Published in Science on May 25, 2007
Interneuron dysfunction in psychiatric disorders. Nat Rev Neurosci (2012) 2.87
Genetic dissection of behavioural and autonomic effects of Delta(9)-tetrahydrocannabinol in mice. PLoS Biol (2007) 2.08
CB2 receptor-mediated migration of immune cells: it can go either way. Br J Pharmacol (2007) 1.55
The CB(1) cannabinoid receptor drives corticospinal motor neuron differentiation through the Ctip2/Satb2 transcriptional regulation axis. J Neurosci (2012) 1.53
Calcium signaling in neuronal development. Cold Spring Harb Perspect Biol (2011) 1.52
Endocannabinoid signaling controls pyramidal cell specification and long-range axon patterning. Proc Natl Acad Sci U S A (2008) 1.47
Active endocannabinoids are secreted on extracellular membrane vesicles. EMBO Rep (2015) 1.45
Retracted Gene expression analysis indicates CB1 receptor upregulation in the hippocampus and neurotoxic effects in the frontal cortex 3 weeks after single-dose MDMA administration in Dark Agouti rats. BMC Genomics (2013) 1.39
Recruitment of prefrontal cortical endocannabinoid signaling by glucocorticoids contributes to termination of the stress response. J Neurosci (2011) 1.37
Cannabis and psychosis/schizophrenia: human studies. Eur Arch Psychiatry Clin Neurosci (2009) 1.37
Wiring the brain: the biology of neuronal guidance. Cold Spring Harb Perspect Biol (2010) 1.33
Adolescent cannabis use and psychosis: epidemiology and neurodevelopmental models. Br J Pharmacol (2010) 1.33
Alterations of endocannabinoid signaling, synaptic plasticity, learning, and memory in monoacylglycerol lipase knock-out mice. J Neurosci (2011) 1.32
Exploring a role for heteromerization in GPCR signalling specificity. Biochem J (2011) 1.31
Dynamic changes of the endogenous cannabinoid and opioid mesocorticolimbic systems during adolescence: THC effects. Eur Neuropsychopharmacol (2008) 1.28
Requirement of cannabinoid CB(1) receptors in cortical pyramidal neurons for appropriate development of corticothalamic and thalamocortical projections. Eur J Neurosci (2010) 1.26
Cannabinoids inhibit insulin receptor signaling in pancreatic β-cells. Diabetes (2011) 1.26
Alterations in the hippocampal endocannabinoid system in diet-induced obese mice. J Neurosci (2010) 1.19
Programming of neural cells by (endo)cannabinoids: from physiological rules to emerging therapies. Nat Rev Neurosci (2014) 1.18
Origin, early commitment, migratory routes, and destination of cannabinoid type 1 receptor-containing interneurons. Cereb Cortex (2009) 1.17
Gone to Pot - A Review of the Association between Cannabis and Psychosis. Front Psychiatry (2014) 1.14
Differential developmental trajectories for CB1 cannabinoid receptor expression in limbic/associative and sensorimotor cortical areas. Synapse (2011) 1.13
Regulation of CB1 cannabinoid receptor internalization by a promiscuous phosphorylation-dependent mechanism. J Neurochem (2008) 1.12
Miswiring the brain: Δ9-tetrahydrocannabinol disrupts cortical development by inducing an SCG10/stathmin-2 degradation pathway. EMBO J (2014) 1.11
Endocannabinoid-like N-arachidonoyl serine is a novel pro-angiogenic mediator. Br J Pharmacol (2010) 1.10
Endocannabinoid signaling is required for development and critical period plasticity of the whisker map in somatosensory cortex. Neuron (2009) 1.10
Cannabis Use during Adolescent Development: Susceptibility to Psychiatric Illness. Front Psychiatry (2013) 1.09
Wiring and firing neuronal networks: endocannabinoids take center stage. Curr Opin Neurobiol (2008) 1.08
Neurobiological consequences of maternal cannabis on human fetal development and its neuropsychiatric outcome. Eur Arch Psychiatry Clin Neurosci (2009) 1.06
