Published in BMC Genomics on March 10, 2007
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An overview of STRUCTURE: applications, parameter settings, and supporting software. Front Genet (2013) 1.02
Population substructure in Finland and Sweden revealed by the use of spatial coordinates and a small number of unlinked autosomal SNPs. BMC Genet (2008) 1.02
The twin questions of personalized medicine: who are you and whom do you most resemble? Genome Med (2009) 0.92
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Population genetic structure of variable drug response. Nat Genet (2001) 6.35
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Bayesian analysis of genetic differentiation between populations. Genetics (2003) 5.74
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Evidence for gradients of human genetic diversity within and among continents. Genome Res (2004) 4.70
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The African diaspora: mitochondrial DNA and the Atlantic slave trade. Am J Hum Genet (2004) 2.63
Proportioning whole-genome single-nucleotide-polymorphism diversity for the identification of geographic population structure and genetic ancestry. Am J Hum Genet (2006) 1.76
Dissecting racial and ethnic differences. N Engl J Med (2006) 1.19
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Discovering statistically significant pathways in expression profiling studies. Proc Natl Acad Sci U S A (2005) 8.75
A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers. Nat Genet (2006) 7.16
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The Shared Health Research Information Network (SHRINE): a prototype federated query tool for clinical data repositories. J Am Med Inform Assoc (2009) 6.49
A mega-analysis of genome-wide association studies for major depressive disorder. Mol Psychiatry (2012) 6.34
Creation and implications of a phenome-genome network. Nat Biotechnol (2006) 5.79
Tectonic shifts in the health information economy. N Engl J Med (2008) 5.42
Sequence-matched probes produce increased cross-platform consistency and more reproducible biological results in microarray-based gene expression measurements. Nucleic Acids Res (2004) 4.43
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Cluster analysis of gene expression dynamics. Proc Natl Acad Sci U S A (2002) 3.83
Distinctive patterns of microRNA expression in primary muscular disorders. Proc Natl Acad Sci U S A (2007) 3.72
Redefinition of Affymetrix probe sets by sequence overlap with cDNA microarray probes reduces cross-platform inconsistencies in cancer-associated gene expression measurements. BMC Bioinformatics (2005) 3.66
MAPPER: a search engine for the computational identification of putative transcription factor binding sites in multiple genomes. BMC Bioinformatics (2005) 3.23
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Gene expression signature with independent prognostic significance in epithelial ovarian cancer. J Clin Oncol (2004) 2.91
Systematic survey reveals general applicability of "guilt-by-association" within gene coexpression networks. BMC Bioinformatics (2005) 2.83
Local myocardial insulin-like growth factor 1 (IGF-1) delivery with biotinylated peptide nanofibers improves cell therapy for myocardial infarction. Proc Natl Acad Sci U S A (2006) 2.75
Gene expression comparison of biopsies from Duchenne muscular dystrophy (DMD) and normal skeletal muscle. Proc Natl Acad Sci U S A (2002) 2.60
NHLBI strategic visioning: setting an agenda together for the NHLBI of 2025. Am J Respir Crit Care Med (2015) 2.60
Network-based analysis of affected biological processes in type 2 diabetes models. PLoS Genet (2007) 2.54
The tell-tale heart: population-based surveillance reveals an association of rofecoxib and celecoxib with myocardial infarction. PLoS One (2007) 2.52
Quantifying the relationship between co-expression, co-regulation and gene function. BMC Bioinformatics (2004) 2.51
The SMART Platform: early experience enabling substitutable applications for electronic health records. J Am Med Inform Assoc (2012) 2.48
Expression profiling and identification of novel genes involved in myogenic differentiation. FASEB J (2003) 2.30
A submission model for use in the indexing, searching, and retrieval of distributed pathology case and tissue specimens. Stud Health Technol Inform (2004) 2.28
