Published in Science on December 20, 2002
A haplotype map of the human genome. Nature (2005) 105.70
Global variation in copy number in the human genome. Nature (2006) 57.50
Inference of population structure using multilocus genotype data: linked loci and correlated allele frequencies. Genetics (2003) 53.11
Genome-wide detection and characterization of positive selection in human populations. Nature (2007) 17.27
Genetic signatures of strong recent positive selection at the lactase gene. Am J Hum Genet (2004) 11.90
Inferring weak population structure with the assistance of sample group information. Mol Ecol Resour (2009) 10.81
The genetic structure and history of Africans and African Americans. Science (2009) 10.65
Support from the relationship of genetic and geographic distance in human populations for a serial founder effect originating in Africa. Proc Natl Acad Sci U S A (2005) 10.22
The pattern of polymorphism in Arabidopsis thaliana. PLoS Biol (2005) 10.13
Inference of population structure using multilocus genotype data: dominant markers and null alleles. Mol Ecol Notes (2007) 10.11
Variable host-pathogen compatibility in Mycobacterium tuberculosis. Proc Natl Acad Sci U S A (2006) 8.90
Signals of recent positive selection in a worldwide sample of human populations. Genome Res (2009) 8.38
Multiple rare variants in NPC1L1 associated with reduced sterol absorption and plasma low-density lipoprotein levels. Proc Natl Acad Sci U S A (2006) 8.20
New approaches to population stratification in genome-wide association studies. Nat Rev Genet (2010) 7.97
Discriminant analysis of principal components: a new method for the analysis of genetically structured populations. BMC Genet (2010) 7.67
Informativeness of genetic markers for inference of ancestry. Am J Hum Genet (2003) 6.90
Clines, clusters, and the effect of study design on the inference of human population structure. PLoS Genet (2005) 6.73
Variants in nicotinic receptors and risk for nicotine dependence. Am J Psychiatry (2008) 6.73
Association of FKBP5 polymorphisms and childhood abuse with risk of posttraumatic stress disorder symptoms in adults. JAMA (2008) 6.60
African genetic diversity: implications for human demographic history, modern human origins, and complex disease mapping. Annu Rev Genomics Hum Genet (2008) 6.06
Reconstructing genetic ancestry blocks in admixed individuals. Am J Hum Genet (2006) 5.92
Building the sequence map of the human pan-genome. Nat Biotechnol (2009) 5.53
European population substructure: clustering of northern and southern populations. PLoS Genet (2006) 5.27
Genetics in geographically structured populations: defining, estimating and interpreting F(ST). Nat Rev Genet (2009) 5.23
Interrogating multiple aspects of variation in a full resequencing data set to infer human population size changes. Proc Natl Acad Sci U S A (2005) 5.21
Features of evolution and expansion of modern humans, inferred from genomewide microsatellite markers. Am J Hum Genet (2003) 5.14
Integrating ethics and science in the International HapMap Project. Nat Rev Genet (2004) 5.13
Stable association between strains of Mycobacterium tuberculosis and their human host populations. Proc Natl Acad Sci U S A (2004) 4.98
Genetic variation and population structure in native Americans. PLoS Genet (2007) 4.87
Inference of population structure using dense haplotype data. PLoS Genet (2012) 4.87
Inference of population splits and mixtures from genome-wide allele frequency data. PLoS Genet (2012) 4.85
The Population Reference Sample, POPRES: a resource for population, disease, and pharmacological genetics research. Am J Hum Genet (2008) 4.79
Geography predicts neutral genetic diversity of human populations. Curr Biol (2005) 4.74
Human population genetic structure and inference of group membership. Am J Hum Genet (2003) 4.73
Evidence for gradients of human genetic diversity within and among continents. Genome Res (2004) 4.70
Genome-wide association studies in diverse populations. Nat Rev Genet (2010) 4.68
Influence of child abuse on adult depression: moderation by the corticotropin-releasing hormone receptor gene. Arch Gen Psychiatry (2008) 4.65
