Published in J Am Chem Soc on September 23, 2009
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Downregulation of oncogenic RAS and c-Myc expression in MOLT-4 leukaemia cells by a salicylaldehyde semicarbazone copper(II) complex. Sci Rep (2016) 0.75
A core extended naphtalene diimide G-quadruplex ligand potently inhibits herpes simplex virus 1 replication. Sci Rep (2017) 0.75
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Putative DNA quadruplex formation within the human c-kit oncogene. J Am Chem Soc (2005) 3.28
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Two-repeat human telomeric d(TAGGGTTAGGGT) sequence forms interconverting parallel and antiparallel G-quadruplexes in solution: distinct topologies, thermodynamic properties, and folding/unfolding kinetics. J Am Chem Soc (2003) 2.52
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Structure of two intramolecular G-quadruplexes formed by natural human telomere sequences in K+ solution. Nucleic Acids Res (2007) 2.09
NMR solution structure of the major G-quadruplex structure formed in the human BCL2 promoter region. Nucleic Acids Res (2006) 2.03
The importance of negative superhelicity in inducing the formation of G-quadruplex and i-motif structures in the c-Myc promoter: implications for drug targeting and control of gene expression. J Med Chem (2009) 2.03
The structures of quadruplex nucleic acids and their drug complexes. Curr Opin Struct Biol (2009) 2.01
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Trisubstituted isoalloxazines as a new class of G-quadruplex binding ligands: small molecule regulation of c-kit oncogene expression. J Am Chem Soc (2007) 1.87
Structure and regulation of Kit protein-tyrosine kinase--the stem cell factor receptor. Biochem Biophys Res Commun (2005) 1.85
A site-specific low-enrichment (15)N,(13)C isotope-labeling approach to unambiguous NMR spectral assignments in nucleic acids. J Am Chem Soc (2002) 1.77
A sequence-independent study of the influence of short loop lengths on the stability and topology of intramolecular DNA G-quadruplexes. Biochemistry (2007) 1.75
An interlocked dimeric parallel-stranded DNA quadruplex: a potent inhibitor of HIV-1 integrase. Proc Natl Acad Sci U S A (2005) 1.71
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(3 + 1) Assembly of three human telomeric repeats into an asymmetric dimeric G-quadruplex. J Am Chem Soc (2005) 1.51
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Single-molecule conformational analysis of G-quadruplex formation in the promoter DNA duplex of the proto-oncogene c-kit. J Am Chem Soc (2007) 1.25
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KIT oncoprotein interactions in gastrointestinal stromal tumors: therapeutic relevance. Oncogene (2007) 0.95
Diarylethynyl amides that recognize the parallel conformation of genomic promoter DNA G-quadruplexes. J Am Chem Soc (2008) 0.94
Selectivity in ligand recognition of G-quadruplex loops. Biochemistry (2009) 0.94
Topology variation and loop structural homology in crystal and simulated structures of a bimolecular DNA quadruplex. J Am Chem Soc (2006) 0.93
Probing the role of hydrogen bonds in the stability of base pairs in double-helical DNA. Biopolymers (2007) 0.92
Inhibition of myc promoter and telomerase activity and induction of delayed apoptosis by SYUIQ-5, a novel G-quadruplex interactive agent in leukemia cells. Leukemia (2007) 0.90
Possibility of an antiparallel (tetramer) quadruplex exhibited by the double repeat of the human telomere. Biochemistry (2007) 0.87
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Quantitative sequencing of 5-methylcytosine and 5-hydroxymethylcytosine at single-base resolution. Science (2012) 5.17
Quantitative visualization of DNA G-quadruplex structures in human cells. Nat Chem (2013) 4.61
An RNA G-quadruplex in the 5' UTR of the NRAS proto-oncogene modulates translation. Nat Chem Biol (2007) 4.11
Targeting G-quadruplexes in gene promoters: a novel anticancer strategy? Nat Rev Drug Discov (2011) 3.54
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An intramolecular G-quadruplex structure is required for binding of telomeric repeat-containing RNA to the telomeric protein TRF2. J Am Chem Soc (2012) 1.11
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Macrocyclic and helical oligoamides as a new class of G-quadruplex ligands. J Am Chem Soc (2007) 1.10
Molecule by molecule direct and quantitative counting of antibody-protein complexes in solution. Anal Chem (2004) 1.10
A role for water molecules in DNA-ligand minor groove recognition. Acc Chem Res (2009) 1.10
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Structural analysis of the catalytic core of human telomerase RNA by FRET and molecular modeling. Biochemistry (2006) 1.08