscopy. FEBS Lett (1998) 4.08
Telomere maintenance as a target for anticancer drug discovery. Nat Rev Drug Discov (2002) 3.32
Hairpin and parallel quartet structures for telomeric sequences. Nucleic Acids Res (1992) 3.03
Analysis of thermal melting curves. Oligonucleotides (2003) 2.84
Human N-ras: cDNA cloning and gene structure. Nucleic Acids Res (1985) 2.41
Cation-dependent transition between the quadruplex and Watson-Crick hairpin forms of d(CGCG3GCG). Biochemistry (1992) 2.22
The effect of chemical modifications on the thermal stability of different G-quadruplex-forming oligonucleotides. Nucleic Acids Res (2005) 2.04
Translational control of growth factor and proto-oncogene expression. Int J Biochem Cell Biol (1999) 1.54
Engineering the quadruplex fold: nucleoside conformation determines both folding topology and molecularity in guanine quadruplexes. J Am Chem Soc (2006) 1.49
Suppression of oncogenic NRAS by RNA interference induces apoptosis of human melanoma cells. Int J Cancer (2005) 1.37
Utility of firefly luciferase as a reporter gene for promoter activity in transgenic mice. Nucleic Acids Res (1988) 1.21
Accurate whole human genome sequencing using reversible terminator chemistry. Nature (2008) 90.20
Prevalence of quadruplexes in the human genome. Nucleic Acids Res (2005) 7.79
G-quadruplexes in promoters throughout the human genome. Nucleic Acids Res (2006) 5.84
Quantitative sequencing of 5-methylcytosine and 5-hydroxymethylcytosine at single-base resolution. Science (2012) 5.17
Quantitative visualization of DNA G-quadruplex structures in human cells. Nat Chem (2013) 4.61
Putative DNA quadruplex formation within the human c-kit oncogene. J Am Chem Soc (2005) 3.28
Loop-length-dependent folding of G-quadruplexes. J Am Chem Soc (2004) 3.16
Studies on the structure and dynamics of the human telomeric G quadruplex by single-molecule fluorescence resonance energy transfer. Proc Natl Acad Sci U S A (2003) 2.82
LIN-28 and the poly(U) polymerase PUP-2 regulate let-7 microRNA processing in Caenorhabditis elegans. Nat Struct Mol Biol (2009) 2.79
A conserved quadruplex motif located in a transcription activation site of the human c-kit oncogene. Biochemistry (2006) 2.62
Small-molecule-induced DNA damage identifies alternative DNA structures in human genes. Nat Chem Biol (2012) 2.41
5'-UTR RNA G-quadruplexes: translation regulation and targeting. Nucleic Acids Res (2012) 2.36
G-quadruplexes: the beginning and end of UTRs. Nucleic Acids Res (2008) 2.18
Genome-wide distribution of 5-formylcytosine in embryonic stem cells is associated with transcription and depends on thymine DNA glycosylase. Genome Biol (2012) 1.94
FANCJ is a structure-specific DNA helicase associated with the maintenance of genomic G/C tracts. J Biol Chem (2008) 1.93
A novel small molecule that alters shelterin integrity and triggers a DNA-damage response at telomeres. J Am Chem Soc (2008) 1.91
Template-assisted fabrication of salt-independent catalytic tubular microengines. ACS Nano (2010) 1.90
Trisubstituted isoalloxazines as a new class of G-quadruplex binding ligands: small molecule regulation of c-kit oncogene expression. J Am Chem Soc (2007) 1.87
The transcription factor FOXM1 is a cellular target of the natural product thiostrepton. Nat Chem (2011) 1.82
A sequence-independent study of the influence of short loop lengths on the stability and topology of intramolecular DNA G-quadruplexes. Biochemistry (2007) 1.75
G-quadruplex structures are stable and detectable in human genomic DNA. Nat Commun (2013) 1.72
Ultrasensitive coincidence fluorescence detection of single DNA molecules. Anal Chem (2003) 1.60
Oxidative bisulfite sequencing of 5-methylcytosine and 5-hydroxymethylcytosine. Nat Protoc (2013) 1.54
Kinetics of unfolding the human telomeric DNA quadruplex using a PNA trap. J Am Chem Soc (2003) 1.51
A screen for hydroxymethylcytosine and formylcytosine binding proteins suggests functions in transcription and chromatin regulation. Genome Biol (2013) 1.50
