Published in J Biol Chem on October 07, 2008
5'-UTR RNA G-quadruplexes: translation regulation and targeting. Nucleic Acids Res (2012) 2.36
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Discrimination of common and unique RNA-binding activities among Fragile X mental retardation protein paralogs. Hum Mol Genet (2009) 1.53
5'-UTR G-quadruplex structures acting as translational repressors. Nucleic Acids Res (2010) 1.49
Visualization and selective chemical targeting of RNA G-quadruplex structures in the cytoplasm of human cells. Nat Chem (2013) 1.48
Role of the amino terminal RHAU-specific motif in the recognition and resolution of guanine quadruplex-RNA by the DEAH-box RNA helicase RHAU. Nucleic Acids Res (2010) 1.13
Non-coding RNA Generated following Lariat Debranching Mediates Targeting of AID to DNA. Cell (2015) 1.10
G4 resolvase 1 tightly binds and unwinds unimolecular G4-DNA. Nucleic Acids Res (2011) 1.09
The RNA helicase RHAU (DHX36) unwinds a G4-quadruplex in human telomerase RNA and promotes the formation of the P1 helix template boundary. Nucleic Acids Res (2012) 1.05
The 5' guanosine tracts of human telomerase RNA are recognized by the G-quadruplex binding domain of the RNA helicase DHX36 and function to increase RNA accumulation. Mol Cell Biol (2010) 1.04
A sequence-independent analysis of the loop length dependence of intramolecular RNA G-quadruplex stability and topology. Biochemistry (2011) 1.04
The DEAH-box RNA helicase RHAU binds an intramolecular RNA G-quadruplex in TERC and associates with telomerase holoenzyme. Nucleic Acids Res (2011) 1.04
DHX36 enhances RIG-I signaling by facilitating PKR-mediated antiviral stress granule formation. PLoS Pathog (2014) 1.01
DNA and RNA quadruplex-binding proteins. Int J Mol Sci (2014) 1.01
Yin Yang 1 contains G-quadruplex structures in its promoter and 5'-UTR and its expression is modulated by G4 resolvase 1. Nucleic Acids Res (2011) 0.97
G-quadruplexes in viruses: function and potential therapeutic applications. Nucleic Acids Res (2014) 0.95
G-quadruplex conformation and dynamics are determined by loop length and sequence. Nucleic Acids Res (2014) 0.93
Telomere lengthening and other functions of telomerase. Acta Naturae (2012) 0.92
Binding of G-quadruplexes to the N-terminal recognition domain of the RNA helicase associated with AU-rich element (RHAU). J Biol Chem (2013) 0.92
Insights into the mechanism of a G-quadruplex-unwinding DEAH-box helicase. Nucleic Acids Res (2015) 0.91
MOV10 and FMRP regulate AGO2 association with microRNA recognition elements. Cell Rep (2014) 0.91
Translational repression of the disintegrin and metalloprotease ADAM10 by a stable G-quadruplex secondary structure in its 5'-untranslated region. J Biol Chem (2011) 0.90
G-quadruplexes and helicases. Nucleic Acids Res (2016) 0.90
Primary respiratory chain disease causes tissue-specific dysregulation of the global transcriptome and nutrient-sensing signaling network. PLoS One (2013) 0.88
A parallel quadruplex DNA is bound tightly but unfolded slowly by pif1 helicase. J Biol Chem (2015) 0.85
RNA G-quadruplexes are globally unfolded in eukaryotic cells and depleted in bacteria. Science (2016) 0.85
The RNA helicase RHAU (DHX36) suppresses expression of the transcription factor PITX1. Nucleic Acids Res (2013) 0.84
The biology of DHX9 and its potential as a therapeutic target. Oncotarget (2016) 0.84
Aven recognition of RNA G-quadruplexes regulates translation of the mixed lineage leukemia protooncogenes. Elife (2015) 0.84
The guanine-quadruplex structure in the human c-myc gene's promoter is converted into B-DNA form by the human poly(ADP-ribose)polymerase-1. PLoS One (2012) 0.83
Single-molecule imaging reveals a common mechanism shared by G-quadruplex-resolving helicases. Proc Natl Acad Sci U S A (2016) 0.82
A targeted oligonucleotide enhancer of SMN2 exon 7 splicing forms competing quadruplex and protein complexes in functional conditions. Cell Rep (2014) 0.81