Differential subcellular recruitment of monoacylglycerol lipase generates spatial specificity of 2-arachidonoyl glycerol signaling during axonal pathfinding. J Neurosci (2010) 1.06
The endocannabinoid system and the regulation of neural development: potential implications in psychiatric disorders. Eur Arch Psychiatry Clin Neurosci (2009) 1.04
The diacylglycerol lipases: structure, regulation and roles in and beyond endocannabinoid signalling. Philos Trans R Soc Lond B Biol Sci (2012) 0.99
Regulation of excitability and plasticity by endocannabinoids and PKA in developing hippocampus. Proc Natl Acad Sci U S A (2008) 0.98
The effects of prenatal marijuana exposure on delinquent behaviors are mediated by measures of neurocognitive functioning. Neurotoxicol Teratol (2011) 0.97
Long-term consequences of adolescent cannabinoid exposure in adult psychopathology. Front Neurosci (2014) 0.96
Lasting impacts of prenatal cannabis exposure and the role of endogenous cannabinoids in the developing brain. Future Neurol (2011) 0.92
Neuronal substrates and functional consequences of prenatal cannabis exposure. Eur Child Adolesc Psychiatry (2014) 0.92
Epigenetic Effects of Cannabis Exposure. Biol Psychiatry (2015) 0.91
Receptor heteromerization expands the repertoire of cannabinoid signaling in rodent neurons. PLoS One (2012) 0.91
Molecular model of cannabis sensitivity in developing neuronal circuits. Trends Pharmacol Sci (2011) 0.90
CB1 cannabinoid receptors couple to focal adhesion kinase to control insulin release. J Biol Chem (2013) 0.90
Endocannabinoid metabolism in the prefrontal cortex in schizophrenia. Schizophr Res (2013) 0.90
Regulation of neurite outgrowth by G(i/o) signaling pathways. Front Biosci (2008) 0.89
Cortical thickness in adolescent marijuana and alcohol users: A three-year prospective study from adolescence to young adulthood. Dev Cogn Neurosci (2015) 0.89
Developmental trajectory of the endocannabinoid system in human dorsolateral prefrontal cortex. BMC Neurosci (2012) 0.88
Endocannabinoid-dependent plasticity at spinal nociceptor synapses. J Physiol (2012) 0.88
Endocannabinoid-Goα signalling inhibits axon regeneration in Caenorhabditis elegans by antagonizing Gqα-PKC-JNK signalling. Nat Commun (2012) 0.88
Paracrine transactivation of the CB1 cannabinoid receptor by AT1 angiotensin and other Gq/11 protein-coupled receptors. J Biol Chem (2009) 0.87
CB1 receptor-mediated signaling underlies the hippocampal synaptic, learning, and memory deficits following treatment with JWH-081, a new component of spice/K2 preparations. Hippocampus (2014) 0.87
Endocannabinoids via CB₁ receptors act as neurogenic niche cues during cortical development. Philos Trans R Soc Lond B Biol Sci (2012) 0.87
Diacylglycerol lipase-alpha and -beta control neurite outgrowth in neuro-2a cells through distinct molecular mechanisms. Mol Pharmacol (2011) 0.87
Development of cannabinoid 1 receptor protein and messenger RNA in monkey dorsolateral prefrontal cortex. Cereb Cortex (2009) 0.87
Type-1 (CB1) cannabinoid receptor promotes neuronal differentiation and maturation of neural stem cells. PLoS One (2013) 0.86
Nerve growth factor scales endocannabinoid signaling by regulating monoacylglycerol lipase turnover in developing cholinergic neurons. Proc Natl Acad Sci U S A (2013) 0.86
Secretagogin is a Ca2+-binding protein identifying prospective extended amygdala neurons in the developing mammalian telencephalon. Eur J Neurosci (2010) 0.86
Anandamide-CB1 receptor signaling contributes to postnatal ethanol-induced neonatal neurodegeneration, adult synaptic, and memory deficits. J Neurosci (2013) 0.86
Individual differences in response to positive and negative stimuli: endocannabinoid-based insight on approach and avoidance behaviors. Front Syst Neurosci (2014) 0.85
