China: the aging giant.

Urbanisation and health in China. Lancet (2012) 3.21

Health system reforms, violence against doctors and job satisfaction in the medical profession: a cross-sectional survey in Zhejiang Province, Eastern China. BMJ Open (2014) 1.31

Age, period and cohort effects on adult body mass index and overweight from 1991 to 2009 in China: the China Health and Nutrition Survey. Int J Epidemiol (2013) 1.20

China's rapidly aging population creates policy challenges in shaping a viable long-term care system. Health Aff (Millwood) (2012) 1.19

First-borns carry a higher metabolic risk in early adulthood: evidence from a prospective cohort study. PLoS One (2010) 1.05

Exploratory analysis of health-related quality of life among the empty-nest elderly in rural China: an empirical study in three economically developed cities in eastern China. Health Qual Life Outcomes (2014) 1.04

An industry in the making: the emergence of institutional elder care in urban china. J Am Geriatr Soc (2011) 1.00

Rural-urban differences in the long-term care of the disabled elderly in China. PLoS One (2013) 0.91

China's Population Policy at the Crossroads: Social Impacts and Prospects. Asian J Soc Sci (2015) 0.90

The aging population and development of geriatrics in China. J Am Geriatr Soc (2008) 0.84

Methodology of China's national study on the evaluation, early recognition, and treatment of psychological problems in the elderly: the China Longitudinal Aging Study (CLAS). Shanghai Arch Psychiatry (2013) 0.83

Effect of new disability subtype on 3-year mortality in Chinese older adults. J Am Geriatr Soc (2010) 0.81

A health policy and systems approach to addressing the growing burden of noncommunicable diseases in China. J Glob Health (2011) 0.81

Case-mix and quality indicators in Chinese elder care homes: are there differences between government-owned and private-sector facilities? J Am Geriatr Soc (2014) 0.79

A new classification of function and disability in China: subtypes based on performance-based and self-reported measures. J Aging Health (2012) 0.78

Outcomes of percutaneous coronary intervention in patients ≥ 75 years: one-center study in a Chinese patient group. J Geriatr Cardiol (2015) 0.77

Can medical insurance coverage reduce disparities of income in elderly patients requiring long-term care? The case of the People's Republic of China. Clin Interv Aging (2014) 0.77

Care services for elderly people with dementia in rural China: a case study. Bull World Health Organ (2016) 0.77

Dexmedetomidine Protects against Transient Global Cerebral Ischemia/Reperfusion Induced Oxidative Stress and Inflammation in Diabetic Rats. PLoS One (2016) 0.76

Self-management of coronary heart disease in older patients after elective percutaneous transluminal coronary angioplasty. J Geriatr Cardiol (2016) 0.75

China: the aging giant with an Achilles heel. J Am Geriatr Soc (2008) 0.75

Barriers to Reconstructive Hand Surgery for Rheumatoid Arthritis in China: A Multicenter Survey of Patients and Physicians. Plast Reconstr Surg Glob Open (2016) 0.75

The economic burden of dementia in China, 1990-2030: implications for health policy. Bull World Health Organ (2016) 0.75

Current situation of asthma-COPD overlap syndrome (ACOS) in Chinese patients older than 40 years with airflow limitation: rationale and design for a multicenter, cross-sectional trial (study protocol). J Thorac Dis (2016) 0.75

Screening method based on walking plantar impulse for detecting musculoskeletal senescence and injury. PLoS One (2013) 0.75

Prevalence and correlates of successful ageing: a comparative study between China and South Korea. Eur J Ageing (2014) 0.75

APD2: the updated antimicrobial peptide database and its application in peptide design. Nucleic Acids Res (2008) 4.23

Systematic identification of C. elegans miRISC proteins, miRNAs, and mRNA targets by their interactions with GW182 proteins AIN-1 and AIN-2. Mol Cell (2007) 4.22

Pivotal role of dermal IL-17-producing γδ T cells in skin inflammation. Immunity (2011) 3.75

Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. Nat Genet (2011) 3.68

A high-resolution map of segmental DNA copy number variation in the mouse genome. PLoS Genet (2006) 3.24

Identification of GATA3 as a breast cancer prognostic marker by global gene expression meta-analysis. Cancer Res (2005) 2.55

SLAM family markers resolve functionally distinct subpopulations of hematopoietic stem cells and multipotent progenitors. Cell Stem Cell (2013) 2.47

