Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
Toxin B is essential for virulence of Clostridium difficile.
|
Nature
|
2009
|
5.49
|
2
|
Skewed genomic variability in strains of the toxigenic bacterial pathogen, Clostridium perfringens.
|
Genome Res
|
2006
|
2.84
|
3
|
Genome reduction in Leptospira borgpetersenii reflects limited transmission potential.
|
Proc Natl Acad Sci U S A
|
2006
|
2.71
|
4
|
Construction and analysis of chromosomal Clostridium difficile mutants.
|
Mol Microbiol
|
2006
|
2.65
|
5
|
Genome sequence of the saprophyte Leptospira biflexa provides insights into the evolution of Leptospira and the pathogenesis of leptospirosis.
|
PLoS One
|
2008
|
2.35
|
6
|
NetB, a new toxin that is associated with avian necrotic enteritis caused by Clostridium perfringens.
|
PLoS Pathog
|
2008
|
2.23
|
7
|
Construction of an alpha toxin gene knockout mutant of Clostridium perfringens type A by use of a mobile group II intron.
|
Appl Environ Microbiol
|
2005
|
2.01
|
8
|
Beta toxin is essential for the intestinal virulence of Clostridium perfringens type C disease isolate CN3685 in a rabbit ileal loop model.
|
Mol Microbiol
|
2008
|
1.78
|
9
|
Alpha-toxin of Clostridium perfringens is not an essential virulence factor in necrotic enteritis in chickens.
|
Infect Immun
|
2006
|
1.62
|
10
|
Environmental response and autoregulation of Clostridium difficile TxeR, a sigma factor for toxin gene expression.
|
J Bacteriol
|
2002
|
1.53
|
11
|
Revised nomenclature for transposable genetic elements.
|
Plasmid
|
2008
|
1.50
|
12
|
Epsilon-toxin is required for most Clostridium perfringens type D vegetative culture supernatants to cause lethality in the mouse intravenous injection model.
|
Infect Immun
|
2005
|
1.49
|
13
|
Dissecting the contributions of Clostridium perfringens type C toxins to lethality in the mouse intravenous injection model.
|
Infect Immun
|
2006
|
1.49
|
14
|
Rethinking our understanding of the pathogenesis of necrotic enteritis in chickens.
|
Trends Microbiol
|
2008
|
1.39
|
15
|
Functional identification of conjugation and replication regions of the tetracycline resistance plasmid pCW3 from Clostridium perfringens.
|
J Bacteriol
|
2006
|
1.39
|
16
|
The role of toxin A and toxin B in Clostridium difficile-associated disease: Past and present perspectives.
|
Gut Microbes
|
2010
|
1.37
|
17
|
The alpha-toxin of Clostridium septicum is essential for virulence.
|
Mol Microbiol
|
2005
|
1.32
|
18
|
Binary toxin production in Clostridium difficile is regulated by CdtR, a LytTR family response regulator.
|
J Bacteriol
|
2007
|
1.29
|
19
|
Revised nomenclature of Clostridium difficile toxins and associated genes.
|
J Med Microbiol
|
2005
|
1.28
|
20
|
The anti-sigma factor TcdC modulates hypervirulence in an epidemic BI/NAP1/027 clinical isolate of Clostridium difficile.
|
PLoS Pathog
|
2011
|
1.28
|
21
|
Genome sequence and identification of candidate vaccine antigens from the animal pathogen Dichelobacter nodosus.
|
Nat Biotechnol
|
2007
|
1.25
|
22
|
The VirSR two-component signal transduction system regulates NetB toxin production in Clostridium perfringens.
|
Infect Immun
|
2010
|
1.20
|
23
|
TcpA, an FtsK/SpoIIIE homolog, is essential for transfer of the conjugative plasmid pCW3 in Clostridium perfringens.
|
J Bacteriol
|
2007
|
1.19
|
24
|
Epsilon-toxin plasmids of Clostridium perfringens type D are conjugative.
|
J Bacteriol
|
2007
|
1.16
|
25
|
Both epsilon-toxin and beta-toxin are important for the lethal properties of Clostridium perfringens type B isolates in the mouse intravenous injection model.
|
Infect Immun
|
2007
|
1.15
|
26
|
The role of toxin A and toxin B in the virulence of Clostridium difficile.
|
Trends Microbiol
|
2011
|
1.14
|
27
|
The spatial organization of the VirR boxes is critical for VirR-mediated expression of the perfringolysin O gene, pfoA, from Clostridium perfringens.
|
J Bacteriol
|
2004
|
1.11
|
28
|
The subtilisin-like protease AprV2 is required for virulence and uses a novel disulphide-tethered exosite to bind substrates.
|
PLoS Pathog
|
2010
|
1.10
|
29
|
Development and application of new mouse models to study the pathogenesis of Clostridium perfringens type C Enterotoxemias.
