Published in Mol Biol Cell on March 07, 2007
An oncogenomics-based in vivo RNAi screen identifies tumor suppressors in liver cancer. Cell (2008) 5.47
Anchoring junctions as drug targets: role in contraceptive development. Pharmacol Rev (2008) 1.76
A role for the cleaved cytoplasmic domain of E-cadherin in the nucleus. J Biol Chem (2008) 1.32
The catenin family at a glance. J Cell Sci (2010) 1.24
Kruppel-like zinc finger protein Glis2 is essential for the maintenance of normal renal functions. Mol Cell Biol (2008) 1.10
Junctional music that the nucleus hears: cell-cell contact signaling and the modulation of gene activity. Cold Spring Harb Perspect Biol (2009) 1.09
p120 catenin: an essential regulator of cadherin stability, adhesion-induced signaling, and cancer progression. Prog Mol Biol Transl Sci (2013) 1.04
Gli-similar (Glis) Krüppel-like zinc finger proteins: insights into their physiological functions and critical roles in neonatal diabetes and cystic renal disease. Histol Histopathol (2010) 1.04
Gene array and fluorescence in situ hybridization biomarkers of activity of saracatinib (AZD0530), a Src inhibitor, in a preclinical model of colorectal cancer. Clin Cancer Res (2010) 0.96
The evolutionary history of the catenin gene family during metazoan evolution. BMC Evol Biol (2011) 0.95
Gli-similar proteins: their mechanisms of action, physiological functions, and roles in disease. Vitam Horm (2012) 0.95
Comparative proteomic analysis of plasma membrane proteins between human osteosarcoma and normal osteoblastic cell lines. BMC Cancer (2010) 0.93
Out, in and back again: PtdIns(4,5)P(2) regulates cadherin trafficking in epithelial morphogenesis. Biochem J (2009) 0.91
Nuclear signaling from cadherin adhesion complexes. Curr Top Dev Biol (2015) 0.90
Identification of nuclear localization, DNA binding, and transactivating mechanisms of Kruppel-like zinc finger protein Gli-similar 2 (Glis2). J Biol Chem (2010) 0.89
A complex of BBS1 and NPHP7 is required for cilia motility in zebrafish. PLoS One (2013) 0.88
Beyond β-catenin: prospects for a larger catenin network in the nucleus. Nat Rev Mol Cell Biol (2015) 0.87
From cell membrane to the nucleus: an emerging role of E-cadherin in gene transcriptional regulation. J Cell Mol Med (2014) 0.84
P120 catenin represses transcriptional activity through Kaiso in endothelial cells. Microvasc Res (2010) 0.84
Interaction with the Bardet-Biedl gene product TRIM32/BBS11 modifies the half-life and localization of Glis2/NPHP7. J Biol Chem (2014) 0.84
Loss of p120 catenin upregulates transcription of pro-inflammatory adhesion molecules in human endothelial cells. Microvasc Res (2011) 0.82
p120-catenin regulates REST and CoREST, and modulates mouse embryonic stem cell differentiation. J Cell Sci (2014) 0.81
DIPA-family coiled-coils bind conserved isoform-specific head domain of p120-catenin family: potential roles in hydrocephalus and heterotopia. Mol Biol Cell (2014) 0.81
Beta-catenin versus the other armadillo catenins: assessing our current view of canonical Wnt signaling. Prog Mol Biol Transl Sci (2013) 0.80
An in vivo screen to identify candidate neurogenic genes in the developing Xenopus visual system. Dev Biol (2015) 0.79
Caspase-3 cleavage links delta-catenin to the novel nuclear protein ZIFCAT. J Biol Chem (2011) 0.79
Up-regulation of Glis2 involves in neuronal apoptosis after intracerebral hemorrhage in adult rats. Cell Mol Neurobiol (2014) 0.79
Phosphorylation and isoform use in p120-catenin during development and tumorigenesis. Biochim Biophys Acta (2015) 0.77