Genetic association of FOXO1A and FOXO3A with longevity trait in Han Chinese populations. Hum Mol Genet (2009) 2.34

Transposase-derived transcription factors regulate light signaling in Arabidopsis. Science (2007) 2.24

Serum proprotein convertase subtilisin/kexin type 9 and cell surface low-density lipoprotein receptor: evidence for a reciprocal regulation. Circulation (2013) 2.03

Towards precise classification of cancers based on robust gene functional expression profiles. BMC Bioinformatics (2005) 2.01

Human immunodeficiency virus type 1 enters brain microvascular endothelia by macropinocytosis dependent on lipid rafts and the mitogen-activated protein kinase signaling pathway. J Virol (2002) 1.97

MiRNA-miRNA synergistic network: construction via co-regulating functional modules and disease miRNA topological features. Nucleic Acids Res (2010) 1.94

Transmission of MDR and XDR tuberculosis in Shanghai, China. PLoS One (2009) 1.93

Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque. Nat Genet (2011) 1.92

Renal salt wasting and chronic dehydration in claudin-7-deficient mice. Am J Physiol Renal Physiol (2009) 1.90

Brain cannabinoid CB₂ receptors modulate cocaine's actions in mice. Nat Neurosci (2011) 1.88

Major taste loss in carnivorous mammals. Proc Natl Acad Sci U S A (2012) 1.81

The tumorigenic FGFR3-TACC3 gene fusion escapes miR-99a regulation in glioblastoma. J Clin Invest (2013) 1.76

trans-Diaqua-bis[5-carb-oxy-4-carboxyl-ato-2-(4-pyridinio)-1H-imidazol-1-ido-κN,O]iron(II). Acta Crystallogr Sect E Struct Rep Online (2009) 1.72

Comparison of different cortical connectivity estimators for high-resolution EEG recordings. Hum Brain Mapp (2007) 1.71

Olig2-positive progenitors in the embryonic spinal cord give rise not only to motoneurons and oligodendrocytes, but also to a subset of astrocytes and ependymal cells. Dev Biol (2006) 1.64

Correlation of iron in the hippocampus with MMSE in patients with Alzheimer's disease. J Magn Reson Imaging (2009) 1.64

High-efficiency and heritable gene targeting in mouse by transcription activator-like effector nucleases. Nucleic Acids Res (2013) 1.61

The Highwire ubiquitin ligase promotes axonal degeneration by tuning levels of Nmnat protein. PLoS Biol (2012) 1.60

Uptake, recycling, and antioxidant actions of alpha-lipoic acid in endothelial cells. Free Radic Biol Med (2002) 1.54

Effect of transcutaneous auricular vagus nerve stimulation on impaired glucose tolerance: a pilot randomized study. BMC Complement Altern Med (2014) 1.54

Allogeneic mesenchymal stem cell transplantation in severe and refractory systemic lupus erythematosus: 4 years of experience. Cell Transplant (2013) 1.53

Apparently low reproducibility of true differential expression discoveries in microarray studies. Bioinformatics (2008) 1.48

Salusin-β in rostral ventrolateral medulla increases sympathetic outflow and blood pressure via superoxide anions in hypertensive rats. J Hypertens (2014) 1.48

Cross-priming amplification for rapid detection of Mycobacterium tuberculosis in sputum specimens. J Clin Microbiol (2008) 1.47

Cannabinoid CB1 receptor antagonist AM251 inhibits cocaine-primed relapse in rats: role of glutamate in the nucleus accumbens. J Neurosci (2006) 1.46

Prioritizing risk pathways: a novel association approach to searching for disease pathways fusing SNPs and pathways. Bioinformatics (2008) 1.46

SubpathwayMiner: a software package for flexible identification of pathways. Nucleic Acids Res (2009) 1.45

Allelic variation of the Tas1r3 taste receptor gene selectively affects behavioral and neural taste responses to sweeteners in the F2 hybrids between C57BL/6ByJ and 129P3/J mice. J Neurosci (2004) 1.43

Sem1, the yeast ortholog of a human BRCA2-binding protein, is a component of the proteasome regulatory particle that enhances proteasome stability. J Cell Sci (2004) 1.42

QDMR: a quantitative method for identification of differentially methylated regions by entropy. Nucleic Acids Res (2011) 1.37