|
Infect Immun
|
2009
|
1.10
|
30
|
Programmed cellular necrosis mediated by the pore-forming alpha-toxin from Clostridium septicum.
|
PLoS Pathog
|
2009
|
1.09
|
31
|
Molecular and cellular basis of microvascular perfusion deficits induced by Clostridium perfringens and Clostridium septicum.
|
PLoS Pathog
|
2008
|
1.07
|
32
|
The conjugation protein TcpC from Clostridium perfringens is structurally related to the type IV secretion system protein VirB8 from Gram-negative bacteria.
|
Mol Microbiol
|
2011
|
1.07
|
33
|
The FxRxHrS motif: a conserved region essential for DNA binding of the VirR response regulator from Clostridium perfringens.
|
J Mol Biol
|
2002
|
1.07
|
34
|
Toxin plasmids of Clostridium perfringens.
|
Microbiol Mol Biol Rev
|
2013
|
1.07
|
35
|
Towards an understanding of the role of Clostridium perfringens toxins in human and animal disease.
|
Future Microbiol
|
2014
|
1.07
|
36
|
Influence of gastric acid on susceptibility to infection with ingested bacterial pathogens.
|
Infect Immun
|
2007
|
1.07
|
37
|
Association between avian necrotic enteritis and Clostridium perfringens strains expressing NetB toxin.
|
Vet Res
|
2009
|
1.05
|
38
|
The NanI and NanJ sialidases of Clostridium perfringens are not essential for virulence.
|
Infect Immun
|
2009
|
1.02
|
39
|
Type IV fimbrial biogenesis is required for protease secretion and natural transformation in Dichelobacter nodosus.
|
J Bacteriol
|
2007
|
1.02
|
40
|
The SKHR motif is required for biological function of the VirR response regulator from Clostridium perfringens.
|
J Bacteriol
|
2003
|
1.00
|
41
|
Spo0A differentially regulates toxin production in evolutionarily diverse strains of Clostridium difficile.
|
PLoS One
|
2013
|
0.99
|
42
|
Twitching motility is essential for virulence in Dichelobacter nodosus.
|
J Bacteriol
|
2008
|
0.99
|
43
|
The pathogenesis of ovine footrot.
|
Vet Microbiol
|
2011
|
0.98
|
44
|
Necrotic enteritis-derived Clostridium perfringens strain with three closely related independently conjugative toxin and antibiotic resistance plasmids.
|
MBio
|
2011
|
0.98
|
45
|
Functional characterization and localization of the TcpH conjugation protein from Clostridium perfringens.
|
J Bacteriol
|
2008
|
0.98
|
46
|
Functional analysis of the VirSR phosphorelay from Clostridium perfringens.
|
PLoS One
|
2009
|
0.98
|
47
|
Ecf, an alternative sigma factor from Neisseria gonorrhoeae, controls expression of msrAB, which encodes methionine sulfoxide reductase.
|
J Bacteriol
|
2006
|
0.97
|
48
|
Detection and diversity of a putative novel heterogeneous polymorphic proline-glycine repeat (Pgr) protein in the footrot pathogen Dichelobacter nodosus.
|
Vet Microbiol
|
2010
|
0.97
|
49
|
The large resolvase TnpX is the only transposon-encoded protein required for transposition of the Tn4451/3 family of integrative mobilizable elements.
|
Mol Microbiol
|
2004
|
0.96
|
50
|
TcsL is an essential virulence factor in Clostridium sordellii ATCC 9714.
|
Infect Immun
|
2011
|
0.95
|
51
|
Structural and functional analysis of the pore-forming toxin NetB from Clostridium perfringens.
|
MBio
|
2013
|
0.95
|
52
|
Development and application of an oral challenge mouse model for studying Clostridium perfringens type D infection.
|
Infect Immun
|
2007
|
0.94
|
53
|
DNA binding properties of TnpX indicate that different synapses are formed in the excision and integration of the Tn4451 family.
|
Mol Microbiol
|
2004
|
0.94
|
54
|
Regulation of virulence by the RevR response regulator in Clostridium perfringens.
|
Infect Immun
|
2011
|
0.93
|
55
|
The putative coupling protein TcpA interacts with other pCW3-encoded proteins to form an essential part of the conjugation complex.
|
J Bacteriol
|
2009
|
0.93
|
56
|
Epsilon-toxin production by Clostridium perfringens type D strain CN3718 is dependent upon the agr operon but not the VirS/VirR two-component regulatory system.
|
MBio
|
2011
|
0.92
|
57
|
Comparison of the RpoH-dependent regulon and general stress response in Neisseria gonorrhoeae.
|
J Bacteriol
|
2006
|
0.92
|
58
|
Pore-forming activity of alpha-toxin is essential for clostridium septicum-mediated myonecrosis.
|
Infect Immun
|
2009
|
0.89
|
59
|
The peptidoglycan hydrolase TcpG is required for efficient conjugative transfer of pCW3 in Clostridium perfringens.
