Published in Nat Neurosci on June 24, 2007
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Neural stem cells confer unique pinwheel architecture to the ventricular surface in neurogenic regions of the adult brain. Cell Stem Cell (2008) 4.90
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The TRIM-NHL protein TRIM32 activates microRNAs and prevents self-renewal in mouse neural progenitors. Cell (2009) 3.60
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Numb links extracellular cues to intracellular polarity machinery to promote chemotaxis. Dev Cell (2011) 1.60
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Cortical neural precursors inhibit their own differentiation via N-cadherin maintenance of beta-catenin signaling. Dev Cell (2010) 1.49
Neurons derive from the more apical daughter in asymmetric divisions in the zebrafish neural tube. Nat Neurosci (2010) 1.47
Lis1-Nde1-dependent neuronal fate control determines cerebral cortical size and lamination. Hum Mol Genet (2008) 1.45
Neurogenesis at the brain-cerebrospinal fluid interface. Annu Rev Cell Dev Biol (2011) 1.42
The adenomatous polyposis coli protein is an essential regulator of radial glial polarity and construction of the cerebral cortex. Neuron (2009) 1.39
Mitotic spindle orientation predicts outer radial glial cell generation in human neocortex. Nat Commun (2013) 1.33
Beta-catenin-mediated Wnt signaling regulates neurogenesis in the ventral telencephalon. Nat Neurosci (2008) 1.32
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Numb controls E-cadherin endocytosis through p120 catenin with aPKC. Mol Biol Cell (2011) 1.27
Loss of RhoA in neural progenitor cells causes the disruption of adherens junctions and hyperproliferation. Proc Natl Acad Sci U S A (2011) 1.26
Numb regulates cell-cell adhesion and polarity in response to tyrosine kinase signalling. EMBO J (2009) 1.24
The apical complex couples cell fate and cell survival to cerebral cortical development. Neuron (2010) 1.22
Notch, neural stem cells, and brain tumors. Cold Spring Harb Symp Quant Biol (2008) 1.19
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Epicardial spindle orientation controls cell entry into the myocardium. Dev Cell (2010) 1.16
Junctional trafficking and epithelial morphogenesis. Curr Opin Genet Dev (2009) 1.14
Rbfox3-regulated alternative splicing of Numb promotes neuronal differentiation during development. J Cell Biol (2013) 1.13
Cell biology in neuroscience: Cellular and molecular mechanisms underlying axon formation, growth, and branching. J Cell Biol (2013) 1.12
Neural stem cells in the developing and adult brains. J Cell Physiol (2009) 1.11
Cajal-Retzius cells instruct neuronal migration by coincidence signaling between secreted and contact-dependent guidance cues. Neuron (2013) 1.11
Asymmetric cell division of stem and progenitor cells during homeostasis and cancer. Cell Mol Life Sci (2013) 1.11
Reinduction of ErbB2 in astrocytes promotes radial glial progenitor identity in adult cerebral cortex. Genes Dev (2007) 1.11
Adherens junction turnover: regulating adhesion through cadherin endocytosis, degradation, and recycling. Subcell Biochem (2012) 1.10
USP9X enhances the polarity and self-renewal of embryonic stem cell-derived neural progenitors. Mol Biol Cell (2009) 1.08
Intralineage directional Notch signaling regulates self-renewal and differentiation of asymmetrically dividing radial glia. Neuron (2012) 1.08
Developmentally regulated and evolutionarily conserved expression of SLITRK1 in brain circuits implicated in Tourette syndrome. J Comp Neurol (2009) 1.04
Cell biological regulation of division fate in vertebrate neuroepithelial cells. Dev Dyn (2011) 1.02
Development and distribution of neuronal cilia in mouse neocortex. J Comp Neurol (2012) 1.01
The role of ATP signaling in the migration of intermediate neuronal progenitors to the neocortical subventricular zone. Proc Natl Acad Sci U S A (2008) 1.00
