Published in J Biol Chem on April 23, 2007
ARF family G proteins and their regulators: roles in membrane transport, development and disease. Nat Rev Mol Cell Biol (2011) 3.38
Arl2-GTP and Arl3-GTP regulate a GDI-like transport system for farnesylated cargo. Nat Chem Biol (2011) 2.00
Regulation of actin cytoskeleton dynamics by Arf-family GTPases. Trends Cell Biol (2008) 1.58
Consensus nomenclature for the human ArfGAP domain-containing proteins. J Cell Biol (2008) 1.42
An alpha-helical extension of the ELMO1 pleckstrin homology domain mediates direct interaction to DOCK180 and is critical in Rac signaling. Mol Biol Cell (2008) 1.36
Toward a model for Arf GTPases as regulators of traffic at the Golgi. FEBS Lett (2009) 1.21
Opening up on ELMO regulation: New insights into the control of Rac signaling by the DOCK180/ELMO complex. Small GTPases (2011) 1.19
An evolutionarily conserved autoinhibitory molecular switch in ELMO proteins regulates Rac signaling. Curr Biol (2010) 1.15
Models for the functions of Arf GAPs. Semin Cell Dev Biol (2010) 1.14
Advantages and limitations of cell-based assays for GTPase activation and regulation. Cell Logist (2012) 1.09
Yeast and human Ysl2p/hMon2 interact with Gga adaptors and mediate their subcellular distribution. EMBO J (2008) 1.00
Mutations of the mouse ELMO domain containing 1 gene (Elmod1) link small GTPase signaling to actin cytoskeleton dynamics in hair cell stereocilia. PLoS One (2012) 0.96
The small GTPase ARL2 is required for cytokinesis in Trypanosoma brucei. Mol Biochem Parasitol (2010) 0.92
ELMO domains, evolutionary and functional characterization of a novel GTPase-activating protein (GAP) domain for Arf protein family GTPases. J Biol Chem (2012) 0.91
Membrane protein transport in photoreceptors: the function of PDEδ: the Proctor lecture. Invest Ophthalmol Vis Sci (2014) 0.90
An alteration in ELMOD3, an Arl2 GTPase-activating protein, is associated with hearing impairment in humans. PLoS Genet (2013) 0.89
The Arf family GTPase Arl4A complexes with ELMO proteins to promote actin cytoskeleton remodeling and reveals a versatile Ras-binding domain in the ELMO proteins family. J Biol Chem (2011) 0.88
The ARL2 GTPase is required for mitochondrial morphology, motility, and maintenance of ATP levels. PLoS One (2014) 0.86
Bivariate genome-wide association analysis of the growth and intake components of feed efficiency. PLoS One (2013) 0.84
Human immunodeficiency virus rev-binding protein is essential for influenza a virus replication and promotes genome trafficking in late-stage infection. J Virol (2011) 0.83
The emerging role of Arf/Arl small GTPases in cilia and ciliopathies. J Cell Biochem (2012) 0.83
Submicroscopic interstitial deletion of chromosome 11q22.3 in a girl with mild mental retardation and facial dysmorphism: Case report. Mol Cytogenet (2011) 0.82
Characterization of recombinant ELMOD (cell engulfment and motility domain) proteins as GTPase-activating proteins (GAPs) for ARF family GTPases. J Biol Chem (2014) 0.81
Higher order signaling: ARL2 as regulator of both mitochondrial fusion and microtubule dynamics allows integration of 2 essential cell functions. Small GTPases (2016) 0.78
Arl13b regulates Shh signaling from both inside and outside the cilium. Mol Biol Cell (2016) 0.77
ELMOD2 is anchored to lipid droplets by palmitoylation and regulates adipocyte triglyceride lipase recruitment. Mol Biol Cell (2015) 0.77
ClipR-59 interacts with Elmo2 and modulates myoblast fusion. J Biol Chem (2015) 0.77
A shortcut from GPCR signaling to Rac-mediated actin cytoskeleton through an ELMO/DOCK complex. Small GTPases (2012) 0.77
The abundance of the ARL2 GTPase and its GAP, ELMOD2, at mitochondria are modulated by the fusogenic activity of mitofusins and stressors. PLoS One (2017) 0.75
The ARL2 GTPase regulates mitochondrial fusion from the intermembrane space. Cell Logist (2017) 0.75
A proteomics approach to understanding protein ubiquitination. Nat Biotechnol (2003) 10.51
Quantitative proteomics reveals the function of unconventional ubiquitin chains in proteasomal degradation. Cell (2009) 6.16
A bacterial guanine nucleotide exchange factor activates ARF on Legionella phagosomes. Science (2002) 4.49
Relative and absolute quantification of postsynaptic density proteome isolated from rat forebrain and cerebellum. Mol Cell Proteomics (2006) 3.56
