| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Mitochondria dysfunction of Alzheimer's disease cybrids enhances Abeta toxicity.
|
J Neurochem
|
2004
|
1.58
|
|
2
|
Ubiquitin proteasome system in Parkinson's disease: a keeper or a witness?
|
Exp Neurol
|
2012
|
1.50
|
|
3
|
Mitochondrial dysfunction and reactive oxygen species in excitotoxicity and apoptosis: implications for the pathogenesis of neurodegenerative diseases.
|
Neurochem Res
|
2003
|
1.34
|
|
4
|
Insulin in central nervous system: more than just a peripheral hormone.
|
J Aging Res
|
2012
|
1.33
|
|
5
|
Cytochrome c oxidase is decreased in Alzheimer's disease platelets.
|
Neurobiol Aging
|
2004
|
1.30
|
|
6
|
Dual presynaptic control by ATP of glutamate release via facilitatory P2X1, P2X2/3, and P2X3 and inhibitory P2Y1, P2Y2, and/or P2Y4 receptors in the rat hippocampus.
|
J Neurosci
|
2005
|
1.29
|
|
7
|
Adenosine A2A receptor blockade prevents synaptotoxicity and memory dysfunction caused by beta-amyloid peptides via p38 mitogen-activated protein kinase pathway.
|
J Neurosci
|
2009
|
1.23
|
|
8
|
Mitochondrial-dependent Ca2+ handling in Huntington's disease striatal cells: effect of histone deacetylase inhibitors.
|
J Neurosci
|
2006
|
1.19
|
|
9
|
Modulator effects of interleukin-1beta and tumor necrosis factor-alpha on AMPA-induced excitotoxicity in mouse organotypic hippocampal slice cultures.
|
J Neurosci
|
2005
|
1.19
|
|
10
|
Lipoic acid and N-acetyl cysteine decrease mitochondrial-related oxidative stress in Alzheimer disease patient fibroblasts.
|
J Alzheimers Dis
|
2007
|
1.19
|
|
11
|
Autophagocytosis of mitochondria is prominent in Alzheimer disease.
|
J Neuropathol Exp Neurol
|
2007
|
1.18
|
|
12
|
An endoplasmic-reticulum-specific apoptotic pathway is involved in prion and amyloid-beta peptides neurotoxicity.
|
Neurobiol Dis
|
2006
|
1.17
|
|
13
|
CXCL12/CXCR4 promotes motility and proliferation of glioma cells.
|
Cancer Biol Ther
|
2010
|
1.17
|
|
14
|
Alzheimer disease and the role of free radicals in the pathogenesis of the disease.
|
CNS Neurol Disord Drug Targets
|
2008
|
1.15
|
|
15
|
Increased autophagic degradation of mitochondria in Alzheimer disease.
|
Autophagy
|
2007
|
1.14
|
|
16
|
Co-localization and functional interaction between adenosine A(2A) and metabotropic group 5 receptors in glutamatergic nerve terminals of the rat striatum.
|
J Neurochem
|
2005
|
1.11
|
|
17
|
Cellular and molecular mechanisms involved in the neurotoxicity of opioid and psychostimulant drugs.
|
Brain Res Rev
|
2008
|
1.11
|
|
18
|
Metformin promotes isolated rat liver mitochondria impairment.
|
Mol Cell Biochem
|
2007
|
1.10
|
|
19
|
The release of calcium from the endoplasmic reticulum induced by amyloid-beta and prion peptides activates the mitochondrial apoptotic pathway.
|
Neurobiol Dis
|
2008
|
1.09
|
|
20
|
An integrative view of the role of oxidative stress, mitochondria and insulin in Alzheimer's disease.
|
J Alzheimers Dis
|
2009
|
1.08
|
|
21
|
Morphological alterations induced by doxorubicin on H9c2 myoblasts: nuclear, mitochondrial, and cytoskeletal targets.
|
Cell Biol Toxicol
|
2008
|
1.08
|
|
22
|
Oxidative stress involvement in alpha-synuclein oligomerization in Parkinson's disease cybrids.
|
Antioxid Redox Signal
|
2009
|
1.08
|
|
23
|
Brain mitochondrial dysfunction as a link between Alzheimer's disease and diabetes.
