Published in Dev Dyn on November 01, 2006
Wnt/beta-catenin signaling is required for CNS, but not non-CNS, angiogenesis. Proc Natl Acad Sci U S A (2009) 3.17
Inflammation and the osteogenic regulation of vascular calcification: a review and perspective. Hypertension (2010) 1.61
Inhibition of canonical WNT signaling attenuates human leiomyoma cell growth. Fertil Steril (2014) 1.45
Beta-catenin/T-cell factor signaling is activated during lung injury and promotes the survival and migration of alveolar epithelial cells. J Biol Chem (2009) 1.35
Activation of beta-catenin signalling by GSK-3 inhibition increases p-glycoprotein expression in brain endothelial cells. J Neurochem (2008) 1.34
Rap1 and its effector KRIT1/CCM1 regulate beta-catenin signaling. Dis Model Mech (2009) 1.31
The canonical Wnt signaling antagonist DKK2 is an essential effector of PITX2 function during normal eye development. Dev Biol (2008) 1.31
Kruppel-like factor-4 transcriptionally regulates VE-cadherin expression and endothelial barrier function. Circ Res (2010) 1.29
The regulation of valvular and vascular sclerosis by osteogenic morphogens. Circ Res (2011) 1.29
Activation of vascular smooth muscle parathyroid hormone receptor inhibits Wnt/beta-catenin signaling and aortic fibrosis in diabetic arteriosclerosis. Circ Res (2010) 1.29
Vascular tissues are a primary source of BMP2 expression during bone formation induced by distraction osteogenesis. Bone (2012) 1.25
The chromatin-remodeling enzyme BRG1 modulates vascular Wnt signaling at two levels. Proc Natl Acad Sci U S A (2011) 1.21
A role for planar cell polarity signaling in angiogenesis. Angiogenesis (2008) 1.18
Gpr124 controls CNS angiogenesis and blood-brain barrier integrity by promoting ligand-specific canonical wnt signaling. Dev Cell (2014) 1.13
Macrophages and angiogenesis: a role for Wnt signaling. Vasc Cell (2012) 1.12
The endothelial transcription factor ERG promotes vascular stability and growth through Wnt/β-catenin signaling. Dev Cell (2015) 1.11
Dkk1 and MSX2-Wnt7b signaling reciprocally regulate the endothelial-mesenchymal transition in aortic endothelial cells. Arterioscler Thromb Vasc Biol (2013) 1.08
Canonical Wnt signaling negatively regulates platelet function. Proc Natl Acad Sci U S A (2009) 1.04
NANOG induction of fetal liver kinase-1 (FLK1) transcription regulates endothelial cell proliferation and angiogenesis. Blood (2010) 1.04
Differential expression of Wnts after spinal cord contusion injury in adult rats. PLoS One (2011) 1.03
Adenomatous polyposis coli regulates endothelial cell migration independent of roles in beta-catenin signaling and cell-cell adhesion. Mol Biol Cell (2010) 1.01
Hemodynamic activation of beta-catenin and T-cell-specific transcription factor signaling in vascular endothelium regulates fibronectin expression. Arterioscler Thromb Vasc Biol (2011) 0.99
Cell-cell interaction in the heart via Wnt/β-catenin pathway after cardiac injury. Cardiovasc Res (2014) 0.98
Paracrine activation of WNT/β-catenin pathway in uterine leiomyoma stem cells promotes tumor growth. Proc Natl Acad Sci U S A (2013) 0.98
Signaling "cross-talk" is integrated by transcription factors in the development of the anterior segment in the eye. Dev Dyn (2009) 0.96
Tumor endothelial marker 8 amplifies canonical Wnt signaling in blood vessels. PLoS One (2011) 0.95
Secreted frizzled-related protein 4: an angiogenesis inhibitor. Am J Pathol (2010) 0.94
Exercise training and peripheral arterial disease. Compr Physiol (2012) 0.90
Transcriptional regulation of SM22alpha by Wnt3a: convergence with TGFbeta(1)/Smad signaling at a novel regulatory element. J Mol Cell Cardiol (2009) 0.87
Wnt2 regulates progenitor proliferation in the developing ventral midbrain. J Biol Chem (2009) 0.87
Dkk-3 is elevated in CSF and plasma of Alzheimer's disease patients. J Neurochem (2009) 0.86
A novel signaling pathway regulates colon cancer angiogenesis through Norrin. Sci Rep (2014) 0.85
Endostar, a modified recombinant human endostatin, suppresses angiogenesis through inhibition of Wnt/β-catenin signaling pathway. PLoS One (2014) 0.85
TNF-induced activation of pulmonary microvessel endothelial cells: a role for GSK3beta. Am J Physiol Lung Cell Mol Physiol (2009) 0.82
The modulation of endothelial cell gene expression by green tea polyphenol-EGCG. Mol Nutr Food Res (2008) 0.80
Low-dose 6-bromoindirubin-3'-oxime induces partial dedifferentiation of endothelial cells to promote increased neovascularization. Stem Cells (2014) 0.80
