PubRank

John D Lambris

Author PubWeight™ 297.16‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Complement: a key system for immune surveillance and homeostasis. Nat Immunol 2010 10.37
2 The classical complement cascade mediates CNS synapse elimination. Cell 2007 9.06
3 Generation of C5a in the absence of C3: a new complement activation pathway. Nat Med 2006 5.26
4 Low-abundance biofilm species orchestrates inflammatory periodontal disease through the commensal microbiota and complement. Cell Host Microbe 2011 5.06
5 Modulation of the antitumor immune response by complement. Nat Immunol 2008 4.53
6 Membranoproliferative glomerulonephritis type II (dense deposit disease): an update. J Am Soc Nephrol 2005 3.57
7 Drusen complement components C3a and C5a promote choroidal neovascularization. Proc Natl Acad Sci U S A 2006 3.25
8 Complement-targeted therapeutics. Nat Biotechnol 2007 3.24
9 Structure of C3b reveals conformational changes that underlie complement activity. Nature 2006 3.22
10 The role of complement in inflammatory diseases from behind the scenes into the spotlight. Am J Pathol 2007 3.12
11 New approaches to the treatment of dense deposit disease. J Am Soc Nephrol 2007 3.02
12 Prominent neurodegeneration and increased plaque formation in complement-inhibited Alzheimer's mice. Proc Natl Acad Sci U S A 2002 2.76
13 Regulation of Toll-like receptor-mediated inflammatory response by complement in vivo. Blood 2007 2.72
14 Essential role of the C5a receptor in E coli-induced oxidative burst and phagocytosis revealed by a novel lepirudin-based human whole blood model of inflammation. Blood 2002 2.62
15 Structure of complement fragment C3b-factor H and implications for host protection by complement regulators. Nat Immunol 2009 2.54
16 Complement and coagulation: strangers or partners in crime? Trends Immunol 2007 2.48
17 Complement C5a receptors and neutrophils mediate fetal injury in the antiphospholipid syndrome. J Clin Invest 2003 2.39
18 The proinflammatory mediators C3a and C5a are essential for liver regeneration. J Exp Med 2003 2.38
19 A high-fat diet impairs liver regeneration in C57BL/6 mice through overexpression of the NF-kappaB inhibitor, IkappaBalpha. Hepatology 2005 2.18
20 A regulatory role for the C5a anaphylatoxin in type 2 immunity in asthma. J Clin Invest 2006 2.15
21 A novel C5a receptor-tissue factor cross-talk in neutrophils links innate immunity to coagulation pathways. J Immunol 2006 2.13
22 Molecular intercommunication between the complement and coagulation systems. J Immunol 2010 2.12
23 Complement in immune and inflammatory disorders: pathophysiological mechanisms. J Immunol 2013 2.10
24 The complement inhibitory protein DAF (CD55) suppresses T cell immunity in vivo. J Exp Med 2005 2.09
25 Complement-mediated inhibition of neovascularization reveals a point of convergence between innate immunity and angiogenesis. Blood 2010 2.08
26 Microbial manipulation of receptor crosstalk in innate immunity. Nat Rev Immunol 2011 2.01
27 Protective effects of IL-6 blockade in sepsis are linked to reduced C5a receptor expression. J Immunol 2003 2.00
28 Structural and functional implications of the alternative complement pathway C3 convertase stabilized by a staphylococcal inhibitor. Nat Immunol 2009 1.98
29 A structural basis for complement inhibition by Staphylococcus aureus. Nat Immunol 2007 1.95
30 Microbial hijacking of complement-toll-like receptor crosstalk. Sci Signal 2010 1.91
31 Platelets contribute to the pathogenesis of experimental autoimmune encephalomyelitis. Circ Res 2012 1.85
32 Crosstalk pathways between Toll-like receptors and the complement system. Trends Immunol 2010 1.83
33 Increased C5a receptor expression in sepsis. J Clin Invest 2002 1.79
34 Hydrophobic effect and hydrogen bonds account for the improved activity of a complement inhibitor, compstatin. J Med Chem 2006 1.72
35 Structure of compstatin in complex with complement component C3c reveals a new mechanism of complement inhibition. J Biol Chem 2007 1.71
36 Functional receptor for C3a anaphylatoxin is expressed by normal hematopoietic stem/progenitor cells, and C3a enhances their homing-related responses to SDF-1. Blood 2003 1.68
