Published in J Hered on August 16, 2007
Guiding the optimal translation of new cancer treatments from canine to human cancer patients. Clin Cancer Res (2009) 1.10
Influence of genetic background on tumor karyotypes: evidence for breed-associated cytogenetic aberrations in canine appendicular osteosarcoma. Chromosome Res (2009) 1.07
'Putting our heads together': insights into genomic conservation between human and canine intracranial tumors. J Neurooncol (2009) 1.01
A genome assembly-integrated dog 1 Mb BAC microarray: a cytogenetic resource for canine cancer studies and comparative genomic analysis. Cytogenet Genome Res (2008) 0.93
Anchoring the dog to its relatives reveals new evolutionary breakpoints across 11 species of the Canidae and provides new clues for the role of B chromosomes. Chromosome Res (2011) 0.89
Canine cytogenetics--from band to basepair. Cytogenet Genome Res (2008) 0.88
Construction and application of a zebrafish array comparative genomic hybridization platform. Genes Chromosomes Cancer (2009) 0.87
Genome aberrations in canine mammary carcinomas and their detection in cell-free plasma DNA. PLoS One (2013) 0.84
Tackling the characterization of canine chromosomal breakpoints with an integrated in-situ/in-silico approach: the canine PAR and PAB. Chromosome Res (2008) 0.83
Generation and characterization of novel canine malignant mast cell line CL1. Vet Immunol Immunopathol (2008) 0.78
Establishment and characterization of a new cell line of canine inflammatory mammary cancer: IPC-366. PLoS One (2015) 0.78
Chromosomal mapping of canine-derived BAC clones to the red fox and American mink genomes. J Hered (2009) 0.77
Molecular characterization of canine BCR-ABL-positive chronic myelomonocytic leukemia before and after chemotherapy. Vet Clin Pathol (2013) 0.76
A novel canine kidney cell line model for the evaluation of neoplastic development: karyotype evolution associated with spontaneous immortalization and tumorigenicity. Chromosome Res (2015) 0.75
Microarray-based cytogenetic profiling reveals recurrent and subtype-associated genomic copy number aberrations in feline sarcomas. Chromosome Res (2009) 0.75
Initial sequencing and comparative analysis of the mouse genome. Nature (2002) 96.15
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature (2007) 75.09
Full-length transcriptome assembly from RNA-Seq data without a reference genome. Nat Biotechnol (2011) 53.86
Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals. Nature (2005) 31.60
Genome sequence, comparative analysis and haplotype structure of the domestic dog. Nature (2005) 23.04
Genomic maps and comparative analysis of histone modifications in human and mouse. Cell (2005) 18.96
Evolution of genes and genomes on the Drosophila phylogeny. Nature (2007) 18.01
Whole-genome sequence assembly for mammalian genomes: Arachne 2. Genome Res (2003) 12.30
Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls. Nature (2010) 12.27
Genome duplication in the teleost fish Tetraodon nigroviridis reveals the early vertebrate proto-karyotype. Nature (2004) 11.03
Distinguishing protein-coding and noncoding genes in the human genome. Proc Natl Acad Sci U S A (2007) 8.00
A novel CpG island set identifies tissue-specific methylation at developmental gene loci. PLoS Biol (2008) 7.95
Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences. Nature (2007) 7.91
Analyses of deep mammalian sequence alignments and constraint predictions for 1% of the human genome. Genome Res (2007) 7.05
Identification and classification of conserved RNA secondary structures in the human genome. PLoS Comput Biol (2006) 6.73
The mosaic structure of variation in the laboratory mouse genome. Nature (2002) 6.54
Clinical and biological implications of driver mutations in myelodysplastic syndromes. Blood (2013) 6.50
Genome sequence and analysis of the Irish potato famine pathogen Phytophthora infestans. Nature (2009) 6.44