A G-quadruplex DNA structure resolvase, RHAU, is essential for spermatogonia differentiation. Cell Death Dis (2015) 0.81
Optimal antisense target reducing INS intron 1 retention is adjacent to a parallel G quadruplex. Nucleic Acids Res (2014) 0.80
Put on your thinking cap: G-quadruplexes, helicases, and telomeres. Aging (Albany NY) (2011) 0.80
Simultaneous binding to the tracking strand, displaced strand and the duplex of a DNA fork enhances unwinding by Dda helicase. Nucleic Acids Res (2014) 0.79
Biophysical Characterization of G-Quadruplex Recognition in the PITX1 mRNA by the Specificity Domain of the Helicase RHAU. PLoS One (2015) 0.78
RNA G-quadruplexes: emerging mechanisms in disease. Nucleic Acids Res (2016) 0.78
RNA Helicase Associated with AU-rich Element (RHAU/DHX36) Interacts with the 3'-Tail of the Long Non-coding RNA BC200 (BCYRN1). J Biol Chem (2016) 0.75
Regulating infidelity: RNA-mediated recruitment of AID to DNA during class switch recombination. Eur J Immunol (2016) 0.75
RNA Secondary Structure Modulates FMRP's Bi-Functional Role in the MicroRNA Pathway. Int J Mol Sci (2016) 0.75
RNA G-quadruplexes and their potential regulatory roles in translation. Translation (Austin) (2016) 0.75
RHAU helicase stabilizes G4 in its nucleotide-free state and destabilizes G4 upon ATP hydrolysis. Nucleic Acids Res (2016) 0.75
Fluorophore ligand binding and complex stabilization of the RNA Mango and RNA Spinach aptamers. RNA (2016) 0.75
Mutational Dissection of Telomeric DNA Binding Requirements of G4 Resolvase 1 Shows that G4-Structure and Certain 3'-Tail Sequences Are Sufficient for Tight and Complete Binding. PLoS One (2015) 0.75
Evidence That G-quadruplex DNA Accumulates in the Cytoplasm and Participates in Stress Granule Assembly in Response to Oxidative Stress. J Biol Chem (2016) 0.75
RNA G-quadruplexes in biology: Principles and molecular mechanisms. J Mol Biol (2017) 0.75
Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription. Proc Natl Acad Sci U S A (2002) 9.60
Crystal structure of parallel quadruplexes from human telomeric DNA. Nature (2002) 8.90
Formation of parallel four-stranded complexes by guanine-rich motifs in DNA and its implications for meiosis. Nature (1988) 8.58
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G-quadruplexes in promoters throughout the human genome. Nucleic Acids Res (2006) 5.84
Highly prevalent putative quadruplex sequence motifs in human DNA. Nucleic Acids Res (2005) 5.34
A mouse cytoplasmic exoribonuclease (mXRN1p) with preference for G4 tetraplex substrates. J Cell Biol (1997) 4.93
The Bloom's syndrome helicase unwinds G4 DNA. J Biol Chem (1998) 4.67
G-quartets 40 years later: from 5'-GMP to molecular biology and supramolecular chemistry. Angew Chem Int Ed Engl (2004) 4.20
An RNA G-quadruplex in the 5' UTR of the NRAS proto-oncogene modulates translation. Nat Chem Biol (2007) 4.11
DNA tetraplex formation in the control region of c-myc. Nucleic Acids Res (1998) 4.09
In vitro generated antibodies specific for telomeric guanine-quadruplex DNA react with Stylonychia lemnae macronuclei. Proc Natl Acad Sci U S A (2001) 3.97
Disruption of dog-1 in Caenorhabditis elegans triggers deletions upstream of guanine-rich DNA. Nat Genet (2002) 3.50
BACH1 is critical for homologous recombination and appears to be the Fanconi anemia gene product FANCJ. Cancer Cell (2005) 3.44
Human werner syndrome DNA helicase unwinds tetrahelical structures of the fragile X syndrome repeat sequence d(CGG)n. J Biol Chem (1999) 3.39
Intracellular transcription of G-rich DNAs induces formation of G-loops, novel structures containing G4 DNA. Genes Dev (2004) 3.36
Gene function correlates with potential for G4 DNA formation in the human genome. Nucleic Acids Res (2006) 3.13
Regulation of murine telomere length by Rtel: an essential gene encoding a helicase-like protein. Cell (2004) 2.91