MARCKS modulates radial progenitor placement, proliferation and organization in the developing cerebral cortex. Development (2009) 1.00
Two novel human NUMB isoforms provide a potential link between development and cancer. Neural Dev (2010) 1.00
Nuclear factor kappa B signaling initiates early differentiation of neural stem cells. Stem Cells (2012) 0.99
Scratch regulates neuronal migration onset via an epithelial-mesenchymal transition-like mechanism. Nat Neurosci (2013) 0.99
AKT activation by N-cadherin regulates beta-catenin signaling and neuronal differentiation during cortical development. Neural Dev (2013) 0.97
Cdc42 and Gsk3 modulate the dynamics of radial glial growth, inter-radial glial interactions and polarity in the developing cerebral cortex. Development (2010) 0.95
Regulation of lung cancer metastasis by Klf4-Numb-like signaling. Cancer Res (2013) 0.91
Numb regulates stability and localization of the mitotic kinase PLK1 and is required for transit through mitosis. Cancer Res (2012) 0.91
Genetics studies indicate that neural induction and early neuronal maturation are disturbed in autism. Front Cell Neurosci (2014) 0.89
The role of α-E-catenin in cerebral cortex development: radial glia specific effect on neuronal migration. Front Cell Neurosci (2014) 0.88
Drosophila E-cadherin and its binding partner Armadillo/ beta-catenin are required for axonal pathway choices in the developing larval brain. Dev Biol (2009) 0.88
Ccm3, a gene associated with cerebral cavernous malformations, is required for neuronal migration. Development (2014) 0.88
Numb family proteins are essential for cardiac morphogenesis and progenitor differentiation. Development (2013) 0.87
Prenatal deletion of the RNA-binding protein HuD disrupts postnatal cortical circuit maturation and behavior. J Neurosci (2014) 0.87
Numb: A new player in EMT. Cell Adh Migr (2010) 0.86
Genetic deletion of afadin causes hydrocephalus by destruction of adherens junctions in radial glial and ependymal cells in the midbrain. PLoS One (2013) 0.86
Post-transcriptional regulatory elements and spatiotemporal specification of neocortical stem cells and projection neurons. Neuroscience (2013) 0.86
LvNumb works synergistically with Notch signaling to specify non-skeletal mesoderm cells in the sea urchin embryo. Development (2008) 0.85
Subnuclear development of the zebrafish habenular nuclei requires ER translocon function. Dev Biol (2011) 0.85
Temporally defined neocortical translation and polysome assembly are determined by the RNA-binding protein Hu antigen R. Proc Natl Acad Sci U S A (2014) 0.85
Numb is required for the production of terminal asymmetric cell divisions in the developing mouse retina. J Neurosci (2012) 0.85
The Use of Induced Pluripotent Stem Cell Technology to Advance Autism Research and Treatment. Neurotherapeutics (2015) 0.84
Neocortical neurogenesis and neuronal migration. Wiley Interdiscip Rev Dev Biol (2012) 0.84
Post-transcriptional regulation in corticogenesis: how RNA-binding proteins help build the brain. Wiley Interdiscip Rev RNA (2015) 0.84
Numb, neurogenesis and epithelial polarity. Nat Neurosci (2007) 0.84
Strategies for analyzing neuronal progenitor development and neuronal migration in the developing cerebral cortex. Cereb Cortex (2010) 0.83
The tumor suppressive role of NUMB isoform 1 in esophageal squamous cell carcinoma. Oncotarget (2014) 0.82
Epithelial-to-Mesenchymal Plasticity Harnesses Endocytic Circuitries. Front Oncol (2015) 0.82
Hitting Them Where They Live: Targeting the Glioblastoma Perivascular Stem Cell Niche. Curr Pathobiol Rep (2013) 0.81
The tumor suppressor Apc controls planar cell polarities central to gut homeostasis. J Cell Biol (2012) 0.81
Thalamic WNT3 Secretion Spatiotemporally Regulates the Neocortical Ribosome Signature and mRNA Translation to Specify Neocortical Cell Subtypes. J Neurosci (2015) 0.81