|
J Neurol Sci
|
2007
|
1.07
|
|
24
|
Mitochondrial function in Parkinson's disease cybrids containing an nt2 neuron-like nuclear background.
|
Mitochondrion
|
2008
|
1.07
|
|
25
|
Mechanisms of action of metformin in type 2 diabetes and associated complications: an overview.
|
Mini Rev Med Chem
|
2008
|
1.07
|
|
26
|
Decrease of adenosine A1 receptor density and of adenosine neuromodulation in the hippocampus of kindled rats.
|
Eur J Neurosci
|
2003
|
1.06
|
|
27
|
Tamoxifen and estradiol interact with the flavin mononucleotide site of complex I leading to mitochondrial failure.
|
J Biol Chem
|
2006
|
1.05
|
|
28
|
Insulin restores metabolic function in cultured cortical neurons subjected to oxidative stress.
|
Diabetes
|
2006
|
1.04
|
|
29
|
Overactivation of calcineurin induced by amyloid-beta and prion proteins.
|
Neurochem Int
|
2008
|
1.04
|
|
30
|
Insulin signaling, glucose metabolism and mitochondria: major players in Alzheimer's disease and diabetes interrelation.
|
Brain Res
|
2012
|
1.04
|
|
31
|
Cholesterol and statins in Alzheimer's disease: current controversies.
|
Exp Neurol
|
2009
|
1.03
|
|
32
|
Alzheimer's disease: a lesson from mitochondrial dysfunction.
|
Antioxid Redox Signal
|
2007
|
1.02
|
|
33
|
Metformin protects the brain against the oxidative imbalance promoted by type 2 diabetes.
|
Med Chem
|
2008
|
1.01
|
|
34
|
Blood oxidative stress markers in non-alcoholic steatohepatitis and how it correlates with diet.
|
Scand J Gastroenterol
|
2008
|
0.99
|
|
35
|
Cytosolic and mitochondrial ROS in staurosporine-induced retinal cell apoptosis.
|
Free Radic Biol Med
|
2003
|
0.99
|
|
36
|
Alzheimer-specific epitopes of tau represent lipid peroxidation-induced conformations.
|
Free Radic Biol Med
|
2005
|
0.98
|
|
37
|
Increased vulnerability of brain mitochondria in diabetic (Goto-Kakizaki) rats with aging and amyloid-beta exposure.
|
Diabetes
|
2003
|
0.98
|
|
38
|
Involvement of endoplasmic reticulum Ca2+ release through ryanodine and inositol 1,4,5-triphosphate receptors in the neurotoxic effects induced by the amyloid-beta peptide.
|
J Neurosci Res
|
2004
|
0.98
|
|
39
|
Induction of cytochrome c-mediated apoptosis by amyloid beta 25-35 requires functional mitochondria.
|
Brain Res
|
2002
|
0.98
|
|
40
|
Blockade of adenosine A(2A) receptors prevents staurosporine-induced apoptosis of rat hippocampal neurons.
|
Neurobiol Dis
|
2007
|
0.97
|
|
41
|
Dysfunctional mitochondria uphold calpain activation: contribution to Parkinson's disease pathology.
|
Neurobiol Dis
|
2009
|
0.97
|
|
42
|
Endoplasmic reticulum and mitochondria interplay mediates apoptotic cell death: relevance to Parkinson's disease.
|
Neurochem Int
|
2009
|
0.96
|
|
43
|
Epigenetics in neurodegeneration: a new layer of complexity.
|
Prog Neuropsychopharmacol Biol Psychiatry
|
2010
|
0.96
|
|
44
|
Subcellular localization of adenosine A(1) receptors in nerve terminals and synapses of the rat hippocampus.
|
Brain Res
|
2003
|
0.96
|
|
45
|
Adenosine A3 receptors are located in neurons of the rat hippocampus.
|
Neuroreport
|
2003
|
0.95
|
|
46
|
FK506 prevents mitochondrial-dependent apoptotic cell death induced by 3-nitropropionic acid in rat primary cortical cultures.
|
Neurobiol Dis
|
2004
|
0.94
|
|
47
|
Neurodegeneration in an Abeta-induced model of Alzheimer's disease: the role of Cdk5.
