Published in J Hypertens on May 01, 2014
Central blockade of salusin β attenuates hypertension and hypothalamic inflammation in spontaneously hypertensive rats. Sci Rep (2015) 0.86
Salusin-β induces foam cell formation and monocyte adhesion in human vascular smooth muscle cells via miR155/NOX2/NFκB pathway. Sci Rep (2016) 0.78
Salusin-β contributes to oxidative stress and inflammation in diabetic cardiomyopathy. Cell Death Dis (2017) 0.77
Salusin and central regulation of blood pressure in hypertension. J Hypertens (2014) 0.77
Silencing salusin-β attenuates cardiovascular remodeling and hypertension in spontaneously hypertensive rats. Sci Rep (2017) 0.75
Is the serum level of salusin-β associated with hypertension and atherosclerosis in the pediatric population? Pediatr Nephrol (2014) 0.75
Multiplex genome engineering using CRISPR/Cas systems. Science (2013) 55.53
Millisecond-timescale, genetically targeted optical control of neural activity. Nat Neurosci (2005) 28.08
One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering. Cell (2013) 24.00
DNA targeting specificity of RNA-guided Cas9 nucleases. Nat Biotechnol (2013) 19.99
Characterization of a novel coronavirus associated with severe acute respiratory syndrome. Science (2003) 18.34
RNA-guided editing of bacterial genomes using CRISPR-Cas systems. Nat Biotechnol (2013) 15.51
Targeting DNA double-strand breaks with TAL effector nucleases. Genetics (2010) 14.49
Whole-genome sequencing in a patient with Charcot-Marie-Tooth neuropathy. N Engl J Med (2010) 13.57
Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity. Cell (2013) 13.37
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25
Genome-wide association study identifies eight loci associated with blood pressure. Nat Genet (2009) 12.44
Driving fast-spiking cells induces gamma rhythm and controls sensory responses. Nature (2009) 11.74
Parvalbumin neurons and gamma rhythms enhance cortical circuit performance. Nature (2009) 10.79
Common genetic determinants of vitamin D insufficiency: a genome-wide association study. Lancet (2010) 8.89
Selection-free zinc-finger-nuclease engineering by context-dependent assembly (CoDA). Nat Methods (2010) 8.86
Phasic firing in dopaminergic neurons is sufficient for behavioral conditioning. Science (2009) 8.76
Neural substrates of awakening probed with optogenetic control of hypocretin neurons. Nature (2007) 8.22
An optical neural interface: in vivo control of rodent motor cortex with integrated fiberoptic and optogenetic technology. J Neural Eng (2007) 7.74
The Genomes of Oryza sativa: a history of duplications. PLoS Biol (2005) 7.67
Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia. Am J Hum Genet (2008) 7.33
A transcription activator-like effector toolbox for genome engineering. Nat Protoc (2012) 6.81
Targeting and readout strategies for fast optical neural control in vitro and in vivo. J Neurosci (2007) 6.28
Clinical findings in 111 cases of influenza A (H7N9) virus infection. N Engl J Med (2013) 5.38
Excitatory transmission from the amygdala to nucleus accumbens facilitates reward seeking. Nature (2011) 4.58
Mechanisms for human genomic rearrangements. Pathogenetics (2008) 4.54
A TALEN genome-editing system for generating human stem cell-based disease models. Cell Stem Cell (2012) 4.49
Systematic identification of C. elegans miRISC proteins, miRNAs, and mRNA targets by their interactions with GW182 proteins AIN-1 and AIN-2. Mol Cell (2007) 4.22
Epigenome-wide scans identify differentially methylated regions for age and age-related phenotypes in a healthy ageing population. PLoS Genet (2012) 4.05
Genetic control of individual differences in gene-specific methylation in human brain. Am J Hum Genet (2010) 3.91
Overexpression of long non-coding RNA HOTAIR predicts tumor recurrence in hepatocellular carcinoma patients following liver transplantation. Ann Surg Oncol (2011) 3.88
Rates of adult schizophrenia following prenatal exposure to the Chinese famine of 1959-1961. JAMA (2005) 3.83
Targeted optogenetic stimulation and recording of neurons in vivo using cell-type-specific expression of Channelrhodopsin-2. Nat Protoc (2010) 3.71