Presynaptic CB1 receptors regulate synaptic plasticity at cerebellar parallel fiber synapses. J Neurophysiol (2010) 0.85
Sticking out of the crowd: the molecular identity and development of cholecystokinin-containing basket cells. J Physiol (2012) 0.85
Impact of Cannabis Use on the Development of Psychotic Disorders. Curr Addict Rep (2014) 0.85
Molecular mechanisms of maternal cannabis and cigarette use on human neurodevelopment. Eur J Neurosci (2011) 0.84
Downregulation of cannabinoid receptor 1 from neuropeptide Y interneurons in the basal ganglia of patients with Huntington's disease and mouse models. Eur J Neurosci (2012) 0.84
Endocannabinoid system: emerging role from neurodevelopment to neurodegeneration. Mini Rev Med Chem (2009) 0.84
Cannabinoid-induced actomyosin contractility shapes neuronal morphology and growth. Elife (2014) 0.83
Cannabinoid receptor CB2 modulates axon guidance. PLoS One (2013) 0.83
PKCepsilon regulates behavioral sensitivity, binding and tolerance to the CB1 receptor agonist WIN55,212-2. Neuropsychopharmacology (2009) 0.83
Elevation of endogenous anandamide impairs LTP, learning, and memory through CB1 receptor signaling in mice. Hippocampus (2014) 0.83
Developmental regulation of fear learning and anxiety behavior by endocannabinoids. Genes Brain Behav (2015) 0.82
Endocannabinoid system: potential novel targets for treatment of schizophrenia. Neurobiol Dis (2012) 0.82
Endocannabinoids modulate cortical development by configuring Slit2/Robo1 signalling. Nat Commun (2014) 0.81
Diacylglycerol lipaseα (DAGLα) and DAGLβ cooperatively regulate the production of 2-arachidonoyl glycerol in autaptic hippocampal neurons. Mol Pharmacol (2013) 0.81
Marijuana, Spice 'herbal high', and early neural development: implications for rescheduling and legalization. Drug Test Anal (2012) 0.81
Diacylglycerol lipase α manipulation reveals developmental roles for intercellular endocannabinoid signaling. Sci Rep (2013) 0.81
Modulation of early stress-induced neurobiological changes: a review of behavioural and pharmacological interventions in animal models. Transl Psychiatry (2014) 0.81
Cannabinoid receptor 1 signaling in embryo neurodevelopment. Birth Defects Res B Dev Reprod Toxicol (2012) 0.80
Heterogeneous presynaptic distribution of monoacylglycerol lipase, a multipotent regulator of nociceptive circuits in the mouse spinal cord. Eur J Neurosci (2014) 0.80
Characterisation of cannabinoid 1 receptor expression in the perikarya, and peripheral and spinal processes of primary sensory neurons. Brain Struct Funct (2012) 0.80
Cortical thinness and volume differences associated with marijuana abuse in emerging adults. Drug Alcohol Depend (2015) 0.80
Endocannabinoid modulation of cortical up-states and NREM sleep. PLoS One (2014) 0.79
Characterization of U-shape streamline fibers: Methods and applications. Med Image Anal (2014) 0.79
Ethanol exposure induces neonatal neurodegeneration by enhancing CB1R Exon1 histone H4K8 acetylation and up-regulating CB1R function causing neurobehavioral abnormalities in adult mice. Int J Neuropsychopharmacol (2014) 0.79
The Role of the Endocannabinoid System and Genetic Variation in Adolescent Brain Development. Neuropsychopharmacology (2017) 0.78
Endogenous cannabinoid signaling at inhibitory interneurons. Curr Opin Neurobiol (2013) 0.78
Chronic THC intake modifies fundamental cerebellar functions. J Clin Invest (2013) 0.78
Cannabinoid receptor-interacting protein 1a modulates CB1 receptor signaling and regulation. Mol Pharmacol (2015) 0.78
Developmental regulation of CB1-mediated spike-time dependent depression at immature mossy fiber-CA3 synapses. Sci Rep (2012) 0.78