37 The role of complement in biomaterial-induced inflammation. Mol Immunol 2006 1.67
38 Compstatin: a complement inhibitor on its way to clinical application. Adv Exp Med Biol 2008 1.66
39 Interaction between the coagulation and complement system. Adv Exp Med Biol 2008 1.65
40 The C5a receptor impairs IL-12-dependent clearance of Porphyromonas gingivalis and is required for induction of periodontal bone loss. J Immunol 2010 1.64
41 Complement in immune and inflammatory disorders: therapeutic interventions. J Immunol 2013 1.64
42 Structures of C3b in complex with factors B and D give insight into complement convertase formation. Science 2010 1.59
43 Antibodies against the extracellular enveloped virus B5R protein are mainly responsible for the EEV neutralizing capacity of vaccinia immune globulin. Virology 2004 1.58
44 Complement inhibition decreases the procoagulant response and confers organ protection in a baboon model of Escherichia coli sepsis. Blood 2010 1.56
45 Complement component 3 is required for optimal expansion of CD8 T cells during a systemic viral infection. J Immunol 2003 1.56
46 Peptide inhibitors of C3 activation as a novel strategy of complement inhibition for the treatment of paroxysmal nocturnal hemoglobinuria. Blood 2014 1.55
47 Complement fragment C3a controls mutual cell attraction during collective cell migration. Dev Cell 2011 1.54
48 Human genetic deficiencies reveal the roles of complement in the inflammatory network: lessons from nature. Proc Natl Acad Sci U S A 2009 1.53
49 Expression and function of C5a receptor in mouse microvascular endothelial cells. J Immunol 2002 1.53
50 Diet-induced hepatocellular carcinoma in genetically predisposed mice. Hum Mol Genet 2009 1.52
51 Role of membrane cofactor protein (CD46) in regulation of C4b and C3b deposited on cells. J Immunol 2002 1.51
52 C3a and C3b activation products of the third component of complement (C3) are critical for normal liver recovery after toxic injury. J Immunol 2004 1.48
53 Ceruloplasmin/hephaestin knockout mice model morphologic and molecular features of AMD. Invest Ophthalmol Vis Sci 2008 1.47
54 Interactions between coagulation and complement--their role in inflammation. Semin Immunopathol 2011 1.46
55 C3a is required for the production of CXC chemokines by tubular epithelial cells after renal ishemia/reperfusion. J Immunol 2007 1.45
56 Protection of innate immunity by C5aR antagonist in septic mice. FASEB J 2002 1.44
57 Complement anaphylatoxin C5a contributes to hemodialysis-associated thrombosis. Blood 2010 1.44
58 Complement in inflammatory tissue damage and disease. Trends Immunol 2002 1.43
59 New analogs of the clinical complement inhibitor compstatin with subnanomolar affinity and enhanced pharmacokinetic properties. Immunobiology 2012 1.39
60 Allosteric inhibition of complement function by a staphylococcal immune evasion protein. Proc Natl Acad Sci U S A 2010 1.37
61 Complement C5a receptor is essential for the optimal generation of antiviral CD8+ T cell responses. J Immunol 2004 1.36
62 Local complement-targeted intervention in periodontitis: proof-of-concept using a C5a receptor (CD88) antagonist. J Immunol 2012 1.35
63 Is complement good or bad for cancer patients? A new perspective on an old dilemma. Trends Immunol 2009 1.33
64 Characterization of Ehp, a secreted complement inhibitory protein from Staphylococcus aureus. J Biol Chem 2007 1.32
65 Novel monoclonal antibodies against mouse C3 interfering with complement activation: description of fine specificity and applications to various immunoassays. Mol Immunol 2004 1.32
66 Anaphylatoxin C5a creates a favorable microenvironment for lung cancer progression. J Immunol 2012 1.30
67 Complement C3 and C5 play critical roles in traumatic brain cryoinjury: blocking effects on neutrophil extravasation by C5a receptor antagonist. J Neuroimmunol 2004 1.29
68 Complement: more than a 'guard' against invading pathogens? Trends Immunol 2002 1.28
69 Can cells and biomaterials in therapeutic medicine be shielded from innate immune recognition? Trends Immunol 2010 1.28