28-way vertebrate alignment and conservation track in the UCSC Genome Browser. Genome Res (2007) 6.42
Efficient mapping of mendelian traits in dogs through genome-wide association. Nat Genet (2007) 5.99
The landscape of histone modifications across 1% of the human genome in five human cell lines. Genome Res (2007) 5.67
A composite of multiple signals distinguishes causal variants in regions of positive selection. Science (2010) 5.61
Accurate and reliable high-throughput detection of copy number variation in the human genome. Genome Res (2006) 5.50
Negotiating for change. The healthcare manager as catalyst for evidence-based practice: changing the healthcare environment and sharing experience. Healthc Pap (2003) 5.49
Whole-genome resequencing reveals loci under selection during chicken domestication. Nature (2010) 5.48
Lineage-specific biology revealed by a finished genome assembly of the mouse. PLoS Biol (2009) 5.45
The genomic basis of adaptive evolution in threespine sticklebacks. Nature (2012) 5.20
Systematic discovery of regulatory motifs in conserved regions of the human genome, including thousands of CTCF insulator sites. Proc Natl Acad Sci U S A (2007) 4.91
Initial sequence and comparative analysis of the cat genome. Genome Res (2007) 4.67
An initial strategy for the systematic identification of functional elements in the human genome by low-redundancy comparative sequencing. Proc Natl Acad Sci U S A (2005) 4.38
Barriers to participation in clinical trials of cancer: a meta-analysis and systematic review of patient-reported factors. Lancet Oncol (2006) 4.32
Sequencing the nuclear genome of the extinct woolly mammoth. Nature (2008) 4.31
Epigenome-wide scans identify differentially methylated regions for age and age-related phenotypes in a healthy ageing population. PLoS Genet (2012) 4.05
Genetics of gene expression in primary immune cells identifies cell type-specific master regulators and roles of HLA alleles. Nat Genet (2012) 3.77
Randomized phase III trial comparing irinotecan/cisplatin with etoposide/cisplatin in patients with previously untreated extensive-stage disease small-cell lung cancer. J Clin Oncol (2006) 3.71
A HaemAtlas: characterizing gene expression in differentiated human blood cells. Blood (2009) 3.63
The genomic signature of dog domestication reveals adaptation to a starch-rich diet. Nature (2013) 3.61
FRT-seq: amplification-free, strand-specific transcriptome sequencing. Nat Methods (2010) 3.55
The genome of the green anole lizard and a comparative analysis with birds and mammals. Nature (2011) 3.32
The African coelacanth genome provides insights into tetrapod evolution. Nature (2013) 2.78
Assembly of polymorphic genomes: algorithms and application to Ciona savignyi. Genome Res (2005) 2.69
Genomic and epigenetic evidence for oxytocin receptor deficiency in autism. BMC Med (2009) 2.60
Identifying recent adaptations in large-scale genomic data. Cell (2013) 2.57
Genome-wide synteny through highly sensitive sequence alignment: Satsuma. Bioinformatics (2010) 2.56
Outcome of ANCA-associated renal vasculitis: a 5-year retrospective study. Am J Kidney Dis (2003) 2.40
Genomic targets of nuclear estrogen receptors. Mol Endocrinol (2004) 2.34
Duplication of FGF3, FGF4, FGF19 and ORAOV1 causes hair ridge and predisposition to dermoid sinus in Ridgeback dogs. Nat Genet (2007) 2.33
PiggyBac transposon mutagenesis: a tool for cancer gene discovery in mice. Science (2010) 2.31
Significant predictive factors for prognosis of primary upper urinary tract cancer after radical nephroureterectomy in Taiwanese patients. Eur Urol (2008) 2.31
Gene expression profiles of CD34+ cells in myelodysplastic syndromes: involvement of interferon-stimulated genes and correlation to FAB subtype and karyotype. Blood (2006) 2.29
Randomized phase IIB trial of BLP25 liposome vaccine in stage IIIB and IV non-small-cell lung cancer. J Clin Oncol (2005) 2.25
