PIASy controls ubiquitination-dependent proteasomal degradation of Ets-1.

PubWeight™: 0.89‹?›

🔗 View Article (PMC 2267315)

Published in Biochem J on August 01, 2007

Authors

Tamotsu Nishida1, Motoko Terashima, Kiyoko Fukami, Yoshiji Yamada

Author Affiliations

1: Department of Human Functional Genomics, Life Science Research Center, Mie University, 1577 Kurima-machiya, Tsu 514-8507, Japan. nishida@gene.mie-u.ac.jp

Articles cited by this

The ubiquitin system. Annu Rev Biochem (1998) 43.36

SUMO: a history of modification. Mol Cell (2005) 10.40

SUMO-1 modification of IkappaBalpha inhibits NF-kappaB activation. Mol Cell (1998) 6.62

How the ubiquitin-proteasome system controls transcription. Nat Rev Mol Cell Biol (2003) 4.90

SUMO and ubiquitin in the nucleus: different functions, similar mechanisms? Genes Dev (2004) 4.80

The Ets family of transcription factors. Eur J Biochem (1993) 4.74

Phosphorylation-dependent ubiquitylation and degradation of androgen receptor by Akt require Mdm2 E3 ligase. EMBO J (2002) 3.27

The biology of the Ets1 proto-oncogene. Mol Cancer (2003) 2.88

Ets target genes: past, present and future. Oncogene (2000) 2.58

Specificity within the ets family of transcription factors. Adv Cancer Res (1998) 2.21

The ETS-domain transcription factor family. Int J Biochem Cell Biol (1997) 1.94

PIAS1 and PIASxalpha function as SUMO-E3 ligases toward androgen receptor and repress androgen receptor-dependent transcription. J Biol Chem (2002) 1.90

Diverse roles for ubiquitin-dependent proteolysis in transcriptional activation. Nat Cell Biol (2003) 1.79

Covalent attachment of the SUMO-1 protein to the negative regulatory domain of the c-Myb transcription factor modifies its stability and transactivation capacity. J Biol Chem (2002) 1.71

The ets gene family. Cell Growth Differ (1992) 1.67

Definition of an Ets1 protein domain required for nuclear localization in cells and DNA-binding activity in vitro. Mol Cell Biol (1989) 1.67

Gene regulation by Ets proteins. Biochim Biophys Acta (1993) 1.61

Expression of the transcription factor Ets-1 is an independent prognostic marker for relapse-free survival in breast cancer. Oncogene (2002) 1.34

PIAS-1 is a checkpoint regulator which affects exit from G1 and G2 by sumoylation of p73. Mol Cell Biol (2004) 1.33

Overexpression of the Ets-1 transcription factor in human breast cancer. Br J Cancer (2004) 1.20

Interactions between PIAS proteins and SOX9 result in an increase in the cellular concentrations of SOX9. J Biol Chem (2006) 1.10

Regulation of the Ets-1 transcription factor by sumoylation and ubiquitinylation. Oncogene (2006) 1.06

Ets1 is an effector of protein kinase Calpha in cancer cells. Oncogene (2005) 0.91

Expression of the ets-1 proto-oncogene in human breast carcinoma: differential expression with histological grading and growth pattern. Histol Histopathol (2005) 0.91

PIASy-mediated repression of the Ets-1 is independent of its sumoylation. Biochem Biophys Res Commun (2006) 0.90

Constitutive ubiquitination and degradation of c-myb by the 26S proteasome during proliferation and differentiation of myeloid cells. Neoplasma (2000) 0.80

Articles by these authors

Visualizing spatiotemporal dynamics of multicellular cell-cycle progression. Cell (2008) 10.49

Scale: a chemical approach for fluorescence imaging and reconstruction of transparent mouse brain. Nat Neurosci (2011) 7.37

Mitochondrial genome variation in eastern Asia and the peopling of Japan. Genome Res (2004) 3.34

Multiple roles of phosphoinositide-specific phospholipase C isozymes. BMB Rep (2008) 2.90

Association of gene polymorphisms with coronary artery disease in low- or high-risk subjects defined by conventional risk factors. J Am Coll Cardiol (2003) 1.97

Illuminating cell-cycle progression in the developing zebrafish embryo. Proc Natl Acad Sci U S A (2009) 1.88

Mitochondrial haplogroup N9a confers resistance against type 2 diabetes in Asians. Am J Hum Genet (2007) 1.76