|
Aging Cell
|
2009
|
0.94
|
|
48
|
Cdk5 acts as a mediator of neuronal cell cycle re-entry triggered by amyloid-beta and prion peptides.
|
Cell Cycle
|
2009
|
0.94
|
|
49
|
Endoplasmic reticulum stress occurs downstream of GluN2B subunit of N-methyl-d-aspartate receptor in mature hippocampal cultures treated with amyloid-β oligomers.
|
Aging Cell
|
2012
|
0.93
|
|
50
|
Lack of evidence for functional TRPV1 vanilloid receptors in rat hippocampal nerve terminals.
|
Neurosci Lett
|
2006
|
0.93
|
|
51
|
Effects of estrogen in the brain: is it a neuroprotective agent in Alzheimer's disease?
|
Curr Aging Sci
|
2010
|
0.93
|
|
52
|
Oxidative stress: the old enemy in Alzheimer's disease pathophysiology.
|
Curr Alzheimer Res
|
2005
|
0.93
|
|
53
|
Role of cyclin-dependent kinase 5 in the neurodegenerative process triggered by amyloid-Beta and prion peptides: implications for Alzheimer's disease and prion-related encephalopathies.
|
Cell Mol Neurobiol
|
2007
|
0.92
|
|
54
|
Long-term effect of convulsive behavior on the density of adenosine A1 and A 2A receptors in the rat cerebral cortex.
|
Epilepsia
|
2005
|
0.92
|
|
55
|
Microtubule depolymerization potentiates alpha-synuclein oligomerization.
|
Front Aging Neurosci
|
2010
|
0.92
|
|
56
|
Insulin is a two-edged knife on the brain.
|
J Alzheimers Dis
|
2009
|
0.92
|
|
57
|
Insulin neuroprotection against oxidative stress is mediated by Akt and GSK-3beta signaling pathways and changes in protein expression.
|
Biochim Biophys Acta
|
2008
|
0.91
|
|
58
|
ER-mediated stress induces mitochondrial-dependent caspases activation in NT2 neuron-like cells.
|
BMB Rep
|
2009
|
0.91
|
|
59
|
Mitochondrial metabolism in Parkinson's disease impairs quality control autophagy by hampering microtubule-dependent traffic.
|
Hum Mol Genet
|
2012
|
0.91
|
|
60
|
Amyloid-β-induced mitochondrial dysfunction impairs the autophagic lysosomal pathway in a tubulin dependent pathway.
|
J Alzheimers Dis
|
2011
|
0.90
|
|
61
|
Metabolic alterations induced by sucrose intake and Alzheimer's disease promote similar brain mitochondrial abnormalities.
|
Diabetes
|
2012
|
0.89
|
|
62
|
Vital imaging of H9c2 myoblasts exposed to tert-butylhydroperoxide--characterization of morphological features of cell death.
|
BMC Cell Biol
|
2007
|
0.89
|
|
63
|
Doxorubicin-induced mitochondrial dysfunction is secondary to nuclear p53 activation in H9c2 cardiomyoblasts.
|
Cancer Chemother Pharmacol
|
2009
|
0.89
|
|
64
|
Involvement of mitochondria in endoplasmic reticulum stress-induced apoptotic cell death pathway triggered by the prion peptide PrP(106-126).
|
J Neurochem
|
2007
|
0.89
|
|
65
|
Adenosine A2A receptor blockade prevents memory dysfunction caused by beta-amyloid peptides but not by scopolamine or MK-801.
|
Exp Neurol
|
2007
|
0.88
|
|
66
|
Modification of adenosine A1 and A2A receptor density in the hippocampus of streptozotocin-induced diabetic rats.
|
Neurochem Int
|
2005
|
0.88
|
|
67
|
Expression and subcellular localization of a novel nuclear acetylcholinesterase protein.
|
J Biol Chem
|
2007
|
0.88
|
|
68
|
Activation of the endoplasmic reticulum stress response by the amyloid-beta 1-40 peptide in brain endothelial cells.
|
Biochim Biophys Acta
|
2013
|
0.88
|
|
69
|
Mitochondria and ubiquitin-proteasomal system interplay: relevance to Parkinson's disease.
|
Free Radic Biol Med
|
2008
|
0.88
|
|
70
|
Evidence of apoptosis and mitochondrial abnormalities in peripheral blood cells of Huntington's disease patients.