A central role for cadherin signaling in cancer. Exp Cell Res (2017) 0.75
SUMOylation Blocks the Ubiquitin-Mediated Degradation of the Nephronophthisis Gene Product Glis2/NPHP7. PLoS One (2015) 0.75
Structural characterization of CAS SH3 domain selectivity and regulation reveals new CAS interaction partners. Sci Rep (2017) 0.75
Hedgehog signaling in animal development: paradigms and principles. Genes Dev (2001) 14.75
Regulation of cadherin-mediated adhesion in morphogenesis. Nat Rev Mol Cell Biol (2005) 9.27
A homolog of the armadillo protein in Drosophila (plakoglobin) associated with E-cadherin. Science (1991) 5.71
Hakai, a c-Cbl-like protein, ubiquitinates and induces endocytosis of the E-cadherin complex. Nat Cell Biol (2002) 5.02
A core function for p120-catenin in cadherin turnover. J Cell Biol (2003) 4.85
Intercellular adhesion, signalling and the cytoskeleton. Nat Cell Biol (2002) 4.29
Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb. Nature (1998) 4.14
Wnt signaling: is the party in the nucleus? Genes Dev (2006) 4.10
A novel role for p120 catenin in E-cadherin function. J Cell Biol (2002) 4.01
Selective uncoupling of p120(ctn) from E-cadherin disrupts strong adhesion. J Cell Biol (2000) 3.88
Balancing cell adhesion and Wnt signaling, the key role of beta-catenin. Curr Opin Genet Dev (2005) 3.79
The p300/CBP acetyltransferases function as transcriptional coactivators of beta-catenin in vertebrates. EMBO J (2000) 3.77
Identification of a new catenin: the tyrosine kinase substrate p120cas associates with E-cadherin complexes. Mol Cell Biol (1994) 3.66
p120 catenin regulates the actin cytoskeleton via Rho family GTPases. J Cell Biol (2000) 3.60
Signaling from Smo to Ci/Gli: conservation and divergence of Hedgehog pathways from Drosophila to vertebrates. Development (2006) 3.39
Cellular levels of p120 catenin function as a set point for cadherin expression levels in microvascular endothelial cells. J Cell Biol (2003) 3.39
Inhibition of RhoA by p120 catenin. Nat Cell Biol (2000) 3.33
Specification of neuronal fates in the ventral neural tube. Curr Opin Neurobiol (2001) 3.11
The catenin p120(ctn) interacts with Kaiso, a novel BTB/POZ domain zinc finger transcription factor. Mol Cell Biol (1999) 3.02
The p120 catenin partner Kaiso is a DNA methylation-dependent transcriptional repressor. Genes Dev (2001) 2.91
'Shocking' developments in chick embryology: electroporation and in ovo gene expression. Nat Cell Biol (1999) 2.87
Kaiso/p120-catenin and TCF/beta-catenin complexes coordinately regulate canonical Wnt gene targets. Dev Cell (2005) 2.86
Proteolysis of the Hedgehog signaling effector Cubitus interruptus requires phosphorylation by Glycogen Synthase Kinase 3 and Casein Kinase 1. Cell (2002) 2.73
p120, a novel substrate of protein tyrosine kinase receptors and of p60v-src, is related to cadherin-binding factors beta-catenin, plakoglobin and armadillo. Oncogene (1992) 2.49
Coupling of Gab1 to c-Met, Grb2, and Shp2 mediates biological responses. J Cell Biol (2000) 2.48
Transducing Hedgehog: the story so far. EMBO J (1998) 2.44
p120 catenin affects cell motility via modulation of activity of Rho-family GTPases: a link between cell-cell contact formation and regulation of cell locomotion. J Cell Sci (2001) 2.40
Tomosyn: a syntaxin-1-binding protein that forms a novel complex in the neurotransmitter release process. Neuron (1998) 2.36
Direct cadherin-activated cell signaling: a view from the plasma membrane. J Cell Biol (2002) 2.33