Clinical management of metabolic syndrome: report of the American Heart Association/National Heart, Lung, and Blood Institute/American Diabetes Association conference on scientific issues related to management. Circulation (2004) 3.35
Lysine propionylation and butyrylation are novel post-translational modifications in histones. Mol Cell Proteomics (2007) 3.09
A C-terminal translocation signal required for Dot/Icm-dependent delivery of the Legionella RalF protein to host cells. Proc Natl Acad Sci U S A (2004) 2.96
MicroRNA miR-137 regulates neuronal maturation by targeting ubiquitin ligase mind bomb-1. Stem Cells (2010) 2.89
Semiquantitative proteomic analysis of rat forebrain postsynaptic density fractions by mass spectrometry. J Biol Chem (2004) 2.84
Identification of neuronal RNA targets of TDP-43-containing ribonucleoprotein complexes. J Biol Chem (2010) 2.72
Prolyl 4-hydroxylation regulates Argonaute 2 stability. Nature (2008) 2.51
Regulation of estrogen receptor alpha by the SET7 lysine methyltransferase. Mol Cell (2008) 2.35
Analysis of the large inactive P-TEFb complex indicates that it contains one 7SK molecule, a dimer of HEXIM1 or HEXIM2, and two P-TEFb molecules containing Cdk9 phosphorylated at threonine 186. J Biol Chem (2005) 2.24
Automation of nanoscale microcapillary liquid chromatography-tandem mass spectrometry with a vented column. Anal Chem (2002) 2.22
Isoform-selective effects of the depletion of ADP-ribosylation factors 1-5 on membrane traffic. Mol Biol Cell (2005) 2.21
Cdk5-mediated inhibition of the protective effects of transcription factor MEF2 in neurotoxicity-induced apoptosis. Neuron (2003) 2.19
Structure and membrane interaction of myristoylated ARF1. Structure (2009) 2.12
The deubiquitinating enzyme ataxin-3, a polyglutamine disease protein, edits Lys63 linkages in mixed linkage ubiquitin chains. J Biol Chem (2008) 2.09
Site-specific ubiquitination exposes a linear motif to promote interferon-alpha receptor endocytosis. J Cell Biol (2007) 2.07
C3PO, an endoribonuclease that promotes RNAi by facilitating RISC activation. Science (2009) 2.04
Autophosphorylated CaMKIIalpha acts as a scaffold to recruit proteasomes to dendritic spines. Cell (2010) 2.02
Essential role of sequestosome 1/p62 in regulating accumulation of Lys63-ubiquitinated proteins. J Biol Chem (2008) 1.83
Human LSD2/KDM1b/AOF1 regulates gene transcription by modulating intragenic H3K4me2 methylation. Mol Cell (2010) 1.73
Arl2 and Arl3 regulate different microtubule-dependent processes. Mol Biol Cell (2006) 1.71
Adenosine production by human B cells and B cell-mediated suppression of activated T cells. Blood (2013) 1.70
Nuclear Akt associates with PKC-phosphorylated Ebp1, preventing DNA fragmentation by inhibition of caspase-activated DNase. EMBO J (2006) 1.67
Molecular determinants of polyubiquitin linkage selection by an HECT ubiquitin ligase. EMBO J (2006) 1.64
Proteomic characterization of postmortem amyloid plaques isolated by laser capture microdissection. J Biol Chem (2004) 1.58
Systematical optimization of reverse-phase chromatography for shotgun proteomics. J Proteome Res (2009) 1.53
Genetic inactivation of p62 leads to accumulation of hyperphosphorylated tau and neurodegeneration. J Neurochem (2008) 1.51
Arl13b regulates ciliogenesis and the dynamic localization of Shh signaling proteins. Mol Biol Cell (2011) 1.51
Polyubiquitin linkage profiles in three models of proteolytic stress suggest the etiology of Alzheimer disease. J Biol Chem (2011) 1.48
Systematic approach for validating the ubiquitinated proteome. Anal Chem (2008) 1.47
The cotranslational function of ribosome-associated Hsp70 in eukaryotic protein homeostasis. Cell (2013) 1.46
USP19 deubiquitinating enzyme supports cell proliferation by stabilizing KPC1, a ubiquitin ligase for p27Kip1. Mol Cell Biol (2008) 1.44
Munc18 interacting proteins: ADP-ribosylation factor-dependent coat proteins that regulate the traffic of beta-Alzheimer's precursor protein. J Biol Chem (2003) 1.42
Polyubiquitination of prolactin receptor stimulates its internalization, postinternalization sorting, and degradation via the lysosomal pathway. Mol Cell Biol (2008) 1.41
The lysine 48 and lysine 63 ubiquitin conjugates are processed differently by the 26 s proteasome. J Biol Chem (2009) 1.39
Efficient internalization of MHC I requires lysine-11 and lysine-63 mixed linkage polyubiquitin chains. Traffic (2009) 1.39
Loss of LR11/SORLA enhances early pathology in a mouse model of amyloidosis: evidence for a proximal role in Alzheimer's disease. J Neurosci (2008) 1.39