Numb regulates acinar cell dedifferentiation and survival during pancreatic damage and acinar-to-ductal metaplasia. Gastroenterology (2013) 0.81
Numb family proteins: novel players in cardiac morphogenesis and cardiac progenitor cell differentiation. Biomol Concepts (2015) 0.80
Proliferative defects and formation of a double cortex in mice lacking Mltt4 and Cdh2 in the dorsal telencephalon. J Neurosci (2014) 0.80
Adapting for endocytosis: roles for endocytic sorting adaptors in directing neural development. Front Cell Neurosci (2015) 0.79
Asymmetric cell division of stem cells in the lung and other systems. Front Cell Dev Biol (2014) 0.79
Crucial roles of the Arp2/3 complex during mammalian corticogenesis. Development (2016) 0.79
New spin on an old transition: epithelial parallels in neuronal adhesion control. Trends Neurosci (2012) 0.79
N-cadherin-based adherens junction regulates the maintenance, proliferation, and differentiation of neural progenitor cells during development. Cell Adh Migr (2015) 0.79
Gli3 repressor controls cell fates and cell adhesion for proper establishment of neurogenic niche. Cell Rep (2014) 0.78
Numb deletion in POMC-expressing cells impairs pituitary intermediate lobe cell adhesion, progenitor cell localization, and neuro-intermediate lobe boundary formation. Mol Endocrinol (2010) 0.78
Aberrant expression of Notch1/numb/snail signaling, an epithelial mesenchymal transition related pathway, in adenomyosis. Reprod Biol Endocrinol (2015) 0.77
A Novel Role of Numb as A Regulator of Pro-inflammatory Cytokine Production in Macrophages in Response to Toll-like Receptor 4. Sci Rep (2015) 0.77
ASYMMETRIC CELL DIVISION: IMPLICATIONS FOR GLIOMA DEVELOPMENT AND TREATMENT. Transl Neurosci (2013) 0.77
NUMB negatively regulates the epithelial-mesenchymal transition of triple-negative breast cancer by antagonizing Notch signaling. Oncotarget (2016) 0.77
Bidirectional radial Ca(2+) activity regulates neurogenesis and migration during early cortical column formation. Sci Adv (2016) 0.77
The role of adherens junctions in the developing neocortex. Cell Adh Migr (2015) 0.76
Regulation of Numb isoform expression by activated ERK signaling. Oncogene (2016) 0.76
Numb regulates the polarized delivery of cyclic nucleotide-gated ion channels in rod photoreceptor cilia. J Neurosci (2014) 0.76
Zeb1 controls neuron differentiation and germinal zone exit by a mesenchymal-epithelial-like transition. Elife (2016) 0.76
Numb and Alzheimer's disease: the current picture. Front Neurosci (2012) 0.76
A restricted period for formation of outer subventricular zone defined by Cdh1 and Trnp1 levels. Nat Commun (2016) 0.76
The hominoid-specific gene TBC1D3 promotes generation of basal neural progenitors and induces cortical folding in mice. Elife (2016) 0.75
De novo mutations revealed by whole-exome sequencing are strongly associated with autism. Nature (2012) 13.61
Spatio-temporal transcriptome of the human brain. Nature (2011) 9.19
Sequence variants in SLITRK1 are associated with Tourette's syndrome. Science (2005) 8.20
Expression cloning of TMEM16A as a calcium-activated chloride channel subunit. Cell (2008) 7.79
Microarray analysis of microRNA expression in the developing mammalian brain. Genome Biol (2004) 7.33
Whole-exome sequencing identifies recessive WDR62 mutations in severe brain malformations. Nature (2010) 6.26
Functional and evolutionary insights into human brain development through global transcriptome analysis. Neuron (2009) 5.46
Hippocampal neuronal polarity specified by spatially localized mPar3/mPar6 and PI 3-kinase activity. Cell (2003) 4.84
Origin of GABAergic neurons in the human neocortex. Nature (2002) 4.40
Development of the human cerebral cortex: Boulder Committee revisited. Nat Rev Neurosci (2008) 4.01
Satb2 is a postmitotic determinant for upper-layer neuron specification in the neocortex. Neuron (2008) 3.57
Microtubule plus-end-tracking proteins target gap junctions directly from the cell interior to adherens junctions. Cell (2007) 3.52