Plasticity in eucaryotic 20S proteasome ring assembly revealed by a subunit deletion in yeast. EMBO J (2004) 1.34

Disruption of the cellulose synthase gene, AtCesA8/IRX1, enhances drought and osmotic stress tolerance in Arabidopsis. Plant J (2005) 1.34

Dual-specificity histone demethylase KIAA1718 (KDM7A) regulates neural differentiation through FGF4. Cell Res (2010) 1.33

The CB1 receptor antagonist SR141716A selectively increases monoaminergic neurotransmission in the medial prefrontal cortex: implications for therapeutic actions. Br J Pharmacol (2003) 1.33

The relationship between body mass index and hip osteoarthritis: a systematic review and meta-analysis. Joint Bone Spine (2010) 1.33

Female oxytocin-deficient mice display enhanced anxiety-related behavior. Endocrinology (2003) 1.32

Motor imagery classification by means of source analysis for brain-computer interface applications. J Neural Eng (2004) 1.32

MiR-506 suppresses proliferation and induces senescence by directly targeting the CDK4/6-FOXM1 axis in ovarian cancer. J Pathol (2014) 1.31

Identification and expression analysis of miRNAs from nitrogen-fixing soybean nodules. Biochem Biophys Res Commun (2008) 1.30

A robust hybrid between genetic algorithm and support vector machine for extracting an optimal feature gene subset. Genomics (2005) 1.30

Correlation of three-dimensional structures with the antibacterial activity of a group of peptides designed based on a nontoxic bacterial membrane anchor. J Biol Chem (2004) 1.30

Heavy metal sources identification and sampling uncertainty analysis in a field-scale vegetable soil of Hangzhou, China. Environ Pollut (2008) 1.29

The Salt Overly Sensitive (SOS) pathway: established and emerging roles. Mol Plant (2013) 1.28

Allelic variation of the Tas1r3 taste receptor gene selectively affects taste responses to sweeteners: evidence from 129.B6-Tas1r3 congenic mice. Physiol Genomics (2007) 1.28

HHMD: the human histone modification database. Nucleic Acids Res (2009) 1.27

NDRG2 expression and mutation in human liver and pancreatic cancers. World J Gastroenterol (2004) 1.27

Macrophage EP4 deficiency increases apoptosis and suppresses early atherosclerosis. Cell Metab (2008) 1.25

A comparative study of salt tolerance parameters in 11 wild relatives of Arabidopsis thaliana. J Exp Bot (2010) 1.24

An endoplasmic reticulum response pathway mediates programmed cell death of root tip induced by water stress in Arabidopsis. New Phytol (2010) 1.23

Macrophage LRP-1 controls plaque cellularity by regulating efferocytosis and Akt activation. Arterioscler Thromb Vasc Biol (2010) 1.23

KLF6 induces apoptosis in prostate cancer cells through up-regulation of ATF3. J Biol Chem (2008) 1.23

N-Myc downstream-regulated gene 2 is involved in p53-mediated apoptosis. Nucleic Acids Res (2008) 1.22

Association between NSAIDs use and breast cancer risk: a systematic review and meta-analysis. Breast Cancer Res Treat (2008) 1.22

International Association of Gerontology and Geriatrics: a global agenda for clinical research and quality of care in nursing homes. J Am Med Dir Assoc (2011) 1.22

Umbilical cord mesenchymal stem cell transplantation in active and refractory systemic lupus erythematosus: a multicenter clinical study. Arthritis Res Ther (2014) 1.22

Cannabinoid CB1 receptor antagonists attenuate cocaine's rewarding effects: experiments with self-administration and brain-stimulation reward in rats. Neuropsychopharmacology (2007) 1.21

A cortical potential imaging study from simultaneous extra- and intracranial electrical recordings by means of the finite element method. Neuroimage (2006) 1.21

Claudin-7 inhibits human lung cancer cell migration and invasion through ERK/MAPK signaling pathway. Exp Cell Res (2011) 1.20

The analysis of the drug-targets based on the topological properties in the human protein-protein interaction network. J Drug Target (2009) 1.20

Down-regulation of TIPE2 mRNA expression in peripheral blood mononuclear cells from patients with systemic lupus erythematosus. Clin Immunol (2009) 1.20

Successful aging in Shanghai, China: definition, distribution and related factors. Int Psychogeriatr (2006) 1.18

Salt modulates gravity signaling pathway to regulate growth direction of primary roots in Arabidopsis. Plant Physiol (2007) 1.17