FANCJ helicase defective in Fanconia anemia and breast cancer unwinds G-quadruplex DNA to defend genomic stability. Mol Cell Biol (2008) 2.88
Four-stranded nucleic acid structures 25 years later: from guanosine gels to telomer DNA. J Biomol Struct Dyn (1990) 2.62
Conserved elements with potential to form polymorphic G-quadruplex structures in the first intron of human genes. Nucleic Acids Res (2008) 2.27
The effect of chemical modifications on the thermal stability of different G-quadruplex-forming oligonucleotides. Nucleic Acids Res (2005) 2.04
Downstream sequence elements with different affinities for the hnRNP H/H' protein influence the processing efficiency of mammalian polyadenylation signals. Nucleic Acids Res (2002) 2.00
Different loop arrangements of intramolecular human telomeric (3+1) G-quadruplexes in K+ solution. Nucleic Acids Res (2006) 1.98
High affinity interactions of nucleolin with G-G-paired rDNA. J Biol Chem (1999) 1.73
Telomerase recruitment by the telomere end binding protein-beta facilitates G-quadruplex DNA unfolding in ciliates. Nat Struct Mol Biol (2008) 1.72
Characterization of the G-quadruplexes in the duplex nuclease hypersensitive element of the PDGF-A promoter and modulation of PDGF-A promoter activity by TMPyP4. Nucleic Acids Res (2007) 1.66
Unusual DNA structure of the diabetes susceptibility locus IDDM2 and its effect on transcription by the insulin promoter factor Pur-1/MAZ. Proc Natl Acad Sci U S A (2000) 1.59
GRSDB: a database of quadruplex forming G-rich sequences in alternatively processed mammalian pre-mRNA sequences. Nucleic Acids Res (2006) 1.54
Formation of pseudosymmetrical G-quadruplex and i-motif structures in the proximal promoter region of the RET oncogene. J Am Chem Soc (2007) 1.53
G4 DNA binding by LR1 and its subunits, nucleolin and hnRNP D, A role for G-G pairing in immunoglobulin switch recombination. J Biol Chem (1999) 1.49
Facilitation of mRNA deadenylation and decay by the exosome-bound, DExH protein RHAU. Mol Cell (2004) 1.48
Functional and dysfunctional roles of quadruplex DNA in cells. Chem Biol (2001) 1.43
The DEXH protein product of the DHX36 gene is the major source of tetramolecular quadruplex G4-DNA resolving activity in HeLa cell lysates. J Biol Chem (2005) 1.35
Multiple functions of nuclear DNA helicase II (RNA helicase A) in nucleic acid metabolism. Acta Biochim Biophys Sin (Shanghai) (2004) 1.19
Transcription-dependent nucleolar cap localization and possible nuclear function of DExH RNA helicase RHAU. Exp Cell Res (2008) 1.06
Insulin capture by an insulin-linked polymorphic region G-quadruplex DNA oligonucleotide. J Am Chem Soc (2006) 1.05
The identification and characterization of a G4-DNA resolvase activity. J Biol Chem (1997) 1.03
Inhibition of DNA synthesis by K+-stabilised G-quadruplex promotes allelic preferential amplification. FEBS Lett (2004) 0.87
Polygenic model of DNA repair genetic polymorphisms in human breast cancer risk. Carcinogenesis (2008) 1.64
Facilitation of mRNA deadenylation and decay by the exosome-bound, DExH protein RHAU. Mol Cell (2004) 1.48
Stabilization of urokinase and urokinase receptor mRNAs by HuR is linked to its cytoplasmic accumulation induced by activated mitogen-activated protein kinase-activated protein kinase 2. Mol Cell Biol (2003) 1.42
Development of Herceptin resistance in breast cancer cells. Cytometry A (2004) 1.39
The DEXH protein product of the DHX36 gene is the major source of tetramolecular quadruplex G4-DNA resolving activity in HeLa cell lysates. J Biol Chem (2005) 1.35
Isoform-specific knockdown and expression of adaptor protein ShcA using small interfering RNA. Biochem J (2002) 1.30
Interactions between immunity, proliferation and molecular subtype in breast cancer prognosis. Genome Biol (2013) 1.26
Role of the amino terminal RHAU-specific motif in the recognition and resolution of guanine quadruplex-RNA by the DEAH-box RNA helicase RHAU. Nucleic Acids Res (2010) 1.13
