Published in CJEM on July 01, 2007
Community-associated methicillin-resistant Staphylococcus aureus: epidemiology and clinical consequences of an emerging epidemic. Clin Microbiol Rev (2010) 9.82
The Panton-Valentine leukocidin vaccine protects mice against lung and skin infections caused by Staphylococcus aureus USA300. Clin Microbiol Infect (2008) 2.14
High rates of Staphylococcus aureus USA400 infection, Northern Canada. Emerg Infect Dis (2011) 1.11
Severe necrotizing fasciitis in a human immunodeficiency virus-positive patient caused by methicillin-resistant Staphylococcus aureus. J Clin Microbiol (2008) 0.89
Fulminant necrotising fasciitis by community-acquired methicillin-resistant Staphylococcus aureus. BMJ Case Rep (2015) 0.75
Community-Associated Methicillin-Resistant Staphylococcus aureus in the Pediatric Population. J Pediatr Pharmacol Ther (2008) 0.75
Community acquired pneumonia with shock, severe hypoxemia and leucopenia: Is the etiology methicillin resistant Staphylococci? Saudi J Anaesth (2014) 0.75
Community-associated methicillin-resistant Staphylococcus aureus necrotizing pneumonia without evidence of antecedent viral upper respiratory infection. Can J Infect Dis Med Microbiol (2014) 0.75
Identification of severe acute respiratory syndrome in Canada. N Engl J Med (2003) 14.29
Hospital outbreak of Middle East respiratory syndrome coronavirus. N Engl J Med (2013) 11.85
One-year outcomes in survivors of the acute respiratory distress syndrome. N Engl J Med (2003) 11.77
Functional disability 5 years after acute respiratory distress syndrome. N Engl J Med (2011) 9.96
Critically Ill patients with 2009 influenza A(H1N1) in Mexico. JAMA (2009) 9.41
Outpatient gatifloxacin therapy and dysglycemia in older adults. N Engl J Med (2006) 7.01
High-frequency oscillation in early acute respiratory distress syndrome. N Engl J Med (2013) 6.56
Resistance to levofloxacin and failure of treatment of pneumococcal pneumonia. N Engl J Med (2002) 6.22
Driving pressure and survival in the acute respiratory distress syndrome. N Engl J Med (2015) 6.06
Characteristics and outcomes in adult patients receiving mechanical ventilation: a 28-day international study. JAMA (2002) 6.00
Antiviral therapy and outcomes of influenza requiring hospitalization in Ontario, Canada. Clin Infect Dis (2007) 5.39
Handheld computing in medicine. J Am Med Inform Assoc (2003) 5.23
Has mortality from acute respiratory distress syndrome decreased over time?: A systematic review. Am J Respir Crit Care Med (2008) 5.06
Neisseria gonorrhoeae treatment failure and susceptibility to cefixime in Toronto, Canada. JAMA (2013) 4.69
Complete nucleotide sequence of a 92-kilobase plasmid harboring the CTX-M-15 extended-spectrum beta-lactamase involved in an outbreak in long-term-care facilities in Toronto, Canada. Antimicrob Agents Chemother (2004) 4.46
Investigation of a nosocomial outbreak of severe acute respiratory syndrome (SARS) in Toronto, Canada. CMAJ (2003) 3.96
Health care-associated Clostridium difficile infection in adults admitted to acute care hospitals in Canada: a Canadian Nosocomial Infection Surveillance Program Study. Clin Infect Dis (2009) 3.86
Randomized controlled trial of chlorhexidine gluconate for washing, intranasal mupirocin, and rifampin and doxycycline versus no treatment for the eradication of methicillin-resistant Staphylococcus aureus colonization. Clin Infect Dis (2006) 3.80
High-frequency oscillatory ventilation for acute respiratory distress syndrome in adults: a randomized, controlled trial. Am J Respir Crit Care Med (2002) 3.43
Health care-associated Clostridium difficile infection in Canada: patient age and infecting strain type are highly predictive of severe outcome and mortality. Clin Infect Dis (2010) 3.42
An immunogenetic and molecular basis for differences in outcomes of invasive group A streptococcal infections. Nat Med (2002) 3.39
Empirical validation of guidelines for the management of pharyngitis in children and adults. JAMA (2004) 3.14
Critically ill patients with severe acute respiratory syndrome. JAMA (2003) 3.10