Endocannabinoid signaling enhances visual responses through modulation of intracellular chloride levels in retinal ganglion cells. Elife (2016) 0.77
High fat diet and body weight have different effects on cannabinoid CB(1) receptor expression in rat nodose ganglia. Auton Neurosci (2013) 0.77
Cannabinoid mitigation of neuronal morphological change important to development and learning: insight from a zebra finch model of psychopharmacology. Life Sci (2012) 0.77
Postnatal ethanol exposure alters levels of 2-arachidonylglycerol-metabolizing enzymes and pharmacological inhibition of monoacylglycerol lipase does not cause neurodegeneration in neonatal mice. J Neurochem (2015) 0.77
The Cannabinoid Receptor CB1 Interacts with the WAVE1 Complex and Plays a Role in Actin Dynamics and Structural Plasticity in Neurons. PLoS Biol (2015) 0.77
Physiological impact of CB1 receptor expression by hippocampal GABAergic interneurons. Pflugers Arch (2016) 0.77
Fetal Alcohol Spectrum Disorder: Potential Role of Endocannabinoids Signaling. Brain Sci (2015) 0.76
Altered patterns of filopodia production in CHO cells heterologously expressing zebra finch CB(1) cannabinoid receptors. Cell Adh Migr (2012) 0.76
Maternal Malnutrition in the Etiopathogenesis of Psychiatric Diseases: Role of Polyunsaturated Fatty Acids. Brain Sci (2016) 0.76
Co-Ultramicronized Palmitoylethanolamide/Luteolin Promotes Neuronal Regeneration after Spinal Cord Injury. Front Pharmacol (2016) 0.76
Cannabinoid signaling system: does it play a function in cell proliferation and migration, neuritic elongation and guidance and synaptogenesis during brain ontogenesis? Cell Adh Migr (2008) 0.76
Differential Pharmacological Regulation of Sensorimotor Gating Deficit in CB1 Knockout Mice and Associated Neurochemical and Histological Alterations. Neuropsychopharmacology (2015) 0.76
Developmental increase in hippocampal endocannabinoid mobilization: role of metabotropic glutamate receptor subtype 5 and phospholipase C. J Neurophysiol (2014) 0.76
The effects of Δ(9)-tetrahydrocannabinol on the dopamine system. Nature (2016) 0.75
Green fluorescent protein expression and colocalization with calretinin, parvalbumin, and somatostatin in the GAD67-GFP knock-in mouse. J Comp Neurol (2003) 7.68
Microarray analysis of microRNA expression in the developing mammalian brain. Genome Biol (2004) 7.33
The endogenous cannabinoid system controls extinction of aversive memories. Nature (2002) 7.19
CB1 cannabinoid receptors and on-demand defense against excitotoxicity. Science (2003) 5.22
Identification and functional characterization of brainstem cannabinoid CB2 receptors. Science (2005) 5.12
Endocannabinoid activation at hepatic CB1 receptors stimulates fatty acid synthesis and contributes to diet-induced obesity. J Clin Invest (2005) 4.55
Origin of GABAergic neurons in the human neocortex. Nature (2002) 4.40
Nav1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation. J Neurosci (2007) 4.34
The endocannabinoid system controls key epileptogenic circuits in the hippocampus. Neuron (2006) 4.12
Pyramidal cell communication within local networks in layer 2/3 of rat neocortex. J Physiol (2003) 4.04
Development of the human cerebral cortex: Boulder Committee revisited. Nat Rev Neurosci (2008) 4.01
Perisomatic inhibition. Neuron (2007) 3.79
The endogenous cannabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesis. J Clin Invest (2003) 3.62
Controlling cell behavior electrically: current views and future potential. Physiol Rev (2005) 3.34
Cerebral ischemia-hypoxia induces intravascular coagulation and autophagy. Am J Pathol (2006) 3.18
Hepatic CB1 receptor is required for development of diet-induced steatosis, dyslipidemia, and insulin and leptin resistance in mice. J Clin Invest (2008) 3.13