Identification of genomic regions associated with phenotypic variation between dog breeds using selection mapping. PLoS Genet (2011) 2.24
A cis-acting regulatory mutation causes premature hair graying and susceptibility to melanoma in the horse. Nat Genet (2008) 2.13
Leader of the pack: gene mapping in dogs and other model organisms. Nat Rev Genet (2008) 2.12
Three periods of regulatory innovation during vertebrate evolution. Science (2011) 2.09
The dog as a cancer model. Nat Biotechnol (2006) 2.08
A mutation in hairless dogs implicates FOXI3 in ectodermal development. Science (2008) 2.06
Rethinking dog domestication by integrating genetics, archeology, and biogeography. Proc Natl Acad Sci U S A (2012) 1.78
Mutations in KCND3 cause spinocerebellar ataxia type 22. Ann Neurol (2012) 1.76
Genome-wide association analysis reveals a SOD1 mutation in canine degenerative myelopathy that resembles amyotrophic lateral sclerosis. Proc Natl Acad Sci U S A (2009) 1.72
Mutant nucleophosmin and cooperating pathways drive leukemia initiation and progression in mice. Nat Genet (2011) 1.71
Genome-wide analysis in German shepherd dogs reveals association of a locus on CFA 27 with atopic dermatitis. PLoS Genet (2013) 1.69
Mutation discovery in mice by whole exome sequencing. Genome Biol (2011) 1.69
A missense mutation in the SERPINH1 gene in Dachshunds with osteogenesis imperfecta. PLoS Genet (2009) 1.68
Identification and functional validation of the novel antimalarial resistance locus PF10_0355 in Plasmodium falciparum. PLoS Genet (2011) 1.68
A high density SNP array for the domestic horse and extant Perissodactyla: utility for association mapping, genetic diversity, and phylogeny studies. PLoS Genet (2012) 1.66
A mutation in the canine BHD gene is associated with hereditary multifocal renal cystadenocarcinoma and nodular dermatofibrosis in the German Shepherd dog. Hum Mol Genet (2003) 1.66
Death of PRDM9 coincides with stabilization of the recombination landscape in the dog genome. Genome Res (2011) 1.62
ZBED6, a novel transcription factor derived from a domesticated DNA transposon regulates IGF2 expression and muscle growth. PLoS Biol (2009) 1.61
Increased risk of diabetes and polychlorinated biphenyls and dioxins: a 24-year follow-up study of the Yucheng cohort. Diabetes Care (2008) 1.58
Mutations causing medullary cystic kidney disease type 1 lie in a large VNTR in MUC1 missed by massively parallel sequencing. Nat Genet (2013) 1.52
Genome-wide association mapping identifies multiple loci for a canine SLE-related disease complex. Nat Genet (2010) 1.49
Metabolomic markers reveal novel pathways of ageing and early development in human populations. Int J Epidemiol (2013) 1.48
A novel unstable duplication upstream of HAS2 predisposes to a breed-defining skin phenotype and a periodic fever syndrome in Chinese Shar-Pei dogs. PLoS Genet (2011) 1.45
Origins and evolution of a transmissible cancer. Evolution (2009) 1.43
Genome-wide association identifies a deletion in the 3' untranslated region of striatin in a canine model of arrhythmogenic right ventricular cardiomyopathy. Hum Genet (2010) 1.43
A deletion in nephronophthisis 4 (NPHP4) is associated with recessive cone-rod dystrophy in standard wire-haired dachshund. Genome Res (2008) 1.42
Distinct cytokine-driven responses of activated blood gammadelta T cells: insights into unconventional T cell pleiotropy. J Immunol (2007) 1.42
Integrated multiomics approach identifies calcium and integrin-binding protein-2 as a novel gene for pulse wave velocity. J Hypertens (2016) 1.41
Spreading of mammalian DNA-damage response factors studied by ChIP-chip at damaged telomeres. EMBO J (2007) 1.38
The dog and rat olfactory receptor repertoires. Genome Biol (2005) 1.37
Origins of shared genetic variation in African cichlids. Mol Biol Evol (2012) 1.35
Butyrate mediates decrease of histone acetylation centered on transcription start sites and down-regulation of associated genes. Genome Res (2007) 1.35