70 Design and NMR characterization of active analogues of compstatin containing non-natural amino acids. J Med Chem 2005 1.28
71 Integrated computational and experimental approach for lead optimization and design of compstatin variants with improved activity. J Am Chem Soc 2003 1.28
72 Complexity of complement activation in sepsis. J Cell Mol Med 2008 1.26
73 Binding of C3 fragments on top of adsorbed plasma proteins during complement activation on a model biomaterial surface. Biomaterials 2005 1.25
74 Recent developments in low molecular weight complement inhibitors. Mol Immunol 2009 1.23
75 Complement C3a and C5a modulate osteoclast formation and inflammatory response of osteoblasts in synergism with IL-1β. J Cell Biochem 2011 1.21
76 Do cryopreserved mesenchymal stromal cells display impaired immunomodulatory and therapeutic properties? Stem Cells 2014 1.21
77 Complement inhibition in cancer therapy. Semin Immunol 2013 1.20
78 Synthetic small-molecule complement inhibitors. Curr Opin Investig Drugs 2004 1.20
79 Progress and Trends in Complement Therapeutics. Adv Exp Med Biol 2013 1.20
80 Kinetic analysis of glycoprotein C of herpes simplex virus types 1 and 2 binding to heparin, heparan sulfate, and complement component C3b. Virology 2002 1.19
81 Herpes simplex virus type 1 evades the effects of antibody and complement in vivo. J Virol 2002 1.19
82 Novel analogues of the therapeutic complement inhibitor compstatin with significantly improved affinity and potency. Mol Immunol 2010 1.18
83 Complement modulates the cutaneous microbiome and inflammatory milieu. Proc Natl Acad Sci U S A 2013 1.17
84 C5a promotes development of experimental lupus nephritis which can be blocked with a specific receptor antagonist. Eur J Immunol 2005 1.16
85 A molecular insight into complement evasion by the staphylococcal complement inhibitor protein family. J Immunol 2009 1.16
86 Complementary Tolls in the periodontium: how periodontal bacteria modify complement and Toll-like receptor responses to prevail in the host. Periodontol 2000 2010 1.15
87 Electrostatic modeling predicts the activities of orthopoxvirus complement control proteins. J Immunol 2005 1.15
88 The regulation of liver cell survival by complement. J Immunol 2009 1.15
89 Cholesterol crystals induce complement-dependent inflammasome activation and cytokine release. J Immunol 2014 1.15
90 The C-terminus of complement factor H is essential for host cell protection. Mol Immunol 2007 1.14
91 Complement-dependent neutrophil recruitment is critical for the development of elastase-induced abdominal aortic aneurysm. Circulation 2009 1.13
92 Expression of complement 3 and complement 5 in newt limb and lens regeneration. J Immunol 2003 1.13
93 C5a and TNF-alpha up-regulate the expression of tissue factor in intra-alveolar neutrophils of patients with the acute respiratory distress syndrome. J Immunol 2008 1.13
94 Compstatin, a peptide inhibitor of complement, exhibits species-specific binding to complement component C3. Mol Immunol 2003 1.12
95 G protein coupled receptor specificity for C3a and compound 48/80-induced degranulation in human mast cells: roles of Mas-related genes MrgX1 and MrgX2. Eur J Pharmacol 2011 1.12
96 Liver inflammation and regeneration: two distinct biological phenomena or parallel pathophysiologic processes? Mol Immunol 2006 1.12
97 Dissecting the instant blood-mediated inflammatory reaction in islet xenotransplantation. Xenotransplantation 2008 1.12
98 Murine visceral leishmaniasis: IgM and polyclonal B-cell activation lead to disease exacerbation. Eur J Immunol 2010 1.11
99 The role of complement in tumor growth. Adv Exp Med Biol 2014 1.11
100 The structural basis of compstatin activity examined by structure-function-based design of peptide analogs and NMR. J Biol Chem 2002 1.10
101 A protective role for the fifth complement component (c5) in allergic airway disease. Am J Respir Crit Care Med 2006 1.09
102 Electrostatic contributions drive the interaction between Staphylococcus aureus protein Efb-C and its complement target C3d. Protein Sci 2008 1.09