Genetic risk and gene-environment interaction in coronary artery spasm in Japanese men and women. Eur Heart J (2004) 1.74

Phosphoinositide 3-kinase signaling pathway mediated by p110α regulates invadopodia formation. J Cell Biol (2011) 1.56

Cosignaling of NCAM via lipid rafts and the FGF receptor is required for neuritogenesis. J Cell Biol (2002) 1.55

Assessment of genetic risk factors for thoracic aortic aneurysm in hypertensive patients. Am J Hypertens (2008) 1.46

Recombinant phospholipase Czeta has high Ca2+ sensitivity and induces Ca2+ oscillations in mouse eggs. J Biol Chem (2003) 1.46

Lipid rafts and caveolin-1 are required for invadopodia formation and extracellular matrix degradation by human breast cancer cells. Cancer Res (2009) 1.42

Human mitotic spindle-associated protein PRC1 inhibits MgcRacGAP activity toward Cdc42 during the metaphase. J Biol Chem (2004) 1.41

X-linked inhibitor of apoptosis functions as ubiquitin ligase toward mature caspase-9 and cytosolic Smac/DIABLO. J Biochem (2005) 1.37

Pharmacological evidence for the involvement of diacylglycerol lipase in depolarization-induced endocanabinoid release. Neuropharmacology (2007) 1.31

Gene therapy for mitochondrial disease by delivering restriction endonuclease SmaI into mitochondria. J Biomed Sci (2002) 1.29

A novel phospholipase C, PLC(eta)2, is a neuron-specific isozyme. J Biol Chem (2005) 1.28

Homocysteine and coronary heart disease: meta-analysis of MTHFR case-control studies, avoiding publication bias. PLoS Med (2012) 1.27

Meta-analysis of the association of 4 angiotensinogen polymorphisms with essential hypertension: a role beyond M235T? Hypertension (2008) 1.25

Association of a 5178C-->A (Leu237Met) polymorphism in the mitochondrial DNA with a low prevalence of myocardial infarction in Japanese individuals. Atherosclerosis (2004) 1.24

Three endothelial nitric oxide (NOS3) gene polymorphisms in hypertensive and normotensive individuals: meta-analysis of 53 studies reveals evidence of publication bias. J Hypertens (2007) 1.14

Women with mitochondrial haplogroup N9a are protected against metabolic syndrome. Diabetes (2007) 1.11

Maintenance of tumor initiating cells of defined genetic composition by nucleostemin. Proc Natl Acad Sci U S A (2011) 1.09

The role of EF-hand domains and C2 domain in regulation of enzymatic activity of phospholipase Czeta. J Biol Chem (2005) 1.09

A novel GTPase, CRAG, mediates promyelocytic leukemia protein-associated nuclear body formation and degradation of expanded polyglutamine protein. J Cell Biol (2006) 1.07

Phosphatidylinositol 4,5-bisphosphate and PIP5-kinase Ialpha are required for invadopodia formation in human breast cancer cells. Cancer Sci (2010) 1.04

AT1 receptor blockade reduces cardiac calcineurin activity in hypertensive rats. Hypertension (2002) 1.04

Modulation of GABA(A) receptor phosphorylation and membrane trafficking by phospholipase C-related inactive protein/protein phosphatase 1 and 2A signaling complex underlying brain-derived neurotrophic factor-dependent regulation of GABAergic inhibition. J Biol Chem (2006) 1.03

Functional, biochemical, and chromatographic characterization of the complete [Ca2+]i oscillation-inducing activity of porcine sperm. Dev Biol (2005) 1.03

Attenuation of cardiac dysfunction by a PPAR-alpha agonist is associated with down-regulation of redox-regulated transcription factors. J Mol Cell Cardiol (2006) 1.02

Intrinsic cooperation between p16INK4a and p21Waf1/Cip1 in the onset of cellular senescence and tumor suppression in vivo. Cancer Res (2010) 1.02

Phospholipase Cdelta1 is required for skin stem cell lineage commitment. EMBO J (2003) 1.02

Reduced fertility of mouse epididymal sperm lacking Prss21/Tesp5 is rescued by sperm exposure to uterine microenvironment. Genes Cells (2008) 1.00

Lack of association of polymorphisms of the lymphotoxin alpha gene with myocardial infarction in Japanese. J Mol Med (Berl) (2004) 1.00