Ancestry informative marker sets for determining continental origin and admixture proportions in common populations in America. Hum Mutat (2009) 4.65
Statistical tests for admixture mapping with case-control and cases-only data. Am J Hum Genet (2004) 4.52
Genetic structure, self-identified race/ethnicity, and confounding in case-control association studies. Am J Hum Genet (2004) 4.51
The effective mutation rate at Y chromosome short tandem repeats, with application to human population-divergence time. Am J Hum Genet (2003) 4.34
A Markov chain Monte Carlo approach for joint inference of population structure and inbreeding rates from multilocus genotype data. Genetics (2007) 4.31
Enhanced Bayesian modelling in BAPS software for learning genetic structures of populations. BMC Bioinformatics (2008) 4.25
The 1001 genomes project for Arabidopsis thaliana. Genome Biol (2009) 4.10
Bayesian clustering using hidden Markov random fields in spatial population genetics. Genetics (2006) 3.89
Gene-expression variation within and among human populations. Am J Hum Genet (2007) 3.84
A geographically explicit genetic model of worldwide human-settlement history. Am J Hum Genet (2006) 3.81
Progress and promise of genome-wide association studies for human complex trait genetics. Genetics (2010) 3.81
Large-scale SNP analysis reveals clustered and continuous patterns of human genetic variation. Hum Genomics (2005) 3.77
Genetic essentialism: on the deceptive determinism of DNA. Psychol Bull (2011) 3.62
Bayesian species delimitation using multilocus sequence data. Proc Natl Acad Sci U S A (2010) 3.56
The genomic distribution of population substructure in four populations using 8,525 autosomal SNPs. Hum Genomics (2004) 3.53
Evolutionary toggling of the MAPT 17q21.31 inversion region. Nat Genet (2008) 3.42
Inference of population structure under a Dirichlet process model. Genetics (2007) 3.42
The role of geography in human adaptation. PLoS Genet (2009) 3.41
Adipose tissue in muscle: a novel depot similar in size to visceral adipose tissue. Am J Clin Nutr (2005) 3.40
Accounting for ancestry: population substructure and genome-wide association studies. Hum Mol Genet (2008) 3.39
CYP3A variation and the evolution of salt-sensitivity variants. Am J Hum Genet (2004) 3.32
The genetic structure of Pacific Islanders. PLoS Genet (2008) 3.31
Genetic ancestry in lung-function predictions. N Engl J Med (2010) 3.30
Genomewide screening reveals high levels of insertional polymorphism in the human endogenous retrovirus family HERV-K(HML2): implications for present-day activity. J Virol (2005) 3.26
Genomics and the future of conservation genetics. Nat Rev Genet (2010) 3.23
Colloquium paper: genome-wide patterns of population structure and admixture among Hispanic/Latino populations. Proc Natl Acad Sci U S A (2010) 3.20
Addictions biology: haplotype-based analysis for 130 candidate genes on a single array. Alcohol Alcohol (2008) 3.13
Origin, spread and demography of the Mycobacterium tuberculosis complex. PLoS Pathog (2008) 3.10
A genetic atlas of human admixture history. Science (2014) 3.09
ADZE: a rarefaction approach for counting alleles private to combinations of populations. Bioinformatics (2008) 3.06
Genomic dissection of population substructure of Han Chinese and its implication in association studies. Am J Hum Genet (2009) 2.93
Population stratification of a common APOBEC gene deletion polymorphism. PLoS Genet (2007) 2.85
Distinguishing human ethnic groups by means of sequences from Helicobacter pylori: lessons from Ladakh. Proc Natl Acad Sci U S A (2004) 2.83
The history of African gene flow into Southern Europeans, Levantines, and Jews. PLoS Genet (2011) 2.81
Adaptations to climate in candidate genes for common metabolic disorders. PLoS Genet (2008) 2.68
Inferring human colonization history using a copying model. PLoS Genet (2008) 2.64
Mixed-membership models of scientific publications. Proc Natl Acad Sci U S A (2004) 2.63
A genome-wide survey of the prevalence and evolutionary forces acting on human nonsense SNPs. Am J Hum Genet (2009) 2.62
