Published in J Biol Chem on May 14, 2007
The pangenome structure of Escherichia coli: comparative genomic analysis of E. coli commensal and pathogenic isolates. J Bacteriol (2008) 6.02
Origins and virulence mechanisms of uropathogenic Escherichia coli. Exp Mol Pathol (2008) 2.81
Complicated catheter-associated urinary tract infections due to Escherichia coli and Proteus mirabilis. Clin Microbiol Rev (2008) 2.45
Mucosal immunization with iron receptor antigens protects against urinary tract infection. PLoS Pathog (2009) 2.14
Quantitative metabolomics reveals an epigenetic blueprint for iron acquisition in uropathogenic Escherichia coli. PLoS Pathog (2009) 1.83
Identifying gut microbe-host phenotype relationships using combinatorial communities in gnotobiotic mice. Sci Transl Med (2014) 1.69
The siderophore yersiniabactin binds copper to protect pathogens during infection. Nat Chem Biol (2012) 1.68
Fitness of Escherichia coli during urinary tract infection requires gluconeogenesis and the TCA cycle. PLoS Pathog (2009) 1.67
Escherichia coli global gene expression in urine from women with urinary tract infection. PLoS Pathog (2010) 1.65
Host-pathogen checkpoints and population bottlenecks in persistent and intracellular uropathogenic Escherichia coli bladder infection. FEMS Microbiol Rev (2012) 1.55
Regulation of mammalian siderophore 2,5-DHBA in the innate immune response to infection. J Exp Med (2014) 1.51
Intracellular Uropathogenic E. coli Exploits Host Rab35 for Iron Acquisition and Survival within Urinary Bladder Cells. PLoS Pathog (2015) 1.47
Waging war against uropathogenic Escherichia coli: winning back the urinary tract. Infect Immun (2009) 1.46
Redundancy and specificity of Escherichia coli iron acquisition systems during urinary tract infection. Infect Immun (2011) 1.41
Bacterial biofilms: development, dispersal, and therapeutic strategies in the dawn of the postantibiotic era. Cold Spring Harb Perspect Med (2013) 1.38
Patterns and scales in gastrointestinal microbial ecology. Gastroenterology (2009) 1.33
Urothelial cultures support intracellular bacterial community formation by uropathogenic Escherichia coli. Infect Immun (2009) 1.24
Use of zebrafish to probe the divergent virulence potentials and toxin requirements of extraintestinal pathogenic Escherichia coli. PLoS Pathog (2009) 1.21
A multiepitope subunit vaccine conveys protection against extraintestinal pathogenic Escherichia coli in mice. Infect Immun (2010) 1.19
Iron induces bimodal population development by Escherichia coli. Proc Natl Acad Sci U S A (2013) 1.16
Host-specific induction of Escherichia coli fitness genes during human urinary tract infection. Proc Natl Acad Sci U S A (2014) 1.14
Identification of functional LsrB-like autoinducer-2 receptors. J Bacteriol (2009) 1.06
Roles of iron acquisition systems in virulence of extraintestinal pathogenic Escherichia coli: salmochelin and aerobactin contribute more to virulence than heme in a chicken infection model. BMC Microbiol (2012) 1.06
Virulence plasmid harbored by uropathogenic Escherichia coli functions in acute stages of pathogenesis. Infect Immun (2010) 0.99
Asymmetric relationships between proteins shape genome evolution. Genome Biol (2009) 0.94
Pilicide ec240 disrupts virulence circuits in uropathogenic Escherichia coli. MBio (2014) 0.94
Cytotoxic necrotizing factor 1 and hemolysin from uropathogenic Escherichia coli elicit different host responses in the murine bladder. Infect Immun (2012) 0.93
Human Urinary Composition Controls Antibacterial Activity of Siderocalin. J Biol Chem (2015) 0.93
NGAL-Siderocalin in kidney disease. Biochim Biophys Acta (2012) 0.92
Lipocalin 2 imparts selective pressure on bacterial growth in the bladder and is elevated in women with urinary tract infection. J Immunol (2014) 0.91
Trade-off between iron uptake and protection against oxidative stress: deletion of cueO promotes uropathogenic Escherichia coli virulence in a mouse model of urinary tract infection. J Bacteriol (2008) 0.91
Defining protein expression in the urothelium: a problem of more than transitional interest. Am J Physiol Renal Physiol (2011) 0.90
Regulation of high-affinity iron acquisition homologues in the tsetse fly symbiont Sodalis glossinidius. J Bacteriol (2010) 0.88
The Neisseria meningitidis ZnuD zinc receptor contributes to interactions with epithelial cells and supports heme utilization when expressed in Escherichia coli. Infect Immun (2011) 0.88
Microbial Copper-binding Siderophores at the Host-Pathogen Interface. J Biol Chem (2015) 0.85