Canadian survey of the use of sedatives, analgesics, and neuromuscular blocking agents in critically ill patients. Crit Care Med (2006) 3.06
Triple reassortant H3N2 influenza A viruses, Canada, 2005. Emerg Infect Dis (2006) 3.05
West Nile virus infection in 2002: morbidity and mortality among patients admitted to hospital in southcentral Ontario. CMAJ (2003) 3.03
At the threshold: defining clinically meaningful resistance thresholds for antibiotic choice in community-acquired pneumonia. Clin Infect Dis (2008) 2.71
Evolutionary pathway to increased virulence and epidemic group A Streptococcus disease derived from 3,615 genome sequences. Proc Natl Acad Sci U S A (2014) 2.63
Predicting antimicrobial resistance in invasive pneumococcal infections. Clin Infect Dis (2005) 2.59
Laboratory characterization of methicillin-resistant Staphylococcus aureus in Canadian hospitals: results of 5 years of National Surveillance, 1995-1999. J Infect Dis (2002) 2.57
Acute respiratory distress syndrome: underrecognition by clinicians and diagnostic accuracy of three clinical definitions. Crit Care Med (2005) 2.47
Molecular complexity of successive bacterial epidemics deconvoluted by comparative pathogenomics. Proc Natl Acad Sci U S A (2010) 2.43
Managing skin and soft tissue infections: expert panel recommendations on key decision points. J Antimicrob Chemother (2003) 2.41
Two-year outcomes, health care use, and costs of survivors of acute respiratory distress syndrome. Am J Respir Crit Care Med (2006) 2.39
Reducing antimicrobial therapy for asymptomatic bacteriuria among noncatheterized inpatients: a proof-of-concept study. Clin Infect Dis (2014) 2.37
Airway pressures, tidal volumes, and mortality in patients with acute respiratory distress syndrome. Crit Care Med (2005) 2.37
Genome-wide molecular dissection of serotype M3 group A Streptococcus strains causing two epidemics of invasive infections. Proc Natl Acad Sci U S A (2004) 2.32
Genetic variability of human respiratory syncytial virus A strains circulating in Ontario: a novel genotype with a 72 nucleotide G gene duplication. PLoS One (2012) 2.21
High values of the pulmonary artery wedge pressure in patients with acute lung injury and acute respiratory distress syndrome. Intensive Care Med (2002) 2.15
SARS among critical care nurses, Toronto. Emerg Infect Dis (2004) 2.10
Healthcare-associated influenza in Canadian hospitals from 2006 to 2012. Infect Control Hosp Epidemiol (2014) 2.06
Detection of airborne severe acute respiratory syndrome (SARS) coronavirus and environmental contamination in SARS outbreak units. J Infect Dis (2005) 2.03
Invasive M1T1 group A Streptococcus undergoes a phase-shift in vivo to prevent proteolytic degradation of multiple virulence factors by SpeB. Mol Microbiol (2004) 1.99
Outcomes assessment of the surgical management of esophageal cancer in younger and older patients. Ann Thorac Surg (2012) 1.96
SARS in healthcare facilities, Toronto and Taiwan. Emerg Infect Dis (2004) 1.95
Severe group a streptococcal soft-tissue infections in Ontario: 1992-1996. Clin Infect Dis (2002) 1.93
Is a mass immunization program for pandemic (H1N1) 2009 good value for money? Evidence from the Canadian Experience. Vaccine (2010) 1.91
Recruitment maneuvers for acute lung injury: a systematic review. Am J Respir Crit Care Med (2008) 1.91
Mosaic prophages with horizontally acquired genes account for the emergence and diversification of the globally disseminated M1T1 clone of Streptococcus pyogenes. J Bacteriol (2005) 1.90
Exogenous natural surfactant for treatment of acute lung injury and the acute respiratory distress syndrome. Am J Respir Crit Care Med (2009) 1.83
Risk of infection following a visit to the emergency department: a cohort study. CMAJ (2012) 1.83
New Delhi metallo-beta-lactamase, Ontario, Canada. Emerg Infect Dis (2011) 1.81
Combining high-frequency oscillatory ventilation and recruitment maneuvers in adults with early acute respiratory distress syndrome: the Treatment with Oscillation and an Open Lung Strategy (TOOLS) Trial pilot study. Crit Care Med (2005) 1.81