Baicalin and geniposide inhibit the development of atherosclerosis by increasing Wnt1 and inhibiting dickkopf-related protein-1 expression. J Geriatr Cardiol (2016) 0.76
Prdm6 is essential for cardiovascular development in vivo. PLoS One (2013) 0.76
Actin-tethered junctional complexes in angiogenesis and lymphangiogenesis in association with vascular endothelial growth factor. Biomed Res Int (2015) 0.75
A complex interaction between Rickettsia conorii and Dickkopf-1--potential role in immune evasion mechanisms in endothelial cells. PLoS One (2012) 0.75
Wnt5a Regulates the Assembly of Human Adipose Derived Stromal Vascular Fraction-Derived Microvasculatures. PLoS One (2016) 0.75
Engineering vascularized skeletal muscle tissue. Nat Biotechnol (2005) 7.73
Soluble endoglin contributes to the pathogenesis of preeclampsia. Nat Med (2006) 6.21
VEGF-A stimulates lymphangiogenesis and hemangiogenesis in inflammatory neovascularization via macrophage recruitment. J Clin Invest (2004) 5.59
Inflammation-induced lymphangiogenesis in the cornea arises from CD11b-positive macrophages. J Clin Invest (2005) 3.77
Arteriolar and venular patterning in retinas of mice selectively expressing VEGF isoforms. J Clin Invest (2002) 3.70
Endogenous VEGF is required for visual function: evidence for a survival role on müller cells and photoreceptors. PLoS One (2008) 3.46
An essential role for RPE-derived soluble VEGF in the maintenance of the choriocapillaris. Proc Natl Acad Sci U S A (2009) 2.59
Skeletal defects in VEGF(120/120) mice reveal multiple roles for VEGF in skeletogenesis. Development (2002) 2.57
Development and pathology of the hyaloid, choroidal and retinal vasculature. Int J Dev Biol (2004) 2.56
VEGF164-mediated inflammation is required for pathological, but not physiological, ischemia-induced retinal neovascularization. J Exp Med (2003) 2.52
Decreased macrophage number and activation lead to reduced lymphatic vessel formation and contribute to impaired diabetic wound healing. Am J Pathol (2007) 2.27
Vascular endothelial growth factor localization in the adult. Am J Pathol (2006) 2.20
Epoxyeicosanoids stimulate multiorgan metastasis and tumor dormancy escape in mice. J Clin Invest (2011) 1.74
IGF2: epigenetic regulation and role in development and disease. Cytokine Growth Factor Rev (2008) 1.73
RhoA/ROCK signaling is essential for multiple aspects of VEGF-mediated angiogenesis. FASEB J (2010) 1.67
Tumor escape from endogenous, extracellular matrix-associated angiogenesis inhibitors by up-regulation of multiple proangiogenic factors. Clin Cancer Res (2008) 1.65
VEGF expression and receptor activation in the choroid during development and in the adult. Invest Ophthalmol Vis Sci (2006) 1.59
NLRP3 inflammasome activation in retinal pigment epithelial cells by lysosomal destabilization: implications for age-related macular degeneration. Invest Ophthalmol Vis Sci (2013) 1.58
VEGF and TGF-beta are required for the maintenance of the choroid plexus and ependyma. J Exp Med (2008) 1.54
Forty-year journey of angiogenesis translational research. Sci Transl Med (2011) 1.51
Analysis of hypoxia-related gene expression in sarcomas and effect of hypoxia on RNA interference of vascular endothelial cell growth factor A. Cancer Res (2005) 1.51
Roles for VEGF in the adult. Microvasc Res (2007) 1.48
TGF-beta is required for vascular barrier function, endothelial survival and homeostasis of the adult microvasculature. PLoS One (2009) 1.38
Transcriptional regulation of vascular endothelial growth factor in cancer. Cytokine Growth Factor Rev (2005) 1.35
Coordinated vascular endothelial growth factor expression and signaling during skeletal myogenic differentiation. Mol Biol Cell (2007) 1.26
Defective pulmonary development in the absence of heparin-binding vascular endothelial growth factor isoforms. Am J Respir Cell Mol Biol (2002) 1.25
Role of shear-stress-induced VEGF expression in endothelial cell survival. J Cell Sci (2012) 1.21
Expression and role of VEGF in the adult retinal pigment epithelium. Invest Ophthalmol Vis Sci (2011) 1.21
Retinal pigment epithelium and endothelial cell interaction causes retinal pigment epithelial barrier dysfunction via a soluble VEGF-dependent mechanism. Exp Eye Res (2003) 1.19
Pericyte isolation and use in endothelial/pericyte coculture models. Methods Enzymol (2008) 1.19
Signal transduction in vasculogenesis and developmental angiogenesis. Int J Dev Biol (2011) 1.17