Rap1 regulates the formation of E-cadherin-based cell-cell contacts. Mol Cell Biol (2004) 2.31
Dorsal-ventral patterning of the spinal cord requires Gli3 transcriptional repressor activity. Genes Dev (2002) 2.10
p120 catenin regulates dendritic spine and synapse development through Rho-family GTPases and cadherins. Neuron (2006) 2.10
p120 catenin associates with kinesin and facilitates the transport of cadherin-catenin complexes to intercellular junctions. J Cell Biol (2003) 2.02
The p120(ctn)-binding partner Kaiso is a bi-modal DNA-binding protein that recognizes both a sequence-specific consensus and methylated CpG dinucleotides. Nucleic Acids Res (2002) 2.02
Cadherin-mediated cellular signaling. Curr Opin Cell Biol (2003) 1.80
Characterization of the human suppressor of fused, a negative regulator of the zinc-finger transcription factor Gli. J Cell Sci (1999) 1.74
Non-canonical Wnt signals are modulated by the Kaiso transcriptional repressor and p120-catenin. Nat Cell Biol (2004) 1.73
p120(ctn) acts as an inhibitory regulator of cadherin function in colon carcinoma cells. J Cell Biol (1999) 1.70
A gradient of Gli activity mediates graded Sonic Hedgehog signaling in the neural tube. Genes Dev (2005) 1.68
Nuclear localization of the p120(ctn) Armadillo-like catenin is counteracted by a nuclear export signal and by E-cadherin expression. Proc Natl Acad Sci U S A (1999) 1.56
A novel interaction between kinesin and p120 modulates p120 localization and function. J Biol Chem (2003) 1.43
G protein-coupled receptor kinase 5 contains a DNA-binding nuclear localization sequence. Mol Cell Biol (2004) 1.32
NLS-dependent nuclear localization of p120ctn is necessary to relieve Kaiso-mediated transcriptional repression. J Cell Sci (2004) 1.25
Characterization of Glis2, a novel gene encoding a Gli-related, Krüppel-like transcription factor with transactivation and repressor functions. Roles in kidney development and neurogenesis. J Biol Chem (2001) 1.24
p120 catenin associates with microtubules: inverse relationship between microtubule binding and Rho GTPase regulation. J Biol Chem (2003) 1.18
Identification of NKL, a novel Gli-Kruppel zinc-finger protein that promotes neuronal differentiation. Development (2001) 1.17
Regulation of p120-catenin nucleocytoplasmic shuttling activity. J Cell Sci (2003) 1.17
p120 catenin and phosphorylation: Mechanisms and traits of an unresolved issue. Biochim Biophys Acta (2006) 1.13
Krüppel-like zinc finger protein Gli-similar 2 (Glis2) represses transcription through interaction with C-terminal binding protein 1 (CtBP1). Nucleic Acids Res (2005) 1.02
The N-terminal basic domain of human parvulin hPar14 is responsible for the entry to the nucleus and high-affinity DNA-binding. J Mol Biol (2002) 0.94
Basic and acidic regions flanking the HMG domain of maize HMGa modulate the interactions with DNA and the self-association of the protein. Biochemistry (1998) 0.85
A human protein-protein interaction network: a resource for annotating the proteome. Cell (2005) 18.97
Met, metastasis, motility and more. Nat Rev Mol Cell Biol (2003) 14.30
Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumors. Mol Cell Biol (2002) 8.60
Wnt signalling and its impact on development and cancer. Nat Rev Cancer (2008) 8.37
PRIDE: the proteomics identifications database. Proteomics (2005) 7.52
Canonical Wnt/beta-catenin signaling prevents osteoblasts from differentiating into chondrocytes. Dev Cell (2005) 6.90
Targeting MET in cancer: rationale and progress. Nat Rev Cancer (2012) 6.43