Phylogenetic analysis reveals a cryptic species Blastomyces gilchristii, sp. nov. within the human pathogenic fungus Blastomyces dermatitidis. PLoS One (2013) 1.79
Integrated analysis of FOCUS 1 and FOCUS 2: randomized, doubled-blinded, multicenter phase 3 trials of the efficacy and safety of ceftaroline fosamil versus ceftriaxone in patients with community-acquired pneumonia. Clin Infect Dis (2010) 1.78
Pneumococcal pneumonia: potential for diagnosis through a urinary metabolic profile. J Proteome Res (2009) 1.78
Transmission of severe acute respiratory syndrome during intubation and mechanical ventilation. Am J Respir Crit Care Med (2004) 1.78
Illness in intensive care staff after brief exposure to severe acute respiratory syndrome. Emerg Infect Dis (2003) 1.76
Successful management of severe group A streptococcal soft tissue infections using an aggressive medical regimen including intravenous polyspecific immunoglobulin together with a conservative surgical approach. Scand J Infect Dis (2005) 1.75
Clostridium difficile infection in hospitals: a brewing storm. CMAJ (2004) 1.74
Update on herpes zoster vaccination: a family practitioner's guide. Can Fam Physician (2011) 1.74
New Delhi metallo-β-lactamase-1: local acquisition in Ontario, Canada, and challenges in detection. CMAJ (2011) 1.73
Mupirocin-resistant, methicillin-resistant Staphylococcus aureus strains in Canadian hospitals. Antimicrob Agents Chemother (2007) 1.72
A randomized trial of daily awakening in critically ill patients managed with a sedation protocol: a pilot trial. Crit Care Med (2008) 1.71
Alternative methods of estimating an incubation distribution: examples from severe acute respiratory syndrome. Epidemiology (2007) 1.70
Modulation of bacterial growth by tumor necrosis factor-alpha in vitro and in vivo. Am J Respir Crit Care Med (2003) 1.70
Treatment of Barrett's esophagus with early neoplasia: a comparison of endoscopic therapy and esophagectomy. Gastrointest Endosc (2008) 1.69
Clinical and epidemiologic features of group a streptococcal pneumonia in Ontario, Canada. Arch Intern Med (2003) 1.67
FOCUS 1: a randomized, double-blinded, multicentre, Phase III trial of the efficacy and safety of ceftaroline fosamil versus ceftriaxone in community-acquired pneumonia. J Antimicrob Chemother (2011) 1.66
A study of the physiologic responses to a lung recruitment maneuver in acute lung injury and acute respiratory distress syndrome. Respir Care (2008) 1.65
The FLAMES score accurately predicts mortality risk in burn patients. J Trauma (2008) 1.63
Risk factors for resistance to antimicrobial agents among nursing home residents. Am J Epidemiol (2003) 1.62
Modeling transmission of methicillin-resistant Staphylococcus aureus among patients admitted to a hospital. Infect Control Hosp Epidemiol (2005) 1.61
Use of a selective enrichment broth to recover Clostridium difficile from stool swabs stored under different conditions. J Clin Microbiol (2005) 1.61
Canadian guidelines for the management of acute exacerbations of chronic bronchitis: executive summary. Can Respir J (2003) 1.58
Guillain-Barré syndrome after influenza vaccination in adults: a population-based study. Arch Intern Med (2006) 1.57
Volume-outcome relationship in surgery for esophageal malignancy: systematic review and meta-analysis 2000-2011. J Gastrointest Surg (2011) 1.57
The society of thoracic surgeons guidelines on the diagnosis and staging of patients with esophageal cancer. Ann Thorac Surg (2013) 1.56
Severe acute respiratory syndrome (SARS): a year in review. Annu Rev Med (2005) 1.55
Shiga Toxin-Producing Escherichia coli Infection, Antibiotics, and Risk of Developing Hemolytic Uremic Syndrome: A Meta-analysis. Clin Infect Dis (2016) 1.53
Effect of multivitamin and mineral supplementation on episodes of infection in nursing home residents: a randomized, placebo-controlled study. J Am Geriatr Soc (2007) 1.52
Identification of a streptolysin S-associated gene cluster and its role in the pathogenesis of Streptococcus iniae disease. Infect Immun (2002) 1.52