Published in J Mol Biol on July 12, 2007
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The small molecules AZD0530 and dasatinib inhibit dengue virus RNA replication via Fyn kinase. J Virol (2013) 0.92
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The C-terminal 18 Amino Acid Region of Dengue Virus NS5 Regulates its Subcellular Localization and Contains a Conserved Arginine Residue Essential for Infectious Virus Production. PLoS Pathog (2016) 0.77
The FDA-approved drug sofosbuvir inhibits Zika virus infection. Antiviral Res (2016) 0.76
The crystal structure of Zika virus NS5 reveals conserved drug targets. EMBO J (2017) 0.76
Antiviral activity of an N-allyl acridone against dengue virus. J Biomed Sci (2015) 0.75
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The conformational changes of Zika virus methyltransferase upon converting SAM to SAH. Oncotarget (2017) 0.75
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Crystal structure of the dengue virus RNA-dependent RNA polymerase catalytic domain at 1.85-angstrom resolution. J Virol (2007) 2.65
Assessing protein disorder and induced folding. Proteins (2006) 2.33
Crystal structure of the RNA polymerase domain of the West Nile virus non-structural protein 5. J Biol Chem (2007) 2.28
A practical overview of protein disorder prediction methods. Proteins (2006) 2.18
Discovery of an RNA virus 3'->5' exoribonuclease that is critically involved in coronavirus RNA synthesis. Proc Natl Acad Sci U S A (2006) 2.07
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HIV-1 and MLV Gag proteins are sufficient to recruit APOBEC3G into virus-like particles. Biochem Biophys Res Commun (2004) 1.80
Structural basis for the actin-binding function of missing-in-metastasis. Structure (2007) 1.79
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Towards the design of antiviral inhibitors against flaviviruses: the case for the multifunctional NS3 protein from Dengue virus as a target. Antiviral Res (2008) 1.41
The C-terminal domain of measles virus nucleoprotein belongs to the class of intrinsically disordered proteins that fold upon binding to their physiological partner. Virus Res (2004) 1.38
The flavivirus polymerase as a target for drug discovery. Antiviral Res (2008) 1.36
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Crystal structure and mechanistic determinants of SARS coronavirus nonstructural protein 15 define an endoribonuclease family. Proc Natl Acad Sci U S A (2006) 1.33
The crystal structures of Chikungunya and Venezuelan equine encephalitis virus nsP3 macro domains define a conserved adenosine binding pocket. J Virol (2009) 1.32
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Structural disorder within the replicative complex of measles virus: functional implications. Virology (2006) 1.25
Recognition of RNA cap in the Wesselsbron virus NS5 methyltransferase domain: implications for RNA-capping mechanisms in Flavivirus. J Mol Biol (2008) 1.25
The intrinsically disordered C-terminal domain of the measles virus nucleoprotein interacts with the C-terminal domain of the phosphoprotein via two distinct sites and remains predominantly unfolded. Protein Sci (2005) 1.20
The SARS-Coronavirus PLnc domain of nsp3 as a replication/transcription scaffolding protein. Virus Res (2008) 1.20
Structural basis for encapsidation of genomic RNA by La Crosse Orthobunyavirus nucleoprotein. Proc Natl Acad Sci U S A (2013) 1.19
Crystal structure and activity of Kunjin virus NS3 helicase; protease and helicase domain assembly in the full length NS3 protein. J Mol Biol (2007) 1.17
Practical application of bioinformatics by the multidisciplinary VIZIER consortium. Antiviral Res (2010) 1.17
Hsp72 recognizes a P binding motif in the measles virus N protein C-terminus. Virology (2005) 1.16
General catalytic deficiency of hepatitis C virus RNA polymerase with an S282T mutation and mutually exclusive resistance towards 2'-modified nucleotide analogues. Antimicrob Agents Chemother (2006) 1.15
Essential amino acids of the hantaan virus N protein in its interaction with RNA. J Virol (2005) 1.13
Structural bases for substrate recognition and activity in Meaban virus nucleoside-2'-O-methyltransferase. Protein Sci (2007) 1.13
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Cooperative and specific binding of Vif to the 5' region of HIV-1 genomic RNA. J Mol Biol (2005) 1.13
A relaxed discrimination of 2'-O-methyl-GTP relative to GTP between de novo and Elongative RNA synthesis by the hepatitis C RNA-dependent RNA polymerase NS5B. J Biol Chem (2004) 1.13
Processing of alpha4 integrin by the proprotein convertases: histidine at position P6 regulates cleavage. Biochem J (2003) 1.10
Measles virus (MV) nucleoprotein binds to a novel cell surface receptor distinct from FcgammaRII via its C-terminal domain: role in MV-induced immunosuppression. J Virol (2003) 1.10
Virtual screening and bioassay study of novel inhibitors for dengue virus mRNA cap (nucleoside-2'O)-methyltransferase. Bioorg Med Chem (2007) 1.09
The molecular mechanism of multidrug resistance by the Q151M human immunodeficiency virus type 1 reverse transcriptase and its suppression using alpha-boranophosphate nucleotide analogues. J Biol Chem (2002) 1.09
Predicting protein disorder and induced folding: from theoretical principles to practical applications. Curr Protein Pept Sci (2007) 1.07
The N-terminal domain of the phosphoprotein of Morbilliviruses belongs to the natively unfolded class of proteins. Virology (2002) 1.07
Crystal structure of the actin-binding domain of alpha-actinin 1: evaluating two competing actin-binding models. J Struct Biol (2006) 1.03
MeDor: a metaserver for predicting protein disorder. BMC Genomics (2008) 1.03
Structural and functional characterization of sapovirus RNA-dependent RNA polymerase. J Virol (2006) 1.03
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The thiazolobenzimidazole TBZE-029 inhibits enterovirus replication by targeting a short region immediately downstream from motif C in the nonstructural protein 2C. J Virol (2008) 1.02
Structural genomics of the SARS coronavirus: cloning, expression, crystallization and preliminary crystallographic study of the Nsp9 protein. Acta Crystallogr D Biol Crystallogr (2003) 1.01
Actin polymerization in differentiated vascular smooth muscle cells requires vasodilator-stimulated phosphoprotein. Am J Physiol Cell Physiol (2009) 1.01
Flavivirus NS3 and NS5 proteins interaction network: a high-throughput yeast two-hybrid screen. BMC Microbiol (2011) 1.01
Flaviviral methyltransferase/RNA interaction: structural basis for enzyme inhibition. Antiviral Res (2009) 1.00
De novo initiation of RNA synthesis by the arterivirus RNA-dependent RNA polymerase. J Virol (2007) 0.98
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Synthesis, in vitro antiviral evaluation, and stability studies of novel alpha-borano-nucleotide analogues of 9-[2-(phosphonomethoxy)ethyl]adenine and (R)-9-[2-(phosphonomethoxy)propyl]adenine. J Med Chem (2006) 0.97