Clinical management of metabolic syndrome: report of the American Heart Association/National Heart, Lung, and Blood Institute/American Diabetes Association conference on scientific issues related to management. Arterioscler Thromb Vasc Biol (2004) 1.38
Ube2w and ataxin-3 coordinately regulate the ubiquitin ligase CHIP. Mol Cell (2011) 1.37
Dynamic structure of membrane-anchored Arf*GTP. Nat Struct Mol Biol (2010) 1.35
The structure of RalF, an ADP-ribosylation factor guanine nucleotide exchange factor from Legionella pneumophila, reveals the presence of a cap over the active site. J Biol Chem (2004) 1.33
Dissecting the ubiquitin pathway by mass spectrometry. Biochim Biophys Acta (2006) 1.32
Functional genomic analysis of the ADP-ribosylation factor family of GTPases: phylogeny among diverse eukaryotes and function in C. elegans. FASEB J (2004) 1.28
Proteomics analysis reveals novel components in the detergent-insoluble subproteome in Alzheimer's disease. J Proteome Res (2009) 1.27
Neuroprotective actions of PIKE-L by inhibition of SET proteolytic degradation by asparagine endopeptidase. Mol Cell (2008) 1.25
U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer's disease. Proc Natl Acad Sci U S A (2013) 1.23
Huntingtin-associated protein 1 interacts with Ahi1 to regulate cerebellar and brainstem development in mice. J Clin Invest (2008) 1.19
Nucleophosmin/B23, a nuclear PI(3,4,5)P(3) receptor, mediates the antiapoptotic actions of NGF by inhibiting CAD. Mol Cell (2005) 1.18
Modifications to the C-terminus of Arf1 alter cell functions and protein interactions. Traffic (2010) 1.17
Neuronal morphogenesis is regulated by the interplay between cyclin-dependent kinase 5 and the ubiquitin ligase mind bomb 1. J Neurosci (2007) 1.17
Identification and validation of eukaryotic aspartate and glutamate methylation in proteins. J Proteome Res (2008) 1.16
Multiplex SILAC analysis of a cellular TDP-43 proteinopathy model reveals protein inclusions associated with SUMOylation and diverse polyubiquitin chains. Mol Cell Proteomics (2010) 1.16
Protein kinase C inhibits autophagy and phosphorylates LC3. Biochem Biophys Res Commun (2010) 1.16
Models for the functions of Arf GAPs. Semin Cell Dev Biol (2010) 1.14
Phosphoproteomic analysis of human brain by calcium phosphate precipitation and mass spectrometry. J Proteome Res (2008) 1.13
Proteomic identification of novel proteins associated with Lewy bodies. Front Biosci (2008) 1.13
Characterization of polyubiquitin chain structure by middle-down mass spectrometry. Anal Chem (2008) 1.13
ARL2 and BART enter mitochondria and bind the adenine nucleotide transporter. Mol Biol Cell (2002) 1.11
A novel transferrin/TfR2-mediated mitochondrial iron transport system is disrupted in Parkinson's disease. Neurobiol Dis (2009) 1.11
Phosphoproteomic analysis reveals site-specific changes in GFAP and NDRG2 phosphorylation in frontotemporal lobar degeneration. J Proteome Res (2010) 1.10
Mint3/X11gamma is an ADP-ribosylation factor-dependent adaptor that regulates the traffic of the Alzheimer's Precursor protein from the trans-Golgi network. Mol Biol Cell (2007) 1.09
Genetic interactions link ARF1, YPT31/32 and TRS130. Yeast (2002) 1.07
Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis. J Proteome Res (2012) 1.05
Cytosolic Arl2 is complexed with cofactor D and protein phosphatase 2A. J Biol Chem (2003) 1.05
Quantitative analysis of the detergent-insoluble brain proteome in frontotemporal lobar degeneration using SILAC internal standards. J Proteome Res (2012) 1.05
Coaggregation of RNA-binding proteins in a model of TDP-43 proteinopathy with selective RGG motif methylation and a role for RRM1 ubiquitination. PLoS One (2012) 1.05
PHD3-dependent hydroxylation of HCLK2 promotes the DNA damage response. J Clin Invest (2012) 1.04
Adenosine A1 receptor activation as a brake on the microglial response after experimental traumatic brain injury in mice. J Neurotrauma (2010) 1.04
Protein Cysteines Map to Functional Networks According to Steady-state Level of Oxidation. J Proteomics Bioinform (2011) 1.04
Human BRE1 is an E3 ubiquitin ligase for Ebp1 tumor suppressor. Mol Biol Cell (2008) 1.03
Apolipoprotein A-IV expression in mouse liver enhances triglyceride secretion and reduces hepatic lipid content by promoting very low density lipoprotein particle expansion. Arterioscler Thromb Vasc Biol (2013) 1.02
Extracellular cAMP-adenosine pathways in the mouse kidney. Am J Physiol Renal Physiol (2011) 1.00