Minimal haplotype tagging. Proc Natl Acad Sci U S A (2003) 2.28
Ontology engineering. Nat Biotechnol (2010) 2.24
Direct determination of molecular haplotypes by chromosome microdissection. Nat Methods (2010) 2.21
Selective disruption of PPARgamma 2 impairs the development of adipose tissue and insulin sensitivity. Proc Natl Acad Sci U S A (2004) 2.21
Reproducibility of gene expression across generations of Affymetrix microarrays. BMC Bioinformatics (2003) 2.20
Prediction of chronic obstructive pulmonary disease (COPD) in asthma patients using electronic medical records. J Am Med Inform Assoc (2009) 2.20
Conserved mechanisms across development and tumorigenesis revealed by a mouse development perspective of human cancers. Genes Dev (2004) 2.16
Comprehensive dissection of PDGF-PDGFR signaling pathways in PDGFR genetically defined cells. PLoS One (2008) 2.10
The PING personally controlled electronic medical record system: technical architecture. J Am Med Inform Assoc (2004) 2.01
Rapid identification of myocardial infarction risk associated with diabetes medications using electronic medical records. Diabetes Care (2009) 2.00
GO PaD: the Gene Ontology Partition Database. Nucleic Acids Res (2006) 1.98
Escaping the EHR trap--the future of health IT. N Engl J Med (2012) 1.96
Technical desiderata for the integration of genomic data into Electronic Health Records. J Biomed Inform (2011) 1.96
An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge. Genome Biol (2014) 1.95
Disparities in trends of hospitalization for potentially preventable chronic conditions among African Americans during the 1990s: implications and benchmarks. Am J Public Health (2003) 1.94
Finding the missing link for big biomedical data. JAMA (2014) 1.90
A self-scaling, distributed information architecture for public health, research, and clinical care. J Am Med Inform Assoc (2007) 1.88
Transcriptomic analysis of human lung development. Am J Respir Crit Care Med (2009) 1.87
SHRINE: enabling nationally scalable multi-site disease studies. PLoS One (2013) 1.80
The MAPPER database: a multi-genome catalog of putative transcription factor binding sites. Nucleic Acids Res (2005) 1.80
Does collocation inform the impact of collaboration? PLoS One (2010) 1.78
Schottky solar cells based on colloidal nanocrystal films. Nano Lett (2008) 1.73
The asthma kiosk: a patient-centered technology for collaborative decision support in the emergency department. J Am Med Inform Assoc (2004) 1.70
A unified inference procedure for a class of measures to assess improvement in risk prediction systems with survival data. Stat Med (2012) 1.70
Optimization and evaluation of surface-enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI-TOF MS) with reversed-phase protein arrays for protein profiling. Clin Chem Lab Med (2005) 1.68
Parents as partners in obtaining the medication history. J Am Med Inform Assoc (2005) 1.67
Structural, optical, and electrical properties of self-assembled films of PbSe nanocrystals treated with 1,2-ethanedithiol. ACS Nano (2008) 1.63
Optimal deconvolution of transcriptional profiling data using quadratic programming with application to complex clinical blood samples. PLoS One (2011) 1.62
The MedSeq Project: a randomized trial of integrating whole genome sequencing into clinical medicine. Trials (2014) 1.62
A system for sharing routine surgical pathology specimens across institutions: the Shared Pathology Informatics Network. Hum Pathol (2007) 1.59
Effect of acute aldosterone administration on gene expression profile in the heart. Endocrinology (2006) 1.58
Antidepressant response in patients with major depression exposed to NSAIDs: a pharmacovigilance study. Am J Psychiatry (2012) 1.57
Multiple exciton generation in colloidal silicon nanocrystals. Nano Lett (2007) 1.56
DNA microarray profiling to identify angiotensin-responsive genes in vascular smooth muscle cells: potential mediators of vascular disease. Circ Res (2003) 1.55
Determinants of Notch-3 receptor expression and signaling in vascular smooth muscle cells: implications in cell-cycle regulation. Circ Res (2002) 1.55
AJC editor's consensus: psoriasis and coronary artery disease. Am J Cardiol (2008) 1.54
