Julian I Rood

Author PubWeight™ 100.42‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Toxin B is essential for virulence of Clostridium difficile. Nature 2009 5.49
2 Skewed genomic variability in strains of the toxigenic bacterial pathogen, Clostridium perfringens. Genome Res 2006 2.84
3 Genome reduction in Leptospira borgpetersenii reflects limited transmission potential. Proc Natl Acad Sci U S A 2006 2.71
4 Construction and analysis of chromosomal Clostridium difficile mutants. Mol Microbiol 2006 2.65
5 Genome sequence of the saprophyte Leptospira biflexa provides insights into the evolution of Leptospira and the pathogenesis of leptospirosis. PLoS One 2008 2.35
6 NetB, a new toxin that is associated with avian necrotic enteritis caused by Clostridium perfringens. PLoS Pathog 2008 2.23
7 Construction of an alpha toxin gene knockout mutant of Clostridium perfringens type A by use of a mobile group II intron. Appl Environ Microbiol 2005 2.01
8 Beta toxin is essential for the intestinal virulence of Clostridium perfringens type C disease isolate CN3685 in a rabbit ileal loop model. Mol Microbiol 2008 1.78
9 Alpha-toxin of Clostridium perfringens is not an essential virulence factor in necrotic enteritis in chickens. Infect Immun 2006 1.62
10 Environmental response and autoregulation of Clostridium difficile TxeR, a sigma factor for toxin gene expression. J Bacteriol 2002 1.53
11 Revised nomenclature for transposable genetic elements. Plasmid 2008 1.50
12 Epsilon-toxin is required for most Clostridium perfringens type D vegetative culture supernatants to cause lethality in the mouse intravenous injection model. Infect Immun 2005 1.49
13 Dissecting the contributions of Clostridium perfringens type C toxins to lethality in the mouse intravenous injection model. Infect Immun 2006 1.49
14 Rethinking our understanding of the pathogenesis of necrotic enteritis in chickens. Trends Microbiol 2008 1.39
15 Functional identification of conjugation and replication regions of the tetracycline resistance plasmid pCW3 from Clostridium perfringens. J Bacteriol 2006 1.39
16 The role of toxin A and toxin B in Clostridium difficile-associated disease: Past and present perspectives. Gut Microbes 2010 1.37
17 The alpha-toxin of Clostridium septicum is essential for virulence. Mol Microbiol 2005 1.32
18 Binary toxin production in Clostridium difficile is regulated by CdtR, a LytTR family response regulator. J Bacteriol 2007 1.29
19 Revised nomenclature of Clostridium difficile toxins and associated genes. J Med Microbiol 2005 1.28
20 The anti-sigma factor TcdC modulates hypervirulence in an epidemic BI/NAP1/027 clinical isolate of Clostridium difficile. PLoS Pathog 2011 1.28
21 Genome sequence and identification of candidate vaccine antigens from the animal pathogen Dichelobacter nodosus. Nat Biotechnol 2007 1.25
22 The VirSR two-component signal transduction system regulates NetB toxin production in Clostridium perfringens. Infect Immun 2010 1.20
23 TcpA, an FtsK/SpoIIIE homolog, is essential for transfer of the conjugative plasmid pCW3 in Clostridium perfringens. J Bacteriol 2007 1.19
24 Epsilon-toxin plasmids of Clostridium perfringens type D are conjugative. J Bacteriol 2007 1.16
25 Both epsilon-toxin and beta-toxin are important for the lethal properties of Clostridium perfringens type B isolates in the mouse intravenous injection model. Infect Immun 2007 1.15
26 The role of toxin A and toxin B in the virulence of Clostridium difficile. Trends Microbiol 2011 1.14
27 The spatial organization of the VirR boxes is critical for VirR-mediated expression of the perfringolysin O gene, pfoA, from Clostridium perfringens. J Bacteriol 2004 1.11
28 The subtilisin-like protease AprV2 is required for virulence and uses a novel disulphide-tethered exosite to bind substrates. PLoS Pathog 2010 1.10
29 Development and application of new mouse models to study the pathogenesis of Clostridium perfringens type C Enterotoxemias. Infect Immun 2009 1.10