Distinctive changes in plasma membrane phosphoinositides underlie differential regulation of TRPV1 in nociceptive neurons. J Neurosci (2013) 0.99

Phospholipase C-related inactive protein is involved in trafficking of gamma2 subunit-containing GABA(A) receptors to the cell surface. J Neurosci (2007) 0.99

Phospholipase C-delta1 and -delta3 are essential in the trophoblast for placental development. Mol Cell Biol (2005) 0.99

Pravastatin increases survival and suppresses an increase in myocardial matrix metalloproteinase activity in a rat model of heart failure. Cardiovasc Res (2005) 0.98

Proteolytic processing of phospholipase Czeta and [Ca2+]i oscillations during mammalian fertilization. Dev Biol (2007) 0.98

Role of phospholipase C-L2, a novel phospholipase C-like protein that lacks lipase activity, in B-cell receptor signaling. Mol Cell Biol (2003) 0.96

Genetic factors for lone atrial fibrillation. Int J Mol Med (2007) 0.96

Mitochondrial haplogroup A is a genetic risk factor for atherothrombotic cerebral infarction in Japanese females. Mitochondrion (2006) 0.96

Mitochondrial haplogroup N9b is protective against myocardial infarction in Japanese males. Hum Genet (2006) 0.96

Phospholipase C-related but catalytically inactive protein is required for insulin-induced cell surface expression of gamma-aminobutyric acid type A receptors. J Biol Chem (2009) 0.94

Evidence that activation of Src family kinase is not required for fertilization-associated [Ca2+]i oscillations in mouse eggs. Reproduction (2004) 0.94

Roles of oxidative stress and Akt signaling in doxorubicin cardiotoxicity. Biochem Biophys Res Commun (2007) 0.93

Association of genetic variants with chronic kidney disease in Japanese individuals. Clin J Am Soc Nephrol (2009) 0.93

MARCKS regulates lamellipodia formation induced by IGF-I via association with PIP2 and beta-actin at membrane microdomains. J Cell Physiol (2009) 0.93

Lack of phospholipase C-delta1 induces skin inflammation. Biochem Biophys Res Commun (2007) 0.92

Association of genetic variants with myocardial infarction in Japanese individuals with metabolic syndrome. Atherosclerosis (2009) 0.92

Association of gene polymorphisms with coronary artery disease in individuals with or without nonfamilial hypercholesterolemia. Atherosclerosis (2004) 0.90

PIASy-mediated repression of the Ets-1 is independent of its sumoylation. Biochem Biophys Res Commun (2006) 0.90

Human plasma platelet-activating factor acetylhydrolase binds to all the murine lipoproteins, conferring protection against oxidative stress. Arterioscler Thromb Vasc Biol (2003) 0.90

Association of genetic variants with chronic kidney disease in individuals with different lipid profiles. Int J Mol Med (2009) 0.90

Phospholipase C-delta1 is an essential molecule downstream of Foxn1, the gene responsible for the nude mutation, in normal hair development. FASEB J (2007) 0.89

Ablation of the transcription factor Nrf2 promotes ischemia-induced neovascularization by enhancing the inflammatory response. Arterioscler Thromb Vasc Biol (2010) 0.89

Mitochondrial ATPase subunit 6 and cytochrome B gene polymorphisms in young obese adults. Biochem Biophys Res Commun (2002) 0.89

Gender differences in the association of gene polymorphisms with type 2 diabetes mellitus. Int J Mol Med (2007) 0.89

Phosphatidylinositol 5-phosphate 4-kinase type II beta is required for vitamin D receptor-dependent E-cadherin expression in SW480 cells. Biochem Biophys Res Commun (2011) 0.88

Phospholipase Cdelta3 regulates RhoA/Rho kinase signaling and neurite outgrowth. J Biol Chem (2010) 0.88

Association of genetic variants with hemorrhagic stroke in Japanese individuals. Int J Mol Med (2010) 0.88

A mitochondrial genotype associated with the development of autoimmune-related type 1 diabetes. Diabetes Care (2002) 0.87

Association of gene polymorphisms with chronic kidney disease in high- or low-risk subjects defined by conventional risk factors. Int J Mol Med (2009) 0.87

The newcomer in the integrin family: integrin α9 in biology and cancer. Adv Biol Regul (2012) 0.86