|
Biochem Biophys Res Commun
|
2008
|
0.88
|
|
71
|
Mitochondria as a therapeutic target in Alzheimer's disease and diabetes.
|
CNS Neurol Disord Drug Targets
|
2009
|
0.87
|
|
72
|
Caspase-dependent and -independent cell death induced by 3-nitropropionic acid in rat cortical neurons.
|
J Cell Biochem
|
2006
|
0.87
|
|
73
|
Cyanide preconditioning protects brain endothelial and NT2 neuron-like cells against glucotoxicity: role of mitochondrial reactive oxygen species and HIF-1α.
|
Neurobiol Dis
|
2011
|
0.87
|
|
74
|
Comparative study of microglia activation induced by amyloid-beta and prion peptides: role in neurodegeneration.
|
J Neurosci Res
|
2006
|
0.87
|
|
75
|
Mitochondria from distinct tissues are differently affected by 17β-estradiol and tamoxifen.
|
J Steroid Biochem Mol Biol
|
2010
|
0.86
|
|
76
|
Estradiol affects liver mitochondrial function in ovariectomized and tamoxifen-treated ovariectomized female rats.
|
Toxicol Appl Pharmacol
|
2007
|
0.86
|
|
77
|
Up-regulation of neuropeptide Y levels and modulation of glutamate release through neuropeptide Y receptors in the hippocampus of kainate-induced epileptic rats.
|
J Neurochem
|
2005
|
0.85
|
|
78
|
Neurotoxicity of heroin-cocaine combinations in rat cortical neurons.
|
Toxicology
|
2010
|
0.85
|
|
79
|
Amyloid β-induced ER stress is enhanced under mitochondrial dysfunction conditions.
|
Neurobiol Aging
|
2011
|
0.85
|
|
80
|
Bioenergetic dysfunction in Huntington's disease human cybrids.
|
Exp Neurol
|
2011
|
0.84
|
|
81
|
Protein kinase C activity blocks neuropeptide Y-mediated inhibition of glutamate release and contributes to excitability of the hippocampus in status epilepticus.
|
FASEB J
|
2006
|
0.84
|
|
82
|
Type 2 diabetic and Alzheimer's disease mice present similar behavioral, cognitive, and vascular anomalies.
|
J Alzheimers Dis
|
2013
|
0.84
|
|
83
|
Enhanced adenosine A2A receptor facilitation of synaptic transmission in the hippocampus of aged rats.
|
J Neurophysiol
|
2003
|
0.84
|
|
84
|
CoQ10 therapy attenuates amyloid beta-peptide toxicity in brain mitochondria isolated from aged diabetic rats.
|
Exp Neurol
|
2005
|
0.84
|
|
85
|
ER stress-mediated apoptotic pathway induced by Abeta peptide requires the presence of functional mitochondria.
|
J Alzheimers Dis
|
2010
|
0.83
|
|
86
|
Mitochondrial preconditioning: a potential neuroprotective strategy.
|
Front Aging Neurosci
|
2010
|
0.83
|
|
87
|
Insulin neuroprotection against oxidative stress in cortical neurons--involvement of uric acid and glutathione antioxidant defenses.
|
Free Radic Biol Med
|
2005
|
0.83
|
|
88
|
Neuroprotective effect of H. perforatum extracts on beta-amyloid-induced neurotoxicity.
|
Neurotox Res
|
2004
|
0.83
|
|
89
|
Acute effects of cocaine, morphine and their combination on bioenergetic function and susceptibility to oxidative stress of rat liver mitochondria.
|
Life Sci
|
2013
|
0.83
|
|
90
|
Galantamine protects against oxidative stress induced by amyloid-beta peptide in cortical neurons.
|
Eur J Neurosci
|
2009
|
0.83
|
|
91
|
BDNF regulates BIM expression levels in 3-nitropropionic acid-treated cortical neurons.
|
Neurobiol Dis
|
2009
|
0.83
|
|
92
|
Glibenclamide interferes with mitochondrial bioenergetics by inducing changes on membrane ion permeability.
|
J Biochem Mol Toxicol
|
2004
|
0.83
|
|
93
|
Solubilization and immunological identification of presynaptic alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors in the rat hippocampus.
