Published in Biochem Biophys Res Commun on May 25, 2007
PIKfyve: Partners, significance, debates and paradoxes. Cell Biol Int (2008) 1.87
The physiological impact of the serum and glucocorticoid-inducible kinase SGK1. Curr Opin Nephrol Hypertens (2009) 1.35
Targeting SGK1 in diabetes. Expert Opin Ther Targets (2009) 1.02
SGK1-sensitive renal tubular glucose reabsorption in diabetes. Am J Physiol Renal Physiol (2009) 0.88
The nucleophosmin-anaplastic lymphoma kinase oncogene interacts, activates, and uses the kinase PIKfyve to increase invasiveness. J Biol Chem (2011) 0.83
Sodium-glucose cotransport. Curr Opin Nephrol Hypertens (2015) 0.82
Tumor suppressor gene adenomatous polyposis coli downregulates intestinal transport. Pflugers Arch (2011) 0.78
Regulation of ion channels and transporters by AMP-activated kinase (AMPK). Channels (Austin) (2013) 0.78
Sodium glucose cotransporter SGLT1 as a therapeutic target in diabetes mellitus. Expert Opin Ther Targets (2016) 0.77
Insulin and SGK1 reduce the function of Na+/monocarboxylate transporter 1 (SMCT1/SLC5A8). Am J Physiol Cell Physiol (2016) 0.75
(Patho)physiological significance of the serum- and glucocorticoid-inducible kinase isoforms. Physiol Rev (2006) 3.63
Akt signalling in health and disease. Cell Signal (2011) 3.42
Ceramide accumulation mediates inflammation, cell death and infection susceptibility in cystic fibrosis. Nat Med (2008) 3.41
Exploitation of KESTREL to identify NDRG family members as physiological substrates for SGK1 and GSK3. Biochem J (2004) 3.39
Scientifically unfounded precaution drives European Commission's recommendations on EDC regulation, while defying common sense, well-established science and risk assessment principles. Chem Biol Interact (2013) 3.10
Insulin signaling to the glomerular podocyte is critical for normal kidney function. Cell Metab (2010) 3.05
Na(+)-D-glucose cotransporter SGLT1 is pivotal for intestinal glucose absorption and glucose-dependent incretin secretion. Diabetes (2011) 2.65
Impaired renal Na(+) retention in the sgk1-knockout mouse. J Clin Invest (2002) 2.47
Activating mutation of the renal epithelial chloride channel ClC-Kb predisposing to hypertension. Hypertension (2004) 2.32
A global analysis of SNX27-retromer assembly and cargo specificity reveals a function in glucose and metal ion transport. Nat Cell Biol (2013) 2.18
Liver cell death and anemia in Wilson disease involve acid sphingomyelinase and ceramide. Nat Med (2007) 2.14
Expression and phosphorylation of the Na+-Cl- cotransporter NCC in vivo is regulated by dietary salt, potassium, and SGK1. Am J Physiol Renal Physiol (2009) 2.03
Mechanisms of suicidal erythrocyte death. Cell Physiol Biochem (2005) 2.02
The new anticonvulsant retigabine favors voltage-dependent opening of the Kv7.2 (KCNQ2) channel by binding to its activation gate. Mol Pharmacol (2005) 1.95
Connective tissue growth factor: a crucial cytokine-mediating cardiac fibrosis in ongoing enterovirus myocarditis. J Mol Med (Berl) (2007) 1.83
KCNQ1-dependent transport in renal and gastrointestinal epithelia. Proc Natl Acad Sci U S A (2005) 1.82
Role of Sgk1 in salt and potassium homeostasis. Am J Physiol Regul Integr Comp Physiol (2005) 1.81
A role for glycogen synthase kinase-3 in mitotic spindle dynamics and chromosome alignment. J Cell Sci (2003) 1.78
Aldosterone-induced Sgk1 relieves Dot1a-Af9-mediated transcriptional repression of epithelial Na+ channel alpha. J Clin Invest (2007) 1.69
Saturated fatty acids induce insulin resistance in human podocytes: implications for diabetic nephropathy. Nephrol Dial Transplant (2009) 1.68
Dynamic adhesion of eryptotic erythrocytes to endothelial cells via CXCL16/SR-PSOX. Am J Physiol Cell Physiol (2011) 1.67
The role of the CO2 laser in the management of laryngotracheal stenosis: a survey of 100 cases. Eur Arch Otorhinolaryngol (2005) 1.67
Spironolactone ameliorates PIT1-dependent vascular osteoinduction in klotho-hypomorphic mice. J Clin Invest (2013) 1.66
Genome-wide association study of height-adjusted BMI in childhood identifies functional variant in ADCY3. Obesity (Silver Spring) (2014) 1.65