FANCJ coordinates two pathways that maintain epigenetic stability at G-quadruplex DNA. Nucleic Acids Res (2011) 1.45
A single-molecule platform for investigation of interactions between G-quadruplexes and small-molecule ligands. Nat Chem (2011) 1.43
A proton-fuelled DNA nanomachine. Angew Chem Int Ed Engl (2003) 1.42
A G-rich sequence within the c-kit oncogene promoter forms a parallel G-quadruplex having asymmetric G-tetrad dynamics. J Am Chem Soc (2009) 1.40
Formation of an interlocked quadruplex dimer by d(GGGT). J Am Chem Soc (2004) 1.37
Genome-wide mapping of FOXM1 binding reveals co-binding with estrogen receptor alpha in breast cancer cells. Genome Biol (2013) 1.31
Small-molecule-mediated G-quadruplex isolation from human cells. Nat Chem (2010) 1.26
Single-molecule conformational analysis of G-quadruplex formation in the promoter DNA duplex of the proto-oncogene c-kit. J Am Chem Soc (2007) 1.25
Oxazole-based peptide macrocycles: a new class of G-quadruplex binding ligands. J Am Chem Soc (2006) 1.20
Identification of a new RNA.RNA interaction site for human telomerase RNA (hTR): structural implications for hTR accumulation and a dyskeratosis congenita point mutation. Nucleic Acids Res (2003) 1.19
Determination of the fraction and stoichiometry of femtomolar levels of biomolecular complexes in an excess of monomer using single-molecule, two-color coincidence detection. Anal Chem (2006) 1.17
G-quadruplex-specific peptide-hemicyanine ligands by partial combinatorial selection. J Am Chem Soc (2003) 1.16
Single-molecule analysis of human telomerase monomer. Nat Chem Biol (2008) 1.16
Genome-wide analysis of a G-quadruplex-specific single-chain antibody that regulates gene expression. Nucleic Acids Res (2009) 1.15
Motion-based DNA detection using catalytic nanomotors. Nat Commun (2010) 1.15
Ligand-driven G-quadruplex conformational switching by using an unusual mode of interaction. Angew Chem Int Ed Engl (2007) 1.15
Rudimentary G-quadruplex-based telomere capping in Saccharomyces cerevisiae. Nat Struct Mol Biol (2011) 1.14
A non-canonical DNA structure is a binding motif for the transcription factor SP1 in vitro. Nucleic Acids Res (2011) 1.12
Small molecule-mediated inhibition of translation by targeting a native RNA G-quadruplex. Org Biomol Chem (2010) 1.11
An intramolecular G-quadruplex structure is required for binding of telomeric repeat-containing RNA to the telomeric protein TRF2. J Am Chem Soc (2012) 1.11
The BCL-2 5' untranslated region contains an RNA G-quadruplex-forming motif that modulates protein expression. Biochemistry (2010) 1.11
Macrocyclic and helical oligoamides as a new class of G-quadruplex ligands. J Am Chem Soc (2007) 1.10
Molecule by molecule direct and quantitative counting of antibody-protein complexes in solution. Anal Chem (2004) 1.10
Rapid delivery of drug carriers propelled and navigated by catalytic nanoshuttles. Small (2010) 1.10
Binding interactions between long noncoding RNA HOTAIR and PRC2 proteins. Biochemistry (2013) 1.09
Structural analysis of the catalytic core of human telomerase RNA by FRET and molecular modeling. Biochemistry (2006) 1.08
A LIN28-dependent structural change in pre-let-7g directly inhibits dicer processing. Biochemistry (2011) 1.08
DNA molecular motor driven micromechanical cantilever arrays. J Am Chem Soc (2005) 1.07
Selective RNA versus DNA G-quadruplex targeting by in situ click chemistry. Angew Chem Int Ed Engl (2012) 1.07
A reversible pH-driven DNA nanoswitch array. J Am Chem Soc (2006) 1.07
Distinct functions of maternal and somatic Pat1 protein paralogs. RNA (2010) 1.06
Minimum length requirement of the alignment domain of human telomerase RNA to sustain catalytic activity in vitro. Nucleic Acids Res (2002) 1.05
Pyridostatin analogues promote telomere dysfunction and long-term growth inhibition in human cancer cells. Org Biomol Chem (2012) 1.05