The African Descent and Glaucoma Evaluation Study (ADAGES): design and baseline data. Arch Ophthalmol (2009) 2.59
Adaptive evolution of UGT2B17 copy-number variation. Am J Hum Genet (2008) 2.58
Genomic signatures of positive selection in humans and the limits of outlier approaches. Genome Res (2006) 2.56
Clumpak: a program for identifying clustering modes and packaging population structure inferences across K. Mol Ecol Resour (2015) 2.56
Whole genome expression and biochemical correlates of extreme constitutional types defined in Ayurveda. J Transl Med (2008) 2.55
Abraham's children in the genome era: major Jewish diaspora populations comprise distinct genetic clusters with shared Middle Eastern Ancestry. Am J Hum Genet (2010) 2.54
Using environmental correlations to identify loci underlying local adaptation. Genetics (2010) 2.52
Inferring admixture histories of human populations using linkage disequilibrium. Genetics (2013) 2.51
Evolution in health and medicine Sackler colloquium: Consanguinity, human evolution, and complex diseases. Proc Natl Acad Sci U S A (2009) 2.47
Complex systems thinking and current impasses in health disparities research. Am J Public Health (2011) 2.42
Ancient and recent positive selection transformed opioid cis-regulation in humans. PLoS Biol (2005) 2.37
PCA-correlated SNPs for structure identification in worldwide human populations. PLoS Genet (2007) 2.36
Differential susceptibility to hypertension is due to selection during the out-of-Africa expansion. PLoS Genet (2005) 2.33
Phylogenetic dependency networks: inferring patterns of CTL escape and codon covariation in HIV-1 Gag. PLoS Comput Biol (2008) 2.32
A genome-wide perspective on the evolutionary history of enigmatic wolf-like canids. Genome Res (2011) 2.28
Biases and reconciliation in estimates of linkage disequilibrium in the human genome. Am J Hum Genet (2006) 2.26
Low levels of genetic divergence across geographically and linguistically diverse populations from India. PLoS Genet (2006) 2.26
Robustness of the inference of human population structure: a comparison of X-chromosomal and autosomal microsatellites. Hum Genomics (2004) 2.22
Genomic runs of homozygosity record population history and consanguinity. PLoS One (2010) 2.22
Geography is a better determinant of human genetic differentiation than ethnicity. Hum Genet (2005) 2.20
Spatial patterns of variation due to natural selection in humans. Nat Rev Genet (2009) 2.18
Adaptations to climate-mediated selective pressures in humans. PLoS Genet (2011) 2.15
fastSTRUCTURE: variational inference of population structure in large SNP data sets. Genetics (2014) 2.13
Origins and evolution of the Europeans' genome: evidence from multiple microsatellite loci. Proc Biol Sci (2006) 2.09
Inference of population structure using multilocus genotype data: linked loci and correlated allele frequencies. Genetics (2003) 53.11
A map of recent positive selection in the human genome. PLoS Biol (2006) 29.19
Worldwide human relationships inferred from genome-wide patterns of variation. Science (2008) 22.44
A high-resolution survey of deletion polymorphism in the human genome. Nat Genet (2005) 16.99
Understanding mechanisms underlying human gene expression variation with RNA sequencing. Nature (2010) 16.86
A human genome diversity cell line panel. Science (2002) 14.11
Genotype, haplotype and copy-number variation in worldwide human populations. Nature (2008) 12.40
A systematic survey of loss-of-function variants in human protein-coding genes. Science (2012) 12.25
Traces of human migrations in Helicobacter pylori populations. Science (2003) 11.92
Inferring weak population structure with the assistance of sample group information. Mol Ecol Resour (2009) 10.81
The genetic structure and history of Africans and African Americans. Science (2009) 10.65
Support from the relationship of genetic and geographic distance in human populations for a serial founder effect originating in Africa. Proc Natl Acad Sci U S A (2005) 10.22
Inference of population structure using multilocus genotype data: dominant markers and null alleles. Mol Ecol Notes (2007) 10.11
High-resolution mapping of expression-QTLs yields insight into human gene regulation. PLoS Genet (2008) 9.68