103 Compstatin: a C3-targeted complement inhibitor reaching its prime for bedside intervention. Eur J Clin Invest 2015 1.08
104 Complement anaphylatoxin C3a is a potent inducer of embryonic chick retina regeneration. Nat Commun 2013 1.08
105 Cutting edge: members of the Staphylococcus aureus extracellular fibrinogen-binding protein family inhibit the interaction of C3d with complement receptor 2. J Immunol 2008 1.07
106 Rational engineering of a minimized immune inhibitor with unique triple-targeting properties. J Immunol 2013 1.07
107 The complement system in teleosts. Fish Shellfish Immunol 2002 1.06
108 The electrostatic nature of C3d-complement receptor 2 association. J Immunol 2004 1.05
109 Effect of complement inhibition and heparin coating on artificial surface-induced leukocyte and platelet activation. Ann Thorac Surg 2004 1.05
110 Unwelcome complement. Cancer Res 2009 1.04
111 Dysregulation of stathmin, a microtubule-destabilizing protein, and up-regulation of Hsp25, Hsp27, and the antioxidant peroxiredoxin 6 in a mouse model of familial amyotrophic lateral sclerosis. Am J Pathol 2004 1.04
112 C5a causes limited, polymorphonuclear cell-independent, mesenteric ischemia/reperfusion-induced injury. Clin Immunol 2003 1.04
113 Studies of structure-activity relations of complement inhibitor compstatin. J Immunol 2003 1.04
114 Complement activation is critical to airway hyperresponsiveness after acute ozone exposure. Am J Respir Crit Care Med 2003 1.03
115 The anaphylatoxin receptor C5aR is present during fracture healing in rats and mediates osteoblast migration in vitro. J Trauma 2011 1.03
116 Genetic and pharmacologic inhibition of complement impairs endothelial cell function and ablates ovarian cancer neovascularization. Neoplasia 2012 1.02
117 Complement-mediated clearance of erythrocytes: mechanism and delineation of the regulatory roles of Crry and DAF. Decay-accelerating factor. Blood 2002 1.02
118 Innate immunity activation on biomaterial surfaces: a mechanistic model and coping strategies. Adv Drug Deliv Rev 2011 1.01
119 Suppression of drusen formation by compstatin, a peptide inhibitor of complement C3 activation, on cynomolgus monkey with early-onset macular degeneration. Adv Exp Med Biol 2010 1.00
120 Acute antibody-mediated complement activation mediates lysis of pancreatic islets cells and may cause tissue loss in clinical islet transplantation. Transplantation 2008 1.00
121 PMX-53 as a dual CD88 antagonist and an agonist for Mas-related gene 2 (MrgX2) in human mast cells. Mol Pharmacol 2011 1.00
122 Mesenchymal stromal cells engage complement and complement receptor bearing innate effector cells to modulate immune responses. PLoS One 2011 0.99
123 Structure-kinetic relationship analysis of the therapeutic complement inhibitor compstatin. J Mol Recognit 2009 0.99
124 A complement-IL-4 regulatory circuit controls liver regeneration. J Immunol 2011 0.99
125 Complement component C3 binds to activated normal platelets without preceding proteolytic activation and promotes binding to complement receptor 1. J Immunol 2010 0.98
126 Synergistic neuroprotective effects of C3a and C5a receptor blockade following intracerebral hemorrhage. Brain Res 2009 0.97
127 Restoration of complement-enhanced neutralization of vaccinia virus virions by novel monoclonal antibodies raised against the vaccinia virus complement control protein. J Virol 2003 0.97
128 Absence of mannose-binding lectin prevents hyperglycemic cardiovascular complications. Am J Pathol 2011 0.96
129 Diversity in the C3b [corrected] contact residues and tertiary structures of the staphylococcal complement inhibitor (SCIN) protein family. J Biol Chem 2011 0.96
130 Protection of nonself surfaces from complement attack by factor H-binding peptides: implications for therapeutic medicine. J Immunol 2011 0.96
131 C5L2 receptor disruption enhances the development of diet-induced insulin resistance in mice. Immunobiology 2012 0.96
132 Complement component C5a mediates hemorrhage-induced intestinal damage. J Surg Res 2008 0.95
133 The role of the complement system in metabolic organs and metabolic diseases. Semin Immunol 2013 0.95