Hakai, a c-Cbl-like protein, ubiquitinates and induces endocytosis of the E-cadherin complex. Nat Cell Biol (2002) 5.02
Cutaneous cancer stem cell maintenance is dependent on beta-catenin signalling. Nature (2008) 4.60
Deciphering the function of canonical Wnt signals in development and disease: conditional loss- and gain-of-function mutations of beta-catenin in mice. Genes Dev (2008) 4.38
Human Proteinpedia enables sharing of human protein data. Nat Biotechnol (2008) 4.21
Proteomics analyses reveal the evolutionary conservation and divergence of N-terminal acetyltransferases from yeast and humans. Proc Natl Acad Sci U S A (2009) 4.09
Hematopoietic stem cell and multilineage defects generated by constitutive beta-catenin activation. Nat Immunol (2006) 3.98
Mutations in the desmosomal protein plakophilin-2 are common in arrhythmogenic right ventricular cardiomyopathy. Nat Genet (2004) 3.88
Balancing cell adhesion and Wnt signaling, the key role of beta-catenin. Curr Opin Genet Dev (2005) 3.79
Morphological and biochemical characterization of a human liver in a uPA-SCID mouse chimera. Hepatology (2005) 3.72
Mesenchymal stem cells are recruited into wounded skin and contribute to wound repair by transdifferentiation into multiple skin cell type. J Immunol (2008) 3.67
Improved visualization of protein consensus sequences by iceLogo. Nat Methods (2009) 3.64
beta-Catenin is required for specification of proximal/distal cell fate during lung morphogenesis. J Biol Chem (2003) 3.37
Large-scale identification of N-terminal peptides in the halophilic archaea Halobacterium salinarum and Natronomonas pharaonis. J Proteome Res (2007) 3.30
Pattern formation in the vertebrate neural tube: a sonic hedgehog morphogen-regulated transcriptional network. Development (2008) 3.30
The interpretation of morphogen gradients. Development (2006) 3.28
Interplay of cadherin-mediated cell adhesion and canonical Wnt signaling. Cold Spring Harb Perspect Biol (2010) 3.02
MACC1, a newly identified key regulator of HGF-MET signaling, predicts colon cancer metastasis. Nat Med (2008) 3.00
Essential role of BCL9-2 in the switch between beta-catenin's adhesive and transcriptional functions. Genes Dev (2004) 2.99
Interpretation of the sonic hedgehog morphogen gradient by a temporal adaptation mechanism. Nature (2007) 2.97
beta-Catenin signals regulate cell growth and the balance between progenitor cell expansion and differentiation in the nervous system. Dev Biol (2003) 2.85
Caspase-14 protects against epidermal UVB photodamage and water loss. Nat Cell Biol (2007) 2.82
Expression of DeltaNLef1 in mouse epidermis results in differentiation of hair follicles into squamous epidermal cysts and formation of skin tumours. Development (2002) 2.79
Long-term, multilineage hematopoiesis occurs in the combined absence of beta-catenin and gamma-catenin. Blood (2007) 2.78
Wnt/beta-catenin signaling acts upstream of N-myc, BMP4, and FGF signaling to regulate proximal-distal patterning in the lung. Dev Biol (2005) 2.73
The transcriptional control of trunk neural crest induction, survival, and delamination. Dev Cell (2005) 2.67
Targeted peptidecentric proteomics reveals caspase-7 as a substrate of the caspase-1 inflammasomes. Mol Cell Proteomics (2008) 2.64
The role of Axin2 in calvarial morphogenesis and craniosynostosis. Development (2005) 2.63
Neural crest development is regulated by the transcription factor Sox9. Development (2003) 2.62
Listeria monocytogenes impairs SUMOylation for efficient infection. Nature (2010) 2.57