Branching out: mechanisms of dendritic arborization. Nat Rev Neurosci (2010) 3.26
Cerebral ischemia-hypoxia induces intravascular coagulation and autophagy. Am J Pathol (2006) 3.18
Light-avoidance-mediating photoreceptors tile the Drosophila larval body wall. Nature (2010) 3.13
Control of dendritic branching and tiling by the Tricornered-kinase/Furry signaling pathway in Drosophila sensory neurons. Cell (2004) 3.13
Drosophila sensory neurons require Dscam for dendritic self-avoidance and proper dendritic field organization. Neuron (2007) 3.08
Coexpression networks implicate human midfetal deep cortical projection neurons in the pathogenesis of autism. Cell (2013) 2.94
Large-scale synthesis of nearly monodisperse CdSe/CdS core/shell nanocrystals using air-stable reagents via successive ion layer adsorption and reaction. J Am Chem Soc (2003) 2.87
Local generation of glia is a major astrocyte source in postnatal cortex. Nature (2012) 2.87
De novo gain-of-function KCNT1 channel mutations cause malignant migrating partial seizures of infancy. Nat Genet (2012) 2.86
Extraordinary neoteny of synaptic spines in the human prefrontal cortex. Proc Natl Acad Sci U S A (2011) 2.85
Serotonin modulates the response of embryonic thalamocortical axons to netrin-1. Nat Neurosci (2007) 2.70
Zfp312 is required for subcortical axonal projections and dendritic morphology of deep-layer pyramidal neurons of the cerebral cortex. Proc Natl Acad Sci U S A (2005) 2.66
Growing dendrites and axons differ in their reliance on the secretory pathway. Cell (2007) 2.51
Control of the postmating behavioral switch in Drosophila females by internal sensory neurons. Neuron (2009) 2.50
Drosophila egg-laying site selection as a system to study simple decision-making processes. Science (2008) 2.50
Genome-wide analyses identify transcription factors required for proper morphogenesis of Drosophila sensory neuron dendrites. Genes Dev (2006) 2.49
Molecular and morphological heterogeneity of neural precursors in the mouse neocortical proliferative zones. J Neurosci (2006) 2.49
A critical role of neural-specific JNK3 for ischemic apoptosis. Proc Natl Acad Sci U S A (2003) 2.47
Probing protein electrostatics with a synthetic fluorescent amino acid. Science (2002) 2.46
The role of the TRP channel NompC in Drosophila larval and adult locomotion. Neuron (2010) 2.44
Phosphatidylserine receptor is required for clearance of apoptotic cells. Science (2003) 2.38
Drosophila let-7 microRNA is required for remodeling of the neuromusculature during metamorphosis. Genes Dev (2008) 2.34
Dynein is required for polarized dendritic transport and uniform microtubule orientation in axons. Nat Cell Biol (2008) 2.33
Studies on expression and function of the TMEM16A calcium-activated chloride channel. Proc Natl Acad Sci U S A (2009) 2.33
Interaction between Reelin and Notch signaling regulates neuronal migration in the cerebral cortex. Neuron (2008) 2.31
Notch regulates cell fate and dendrite morphology of newborn neurons in the postnatal dentate gyrus. Proc Natl Acad Sci U S A (2007) 2.31
SOX5 postmitotically regulates migration, postmigratory differentiation, and projections of subplate and deep-layer neocortical neurons. Proc Natl Acad Sci U S A (2008) 2.26
TMEM16F forms a Ca2+-activated cation channel required for lipid scrambling in platelets during blood coagulation. Cell (2012) 2.24
Mammalian Par3 regulates progenitor cell asymmetric division via notch signaling in the developing neocortex. Neuron (2009) 2.23
Hardwiring the brain: endocannabinoids shape neuronal connectivity. Science (2007) 2.21
Projections of Drosophila multidendritic neurons in the central nervous system: links with peripheral dendrite morphology. Development (2007) 2.20
The tumour suppressor Hippo acts with the NDR kinases in dendritic tiling and maintenance. Nature (2006) 2.19
Primary cilia regulate hippocampal neurogenesis by mediating sonic hedgehog signaling. Proc Natl Acad Sci U S A (2008) 2.17