Mutation of the PDK1 PH domain inhibits protein kinase B/Akt, leading to small size and insulin resistance. Mol Cell Biol (2008) 1.63
Suicidal death of erythrocytes in recurrent hemolytic uremic syndrome. J Mol Med (Berl) (2006) 1.62
GLUT1 mutations are a cause of paroxysmal exertion-induced dyskinesias and induce hemolytic anemia by a cation leak. J Clin Invest (2008) 1.60
Nephrin is critical for the action of insulin on human glomerular podocytes. Diabetes (2007) 1.55
Blunted DOCA/high salt induced albuminuria and renal tubulointerstitial damage in gene-targeted mice lacking SGK1. J Mol Med (Berl) (2006) 1.55
Protein kinase B phosphorylation of PIKfyve regulates the trafficking of GLUT4 vesicles. J Cell Sci (2004) 1.54
Molecular mechanisms of schizophrenia. Cell Physiol Biochem (2007) 1.53
Regulation of endocytic recycling of KCNQ1/KCNE1 potassium channels. Circ Res (2007) 1.52
Glucocorticoid activation of Na(+)/H(+) exchanger isoform 3 revisited. The roles of SGK1 and NHERF2. J Biol Chem (2001) 1.51
Position of aromatic residues in the S6 domain, not inactivation, dictates cisapride sensitivity of HERG and eag potassium channels. Proc Natl Acad Sci U S A (2002) 1.51
The human glomerular podocyte is a novel target for insulin action. Diabetes (2005) 1.49
Electrophysiological studies of malaria parasite-infected erythrocytes: current status. Int J Parasitol (2007) 1.47
Effective T-cell recall responses require the taurine transporter Taut. Eur J Immunol (2012) 1.42
Refinement of the binding site and mode of action of the anticonvulsant Retigabine on KCNQ K+ channels. Mol Pharmacol (2008) 1.42
Hyperaldosteronism, hypervolemia, and increased blood pressure in mice expressing defective APC. Am J Physiol Regul Integr Comp Physiol (2009) 1.42
Deregulation of the serum- and glucocorticoid-inducible kinase SGK1 in the endometrium causes reproductive failure. Nat Med (2011) 1.41
Effect of cyclosporine on parasitemia and survival of Plasmodium berghei infected mice. Biochem Biophys Res Commun (2008) 1.41
Decreased bone density and increased phosphaturia in gene-targeted mice lacking functional serum- and glucocorticoid-inducible kinase 3. Kidney Int (2011) 1.40
Plasmodium falciparum activates endogenous Cl(-) channels of human erythrocytes by membrane oxidation. EMBO J (2002) 1.40
Dexamethasone induces cell death in insulin-secreting cells, an effect reversed by exendin-4. Diabetes (2006) 1.35
Significance of SGK1 in the regulation of neuronal function. J Physiol (2010) 1.32
Hydration biomarkers in free-living adults with different levels of habitual fluid consumption. Br J Nutr (2012) 1.31
Killing me softly - suicidal erythrocyte death. Int J Biochem Cell Biol (2012) 1.31
High salt reduces the activation of IL-4- and IL-13-stimulated macrophages. J Clin Invest (2015) 1.30
Suicidal erythrocyte death in sepsis. J Mol Med (Berl) (2006) 1.30
Effects of I(Ks) channel inhibitors in insulin-secreting INS-1 cells. Pflugers Arch (2005) 1.29
Role of Ca2+-activated K+ channels in human erythrocyte apoptosis. Am J Physiol Cell Physiol (2003) 1.29
Universal cardiac induction of human pluripotent stem cells in two and three-dimensional formats: implications for in vitro maturation. Stem Cells (2015) 1.27
Enhanced programmed cell death of iron-deficient erythrocytes. FASEB J (2005) 1.26
A novel potassium channel in lymphocyte mitochondria. J Biol Chem (2005) 1.26
Erythrocyte programmed cell death. IUBMB Life (2008) 1.25
Chromanol 293B binding in KCNQ1 (Kv7.1) channels involves electrostatic interactions with a potassium ion in the selectivity filter. Mol Pharmacol (2007) 1.24
Serum- and glucocorticoid-inducible kinase 1 (SGK1) mediates glucocorticoid-induced inhibition of insulin secretion. Diabetes (2005) 1.23
Modulation of potassium channel function confers a hyperproliferative invasive phenotype on embryonic stem cells. Proc Natl Acad Sci U S A (2008) 1.22
Regulation of glucose transporter SGLT1 by ubiquitin ligase Nedd4-2 and kinases SGK1, SGK3, and PKB. Obes Res (2004) 1.21