Metabolic Requirements of Escherichia coli in Intracellular Bacterial Communities during Urinary Tract Infection Pathogenesis. MBio (2016) 0.85
Virulence and Fitness Determinants of Uropathogenic Escherichia coli. Microbiol Spectr (2015) 0.85
Genome wide expression profiling reveals suppression of host defence responses during colonisation by Neisseria meningitides but not N. lactamica. PLoS One (2011) 0.84
Are you experienced? Understanding bladder innate immunity in the context of recurrent urinary tract infection. Curr Opin Infect Dis (2015) 0.84
Back to the metal age: battle for metals at the host-pathogen interface during urinary tract infection. Metallomics (2015) 0.83
What does it take to stick around? Molecular insights into biofilm formation by uropathogenic Escherichia coli. Virulence (2012) 0.82
Transcriptional responses of uropathogenic Escherichia coli to increased environmental osmolality caused by salt or urea. Infect Immun (2012) 0.82
Metal selectivity by the virulence-associated yersiniabactin metallophore system. Metallomics (2015) 0.82
Multi-omics integration accurately predicts cellular state in unexplored conditions for Escherichia coli. Nat Commun (2016) 0.80
Innate immunity of surfactant proteins A and D in urinary tract infection with uropathogenic Escherichia coli. Innate Immun (2015) 0.78
Drug and Vaccine Development for the Treatment and Prevention of Urinary Tract Infections. Microbiol Spectr (2016) 0.77
Identification of essential proteins based on ranking edge-weights in protein-protein interaction networks. PLoS One (2014) 0.77
Comparative tissue transcriptomics reveal prompt inter-organ communication in response to local bacterial kidney infection. BMC Genomics (2011) 0.77
Purine biosynthesis metabolically constrains intracellular survival of uropathogenic E. coli. Infect Immun (2016) 0.76
The Yersiniabactin-Associated ATP Binding Cassette Proteins YbtP and YbtQ Enhance Escherichia coli Fitness during High-Titer Cystitis. Infect Immun (2016) 0.75
Macrophagic control of the response to uropathogenic E. coli infection by regulation of iron retention in an IL-6-dependent manner. Immun Inflamm Dis (2016) 0.75
Invasion of Host Cells and Tissues by Uropathogenic Bacteria. Microbiol Spectr (2016) 0.75
Copper import in Escherichia coli by the yersiniabactin metallophore system. Nat Chem Biol (2017) 0.75
Fimbrial phase variation: stochastic or cooperative? Curr Genet (2015) 0.75
Epigenetic mechanisms regulate innate immunity against uropathogenic and commensal-like Escherichia coli in the surrogate insect model Galleria mellonella. Infect Immun (2017) 0.75
QIIME allows analysis of high-throughput community sequencing data. Nat Methods (2010) 85.34
A core gut microbiome in obese and lean twins. Nature (2008) 52.30
An obesity-associated gut microbiome with increased capacity for energy harvest. Nature (2006) 44.35
Microbial ecology: human gut microbes associated with obesity. Nature (2006) 36.98
Obesity alters gut microbial ecology. Proc Natl Acad Sci U S A (2005) 33.66
Metagenomic analysis of the human distal gut microbiome. Science (2006) 29.76
The human microbiome project. Nature (2007) 28.53
The gut microbiota as an environmental factor that regulates fat storage. Proc Natl Acad Sci U S A (2004) 26.56
Host-bacterial mutualism in the human intestine. Science (2005) 26.39
Bacterial community variation in human body habitats across space and time. Science (2009) 24.84
Evolution of mammals and their gut microbes. Science (2008) 21.40
Human gut microbiome viewed across age and geography. Nature (2012) 19.31
Ecological and evolutionary forces shaping microbial diversity in the human intestine. Cell (2006) 18.83
The effect of diet on the human gut microbiome: a metagenomic analysis in humanized gnotobiotic mice. Sci Transl Med (2009) 16.02
A genomic view of the human-Bacteroides thetaiotaomicron symbiosis. Science (2003) 12.57
Innate immunity and intestinal microbiota in the development of Type 1 diabetes. Nature (2008) 12.45
Worlds within worlds: evolution of the vertebrate gut microbiota. Nat Rev Microbiol (2008) 12.16
Diet-induced obesity is linked to marked but reversible alterations in the mouse distal gut microbiome. Cell Host Microbe (2008) 11.97
Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity. Nature (2012) 10.74
Developmental regulation of intestinal angiogenesis by indigenous microbes via Paneth cells. Proc Natl Acad Sci U S A (2002) 9.78
NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis. Cell (2011) 9.75