|
Neurosci Lett
|
2003
|
0.82
|
|
94
|
Insulin protects against amyloid beta-peptide toxicity in brain mitochondria of diabetic rats.
|
Neurobiol Dis
|
2005
|
0.82
|
|
95
|
Mitochondria as potential targets in antidiabetic therapy.
|
Handb Exp Pharmacol
|
2011
|
0.82
|
|
96
|
Glutathione redox cycle dysregulation in Huntington's disease knock-in striatal cells.
|
Free Radic Biol Med
|
2012
|
0.82
|
|
97
|
Effect of α-synuclein on amyloid β-induced toxicity: relevance to Lewy body variant of Alzheimer disease.
|
Neurochem Res
|
2013
|
0.82
|
|
98
|
Alzheimer's disease: the quest to understand complexity.
|
J Alzheimers Dis
|
2010
|
0.82
|
|
99
|
Increase of cannabinoid CB1 receptor density in the hippocampus of streptozotocin-induced diabetic rats.
|
Exp Neurol
|
2007
|
0.82
|
|
100
|
Impact of STZ-induced hyperglycemia and insulin-induced hypoglycemia in plasma amino acids and cortical synaptosomal neurotransmitters.
|
Synapse
|
2010
|
0.82
|
|
101
|
Brain mitochondrial injury induced by oxidative stress-related events is prevented by tamoxifen.
|
Neuropharmacology
|
2005
|
0.82
|
|
102
|
Compromised mitochondrial complex II in models of Machado-Joseph disease.
|
Biochim Biophys Acta
|
2011
|
0.82
|
|
103
|
Modification of adenosine modulation of acetylcholine release in the hippocampus of aged rats.
|
Neurobiol Aging
|
2007
|
0.81
|
|
104
|
Dysregulation of CREB activation and histone acetylation in 3-nitropropionic acid-treated cortical neurons: prevention by BDNF and NGF.
|
Neurotox Res
|
2009
|
0.81
|
|
105
|
Bifunctional phenolic-choline conjugates as anti-oxidants and acetylcholinesterase inhibitors.
|
J Enzyme Inhib Med Chem
|
2010
|
0.81
|
|
106
|
N-acyldopamines control striatal input terminals via novel ligand-gated cation channels.
|
Neuropharmacology
|
2008
|
0.81
|
|
107
|
Different roles of adenosine A1, A2A and A3 receptors in controlling kainate-induced toxicity in cortical cultured neurons.
|
Neurochem Int
|
2005
|
0.81
|
|
108
|
Mitochondrial apoptotic cell death and moderate superoxide generation upon selective activation of non-desensitizing AMPA receptors in hippocampal cultures.
|
J Neurochem
|
2003
|
0.81
|
|
109
|
FK506 ameliorates cell death features in Huntington's disease striatal cell models.
|
Neurochem Int
|
2011
|
0.80
|
|
110
|
Neuroprotective effects of statins in an in vitro model of Alzheimer's disease.
|
J Alzheimers Dis
|
2009
|
0.80
|
|
111
|
Modulation of endoplasmic reticulum stress: an opportunity to prevent neurodegeneration?
|
CNS Neurol Disord Drug Targets
|
2015
|
0.80
|
|
112
|
Hydroxytamoxifen protects against oxidative stress in brain mitochondria.
|
Biochem Pharmacol
|
2004
|
0.80
|
|
113
|
Activation of IGF-1 and insulin signaling pathways ameliorate mitochondrial function and energy metabolism in Huntington's Disease human lymphoblasts.
|
Mol Neurobiol
|
2014
|
0.80
|
|
114
|
Mitochondrial respiratory chain complex activity and bioenergetic alterations in human platelets derived from pre-symptomatic and symptomatic Huntington's disease carriers.
|
Mitochondrion
|
2013
|
0.79
|
|
115
|
Mitochondrial-dependent apoptosis in Huntington's disease human cybrids.
|
Exp Neurol
|
2010
|
0.79
|
|
116
|
The role of calcineurin in amyloid-beta-peptides-mediated cell death.
|
Brain Res
|
2005
|
0.79
|
|
117
|
Mitochondrial complex I dysfunction induced by cocaine and cocaine plus morphine in brain and liver mitochondria.