134 C3 promotes expansion of CD8+ and CD4+ T cells in a Listeria monocytogenes infection. J Immunol 2009 0.95
135 C3a receptor antagonist attenuates brain injury after intracerebral hemorrhage. J Cereb Blood Flow Metab 2008 0.95
136 Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) open reading frame 4 protein (kaposica) is a functional homolog of complement control proteins. J Virol 2003 0.95
137 Complement and dysbiosis in periodontal disease. Immunobiology 2012 0.94
138 Effect of supraphysiologic levels of C1-inhibitor on the classical, lectin and alternative pathways of complement. Mol Immunol 2006 0.94
139 Complement in paroxysmal nocturnal hemoglobinuria: exploiting our current knowledge to improve the treatment landscape. Expert Rev Hematol 2014 0.94
140 Synthesis and activity of thioether-containing analogues of the complement inhibitor compstatin. ACS Chem Biol 2011 0.94
141 Does complement play a role in bone development and regeneration? Immunobiology 2012 0.94
142 Conformational interconversion in compstatin probed with molecular dynamics simulations. Proteins 2003 0.94
143 Stages of meningococcal sepsis simulated in vitro, with emphasis on complement and Toll-like receptor activation. Infect Immun 2008 0.94
144 Partial hepatectomy induced liver proteome changes in mice. Proteomics 2005 0.94
145 Ornithodoros moubata complement inhibitor is an equally effective C5 inhibitor in pigs and humans. J Immunol 2011 0.93
146 Differential effect of heparin coating and complement inhibition on artificial surface-induced eicosanoid production. Ann Thorac Surg 2005 0.93
147 Ancient origin of the complement system: emerging invertebrate models. Adv Exp Med Biol 2007 0.93
148 Complement: structure, functions, evolution, and viral molecular mimicry. Immunol Res 2003 0.93
149 Liver regeneration: a link to inflammation through complement. Adv Exp Med Biol 2006 0.93
150 Targeted complement inhibition as a promising strategy for preventing inflammatory complications in hemodialysis. Immunobiology 2012 0.93
151 Exploring the complement interaction network using surface plasmon resonance. Adv Exp Med Biol 2007 0.93
152 T cell-derived interleukin (IL)-21 promotes brain injury following stroke in mice. J Exp Med 2014 0.93
153 Pathogenic microbes and community service through manipulation of innate immunity. Adv Exp Med Biol 2012 0.92
154 Role of complement in host-microbe homeostasis of the periodontium. Semin Immunol 2013 0.92
155 The complement anaphylatoxin C5a receptor contributes to obese adipose tissue inflammation and insulin resistance. J Immunol 2013 0.92
156 Solvent accessibility of native and hydrolyzed human complement protein 3 analyzed by hydrogen/deuterium exchange and mass spectrometry. J Immunol 2005 0.91
157 DAF/Crry double deficiency in mice exacerbates nephrotoxic serum-induced proteinuria despite markedly reduced systemic complement activity. Mol Immunol 2006 0.90
158 Novel biological networks modulated by complement. Clin Immunol 2005 0.90
159 Inhibition of biomaterial-induced complement activation attenuates the inflammatory host response to implantation. FASEB J 2013 0.89
160 Thermodynamic studies on the interaction of the third complement component and its inhibitor, compstatin. J Biol Chem 2004 0.89
161 C5a receptor-dependent cell activation by physiological concentrations of desarginated C5a: insights from a novel label-free cellular assay. J Immunol 2012 0.89
162 Complement-triggered pathways orchestrate regenerative responses throughout phylogenesis. Semin Immunol 2013 0.89
163 Solution insights into the structure of the Efb/C3 complement inhibitory complex as revealed by lysine acetylation and mass spectrometry. J Am Soc Mass Spectrom 2008 0.89
164 Development of a new pharmacophore model that discriminates active compstatin analogs. Chem Biol Drug Des 2008 0.89
165 C5aR-antagonist significantly reduces the deleterious effect of a blunt chest trauma on fracture healing. J Orthop Res 2011 0.88
166 Conformational analysis of compstatin analogues with molecular dynamics simulations in explicit water. J Mol Graph Model 2007 0.88