Mechanisms underlying the resistance to diet-induced obesity in germ-free mice. Proc Natl Acad Sci U S A (2007) 9.71
Reciprocal gut microbiota transplants from zebrafish and mice to germ-free recipients reveal host habitat selection. Cell (2006) 9.64
Diversity, stability and resilience of the human gut microbiota. Nature (2012) 9.09
Glycan foraging in vivo by an intestine-adapted bacterial symbiont. Science (2005) 9.08
Diet drives convergence in gut microbiome functions across mammalian phylogeny and within humans. Science (2011) 8.88
Gut microbiota from twins discordant for obesity modulate metabolism in mice. Science (2013) 8.81
How host-microbial interactions shape the nutrient environment of the mammalian intestine. Annu Rev Nutr (2002) 8.31
Human nutrition, the gut microbiome and the immune system. Nature (2011) 7.77
Minimum information about a marker gene sequence (MIMARKS) and minimum information about any (x) sequence (MIxS) specifications. Nat Biotechnol (2011) 7.53
Intracellular bacterial biofilm-like pods in urinary tract infections. Science (2003) 7.10
Organismal, genetic, and transcriptional variation in the deeply sequenced gut microbiomes of identical twins. Proc Natl Acad Sci U S A (2010) 7.09
Gut microbiomes of Malawian twin pairs discordant for kwashiorkor. Science (2013) 6.98
Moving pictures of the human microbiome. Genome Biol (2011) 6.72
Identifying genetic determinants needed to establish a human gut symbiont in its habitat. Cell Host Microbe (2009) 6.67
Angiogenins: a new class of microbicidal proteins involved in innate immunity. Nat Immunol (2003) 6.17
Viruses in the faecal microbiota of monozygotic twins and their mothers. Nature (2010) 5.92
Activated macrophages are an adaptive element of the colonic epithelial progenitor niche necessary for regenerative responses to injury. Proc Natl Acad Sci U S A (2004) 5.89
Evolution of symbiotic bacteria in the distal human intestine. PLoS Biol (2007) 5.79
Honor thy symbionts. Proc Natl Acad Sci U S A (2003) 5.72
Role of Escherichia coli curli operons in directing amyloid fiber formation. Science (2002) 5.58
Quality-filtering vastly improves diversity estimates from Illumina amplicon sequencing. Nat Methods (2012) 5.41
Mucosal glycan foraging enhances fitness and transmission of a saccharolytic human gut bacterial symbiont. Cell Host Microbe (2008) 5.39
IgA response to symbiotic bacteria as a mediator of gut homeostasis. Cell Host Microbe (2007) 5.18
Gnotobiotic zebrafish reveal evolutionarily conserved responses to the gut microbiota. Proc Natl Acad Sci U S A (2004) 5.16
The long-term stability of the human gut microbiota. Science (2013) 5.15
Identification of genes subject to positive selection in uropathogenic strains of Escherichia coli: a comparative genomics approach. Proc Natl Acad Sci U S A (2006) 5.13
A humanized gnotobiotic mouse model of host-archaeal-bacterial mutualism. Proc Natl Acad Sci U S A (2006) 5.04
Extensive personal human gut microbiota culture collections characterized and manipulated in gnotobiotic mice. Proc Natl Acad Sci U S A (2011) 4.85
Energy-balance studies reveal associations between gut microbes, caloric load, and nutrient absorption in humans. Am J Clin Nutr (2011) 4.60
Homeostasis and inflammation in the intestine. Cell (2010) 4.60
Getting a grip on things: how do communities of bacterial symbionts become established in our intestine? Nat Immunol (2004) 4.58
Enterobacteriaceae act in concert with the gut microbiota to induce spontaneous and maternally transmitted colitis. Cell Host Microbe (2010) 4.54
Immunoproliferative small intestinal disease associated with Campylobacter jejuni. N Engl J Med (2004) 4.47
The core gut microbiome, energy balance and obesity. J Physiol (2009) 4.45
Effects of the gut microbiota on host adiposity are modulated by the short-chain fatty-acid binding G protein-coupled receptor, Gpr41. Proc Natl Acad Sci U S A (2008) 4.45
Genomic and metabolic studies of the impact of probiotics on a model gut symbiont and host. PLoS Biol (2006) 4.27
The impact of a consortium of fermented milk strains on the gut microbiome of gnotobiotic mice and monozygotic twins. Sci Transl Med (2011) 4.24
Metagenomic approaches for defining the pathogenesis of inflammatory bowel diseases. Cell Host Microbe (2008) 4.14
Differentiation and developmental pathways of uropathogenic Escherichia coli in urinary tract pathogenesis. Proc Natl Acad Sci U S A (2004) 4.12
Characterizing a model human gut microbiota composed of members of its two dominant bacterial phyla. Proc Natl Acad Sci U S A (2009) 4.09