Training the next generation of informaticians: the impact of "BISTI" and bioinformatics--a report from the American College of Medical Informatics. J Am Med Inform Assoc (2004) 1.53
Bayesian approach to discovering pathogenic SNPs in conserved protein domains. Hum Mutat (2004) 1.51
Inter-species differences of co-expression of neighboring genes in eukaryotic genomes. BMC Genomics (2004) 1.50
Toward more transparent and reproducible omics studies through a common metadata checklist and data publications. OMICS (2014) 1.49
Defective ribosomal protein gene expression alters transcription, translation, apoptosis, and oncogenic pathways in Diamond-Blackfan anemia. Stem Cells (2006) 1.46
Identification of patients with diabetes from the text of physician notes in the electronic medical record. Diabetes Care (2005) 1.44
Hypothesis: exertional heat stroke-induced myopathy and genetically inherited malignant hyperthermia represent the same disorder, the human stress syndrome. Cell Biochem Biophys (2014) 1.44
Structural, optical, and electrical properties of PbSe nanocrystal solids treated thermally or with simple amines. J Am Chem Soc (2008) 1.43
Linking gene expression data with patient survival times using partial least squares. Bioinformatics (2002) 1.42
Identification of a transcriptional profile associated with in vitro invasion in non-small cell lung cancer cell lines. Cancer Biol Ther (2004) 1.42
Regulation of myogenic progenitor proliferation in human fetal skeletal muscle by BMP4 and its antagonist Gremlin. J Cell Biol (2006) 1.42
QT interval and antidepressant use: a cross sectional study of electronic health records. BMJ (2013) 1.40
An epidemiological network model for disease outbreak detection. PLoS Med (2007) 1.31
A SNP-centric database for the investigation of the human genome. BMC Bioinformatics (2004) 1.31
A glimpse of the next 100 years in medicine. N Engl J Med (2012) 1.30
Expression profiling reveals altered satellite cell numbers and glycolytic enzyme transcription in nemaline myopathy muscle. Proc Natl Acad Sci U S A (2003) 1.29
Report of the National Heart, Lung, and Blood Institute Working Group on epigenetics and hypertension. Hypertension (2012) 1.28
A gene expression profile of stem cell pluripotentiality and differentiation is conserved across diverse solid and hematopoietic cancers. Genome Biol (2012) 1.23
Gene expression profile after cardiopulmonary bypass and cardioplegic arrest. J Thorac Cardiovasc Surg (2003) 1.23
Predicting survival within the lung cancer histopathological hierarchy using a multi-scale genomic model of development. PLoS Med (2006) 1.21
Serum proteome profiling detects myelodysplastic syndromes and identifies CXC chemokine ligands 4 and 7 as markers for advanced disease. Proc Natl Acad Sci U S A (2007) 1.20
Interaction of sleep quality and psychosocial stress on obesity in African Americans: the Cardiovascular Health Epidemiology Study (CHES). BMC Public Health (2010) 1.19
Gene expression profiling of Duchenne muscular dystrophy skeletal muscle. Neurogenetics (2003) 1.18
Relation of endothelial nitric oxide synthase gene to plasma nitric oxide level, endothelial function, and blood pressure in African Americans. Am J Hypertens (2004) 1.17
Mechanical stretch is a highly selective regulator of gene expression in human bladder smooth muscle cells. Physiol Genomics (2004) 1.17
Automated validation of genetic variants from large databases: ensuring that variant references refer to the same genomic locations. Bioinformatics (2011) 1.17
Tissue and process specific microRNA-mRNA co-expression in mammalian development and malignancy. PLoS One (2009) 1.17
DITTO - a tool for identification of patient cohorts from the text of physician notes in the electronic medical record. AMIA Annu Symp Proc (2005) 1.15
Bayesian approaches to reverse engineer cellular systems: a simulation study on nonlinear Gaussian networks. BMC Bioinformatics (2007) 1.14
Newborn screening program practices in the United States: notification, research, and consent. Pediatrics (2002) 1.14
Genome-wide association for smoking cessation success in a trial of precessation nicotine replacement. Mol Med (2010) 1.14
Availability and quality of paraffin blocks identified in pathology archives: a multi-institutional study by the Shared Pathology Informatics Network (SPIN). BMC Cancer (2007) 1.14