30 Programmed cellular necrosis mediated by the pore-forming alpha-toxin from Clostridium septicum. PLoS Pathog 2009 1.09
31 Molecular and cellular basis of microvascular perfusion deficits induced by Clostridium perfringens and Clostridium septicum. PLoS Pathog 2008 1.07
32 The conjugation protein TcpC from Clostridium perfringens is structurally related to the type IV secretion system protein VirB8 from Gram-negative bacteria. Mol Microbiol 2011 1.07
33 The FxRxHrS motif: a conserved region essential for DNA binding of the VirR response regulator from Clostridium perfringens. J Mol Biol 2002 1.07
34 Toxin plasmids of Clostridium perfringens. Microbiol Mol Biol Rev 2013 1.07
35 Towards an understanding of the role of Clostridium perfringens toxins in human and animal disease. Future Microbiol 2014 1.07
36 Influence of gastric acid on susceptibility to infection with ingested bacterial pathogens. Infect Immun 2007 1.07
37 Association between avian necrotic enteritis and Clostridium perfringens strains expressing NetB toxin. Vet Res 2009 1.05
38 The NanI and NanJ sialidases of Clostridium perfringens are not essential for virulence. Infect Immun 2009 1.02
39 Type IV fimbrial biogenesis is required for protease secretion and natural transformation in Dichelobacter nodosus. J Bacteriol 2007 1.02
40 The SKHR motif is required for biological function of the VirR response regulator from Clostridium perfringens. J Bacteriol 2003 1.00
41 Spo0A differentially regulates toxin production in evolutionarily diverse strains of Clostridium difficile. PLoS One 2013 0.99
42 Twitching motility is essential for virulence in Dichelobacter nodosus. J Bacteriol 2008 0.99
43 The pathogenesis of ovine footrot. Vet Microbiol 2011 0.98
44 Necrotic enteritis-derived Clostridium perfringens strain with three closely related independently conjugative toxin and antibiotic resistance plasmids. MBio 2011 0.98
45 Functional characterization and localization of the TcpH conjugation protein from Clostridium perfringens. J Bacteriol 2008 0.98
46 Functional analysis of the VirSR phosphorelay from Clostridium perfringens. PLoS One 2009 0.98
47 Ecf, an alternative sigma factor from Neisseria gonorrhoeae, controls expression of msrAB, which encodes methionine sulfoxide reductase. J Bacteriol 2006 0.97
48 Detection and diversity of a putative novel heterogeneous polymorphic proline-glycine repeat (Pgr) protein in the footrot pathogen Dichelobacter nodosus. Vet Microbiol 2010 0.97
49 The large resolvase TnpX is the only transposon-encoded protein required for transposition of the Tn4451/3 family of integrative mobilizable elements. Mol Microbiol 2004 0.96
50 TcsL is an essential virulence factor in Clostridium sordellii ATCC 9714. Infect Immun 2011 0.95
51 Structural and functional analysis of the pore-forming toxin NetB from Clostridium perfringens. MBio 2013 0.95
52 Development and application of an oral challenge mouse model for studying Clostridium perfringens type D infection. Infect Immun 2007 0.94
53 DNA binding properties of TnpX indicate that different synapses are formed in the excision and integration of the Tn4451 family. Mol Microbiol 2004 0.94
54 Regulation of virulence by the RevR response regulator in Clostridium perfringens. Infect Immun 2011 0.93
55 The putative coupling protein TcpA interacts with other pCW3-encoded proteins to form an essential part of the conjugation complex. J Bacteriol 2009 0.93
56 Epsilon-toxin production by Clostridium perfringens type D strain CN3718 is dependent upon the agr operon but not the VirS/VirR two-component regulatory system. MBio 2011 0.92
57 Comparison of the RpoH-dependent regulon and general stress response in Neisseria gonorrhoeae. J Bacteriol 2006 0.92
58 Pore-forming activity of alpha-toxin is essential for clostridium septicum-mediated myonecrosis. Infect Immun 2009 0.89