G4 resolvase 1 tightly binds and unwinds unimolecular G4-DNA. Nucleic Acids Res (2011) 1.09
Recruitment of the RNA helicase RHAU to stress granules via a unique RNA-binding domain. J Biol Chem (2008) 1.08
p66shc inhibits pro-survival epidermal growth factor receptor/ERK signaling during severe oxidative stress in mouse renal proximal tubule cells. J Biol Chem (2008) 1.06
Transcription-dependent nucleolar cap localization and possible nuclear function of DExH RNA helicase RHAU. Exp Cell Res (2008) 1.06
Breast tumor cells isolated from in vitro resistance to trastuzumab remain sensitive to trastuzumab anti-tumor effects in vivo and to ADCC killing. Cancer Immunol Immunother (2009) 1.05
The DEAH-box RNA helicase RHAU binds an intramolecular RNA G-quadruplex in TERC and associates with telomerase holoenzyme. Nucleic Acids Res (2011) 1.04
p66SHC-mediated mitochondrial dysfunction in renal proximal tubule cells during oxidative injury. Am J Physiol Renal Physiol (2010) 1.00
The N2-ethylguanine and the O6-ethyl- and O6-methylguanine lesions in DNA: contrasting responses from the "bypass" DNA polymerase eta and the replicative DNA polymerase alpha. Chem Res Toxicol (2003) 0.99
AU-rich elements and alternative splicing in the beta-catenin 3'UTR can influence the human beta-catenin mRNA stability. Exp Cell Res (2006) 0.99
Replication of N2-ethyldeoxyguanosine DNA adducts in the human embryonic kidney cell line 293. Chem Res Toxicol (2006) 0.98
Yin Yang 1 plays an essential role in breast cancer and negatively regulates p27. Am J Pathol (2012) 0.98
Yin Yang 1 contains G-quadruplex structures in its promoter and 5'-UTR and its expression is modulated by G4 resolvase 1. Nucleic Acids Res (2011) 0.97
Understanding key assay parameters that affect measurements of trastuzumab-mediated ADCC against Her2 positive breast cancer cells. Oncoimmunology (2012) 0.97
Serine/threonine phosphorylation of ShcA. Regulation of protein-tyrosine phosphatase-pest binding and involvement in insulin signaling. J Biol Chem (2002) 0.94
Plasminogen activator inhibitor type-1 inhibits insulin signaling by competing with alphavbeta3 integrin for vitronectin binding. Eur J Biochem (2003) 0.92
The adenovirus E4orf6 protein inhibits DNA double strand break repair and radiosensitizes human tumor cells in an E1B-55K-independent manner. J Biol Chem (2004) 0.90
Cisplatin induces apoptosis through the ERK-p66shc pathway in renal proximal tubule cells. Cancer Lett (2010) 0.90
Oxidative DNA base damage in MCF-10A breast epithelial cells at clinically achievable concentrations of doxorubicin. Biochem Pharmacol (2007) 0.90
Identification and modulation of a caveolae-dependent signal pathway that regulates plasminogen activator inhibitor-1 in insulin-resistant adipocytes. Proc Natl Acad Sci U S A (2004) 0.86
The DEAH-box helicase RHAU is an essential gene and critical for mouse hematopoiesis. Blood (2012) 0.86
Mutagenesis by exocyclic alkylamino purine adducts in Escherichia coli. Mutat Res (2006) 0.85
Induction of uPA gene expression by the blockage of E-cadherin via Src- and Shc-dependent Erk signaling. FEBS J (2007) 0.83
Regulation of PAI-1 gene expression during adipogenesis. J Cell Biochem (2007) 0.82
Non-redundant role of Shc in Erk activation by cytoskeletal reorganization. J Biol Chem (2003) 0.82
Detection and characterization of a glutathione conjugate of ochratoxin A. Chem Res Toxicol (2002) 0.81
Fatty acid metabolites in rapidly proliferating breast cancer. PLoS One (2013) 0.78
Oral paricalcitol (19-nor-1,25-dihydroxyvitamin D2) in women receiving chemotherapy for metastatic breast cancer: a feasibility trial. Cancer Biol Ther (2013) 0.77
Stoichiometric preference in copper-promoted oxidative DNA damage by ochratoxin A. J Inorg Biochem (2003) 0.76
Regulation of protease and protease inhibitor gene expression: the role of the 3'-UTR and lessons from the plasminogen activating system. Prog Nucleic Acid Res Mol Biol (2005) 0.75