Genetic defect in phospholipase Cδ1 protects mice from obesity by regulating thermogenesis and adipogenesis. Diabetes (2011) 0.86

A role for the aryl hydrocarbon receptor in regulation of ischemia-induced angiogenesis. Arterioscler Thromb Vasc Biol (2007) 0.86

Genetic risk for restenosis after coronary stenting. Atherosclerosis (2007) 0.85

SMT3IP1, a nucleolar SUMO-specific protease, deconjugates SUMO-2 from nucleolar and cytoplasmic nucleophosmin. Biochem Biophys Res Commun (2008) 0.85

Association of genetic variants with myocardial infarction in Japanese individuals with chronic kidney disease. Thromb Haemost (2009) 0.85

Involvement of phospholipase C-related inactive protein in the mouse reproductive system through the regulation of gonadotropin levels. Biol Reprod (2009) 0.85

Attenuation of oxidative stress and cardiac dysfunction by bisoprolol in an animal model of dilated cardiomyopathy. Biochem Biophys Res Commun (2006) 0.84

Association of gene polymorphisms with myocardial infarction in individuals with or without conventional coronary risk factors. Int J Mol Med (2007) 0.84

Repression of E1AF transcriptional activity by sumoylation and PIASy. Biochem Biophys Res Commun (2007) 0.84

Association of candidate gene polymorphisms with chronic kidney disease in Japanese individuals with hypertension. Hypertens Res (2009) 0.83

Privacy-preserving genome-wide association studies on cloud environment using fully homomorphic encryption. BMC Med Inform Decis Mak (2015) 0.83

Association of gene polymorphisms with chronic kidney disease in Japanese individuals. Int J Mol Med (2009) 0.83

Synergistic effects of genetic variants of APOA5 and BTN2A1 on dyslipidemia or metabolic syndrome. Int J Mol Med (2012) 0.83

Roles of phospholipase C isozymes in organogenesis and embryonic development. Physiology (Bethesda) (2009) 0.83

Overexpression of calmodulin induces cardiac hypertrophy by a calcineurin-dependent pathway. Biochem Biophys Res Commun (2005) 0.83

Hair follicular expression and function of group X secreted phospholipase A2 in mouse skin. J Biol Chem (2011) 0.83

Association of a polymorphism of ABCB1 with obesity in Japanese individuals. Genomics (2008) 0.83

Association of genetic variants with chronic kidney disease in Japanese individuals with type 2 diabetes mellitus. Int J Mol Med (2009) 0.83

Association of genetic variants in SEMA3F, CLEC16A, LAMA3, and PCSK2 with myocardial infarction in Japanese individuals. Atherosclerosis (2009) 0.83

Identification of novel small compounds that restore E-cadherin expression and inhibit tumor cell motility and invasiveness. Biochem Pharmacol (2013) 0.82

Identification of a polymorphism of UCP3 associated with recurrent in-stent restenosis of coronary arteries. Int J Mol Med (2007) 0.82

Epidermal phospholipase Cδ1 regulates granulocyte counts and systemic interleukin-17 levels in mice. Nat Commun (2012) 0.82

Inhibition of ischemia-induced angiogenesis by benzo[a]pyrene in a manner dependent on the aryl hydrocarbon receptor. Biochem Biophys Res Commun (2009) 0.82

Association of genetic variants with myocardial infarction in individuals with or without hypertension or diabetes mellitus. Int J Mol Med (2009) 0.82

Oxido-reductive regulation of vascular remodeling by receptor tyrosine kinase ROS1. J Clin Invest (2014) 0.82

Phospholipase C delta-type consists of three isozymes: bovine PLCdelta2 is a homologue of human/mouse PLCdelta4. Biochem Biophys Res Commun (2004) 0.82

Association of a polymorphism of the apolipoprotein E gene with chronic kidney disease in Japanese individuals with metabolic syndrome. Genomics (2008) 0.82

GABA(A) receptor subunit alteration-dependent diazepam insensitivity in the cerebellum of phospholipase C-related inactive protein knockout mice. J Neurochem (2010) 0.81

Genetic risk for atherothrombotic cerebral infarction in individuals stratified by sex or conventional risk factors for atherosclerosis. Int J Mol Med (2006) 0.81

Association of a genetic variant of BTN2A1 with metabolic syndrome in East Asian populations. J Med Genet (2011) 0.81