Gene regulatory logic for reading the Sonic Hedgehog signaling gradient in the vertebrate neural tube. Cell (2012) 2.54
LRRK2 controls an EndoA phosphorylation cycle in synaptic endocytosis. Neuron (2012) 2.49
Involvement of Lgl and Mahjong/VprBP in cell competition. PLoS Biol (2010) 2.45
LNCipedia: a database for annotated human lncRNA transcript sequences and structures. Nucleic Acids Res (2012) 2.40
The miR-17-92 microRNA cluster regulates multiple components of the TGF-β pathway in neuroblastoma. Mol Cell (2010) 2.38
Role of beta-catenin in synaptic vesicle localization and presynaptic assembly. Neuron (2003) 2.37
Helicobacter pylori CagA protein targets the c-Met receptor and enhances the motogenic response. J Cell Biol (2003) 2.37
Wnt signaling in stem and cancer stem cells. Curr Opin Cell Biol (2013) 2.35
Caspase-specific and nonspecific in vivo protein processing during Fas-induced apoptosis. Nat Methods (2005) 2.33
Rap1 regulates the formation of E-cadherin-based cell-cell contacts. Mol Cell Biol (2004) 2.31
Identification and functional characterization of N-terminally acetylated proteins in Drosophila melanogaster. PLoS Biol (2009) 2.25
Continuous tooth generation in mouse is induced by activated epithelial Wnt/beta-catenin signaling. Proc Natl Acad Sci U S A (2006) 2.25
Characterization of the interface between normal and transformed epithelial cells. Nat Cell Biol (2009) 2.21
Lysosomal targeting of E-cadherin: a unique mechanism for the down-regulation of cell-cell adhesion during epithelial to mesenchymal transitions. Mol Cell Biol (2005) 2.19
Protein N-terminal acetyltransferases: when the start matters. Trends Biochem Sci (2012) 2.19
Reciprocal requirements for EDA/EDAR/NF-kappaB and Wnt/beta-catenin signaling pathways in hair follicle induction. Dev Cell (2009) 2.17
Dorsal-ventral patterning of the spinal cord requires Gli3 transcriptional repressor activity. Genes Dev (2002) 2.10
The kinesin protein Kif7 is a critical regulator of Gli transcription factors in mammalian hedgehog signaling. Sci Signal (2009) 2.05
The ankyrin repeat protein Diversin recruits Casein kinase Iepsilon to the beta-catenin degradation complex and acts in both canonical Wnt and Wnt/JNK signaling. Genes Dev (2002) 2.02
Deletion of beta-catenin impairs T cell development. Nat Immunol (2003) 2.01
Analysis of protein processing by N-terminal proteomics reveals novel species-specific substrate determinants of granzyme B orthologs. Mol Cell Proteomics (2008) 2.01
c-Met is essential for wound healing in the skin. J Cell Biol (2007) 1.98
Global analysis of the mitochondrial N-proteome identifies a processing peptidase critical for protein stability. Cell (2009) 1.96
E-cadherin is crucial for embryonic stem cell pluripotency and can replace OCT4 during somatic cell reprogramming. EMBO Rep (2011) 1.93
Caspase-14 is required for filaggrin degradation to natural moisturizing factors in the skin. J Invest Dermatol (2011) 1.93
Requirement of plakophilin 2 for heart morphogenesis and cardiac junction formation. J Cell Biol (2004) 1.92
Improved recovery of proteome-informative, protein N-terminal peptides by combined fractional diagonal chromatography (COFRADIC). Proteomics (2008) 1.81
Wnt signaling in stem and cancer stem cells. Semin Cell Dev Biol (2010) 1.79
Inhibition of neural crest migration underlies craniofacial dysmorphology and Hirschsprung's disease in Bardet-Biedl syndrome. Proc Natl Acad Sci U S A (2008) 1.78
How to make tubes: signaling by the Met receptor tyrosine kinase. Trends Cell Biol (2003) 1.77