Activity- and mTOR-dependent suppression of Kv1.1 channel mRNA translation in dendrites. Science (2006) 2.16
Merging functional studies with structures of inward-rectifier K(+) channels. Nat Rev Neurosci (2003) 2.15
The control of dendrite development. Neuron (2003) 2.15
Peripheral multidendritic sensory neurons are necessary for rhythmic locomotion behavior in Drosophila larvae. Proc Natl Acad Sci U S A (2007) 2.14
Rapamycin ameliorates age-dependent obesity associated with increased mTOR signaling in hypothalamic POMC neurons. Neuron (2012) 2.13
Golgi outposts shape dendrite morphology by functioning as sites of acentrosomal microtubule nucleation in neurons. Neuron (2012) 2.12
Four-dimensional migratory coordinates of GABAergic interneurons in the developing mouse cortex. J Neurosci (2003) 2.12
APC and GSK-3beta are involved in mPar3 targeting to the nascent axon and establishment of neuronal polarity. Curr Biol (2004) 2.09
Drosophila NOMPC is a mechanotransduction channel subunit for gentle-touch sensation. Nature (2012) 2.07
The bHLH-PAS protein Spineless is necessary for the diversification of dendrite morphology of Drosophila dendritic arborization neurons. Genes Dev (2006) 2.06
Postnatal deletion of Numb/Numblike reveals repair and remodeling capacity in the subventricular neurogenic niche. Cell (2006) 2.06
Mitotic spindle rotation and mode of cell division in the developing telencephalon. Proc Natl Acad Sci U S A (2003) 2.06
Nanos and Pumilio are essential for dendrite morphogenesis in Drosophila peripheral neurons. Curr Biol (2004) 2.05
JNK-mediated induction of cyclooxygenase 2 is required for neurodegeneration in a mouse model of Parkinson's disease. Proc Natl Acad Sci U S A (2004) 2.05
Calcium-activated chloride channel TMEM16A modulates mucin secretion and airway smooth muscle contraction. Proc Natl Acad Sci U S A (2012) 1.97
Decision by division: making cortical maps. Trends Neurosci (2009) 1.97
Hypoxia-ischemia induces DNA synthesis without cell proliferation in dying neurons in adult rodent brain. J Neurosci (2004) 1.94
Selective depletion of molecularly defined cortical interneurons in human holoprosencephaly with severe striatal hypoplasia. Cereb Cortex (2009) 1.93
The first neurons of the human cerebral cortex. Nat Neurosci (2006) 1.91
Recessive LAMC3 mutations cause malformations of occipital cortical development. Nat Genet (2011) 1.89
Integrins regulate repulsion-mediated dendritic patterning of drosophila sensory neurons by restricting dendrites in a 2D space. Neuron (2012) 1.89
Prenatal exposure to ultrasound waves impacts neuronal migration in mice. Proc Natl Acad Sci U S A (2006) 1.86
Evolutionarily dynamic alternative splicing of GPR56 regulates regional cerebral cortical patterning. Science (2014) 1.85
The pRb/E2F cell-cycle pathway mediates cell death in Parkinson's disease. Proc Natl Acad Sci U S A (2007) 1.78
A conserved domain in axonal targeting of Kv1 (Shaker) voltage-gated potassium channels. Science (2003) 1.76
Genomic amplification and oncogenic properties of the KCNK9 potassium channel gene. Cancer Cell (2003) 1.76
Enhancer-driven membrane markers for analysis of nonautonomous mechanisms reveal neuron-glia interactions in Drosophila. Proc Natl Acad Sci U S A (2011) 1.76
Laminar and columnar development of barrel cortex relies on thalamocortical neurotransmission. Neuron (2013) 1.74
Efficient ends-out gene targeting in Drosophila. Genetics (2008) 1.74
Inactivation of Numb and Numblike in embryonic dorsal forebrain impairs neurogenesis and disrupts cortical morphogenesis. Neuron (2003) 1.73
Human-specific regulation of MeCP2 levels in fetal brains by microRNA miR-483-5p. Genes Dev (2013) 1.70
ATP-sensitive potassium channel traffic regulation by adenosine and protein kinase C. Neuron (2003) 1.70
Not(ch) just development: Notch signalling in the adult brain. Nat Rev Neurosci (2011) 1.69