167 Expression of compstatin in Escherichia coli: incorporation of unnatural amino acids enhances its activity. Protein Expr Purif 2005 0.88
168 Crystallization of human complement component C3b in the presence of a staphylococcal complement-inhibitor protein (SCIN). Acta Crystallogr Sect F Struct Biol Cryst Commun 2009 0.88
169 Compstatin inhibits complement activation by binding to the beta-chain of complement factor 3. Mol Immunol 2006 0.88
170 Advances in understanding the structure, function, and mechanism of the SCIN and Efb families of Staphylococcal immune evasion proteins. Adv Exp Med Biol 2012 0.88
171 To regeneration...with complement. Adv Exp Med Biol 2006 0.88
172 Molecular basis for complement recognition and inhibition determined by crystallographic studies of the staphylococcal complement inhibitor (SCIN) bound to C3c and C3b. J Mol Biol 2010 0.88
173 A simple, yet highly accurate, QSAR model captures the complement inhibitory activity of compstatin. Bioorg Med Chem 2006 0.88
174 The role of properdin in zymosan- and Escherichia coli-induced complement activation. J Immunol 2012 0.87
175 Complement in urochordates: cloning and characterization of two C3-like genes in the ascidian Ciona intestinalis. Immunogenetics 2002 0.87
176 Dynamic structural changes during complement C3 activation analyzed by hydrogen/deuterium exchange mass spectrometry. Mol Immunol 2008 0.86
177 In vivo significance of ITK-SLP-76 interaction in cytokine production. Mol Cell Biol 2010 0.86
178 Post challenge inhibition of C3 and CD14 attenuates Escherichia coli-induced inflammation in human whole blood. Innate Immun 2013 0.86
179 Immune evasion of Moraxella catarrhalis involves ubiquitous surface protein A-dependent C3d binding. J Immunol 2011 0.86
180 Acute lung injury and fibrosis in a baboon model of Escherichia coli sepsis. Am J Respir Cell Mol Biol 2014 0.85
181 The effects of selective complement and CD14 inhibition on the E. coli-induced tissue factor mRNA upregulation, monocyte tissue factor expression, and tissue factor functional activity in human whole blood. Adv Exp Med Biol 2013 0.85
182 Contribution of chondroitin sulfate A to the binding of complement proteins to activated platelets. PLoS One 2010 0.84
183 Cytokine secretion depends on Galalpha(1,3)Gal expression in a pig-to-human whole blood model. J Immunol 2008 0.84
184 Blood protein-polymer adsorption: implications for understanding complement-mediated hemoincompatibility. J Biomed Mater Res A 2011 0.84
185 CiC3-1a-mediated chemotaxis in the deuterostome invertebrate Ciona intestinalis (Urochordata). J Immunol 2003 0.84
186 Mouse genetics and proteomic analyses demonstrate a critical role for complement in a model of DHRD/ML, an inherited macular degeneration. Hum Mol Genet 2013 0.83
187 Complement-targeted therapeutics in periodontitis. Adv Exp Med Biol 2013 0.83
188 Progress and trends in complement therapeutics. Adv Exp Med Biol 2013 0.83
189 Autoregulation of thromboinflammation on biomaterial surfaces by a multicomponent therapeutic coating. Biomaterials 2012 0.83
190 The induction of cytokines by polycation containing microspheres by a complement dependent mechanism. Biomaterials 2012 0.83
191 Real-time label-free detection of complement activation products in human serum by white light reflectance spectroscopy. Biosens Bioelectron 2009 0.82
192 The role of third complement component (C3) in homing of hematopoietic stem/progenitor cells into bone marrow. Adv Exp Med Biol 2006 0.82
193 Selective inhibition of TNF-alpha or IL-1 beta does not affect E. coli-induced inflammation in human whole blood. Mol Immunol 2010 0.82
194 Hydrogen/deuterium exchange mass spectrometry: potential for investigating innate immunity proteins. Adv Exp Med Biol 2007 0.82
195 A complement receptor C5a antagonist regulates epithelial to mesenchymal transition and crystallin expression after lens cataract surgery in mice. Mol Vis 2011 0.82
196 Complement activation by CpG in a human whole blood loop system: mechanisms and immunomodulatory effects. J Immunol 2009 0.81