Inhibition of VEGF or TGF-{beta} signaling activates endothelium and increases leukocyte rolling. Arterioscler Thromb Vasc Biol (2009) 1.14
The role of hypoxia in vascular injury and repair. Annu Rev Pathol (2008) 1.14
Endothelial-mesenchymal interactions in vitro reveal molecular mechanisms of smooth muscle/pericyte differentiation. Stem Cells Dev (2004) 1.13
Breast cancer cells secreted platelet-derived growth factor-induced motility of vascular smooth muscle cells is mediated through neuropilin-1. Mol Carcinog (2006) 1.13
Endothelial cell-astrocyte interactions and TGF beta are required for induction of blood-neural barrier properties. Brain Res Dev Brain Res (2004) 1.13
Proceedings of the Third International Symposium on Retinopathy of Prematurity: an update on ROP from the lab to the nursery (November 2003, Anaheim, California). Mol Vis (2006) 1.10
Contextual role for angiopoietins and TGFbeta1 in blood vessel stabilization. J Cell Sci (2007) 1.08
Epoxyeicosanoids promote organ and tissue regeneration. Proc Natl Acad Sci U S A (2013) 1.08
Wnt1 and Wnt5a affect endothelial proliferation and capillary length; Wnt2 does not. Growth Factors (2007) 1.03
Identification of genes involved in VEGF-mediated vascular morphogenesis using embryonic stem cell-derived cystic embryoid bodies. Lab Invest (2004) 1.02
Arterial versus venous endothelial cells. Cell Tissue Res (2008) 1.01
Differential effects of VEGFR-1 and VEGFR-2 inhibition on tumor metastases based on host organ environment. Cancer Res (2010) 1.01
Getting Tie(2)d up in angiogenesis. J Clin Invest (2002) 1.00
The role of RPE cell-associated VEGF₁₈₉ in choroidal endothelial cell transmigration across the RPE. Invest Ophthalmol Vis Sci (2011) 0.99
Vascular endothelial growth factor is important for brown adipose tissue development and maintenance. FASEB J (2013) 0.97
A brief history of anti-VEGF for the treatment of ocular angiogenesis. Am J Pathol (2012) 0.96
Functional analysis of a mutant form of the receptor tyrosine kinase Tie2 causing venous malformations. J Mol Med (Berl) (2004) 0.95
Repression of vascular endothelial growth factor expression by the zinc finger transcription factor ZNF24. Cancer Res (2007) 0.92
Molecular regulation of vascular endothelial growth factor expression in the retinal pigment epithelium. Mol Vis (2012) 0.92
CADASIL mutations impair Notch3 glycosylation by Fringe. Hum Mol Genet (2005) 0.90
VEGF expression is downregulated in nitrofen-induced congenital diaphragmatic hernia. J Pediatr Surg (2004) 0.90
Role of cell and matrix-bound VEGF isoforms in lens development. Invest Ophthalmol Vis Sci (2008) 0.90
The function of vascular endothelial growth factor. Biofactors (2009) 0.90
Therapeutic angiogenesis for cardiovascular disease. Curr Control Trials Cardiovasc Med (2001) 0.89
Vascular endothelial growth factor (VEGF) isoform regulation of early forebrain development. Dev Biol (2011) 0.89
The maintenance of lymphatic vessels in the cornea is dependent on the presence of macrophages. Invest Ophthalmol Vis Sci (2012) 0.86
The role of shear-induced transforming growth factor-β signaling in the endothelium. Arterioscler Thromb Vasc Biol (2013) 0.86
ErbB2 overexpression in mammary cells upregulates VEGF through the core promoter. Biochem Biophys Res Commun (2005) 0.86
Transcriptional repression of VEGF by ZNF24: mechanistic studies and vascular consequences in vivo. Blood (2012) 0.84
Expression and role of VEGF--a in the ciliary body. Invest Ophthalmol Vis Sci (2012) 0.83
Heat treatment of retinal pigment epithelium induces production of elastic lamina components and antiangiogenic activity. FASEB J (2011) 0.81
From pathobiology to the targeting of pericytes for the treatment of diabetic retinopathy. Curr Diab Rep (2015) 0.80
Regulation of soluble neuropilin 1, an endogenous angiogenesis inhibitor, in liver development and regeneration. Pathology (2014) 0.79
Culture of large vessel endothelial cells on floating collagen gels promotes a phenotype characteristic of endothelium in vivo. Differentiation (2004) 0.78
Tales of the cryptic: unveiling more angiogenesis inhibitors. Trends Mol Med (2002) 0.76
All vessels are not created equal. Am J Pathol (2013) 0.76
Judah Folkman's contribution to the inhibition of angiogenesis. Lymphat Res Biol (2008) 0.75
Editorial. Microvasc Res (2010) 0.75
Intracellular thiol redox status regulates lymphangiogenesis and dictates corneal limbal graft survival. Invest Ophthalmol Vis Sci (2009) 0.75