|
Plasmid
|
2012
|
0.89
|
60
|
Highly conserved alpha-toxin sequences of avian isolates of Clostridium perfringens.
|
J Clin Microbiol
|
2004
|
0.88
|
61
|
Identification of the structural and functional domains of the large serine recombinase TnpX from Clostridium perfringens.
|
J Biol Chem
|
2004
|
0.88
|
62
|
TcdB or not TcdB: a tale of two Clostridium difficile toxins.
|
Future Microbiol
|
2011
|
0.88
|
63
|
Identification of essential residues in the Erm(B) rRNA methyltransferase of Clostridium perfringens.
|
Antimicrob Agents Chemother
|
2002
|
0.88
|
64
|
Vaccination with recombinant NetB toxin partially protects broiler chickens from necrotic enteritis.
|
Vet Res
|
2013
|
0.87
|
65
|
NetB, a pore-forming toxin from necrotic enteritis strains of Clostridium perfringens.
|
Toxins (Basel)
|
2010
|
0.87
|
66
|
Two distinct regions of the large serine recombinase TnpX are required for DNA binding and biological function.
|
Mol Microbiol
|
2006
|
0.87
|
67
|
S1 pocket of a bacterially derived subtilisin-like protease underpins effective tissue destruction.
|
J Biol Chem
|
2011
|
0.87
|
68
|
Identification of a Dichelobacter nodosus ferric uptake regulator and determination of its regulatory targets.
|
J Bacteriol
|
2005
|
0.86
|
69
|
Chloramphenicol-resistant Neisseria meningitidis containing catP isolated in Australia.
|
J Antimicrob Chemother
|
2003
|
0.86
|
70
|
Cross-complementation of Clostridium perfringens PLC and Clostridium septicum alpha-toxin mutants reveals PLC is sufficient to mediate gas gangrene.
|
Microbes Infect
|
2009
|
0.84
|
71
|
Regulation of sialidase production in Clostridium perfringens by the orphan sensor histidine kinase ReeS.
|
PLoS One
|
2013
|
0.84
|
72
|
tISCpe8, an IS1595-family lincomycin resistance element located on a conjugative plasmid in Clostridium perfringens.
|
J Bacteriol
|
2009
|
0.84
|
73
|
The cysteine protease α-clostripain is not essential for the pathogenesis of Clostridium perfringens-mediated myonecrosis.
|
PLoS One
|
2011
|
0.84
|
74
|
Perfringolysin O expression in Clostridium perfringens is independent of the upstream pfoR gene.
|
J Bacteriol
|
2002
|
0.83
|
75
|
Transformation-mediated serogroup conversion of Dichelobacter nodosus.
|
Vet Microbiol
|
2003
|
0.82
|
76
|
Maternal immunization with vaccines containing recombinant NetB toxin partially protects progeny chickens from necrotic enteritis.
|
Vet Res
|
2013
|
0.82
|
77
|
Virulence Plasmids of Spore-Forming Bacteria.
|
Microbiol Spectr
|
2014
|
0.81
|
78
|
The Clostridium perfringens TetA(P) efflux protein contains a functional variant of the Motif A region found in major facilitator superfamily transport proteins.
|
Microbiology
|
2004
|
0.81
|
79
|
Regulation of type IV fimbrial biogenesis in Dichelobacter nodosus.
|
J Bacteriol
|
2006
|
0.80
|
80
|
The AprV5 subtilase is required for the optimal processing of all three extracellular serine proteases from Dichelobacter nodosus.
|
PLoS One
|
2012
|
0.80
|
81
|
Crystallization of the virulent and benign subtilisin-like proteases from the ovine footrot pathogen Dichelobacter nodosus.
|
Acta Crystallogr Sect F Struct Biol Cryst Commun
|
2010
|
0.79
|
82
|
Novel use of tryptose sulfite cycloserine egg yolk agar for isolation of Clostridium perfringens during an outbreak of necrotizing enterocolitis in a neonatal unit.
|
J Clin Microbiol
|
2010
|
0.78
|
83
|
Utility of the clostridial site-specific recombinase TnpX to clone toxic-product-encoding genes and selectively remove genomic DNA fragments.
|
Appl Environ Microbiol
|
2014
|
0.78
|
84
|
Isolation of the Bacteriophage DinoHI from Dichelobacter nodosus and its Interactions with other Integrated Genetic Elements.
|
Open Microbiol J
|
2008
|
0.76
|
85
|
Methods for gene cloning and targeted mutagenesis.
|
Methods Mol Biol
|
2010
|
0.76
|
86
|
Infectious disease: Listeria does it again.
|
Nature
|
2010
|
0.75
|
87
|
Identification of a leukotoxin sequence from Fusobacterium equinum.
|
Vet Microbiol
|
2008
|
0.75
|
88
|
Solution structure and DNA binding of the catalytic domain of the large serine resolvase TnpX.
|
J Mol Recognit
|
2015
|
0.75
|