59 The peptidoglycan hydrolase TcpG is required for efficient conjugative transfer of pCW3 in Clostridium perfringens. Plasmid 2012 0.89
60 Highly conserved alpha-toxin sequences of avian isolates of Clostridium perfringens. J Clin Microbiol 2004 0.88
61 Identification of the structural and functional domains of the large serine recombinase TnpX from Clostridium perfringens. J Biol Chem 2004 0.88
62 TcdB or not TcdB: a tale of two Clostridium difficile toxins. Future Microbiol 2011 0.88
63 Identification of essential residues in the Erm(B) rRNA methyltransferase of Clostridium perfringens. Antimicrob Agents Chemother 2002 0.88
64 Vaccination with recombinant NetB toxin partially protects broiler chickens from necrotic enteritis. Vet Res 2013 0.87
65 NetB, a pore-forming toxin from necrotic enteritis strains of Clostridium perfringens. Toxins (Basel) 2010 0.87
66 Two distinct regions of the large serine recombinase TnpX are required for DNA binding and biological function. Mol Microbiol 2006 0.87
67 S1 pocket of a bacterially derived subtilisin-like protease underpins effective tissue destruction. J Biol Chem 2011 0.87
68 Identification of a Dichelobacter nodosus ferric uptake regulator and determination of its regulatory targets. J Bacteriol 2005 0.86
69 Chloramphenicol-resistant Neisseria meningitidis containing catP isolated in Australia. J Antimicrob Chemother 2003 0.86
70 Cross-complementation of Clostridium perfringens PLC and Clostridium septicum alpha-toxin mutants reveals PLC is sufficient to mediate gas gangrene. Microbes Infect 2009 0.84
71 Regulation of sialidase production in Clostridium perfringens by the orphan sensor histidine kinase ReeS. PLoS One 2013 0.84
72 tISCpe8, an IS1595-family lincomycin resistance element located on a conjugative plasmid in Clostridium perfringens. J Bacteriol 2009 0.84
73 The cysteine protease α-clostripain is not essential for the pathogenesis of Clostridium perfringens-mediated myonecrosis. PLoS One 2011 0.84
74 Perfringolysin O expression in Clostridium perfringens is independent of the upstream pfoR gene. J Bacteriol 2002 0.83
75 Transformation-mediated serogroup conversion of Dichelobacter nodosus. Vet Microbiol 2003 0.82
76 Maternal immunization with vaccines containing recombinant NetB toxin partially protects progeny chickens from necrotic enteritis. Vet Res 2013 0.82
77 Virulence Plasmids of Spore-Forming Bacteria. Microbiol Spectr 2014 0.81
78 The Clostridium perfringens TetA(P) efflux protein contains a functional variant of the Motif A region found in major facilitator superfamily transport proteins. Microbiology 2004 0.81
79 Regulation of type IV fimbrial biogenesis in Dichelobacter nodosus. J Bacteriol 2006 0.80
80 The AprV5 subtilase is required for the optimal processing of all three extracellular serine proteases from Dichelobacter nodosus. PLoS One 2012 0.80
81 Crystallization of the virulent and benign subtilisin-like proteases from the ovine footrot pathogen Dichelobacter nodosus. Acta Crystallogr Sect F Struct Biol Cryst Commun 2010 0.79
82 Novel use of tryptose sulfite cycloserine egg yolk agar for isolation of Clostridium perfringens during an outbreak of necrotizing enterocolitis in a neonatal unit. J Clin Microbiol 2010 0.78
83 Utility of the clostridial site-specific recombinase TnpX to clone toxic-product-encoding genes and selectively remove genomic DNA fragments. Appl Environ Microbiol 2014 0.78
84 Isolation of the Bacteriophage DinoHI from Dichelobacter nodosus and its Interactions with other Integrated Genetic Elements. Open Microbiol J 2008 0.76
85 Methods for gene cloning and targeted mutagenesis. Methods Mol Biol 2010 0.76
86 Infectious disease: Listeria does it again. Nature 2010 0.75
87 Identification of a leukotoxin sequence from Fusobacterium equinum. Vet Microbiol 2008 0.75
88 Solution structure and DNA binding of the catalytic domain of the large serine resolvase TnpX. J Mol Recognit 2015 0.75