Global and local fMRI signals driven by neurons defined optogenetically by type and wiring. Nature (2010) 3.61
Comprehensive interrogation of natural TALE DNA-binding modules and transcriptional repressor domains. Nat Commun (2012) 3.60
Programmable repression and activation of bacterial gene expression using an engineered CRISPR-Cas system. Nucleic Acids Res (2013) 3.51
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nat Genet (2011) 3.40
Activation of specific interneurons improves V1 feature selectivity and visual perception. Nature (2012) 3.27
Long non-coding RNA MALAT-1 overexpression predicts tumor recurrence of hepatocellular carcinoma after liver transplantation. Med Oncol (2011) 3.24
Compromised humoral and delayed-type hypersensitivity responses in IL-23-deficient mice. J Immunol (2004) 3.23
Chromosome catastrophes involve replication mechanisms generating complex genomic rearrangements. Cell (2011) 3.03
Biological applications of gold nanoparticles. Chem Soc Rev (2008) 3.01
Genetic evidence supports demic diffusion of Han culture. Nature (2004) 2.92
China: the aging giant. J Am Geriatr Soc (2007) 2.89
Deep sequencing of the Camellia sinensis transcriptome revealed candidate genes for major metabolic pathways of tea-specific compounds. BMC Genomics (2011) 2.84
Crystal structure of the channelrhodopsin light-gated cation channel. Nature (2012) 2.83
CTCF is conserved from Drosophila to humans and confers enhancer blocking of the Fab-8 insulator. EMBO Rep (2005) 2.80
Assembly of endocytic machinery around individual influenza viruses during viral entry. Nat Struct Mol Biol (2004) 2.77
Common genetic variants modulate pathogen-sensing responses in human dendritic cells. Science (2014) 2.63
Efficient genome editing in plants using a CRISPR/Cas system. Cell Res (2013) 2.57
Identification of GATA3 as a breast cancer prognostic marker by global gene expression meta-analysis. Cancer Res (2005) 2.55
Complex rearrangements in patients with duplications of MECP2 can occur by fork stalling and template switching. Hum Mol Genet (2009) 2.50
SLAM family markers resolve functionally distinct subpopulations of hematopoietic stem cells and multipotent progenitors. Cell Stem Cell (2013) 2.47
Increased LIS1 expression affects human and mouse brain development. Nat Genet (2009) 2.45
Optogenetic interrogation of dopaminergic modulation of the multiple phases of reward-seeking behavior. J Neurosci (2011) 2.37
Transcription activator-like effector nucleases enable efficient plant genome engineering. Plant Physiol (2012) 2.36
Full-Length Genome Sequence of Porcine Deltacoronavirus Strain USA/IA/2014/8734. Genome Announc (2014) 2.30
Twist1-mediated adriamycin-induced epithelial-mesenchymal transition relates to multidrug resistance and invasive potential in breast cancer cells. Clin Cancer Res (2009) 2.28
An analysis of the indications for cesarean section in a teaching hospital in China. Eur J Obstet Gynecol Reprod Biol (2013) 2.26
Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension. PLoS Genet (2010) 2.24
Transposase-derived transcription factors regulate light signaling in Arabidopsis. Science (2007) 2.24
Unexpected consequences of a sudden and massive transposon amplification on rice gene expression. Nature (2009) 2.24
Role of SMAD and non-SMAD signals in the development of Th17 and regulatory T cells. J Immunol (2010) 2.20
Genome-wide association study identifies a susceptibility locus for schizophrenia in Han Chinese at 11p11.2. Nat Genet (2011) 2.13
Improved expression of halorhodopsin for light-induced silencing of neuronal activity. Brain Cell Biol (2008) 2.12
Iterative capped assembly: rapid and scalable synthesis of repeat-module DNA such as TAL effectors from individual monomers. Nucleic Acids Res (2012) 2.09
NIPA2 located in 15q11.2 is mutated in patients with childhood absence epilepsy. Hum Genet (2012) 2.08
Autism and other neuropsychiatric symptoms are prevalent in individuals with MeCP2 duplication syndrome. Ann Neurol (2009) 2.07