Complex glycan catabolism by the human gut microbiota: the Bacteroidetes Sus-like paradigm. J Biol Chem (2009) 4.05
Recognition and degradation of plant cell wall polysaccharides by two human gut symbionts. PLoS Biol (2011) 3.97
The biology and future prospects of antivirulence therapies. Nat Rev Microbiol (2008) 3.83
Detection of intracellular bacterial communities in human urinary tract infection. PLoS Med (2007) 3.54
Predicting a human gut microbiota's response to diet in gnotobiotic mice. Science (2011) 3.49
Mechanisms of uropathogenic Escherichia coli persistence and eradication from the urinary tract. Proc Natl Acad Sci U S A (2006) 3.36
Direct sequencing of the human microbiome readily reveals community differences. Genome Biol (2010) 3.34
Structural basis of tropism of Escherichia coli to the bladder during urinary tract infection. Mol Microbiol (2002) 3.26
The complete genome sequence of a chronic atrophic gastritis Helicobacter pylori strain: evolution during disease progression. Proc Natl Acad Sci U S A (2006) 3.07
Starch catabolism by a prominent human gut symbiont is directed by the recognition of amylose helices. Structure (2008) 3.02
Cohabiting family members share microbiota with one another and with their dogs. Elife (2013) 2.92
Manipulation of a nuclear NAD+ salvage pathway delays aging without altering steady-state NAD+ levels. J Biol Chem (2002) 2.91
Regulation of myocardial ketone body metabolism by the gut microbiota during nutrient deprivation. Proc Natl Acad Sci U S A (2009) 2.91
Genomic and metabolic adaptations of Methanobrevibacter smithii to the human gut. Proc Natl Acad Sci U S A (2007) 2.79
Fiber formation across the bacterial outer membrane by the chaperone/usher pathway. Cell (2008) 2.69
Effect of storage conditions on the assessment of bacterial community structure in soil and human-associated samples. FEMS Microbiol Lett (2010) 2.57
Chaperone priming of pilus subunits facilitates a topological transition that drives fiber formation. Cell (2002) 2.54
Small-molecule inhibitors target Escherichia coli amyloid biogenesis and biofilm formation. Nat Chem Biol (2009) 2.52
Molecular properties of adult mouse gastric and intestinal epithelial progenitors in their niches. J Biol Chem (2006) 2.49
Development of intracellular bacterial communities of uropathogenic Escherichia coli depends on type 1 pili. Cell Microbiol (2007) 2.48
Functional genomic and metabolic studies of the adaptations of a prominent adult human gut symbiont, Bacteroides thetaiotaomicron, to the suckling period. J Biol Chem (2006) 2.43
Dissecting the in vivo metabolic potential of two human gut acetogens. J Biol Chem (2010) 2.42
The abundance and variety of carbohydrate-active enzymes in the human gut microbiota. Nat Rev Microbiol (2013) 2.36
Meta-analyses of studies of the human microbiota. Genome Res (2013) 2.35
Molecular regulation of urothelial renewal and host defenses during infection with uropathogenic Escherichia coli. J Biol Chem (2001) 2.34
The convergence of carbohydrate active gene repertoires in human gut microbes. Proc Natl Acad Sci U S A (2008) 2.33
Molecular features of adult mouse small intestinal epithelial progenitors. Proc Natl Acad Sci U S A (2003) 2.33
Morphological plasticity as a bacterial survival strategy. Nat Rev Microbiol (2008) 2.28
Coordinate regulation of glycan degradation and polysaccharide capsule biosynthesis by a prominent human gut symbiont. J Biol Chem (2009) 2.21
Effect of trimethoprim-sulfamethoxazole on recurrent bacteriuria and bacterial persistence in mice infected with uropathogenic Escherichia coli. Infect Immun (2002) 2.20
Structural biology of the chaperone-usher pathway of pilus biogenesis. Nat Rev Microbiol (2009) 2.19
Laser capture microdissection of mouse intestine: characterizing mRNA and protein expression, and profiling intermediary metabolism in specified cell populations. Methods Enzymol (2002) 2.17
Tamm-Horsfall protein knockout mice are more prone to urinary tract infection: rapid communication. Kidney Int (2004) 2.17
Treatment and prevention of urinary tract infection with orally active FimH inhibitors. Sci Transl Med (2011) 2.16
Filamentation by Escherichia coli subverts innate defenses during urinary tract infection. Proc Natl Acad Sci U S A (2006) 2.15
A murine model of urinary tract infection. Nat Protoc (2009) 2.15
Secretion of curli fibre subunits is mediated by the outer membrane-localized CsgG protein. Mol Microbiol (2006) 2.14