Association between embB codon 306 mutations and drug resistance in Mycobacterium tuberculosis. Antimicrob Agents Chemother (2007) 1.17

A regulatory effect of IL-21 on T follicular helper-like cell and B cell in rheumatoid arthritis. Arthritis Res Ther (2012) 1.17

YQA14: a novel dopamine D3 receptor antagonist that inhibits cocaine self-administration in rats and mice, but not in D3 receptor-knockout mice. Addict Biol (2011) 1.16

The evolution and pathogenic mechanisms of the rice sheath blight pathogen. Nat Commun (2013) 1.16

Gene therapy following subretinal AAV5 vector delivery is not affected by a previous intravitreal AAV5 vector administration in the partner eye. Mol Vis (2009) 1.16

Overexpression of SOS (Salt Overly Sensitive) genes increases salt tolerance in transgenic Arabidopsis. Mol Plant (2008) 1.16

Estimation of time-varying connectivity patterns through the use of an adaptive directed transfer function. IEEE Trans Biomed Eng (2008) 1.16

Self-association of human PCSK9 correlates with its LDLR-degrading activity. Biochemistry (2008) 1.16

IDH1/2 mutations target a key hallmark of cancer by deregulating cellular metabolism in glioma. Neuro Oncol (2013) 1.15

Is K-ras gene mutation a prognostic factor for colorectal cancer: a systematic review and meta-analysis. Dis Colon Rectum (2012) 1.15

Suicide among the elderly in mainland China. Psychogeriatrics (2009) 1.15

Unravelling the hidden heterogeneities of diffuse large B-cell lymphoma based on coupled two-way clustering. BMC Genomics (2007) 1.15

Estimation of the effective and functional human cortical connectivity with structural equation modeling and directed transfer function applied to high-resolution EEG. Magn Reson Imaging (2004) 1.15

Science and Government. Reforming China's S&T system. Science (2013) 1.14

H3.3 actively marks enhancers and primes gene transcription via opening higher-ordered chromatin. Genes Dev (2013) 1.14

Arabidopsis EIN2 modulates stress response through abscisic acid response pathway. Plant Mol Biol (2007) 1.14

Accuracy of image registration between MRI and light microscopy in the ex vivo brain. Magn Reson Imaging (2011) 1.14

Identification and profiling of microRNAs from skeletal muscle of the common carp. PLoS One (2012) 1.14

Prioritizing candidate disease miRNAs by topological features in the miRNA target-dysregulated network: case study of prostate cancer. Mol Cancer Ther (2011) 1.14

Inhibition of aberrant circulating Tfh cell proportions by corticosteroids in patients with systemic lupus erythematosus. PLoS One (2012) 1.13

Expression of the epithelial-mesenchymal transition-related proteins and their clinical significance in lung adenocarcinoma. Diagn Pathol (2013) 1.12

Quantitative effects of common genetic variations in the 3'UTR of the human LDL-receptor gene and their associations with plasma lipid levels in the Atherosclerosis Risk in Communities study. Hum Genet (2007) 1.12

Inhibition of NAALADase by 2-PMPA attenuates cocaine-induced relapse in rats: a NAAG-mGluR2/3-mediated mechanism. J Neurochem (2009) 1.11

Loci on chromosomes 2, 4, 9, and 16 for body weight, body length, and adiposity identified in a genome scan of an F2 intercross between the 129P3/J and C57BL/6ByJ mouse strains. Mamm Genome (2003) 1.11

Comprehensive analysis of the functional microRNA-mRNA regulatory network identifies miRNA signatures associated with glioma malignant progression. Nucleic Acids Res (2013) 1.11

Regulation of root-wave response by extra large and conventional G proteins in Arabidopsis thaliana. Plant J (2008) 1.11

Expression profiling of murine acute promyelocytic leukemia cells reveals multiple model-dependent progression signatures. Mol Cell Biol (2004) 1.10

A Wnt-Frz/Ror-Dsh pathway regulates neurite outgrowth in Caenorhabditis elegans. PLoS Genet (2010) 1.09

Combined deficiency of vitamins E and C causes paralysis and death in guinea pigs. Am J Clin Nutr (2003) 1.09

Isolation and characterization of Methanoculleus receptaculi sp. nov. from Shengli oil field, China. FEMS Microbiol Lett (2008) 1.09