Convergent adaptation of human lactase persistence in Africa and Europe. Nat Genet (2006) 9.44
Local dispersal promotes biodiversity in a real-life game of rock-paper-scissors. Nature (2002) 9.07
A worldwide survey of haplotype variation and linkage disequilibrium in the human genome. Nat Genet (2006) 8.46
Signals of recent positive selection in a worldwide sample of human populations. Genome Res (2009) 8.38
Sequencing and analysis of Neanderthal genomic DNA. Science (2006) 8.06
Evolutionary rate in the protein interaction network. Science (2002) 7.75
The application of molecular genetic approaches to the study of human evolution. Nat Genet (2003) 7.44
Truncated product method for combining P-values. Genet Epidemiol (2002) 7.07
Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma. Nat Genet (2012) 7.00
Overcoming the winner's curse: estimating penetrance parameters from case-control data. Am J Hum Genet (2007) 6.99
Informativeness of genetic markers for inference of ancestry. Am J Hum Genet (2003) 6.90
Clines, clusters, and the effect of study design on the inference of human population structure. PLoS Genet (2005) 6.73
DNA methylation patterns associate with genetic and gene expression variation in HapMap cell lines. Genome Biol (2011) 6.48
DNase I sensitivity QTLs are a major determinant of human expression variation. Nature (2012) 6.17
Revealing the architecture of gene regulation: the promise of eQTL studies. Trends Genet (2008) 5.78
Effect of read-mapping biases on detecting allele-specific expression from RNA-sequencing data. Bioinformatics (2009) 5.62
Accurate inference of transcription factor binding from DNA sequence and chromatin accessibility data. Genome Res (2010) 5.40
A 3.9-centimorgan-resolution human single-nucleotide polymorphism linkage map and screening set. Am J Hum Genet (2003) 5.34
Coalescent-based association mapping and fine mapping of complex trait loci. Genetics (2004) 5.26
Haplotype blocks and linkage disequilibrium in the human genome. Nat Rev Genet (2003) 5.16
Features of evolution and expansion of modern humans, inferred from genomewide microsatellite markers. Am J Hum Genet (2003) 5.14
A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk. Cancer Res (2008) 5.05
High-resolution mapping of crossovers reveals extensive variation in fine-scale recombination patterns among humans. Science (2008) 5.02
Stable association between strains of Mycobacterium tuberculosis and their human host populations. Proc Natl Acad Sci U S A (2004) 4.98
Genetic variation and population structure in native Americans. PLoS Genet (2007) 4.87
Inference of population splits and mixtures from genome-wide allele frequency data. PLoS Genet (2012) 4.85
High functional diversity in Mycobacterium tuberculosis driven by genetic drift and human demography. PLoS Biol (2008) 4.74
Statistical tests for admixture mapping with case-control and cases-only data. Am J Hum Genet (2004) 4.52
Completing the map of human genetic variation. Nature (2007) 4.38
The effective mutation rate at Y chromosome short tandem repeats, with application to human population-divergence time. Am J Hum Genet (2003) 4.34
A high-resolution human contact network for infectious disease transmission. Proc Natl Acad Sci U S A (2010) 4.34
An exact nonparametric method for inferring mosaic structure in sequence triplets. Genetics (2007) 3.76
Confounding from cryptic relatedness in case-control association studies. PLoS Genet (2005) 3.61
Clonal origin and evolution of a transmissible cancer. Cell (2006) 3.60
Hunter-gatherer genomic diversity suggests a southern African origin for modern humans. Proc Natl Acad Sci U S A (2011) 3.53
The role of geography in human adaptation. PLoS Genet (2009) 3.41
Polarity and temporality of high-resolution y-chromosome distributions in India identify both indigenous and exogenous expansions and reveal minor genetic influence of Central Asian pastoralists. Am J Hum Genet (2005) 3.37
Implications of biogeography of human populations for 'race' and medicine. Nat Genet (2004) 3.34
The genetic structure of Pacific Islanders. PLoS Genet (2008) 3.31