Numb and Numbl are required for maintenance of cadherin-based adhesion and polarity of neural progenitors. Nat Neurosci (2007) 3.13
A specialized subclass of interneurons mediates dopaminergic facilitation of amygdala function. Neuron (2005) 2.99
Phospholipase C in living cells: activation, inhibition, Ca2+ requirement, and regulation of M current. J Gen Physiol (2005) 2.98
Paracrine activation of hepatic CB1 receptors by stellate cell-derived endocannabinoids mediates alcoholic fatty liver. Cell Metab (2008) 2.91
The emerging role of the endocannabinoid system in endocrine regulation and energy balance. Endocr Rev (2005) 2.90
Extraordinary neoteny of synaptic spines in the human prefrontal cortex. Proc Natl Acad Sci U S A (2011) 2.85
Nonpsychotropic cannabinoid receptors regulate microglial cell migration. J Neurosci (2003) 2.84
Molecular composition of the endocannabinoid system at glutamatergic synapses. J Neurosci (2006) 2.81
Cannabinoids mediate analgesia largely via peripheral type 1 cannabinoid receptors in nociceptors. Nat Neurosci (2007) 2.78
CB2: a cannabinoid receptor with an identity crisis. Br J Pharmacol (2010) 2.74
Lhx6 activity is required for the normal migration and specification of cortical interneuron subtypes. J Neurosci (2007) 2.74
Serotonin modulates the response of embryonic thalamocortical axons to netrin-1. Nat Neurosci (2007) 2.70
GABAergic neurons are less selective to stimulus orientation than excitatory neurons in layer II/III of visual cortex, as revealed by in vivo functional Ca2+ imaging in transgenic mice. J Neurosci (2007) 2.67
Analysis of the human tissue-specific expression by genome-wide integration of transcriptomics and antibody-based proteomics. Mol Cell Proteomics (2013) 2.53
The endogenous cannabinoid system protects against colonic inflammation. J Clin Invest (2004) 2.52
LRRK2 controls synaptic vesicle storage and mobilization within the recycling pool. J Neurosci (2011) 2.52
Storage and release of ATP from astrocytes in culture. J Biol Chem (2002) 2.50
Molecular and morphological heterogeneity of neural precursors in the mouse neocortical proliferative zones. J Neurosci (2006) 2.49
A critical role of neural-specific JNK3 for ischemic apoptosis. Proc Natl Acad Sci U S A (2003) 2.47
Increased LIS1 expression affects human and mouse brain development. Nat Genet (2009) 2.45
Allosteric modulation of the cannabinoid CB1 receptor. Mol Pharmacol (2005) 2.42
GPR55 is a cannabinoid receptor that increases intracellular calcium and inhibits M current. Proc Natl Acad Sci U S A (2008) 2.42
Building a new conceptual framework for receptor heteromers. Nat Chem Biol (2009) 2.41
Phosphatidylserine receptor is required for clearance of apoptotic cells. Science (2003) 2.38
In vivo labeling of parvalbumin-positive interneurons and analysis of electrical coupling in identified neurons. J Neurosci (2002) 2.38
The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors. Nat Neurosci (2010) 2.37
Experimental febrile seizures are precipitated by a hyperthermia-induced respiratory alkalosis. Nat Med (2006) 2.34
Amyloid beta-induced neuronal hyperexcitability triggers progressive epilepsy. J Neurosci (2009) 2.33
Endocannabinoid signaling in rat somatosensory cortex: laminar differences and involvement of specific interneuron types. J Neurosci (2005) 2.32
Interaction between Reelin and Notch signaling regulates neuronal migration in the cerebral cortex. Neuron (2008) 2.31
Notch regulates cell fate and dendrite morphology of newborn neurons in the postnatal dentate gyrus. Proc Natl Acad Sci U S A (2007) 2.31