|
Toxicol Lett
|
2013
|
0.79
|
|
118
|
Transducing system operated by adenosine A(2A) receptors to facilitate acetylcholine release in the rat hippocampus.
|
Eur J Pharmacol
|
2002
|
0.79
|
|
119
|
Chronic hypoxia potentiates age-related oxidative imbalance in brain vessels and synaptosomes.
|
Curr Neurovasc Res
|
2010
|
0.79
|
|
120
|
BDNF and extracellular matrix regulate differentiation of mice neurosphere-derived cells into a GABAergic neuronal phenotype.
|
J Neurosci Res
|
2009
|
0.79
|
|
121
|
Inhibition of mitochondrial cytochrome c oxidase potentiates Aβ-induced ER stress and cell death in cortical neurons.
|
Mol Cell Neurosci
|
2012
|
0.79
|
|
122
|
No evidence of association or linkage disequilibrium between polymorphisms in the 5' upstream and coding regions of the dopamine D4 receptor gene and schizophrenia in a Portuguese population.
|
Am J Med Genet B Neuropsychiatr Genet
|
2004
|
0.79
|
|
123
|
Atypical presentation of Leber's hereditary optic neuropathy associated to mtDNA 11778G>A point mutation--A case report.
|
Eur J Paediatr Neurol
|
2007
|
0.79
|
|
124
|
Calpain-mediated MPP+ toxicity in mitochondrial DNA depleted cells.
|
Neurotox Res
|
2008
|
0.78
|
|
125
|
A possible role for oxidation stress in lymphoid leukaemias and therapeutic failure.
|
Leuk Res
|
2012
|
0.78
|
|
126
|
Bcl-2 overexpression protects against amyloid-beta and prion toxicity in GT1-7 neural cells.
|
J Alzheimers Dis
|
2007
|
0.78
|
|
127
|
Apoptotic cell death induced by hydrogen peroxide in NT2 parental and mitochondrial DNA depleted cells.
|
Neurochem Int
|
2004
|
0.78
|
|
128
|
Cobalt staining of hippocampal neurons mediated by non-desensitizing activation of AMPA but not kainate receptors.
|
Neuroreport
|
2003
|
0.77
|
|
129
|
Expression of AMPA/kainate receptors during development of chick embryo retina cells: in vitro versus in vivo studies.
|
Int J Dev Neurosci
|
2002
|
0.77
|
|
130
|
Enhanced amyloidogenic processing of amyloid precursor protein and cell death under prolonged endoplasmic reticulum stress in brain endothelial cells.
|
Mol Neurobiol
|
2014
|
0.77
|
|
131
|
Amyloid-beta peptide 1-42 causes microtubule deregulation through N-methyl-D-aspartate receptors in mature hippocampal cultures.
|
Curr Alzheimer Res
|
2012
|
0.77
|
|
132
|
Effect of chronic exposure to aluminium on isoform expression and activity of rat (Na+/K+)ATPase.
|
Toxicol Sci
|
2005
|
0.77
|
|
133
|
Effects of 1,4-dihydropyridine derivatives (cerebrocrast, gammapyrone, glutapyrone, and diethone) on mitochondrial bioenergetics and oxidative stress: a comparative study.
|
Mitochondrion
|
2003
|
0.77
|
|
134
|
Effect of free radicals on adenosine A(2A) and dopamine D2 receptors in the striatum of young adult and aged rats.
|
Neurochem Int
|
2004
|
0.77
|
|
135
|
Mitochondria as the target for mildronate's protective effects in azidothymidine (AZT)-induced toxicity of isolated rat liver mitochondria.
|
Cell Biochem Funct
|
2008
|
0.77
|
|
136
|
Aluminum accumulation and membrane fluidity alteration in synaptosomes isolated from rat brain cortex following aluminum ingestion: effect of cholesterol.
|
Neurosci Res
|
2002
|
0.77
|
|
137
|
Amyloid-beta disrupts calcium and redox homeostasis in brain endothelial cells.
|
Mol Neurobiol
|
2014
|
0.76
|
|
138
|
Is intraneuronal amyloid beta-peptide accumulation the trigger of Alzheimer's disease pathophysiology?
|
J Alzheimers Dis
|
2004
|
0.76
|
|
139
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