G-quadruplex-binding benzo[a]phenoxazines down-regulate c-KIT expression in human gastric carcinoma cells. J Am Chem Soc (2011) 1.05
A sequence-independent analysis of the loop length dependence of intramolecular RNA G-quadruplex stability and topology. Biochemistry (2011) 1.04
Measuring single-molecule nucleic acid dynamics in solution by two-color filtered ratiometric fluorescence correlation spectroscopy. Proc Natl Acad Sci U S A (2004) 1.04
Exploring the differential recognition of DNA G-quadruplex targets by small molecules using dynamic combinatorial chemistry. Angew Chem Int Ed Engl (2008) 1.03
The kinetics and folding pathways of intramolecular G-quadruplex nucleic acids. J Am Chem Soc (2012) 1.03
Selective recognition of a DNA G-quadruplex by an engineered antibody. Biochemistry (2008) 1.02
Tetramethylpyridiniumporphyrazines--a new class of G-quadruplex inducing and stabilising ligands. Chem Commun (Camb) (2006) 1.02
Exploring the recognition of quadruplex DNA by an engineered Cys2-His2 zinc finger protein. Biochemistry (2006) 1.02
An RNA hairpin to G-quadruplex conformational transition. J Am Chem Soc (2012) 1.00
A PNA4 quadruplex. J Am Chem Soc (2004) 1.00
G-quadruplex DNA as a molecular target for induced synthetic lethality in cancer cells. J Am Chem Soc (2013) 0.98
Position and stability are determining factors for translation repression by an RNA G-quadruplex-forming sequence within the 5' UTR of the NRAS proto-oncogene. Biochemistry (2008) 0.98
Inhibition of human telomerase activity by an engineered zinc finger protein that binds G-quadruplexes. Biochemistry (2004) 0.98
Triarylpyridines: a versatile small molecule scaffold for G-quadruplex recognition. Chem Commun (Camb) (2008) 0.97
Direct visualization of G-quadruplexes in DNA using atomic force microscopy. Nucleic Acids Res (2009) 0.97
G-quadruplex DNA bound by a synthetic ligand is highly dynamic. J Am Chem Soc (2009) 0.95
Functionalized micromachines for selective and rapid isolation of nucleic acid targets from complex samples. Nano Lett (2011) 0.95
Solid-phase methods for the synthesis of cyanine dyes. J Org Chem (2005) 0.95
Diarylethynyl amides that recognize the parallel conformation of genomic promoter DNA G-quadruplexes. J Am Chem Soc (2008) 0.94
Highly sensitive phage-based biosensor for the detection of beta-galactosidase. Anal Chim Acta (2007) 0.93
A small molecule that disrupts G-quadruplex DNA structure and enhances gene expression. J Am Chem Soc (2009) 0.93
Templated ligand assembly by using G-quadruplex DNA and dynamic covalent chemistry. Angew Chem Int Ed Engl (2004) 0.92
Investigating a quadruplex-ligand interaction by unfolding kinetics. J Am Chem Soc (2006) 0.91
Experimental approaches to identify cellular G-quadruplex structures and functions. Methods (2012) 0.91
Formation and abundance of 5-hydroxymethylcytosine in RNA. Chembiochem (2015) 0.91
Dynamic covalent chemistry on self-templating peptides: formation of a disulfide-linked beta-hairpin mimic. Angew Chem Int Ed Engl (2003) 0.90
Analysis of human telomerase activity and function by two color single molecule coincidence fluorescence spectroscopy. J Am Chem Soc (2006) 0.89
RNA conformation in catalytically active human telomerase. J Am Chem Soc (2010) 0.89
Electrochemically-triggered motion of catalytic nanomotors. Chem Commun (Camb) (2009) 0.87
Synthesis and G-quadruplex binding studies of new 4-N-methylpyridinium porphyrins. Org Biomol Chem (2006) 0.87
Targeting the single-strand G-rich overhang of telomeres with PNA inhibits cell growth and induces apoptosis of human immortal cells. Exp Cell Res (2004) 0.87
G-quadruplex recognition by bis-indole carboxamides. Chem Commun (Camb) (2008) 0.87
Controlled-folding of a small molecule modulates DNA G-quadruplex recognition. Chem Commun (Camb) (2008) 0.86
Chemical sensing based on catalytic nanomotors: motion-based detection of trace silver. J Am Chem Soc (2009) 0.86