Primary cilia regulate hippocampal neurogenesis by mediating sonic hedgehog signaling. Proc Natl Acad Sci U S A (2008) 2.17
Mitochondrial CB₁ receptors regulate neuronal energy metabolism. Nat Neurosci (2012) 2.15
Endocannabinoids acting at cannabinoid-1 receptors regulate cardiovascular function in hypertension. Circulation (2004) 2.15
Four-dimensional migratory coordinates of GABAergic interneurons in the developing mouse cortex. J Neurosci (2003) 2.12
Astrocyte-derived ATP induces vesicle shedding and IL-1 beta release from microglia. J Immunol (2005) 2.09
Genetic dissection of behavioural and autonomic effects of Delta(9)-tetrahydrocannabinol in mice. PLoS Biol (2007) 2.08
Mitotic spindle rotation and mode of cell division in the developing telencephalon. Proc Natl Acad Sci U S A (2003) 2.06
Depolarization-induced suppression of excitation in murine autaptic hippocampal neurones. J Physiol (2005) 2.06
JNK-mediated induction of cyclooxygenase 2 is required for neurodegeneration in a mouse model of Parkinson's disease. Proc Natl Acad Sci U S A (2004) 2.05
Visual receptive field structure of cortical inhibitory neurons revealed by two-photon imaging guided recording. J Neurosci (2009) 2.02
A subpopulation of olfactory bulb GABAergic interneurons is derived from Emx1- and Dlx5/6-expressing progenitors. J Neurosci (2007) 1.94
Hypoxia-ischemia induces DNA synthesis without cell proliferation in dying neurons in adult rodent brain. J Neurosci (2004) 1.94
Glial Nax channels control lactate signaling to neurons for brain [Na+] sensing. Neuron (2007) 1.91
Leptin regulates AMPA receptor trafficking via PTEN inhibition. J Neurosci (2010) 1.91
GSK-3 phosphorylation of the Alzheimer epitope within collapsin response mediator proteins regulates axon elongation in primary neurons. J Biol Chem (2004) 1.91
The first neurons of the human cerebral cortex. Nat Neurosci (2006) 1.91
Increased abundance of opioid receptor heteromers after chronic morphine administration. Sci Signal (2010) 1.90
Prenatal exposure to ultrasound waves impacts neuronal migration in mice. Proc Natl Acad Sci U S A (2006) 1.86
Pregnenolone can protect the brain from cannabis intoxication. Science (2014) 1.85
Potentiation of electrical and chemical synaptic transmission mediated by endocannabinoids. Neuron (2007) 1.85
Selective gating of glutamatergic inputs to excitatory neurons of amygdala by presynaptic GABAb receptor. Neuron (2009) 1.85
Transient neuronal populations are required to guide callosal axons: a role for semaphorin 3C. PLoS Biol (2009) 1.85
The GPR55 ligand L-alpha-lysophosphatidylinositol promotes RhoA-dependent Ca2+ signaling and NFAT activation. FASEB J (2008) 1.83
Random walk behavior of migrating cortical interneurons in the marginal zone: time-lapse analysis in flat-mount cortex. J Neurosci (2009) 1.83
Regulation of KCNQ2/KCNQ3 current by G protein cycling: the kinetics of receptor-mediated signaling by Gq. J Gen Physiol (2004) 1.82
Long-term plasticity of endocannabinoid signaling induced by developmental febrile seizures. Neuron (2003) 1.80
JWH018, a common constituent of 'Spice' herbal blends, is a potent and efficacious cannabinoid CB receptor agonist. Br J Pharmacol (2010) 1.79
Acid sphingomyelinase activity triggers microparticle release from glial cells. EMBO J (2009) 1.78
Eps8 regulates axonal filopodia in hippocampal neurons in response to brain-derived neurotrophic factor (BDNF). PLoS Biol (2009) 1.78
The pRb/E2F cell-cycle pathway mediates cell death in Parkinson's disease. Proc Natl Acad Sci U S A (2007) 1.78
CB2-receptor stimulation attenuates TNF-alpha-induced human endothelial cell activation, transendothelial migration of monocytes, and monocyte-endothelial adhesion. Am J Physiol Heart Circ Physiol (2007) 1.77