Impaired regulation of renal K+ elimination in the sgk1-knockout mouse. J Am Soc Nephrol (2004) 1.21
Mitochondrial potassium channel Kv1.3 mediates Bax-induced apoptosis in lymphocytes. Proc Natl Acad Sci U S A (2008) 1.20
Reconstitution of invertebrate glutamate receptor function depends on stargazin-like proteins. Proc Natl Acad Sci U S A (2006) 1.20
mTOR target NDRG1 confers MGMT-dependent resistance to alkylating chemotherapy. Proc Natl Acad Sci U S A (2013) 1.20
KV7 channelopathies. Pflugers Arch (2010) 1.20
Cloning, heterologous expression, and characterization of three aquaglyceroporins from Trypanosoma brucei. J Biol Chem (2004) 1.18
The molecular basis of insulin-stimulated glucose uptake: signalling, trafficking and potential drug targets. J Endocrinol (2009) 1.18
Phenotype of the taurine transporter knockout mouse. Methods Enzymol (2007) 1.16
Intracellular multiplication of Legionella pneumophila depends on host cell amino acid transporter SLC1A5. Mol Microbiol (2005) 1.16
Serum- and glucocorticoid-inducible kinase 1 (SGK1) controls Notch1 signaling by downregulation of protein stability through Fbw7 ubiquitin ligase. J Cell Sci (2010) 1.15
Evidence for the involvement of Plasmodium falciparum proteins in the formation of new permeability pathways in the erythrocyte membrane. Mol Microbiol (2006) 1.14
The serum and glucocorticoid-inducible kinase SGK1 and the Na+/H+ exchange regulating factor NHERF2 synergize to stimulate the renal outer medullary K+ channel ROMK1. J Am Soc Nephrol (2002) 1.14
Ceramide: physiological and pathophysiological aspects. Arch Biochem Biophys (2007) 1.14
Imaging of insulin signaling in skeletal muscle of living mice shows major role of T-tubules. Diabetes (2006) 1.14
Differential roles of S6 domain hinges in the gating of KCNQ potassium channels. Biophys J (2005) 1.13
Structural basis of slow activation gating in the cardiac I Ks channel complex. Cell Physiol Biochem (2011) 1.11
Targeted disruption of the protein kinase SGK3/CISK impairs postnatal hair follicle development. Mol Biol Cell (2004) 1.11
Modulation of whole-cell currents in Plasmodium falciparum-infected human red blood cells by holding potential and serum. J Physiol (2003) 1.10
Characterization of mouse amino acid transporter B0AT1 (slc6a19). Biochem J (2005) 1.10
SGK1-dependent cardiac CTGF formation and fibrosis following DOCA treatment. J Mol Med (Berl) (2006) 1.10
Blunted IgE-mediated activation of mast cells in mice lacking the Ca2+-activated K+ channel KCa3.1. J Immunol (2008) 1.09
Regulation of erythrocyte survival by AMP-activated protein kinase. FASEB J (2008) 1.08
The serum- and glucocorticoid-inducible kinase Sgk-1 is involved in pulmonary vascular remodeling: role in redox-sensitive regulation of tissue factor by thrombin. Circ Res (2006) 1.08
Inhibition of erythrocyte cation channels by erythropoietin. J Am Soc Nephrol (2003) 1.08
Sgk1 activates MDM2-dependent p53 degradation and affects cell proliferation, survival, and differentiation. J Mol Med (Berl) (2009) 1.08
Regulation of the glutamate transporter EAAT1 by the ubiquitin ligase Nedd4-2 and the serum and glucocorticoid-inducible kinase isoforms SGK1/3 and protein kinase B. J Neurochem (2003) 1.08
Blunted hypertensive effect of combined fructose and high-salt diet in gene-targeted mice lacking functional serum- and glucocorticoid-inducible kinase SGK1. Am J Physiol Regul Integr Comp Physiol (2005) 1.07
Activation of NHE3 by dexamethasone requires phosphorylation of NHE3 at Ser663 by SGK1. Am J Physiol Cell Physiol (2005) 1.07
Protein kinase C activation downregulates human organic anion transporter 1-mediated transport through carrier internalization. J Am Soc Nephrol (2003) 1.06
Post-translational regulation of EAAT2 function by co-expressed ubiquitin ligase Nedd4-2 is impacted by SGK kinases. J Neurochem (2006) 1.06
Modulation of the voltage-gated potassium channel Kv1.5 by the SGK1 protein kinase involves inhibition of channel ubiquitination. Cell Physiol Biochem (2008) 1.06
Serum- and glucocorticoid-regulated kinase (SGK1) gene and blood pressure. Hypertension (2002) 1.05