197 A structurally dynamic N-terminal helix is a key functional determinant in staphylococcal complement inhibitor (SCIN) proteins. J Biol Chem 2012 0.81
198 Physical methods for structure, dynamics and binding in immunological research. Trends Immunol 2004 0.81
199 Artificial surface-induced inflammation relies on complement factor 5: proof from a deficient person. Ann Thorac Surg 2011 0.80
200 First identification of a chemotactic receptor in an invertebrate species: structural and functional characterization of Ciona intestinalis C3a receptor. J Immunol 2006 0.80
201 Complement and neutrophil function changes after liver resection in humans. World J Surg 2009 0.80
202 Conjugation to albumin-binding molecule tags as a strategy to improve both efficacy and pharmacokinetic properties of the complement inhibitor compstatin. ChemMedChem 2014 0.79
203 A sweet spot to control complement-induced inflammation. Nat Med 2012 0.79
204 Complement Involvement in Periodontitis: Molecular Mechanisms and Rational Therapeutic Approaches. Adv Exp Med Biol 2015 0.79
205 Early post-operative measurement of cytokine plasma levels combined with pre-operative bilirubin levels identify high-risk patients after liver resection. Int J Mol Med 2010 0.79
206 Anti-inflammatory effects of C1-Inhibitor in porcine and human whole blood are independent of its protease inhibition activity. Innate Immun 2009 0.79
207 Neisseria meningitidis and Escherichia coli are protected from leukocyte phagocytosis by binding to erythrocyte complement receptor 1 in human blood. Mol Immunol 2011 0.78
208 ciCD94-1, an ascidian multipurpose C-type lectin-like receptor expressed in Ciona intestinalis hemocytes and larval neural structures. Differentiation 2007 0.78
209 Contact activation of C3 enables tethering between activated platelets and polymorphonuclear leukocytes via CD11b/CD18. Thromb Haemost 2015 0.78
210 Preclinical evaluation of innate immunity to baculovirus gene therapy vectors in whole human blood. Mol Immunol 2009 0.78
211 Immune competence of the Ciona intestinalis pharynx: complement system-mediated activity. Fish Shellfish Immunol 2012 0.78
212 Complement deposits on ocular tissues adjacent to sites of inflammation. Curr Eye Res 2007 0.78
213 Cross-disciplinary research stirs new challenges into the study of the structure, function and systems biology of complement. Adv Exp Med Biol 2006 0.78
214 Regulation of immune responsiveness in vivo by disrupting an early T-cell signaling event using a cell-permeable peptide. PLoS One 2013 0.77
215 Innate immunity mechanisms. Adv Exp Med Biol 2012 0.77
216 Molecular cloning of the beta subunit of complement component eight of rainbow trout. Dev Comp Immunol 2003 0.77
217 A functional C5a anaphylatoxin receptor in a teleost species. J Immunol 2004 0.77
218 Induction of complement C3a receptor responses by kallikrein-related peptidase 14. J Immunol 2013 0.76
219 Regulation of Instant Blood Mediated Inflammatory Reaction (IBMIR) in Pancreatic Islet Xeno-Transplantation: Points for Therapeutic Interventions. Adv Exp Med Biol 2015 0.76
220 CMAP: Complement Map Database. Bioinformatics 2013 0.76
221 Complement in Action: An Analysis of Patent Trends from 1976 Through 2011. Adv Exp Med Biol 2013 0.76
222 Activation of polymorphonuclear leukocytes by candidate biomaterials for an implantable glucose sensor. J Diabetes Sci Technol 2011 0.76
223 Hypoxia and reoxygenation of primary human hepatocytes induce proteome changes of glucose metabolism, oxidative protection and peroxisomal function. Int J Mol Med 2010 0.75
224 Aegean reflections on innate immunity. Nat Immunol 2013 0.75
225 The XXIV International Complement Workshop (ICW) on October 10-15, 2012. Preface. Immunobiology 2012 0.75
226 Illuminating the latest advances in innate immunity on the island of the sun god. Expert Rev Clin Immunol 2010 0.75
227 Mechanisms of action of differentiation inducers: detection of inducer binding protein(s) in murine erythroleukemia cells. Oncol Res 2005 0.75
228 Complement in action: an analysis of patent trends from 1976 through 2011. Adv Exp Med Biol 2013 0.75