Pharmaceutical applications of hot-melt extrusion: part I. Drug Dev Ind Pharm (2007) 2.07
Transarticular screw and C1 hook fixation for os odontoideum with atlantoaxial dislocation. World Neurosurg (2011) 2.07
Minimally invasive pedicle screw fixation combined with percutaneous vertebroplasty in the surgical treatment of thoracolumbar osteoporosis fracture. J Neurosurg Spine (2013) 2.05
Dock180 and ELMO1 proteins cooperate to promote evolutionarily conserved Rac-dependent cell migration. J Biol Chem (2003) 2.04
Schizophrenia-related neural and behavioral phenotypes in transgenic mice expressing truncated Disc1. J Neurosci (2008) 2.04
Serum proprotein convertase subtilisin/kexin type 9 and cell surface low-density lipoprotein receptor: evidence for a reciprocal regulation. Circulation (2013) 2.03
A genome-wide association study identifies an osteoarthritis susceptibility locus on chromosome 7q22. Arthritis Rheum (2010) 2.02
Genome-wide scan for familial nasopharyngeal carcinoma reveals evidence of linkage to chromosome 4. Nat Genet (2002) 2.00
Upregulated MALAT-1 contributes to bladder cancer cell migration by inducing epithelial-to-mesenchymal transition. Mol Biosyst (2012) 2.00
Metabolic syndrome is associated with better nutritional status, but not with cardiovascular disease or all-cause mortality in patients on haemodialysis. Arch Cardiovasc Dis (2012) 1.99
Vitamin C: intravenous use by complementary and alternative medicine practitioners and adverse effects. PLoS One (2010) 1.92
The Plk1-dependent phosphoproteome of the early mitotic spindle. Mol Cell Proteomics (2010) 1.91
High-dose parenteral ascorbate enhanced chemosensitivity of ovarian cancer and reduced toxicity of chemotherapy. Sci Transl Med (2014) 1.91
Renal salt wasting and chronic dehydration in claudin-7-deficient mice. Am J Physiol Renal Physiol (2009) 1.90
MiR-21 induced angiogenesis through AKT and ERK activation and HIF-1α expression. PLoS One (2011) 1.90
Dissecting neural function using targeted genome engineering technologies. ACS Chem Neurosci (2012) 1.89
A quantitative fluorescence study of protein monolayer formation on colloidal nanoparticles. Nat Nanotechnol (2009) 1.85
Expression of lymphocytes and lymphocyte subsets in patients with severe acute respiratory syndrome. Clin Infect Dis (2003) 1.84
Plating osteosynthesis of mid-distal humeral shaft fractures: minimally invasive versus conventional open reduction technique. Int Orthop (2009) 1.82
Quality of Research Design Moderates Effects of Grade Retention on Achievement: A Meta-analytic, Multi-level Analysis. Educ Eval Policy Anal (2009) 1.78
Biotic and human vulnerability to projected changes in ocean biogeochemistry over the 21st century. PLoS Biol (2013) 1.78
MiR-145 directly targets p70S6K1 in cancer cells to inhibit tumor growth and angiogenesis. Nucleic Acids Res (2011) 1.77
Meta-analysis of genome-wide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22. Ann Rheum Dis (2010) 1.75
Environment. Building a "green" railway in China. Science (2007) 1.73
A role of matrix metalloproteinase-8 in atherosclerosis. Circ Res (2009) 1.72
Comparison of different cortical connectivity estimators for high-resolution EEG recordings. Hum Brain Mapp (2007) 1.71
Prevalence of diabetic retinopathy in rural China: the Handan Eye Study. Ophthalmology (2009) 1.70
RACK1 promotes breast carcinoma proliferation and invasion/metastasis in vitro and in vivo. Breast Cancer Res Treat (2009) 1.68
Olig2-positive progenitors in the embryonic spinal cord give rise not only to motoneurons and oligodendrocytes, but also to a subset of astrocytes and ependymal cells. Dev Biol (2006) 1.64
Reciprocal regulation of Akt and Oct4 promotes the self-renewal and survival of embryonal carcinoma cells. Mol Cell (2012) 1.63
Fabrication and Magnetic Properties of Fe65Co35-ZnO Nano-Granular Films. Nanoscale Res Lett (2010) 1.63
Transposition of the rice miniature inverted repeat transposable element mPing in Arabidopsis thaliana. Proc Natl Acad Sci U S A (2007) 1.63
Highly flexible silver nanowire electrodes for shape-memory polymer light-emitting diodes. Adv Mater (2010) 1.62