Regulated and polarized PtdIns(3,4,5)P3 accumulation is essential for apical membrane morphogenesis in photoreceptor epithelial cells. Curr Biol (2006) 1.77
SOX9 induces and maintains neural stem cells. Nat Neurosci (2010) 1.74
The metastasis-associated gene S100A4 is a novel target of beta-catenin/T-cell factor signaling in colon cancer. Gastroenterology (2006) 1.73
Beta-catenin regulates Cripto- and Wnt3-dependent gene expression programs in mouse axis and mesoderm formation. Development (2003) 1.73
The floor plate: multiple cells, multiple signals. Nat Rev Neurosci (2005) 1.71
Gli proteins and the control of spinal-cord patterning. EMBO Rep (2003) 1.68
A gradient of Gli activity mediates graded Sonic Hedgehog signaling in the neural tube. Genes Dev (2005) 1.68
Evidence for licensing of IFN-gamma-induced IFN regulatory factor 1 transcription factor by MyD88 in Toll-like receptor-dependent gene induction program. Proc Natl Acad Sci U S A (2006) 1.68
Aberrant Wnt/beta-catenin signaling can induce chromosomal instability in colon cancer. Proc Natl Acad Sci U S A (2006) 1.64
Morphogens and the control of cell proliferation and patterning in the spinal cord. Cell Cycle (2007) 1.63
Distinct roles of Wnt/beta-catenin and Bmp signaling during early cardiogenesis. Proc Natl Acad Sci U S A (2007) 1.60
Otx2 regulates subtype specification and neurogenesis in the midbrain. J Neurosci (2005) 1.59
Dynamic assignment and maintenance of positional identity in the ventral neural tube by the morphogen sonic hedgehog. PLoS Biol (2010) 1.58
The tyrosine phosphatase Shp2 in development and cancer. Adv Cancer Res (2010) 1.58
NatF contributes to an evolutionary shift in protein N-terminal acetylation and is important for normal chromosome segregation. PLoS Genet (2011) 1.57
Selection of multipotent stem cells during morphogenesis of small intestinal crypts of Lieberkuhn is perturbed by stimulation of Lef-1/beta-catenin signaling. J Biol Chem (2002) 1.56
Genetic interaction between Wnt/beta-catenin and BMP receptor signaling during formation of the AER and the dorsal-ventral axis in the limb. Genes Dev (2003) 1.55
Interaction with surrounding normal epithelial cells influences signalling pathways and behaviour of Src-transformed cells. J Cell Sci (2009) 1.55
Oncogenicity of the developmental transcription factor Sox9. Cancer Res (2012) 1.55
A fluorescent reporter of caspase activity for live imaging. Proc Natl Acad Sci U S A (2008) 1.55
Specific inhibitors of the protein tyrosine phosphatase Shp2 identified by high-throughput docking. Proc Natl Acad Sci U S A (2008) 1.54
A colorectal cancer expression profile that includes transforming growth factor beta inhibitor BAMBI predicts metastatic potential. Gastroenterology (2009) 1.52
Improving the reliability and throughput of mass spectrometry-based proteomics by spectrum quality filtering. Proteomics (2006) 1.52
T-cell receptor-induced JNK activation requires proteolytic inactivation of CYLD by MALT1. EMBO J (2011) 1.52
Distinct Sonic Hedgehog signaling dynamics specify floor plate and ventral neuronal progenitors in the vertebrate neural tube. Genes Dev (2010) 1.51
A novel interaction between kinesin and p120 modulates p120 localization and function. J Biol Chem (2003) 1.43
The chicken talpid3 gene encodes a novel protein essential for Hedgehog signaling. Genes Dev (2006) 1.42
Establishing and interpreting graded Sonic Hedgehog signaling during vertebrate neural tube patterning: the role of negative feedback. Cold Spring Harb Perspect Biol (2009) 1.41