Origin, diffusion, and differentiation of Y-chromosome haplogroups E and J: inferences on the neolithization of Europe and later migratory events in the Mediterranean area. Am J Hum Genet (2004) 3.28
Noisy splicing drives mRNA isoform diversity in human cells. PLoS Genet (2010) 3.19
Identification of genetic variants that affect histone modifications in human cells. Science (2013) 3.11
Functional genomic analysis of the rates of protein evolution. Proc Natl Acad Sci U S A (2005) 3.04
Melanesian and Asian origins of Polynesians: mtDNA and Y chromosome gradients across the Pacific. Mol Biol Evol (2006) 2.98
Comment on "Widespread RNA and DNA sequence differences in the human transcriptome". Science (2012) 2.79
Intelligence, race, and genetics. Am Psychol (2005) 2.76
Adaptations to climate in candidate genes for common metabolic disorders. PLoS Genet (2008) 2.68
ALFRED: An allele frequency database for anthropology. Am J Phys Anthropol (2002) 2.67
Genomics: ENCODE explained. Nature (2012) 2.62
A global perspective on genetic variation at the ADH genes reveals unusual patterns of linkage disequilibrium and diversity. Am J Hum Genet (2002) 2.60
Assessing the performance of the haplotype block model of linkage disequilibrium. Am J Hum Genet (2003) 2.59
Using environmental correlations to identify loci underlying local adaptation. Genetics (2010) 2.52
Dissecting the regulatory architecture of gene expression QTLs. Genome Biol (2012) 2.51
Evidence of positive selection acting at the human dopamine receptor D4 gene locus. Proc Natl Acad Sci U S A (2001) 2.48
Ranks of genuine associations in whole-genome scans. Genetics (2005) 2.42
Global diversity and evidence for coevolution of KIR and HLA. Nat Genet (2007) 2.40
Evolutionary dynamics of human Toll-like receptors and their different contributions to host defense. PLoS Genet (2009) 2.35
Phylogeography of Y-chromosome haplogroup I reveals distinct domains of prehistoric gene flow in europe. Am J Hum Genet (2004) 2.32
Genomic patterns of homozygosity in worldwide human populations. Am J Hum Genet (2012) 2.30
Ethnic-difference markers for use in mapping by admixture linkage disequilibrium. Am J Hum Genet (2002) 2.29
Low levels of genetic divergence across geographically and linguistically diverse populations from India. PLoS Genet (2006) 2.26
Bitter receptor gene (TAS2R38), 6-n-propylthiouracil (PROP) bitterness and alcohol intake. Alcohol Clin Exp Res (2004) 2.26
Large-scale reconstruction and phylogenetic analysis of metabolic environments. Proc Natl Acad Sci U S A (2008) 2.23
Robustness of the inference of human population structure: a comparison of X-chromosomal and autosomal microsatellites. Hum Genomics (2004) 2.22
DNA sequence-dependent compartmentalization and silencing of chromatin at the nuclear lamina. Cell (2012) 2.20
Primate transcript and protein expression levels evolve under compensatory selection pressures. Science (2013) 2.18
Low nucleotide diversity in chimpanzees and bonobos. Genetics (2003) 2.16
Adaptations to climate-mediated selective pressures in humans. PLoS Genet (2011) 2.15
Controls of nucleosome positioning in the human genome. PLoS Genet (2012) 2.14
Vibratory Urticaria Associated with a Missense Variant in ADGRE2. N Engl J Med (2016) 2.09
Inferring the demographic history of African farmers and pygmy hunter-gatherers using a multilocus resequencing data set. PLoS Genet (2009) 2.07
Biodiversity of 52 chicken populations assessed by microsatellite typing of DNA pools. Genet Sel Evol (2003) 2.02
Maternal traces of deep common ancestry and asymmetric gene flow between Pygmy hunter-gatherers and Bantu-speaking farmers. Proc Natl Acad Sci U S A (2008) 1.96
Effects of traditional and western environments on prevalence of type 2 diabetes in Pima Indians in Mexico and the U.S. Diabetes Care (2006) 1.96
A genome-wide study of DNA methylation patterns and gene expression levels in multiple human and chimpanzee tissues. PLoS Genet (2011) 1.92
A 360-kb interchromosomal duplication of the human HYDIN locus. Genomics (2006) 1.91
The great human expansion. Proc Natl Acad Sci U S A (2012) 1.86