Published in DNA Seq on February 01, 2008
Epidemiological evidence for the links between sleep, circadian rhythms and metabolism. Obes Rev (2009) 1.83
Sleep timing and circadian phase in delayed sleep phase syndrome. J Biol Rhythms (2009) 0.91
Genotyping sleep disorders patients. Psychiatry Investig (2010) 0.85
Mutation of the Human Circadian Clock Gene CRY1 in Familial Delayed Sleep Phase Disorder. Cell (2017) 0.80
A genome-wide association study of bronchodilator response in asthmatics. Pharmacogenomics J (2013) 0.78
Season of birth, sex and sleep timing preferences. Int J Environ Res Public Health (2015) 0.75
PSMA6 (rs2277460, rs1048990), PSMC6 (rs2295826, rs2295827) and PSMA3 (rs2348071) genetic diversity in Latvians, Lithuanians and Taiwanese. Meta Gene (2014) 0.75
Gender effects of single nucleotide polymorphisms and miRNAs targeting clock-genes in metastatic colorectal cancer patients (mCRC). Sci Rep (2016) 0.75
Cumulative association of five genetic variants with prostate cancer. N Engl J Med (2008) 15.34
The Salmeterol Multicenter Asthma Research Trial: a comparison of usual pharmacotherapy for asthma or usual pharmacotherapy plus salmeterol. Chest (2006) 8.43
International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma. Eur Respir J (2013) 8.39
Identification of asthma phenotypes using cluster analysis in the Severe Asthma Research Program. Am J Respir Crit Care Med (2009) 7.17
Characterization of the severe asthma phenotype by the National Heart, Lung, and Blood Institute's Severe Asthma Research Program. J Allergy Clin Immunol (2007) 6.33
Tiotropium bromide step-up therapy for adults with uncontrolled asthma. N Engl J Med (2010) 6.19
Mepolizumab for severe eosinophilic asthma (DREAM): a multicentre, double-blind, placebo-controlled trial. Lancet (2012) 5.82
Two genome-wide association studies of aggressive prostate cancer implicate putative prostate tumor suppressor gene DAB2IP. J Natl Cancer Inst (2007) 4.85
Relationship between hours of CPAP use and achieving normal levels of sleepiness and daily functioning. Sleep (2007) 4.17
Identification of upper airway anatomic risk factors for obstructive sleep apnea with volumetric magnetic resonance imaging. Am J Respir Crit Care Med (2003) 4.14
Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. Nat Genet (2011) 3.68
Estrogen-receptor polymorphisms and effects of estrogen replacement on high-density lipoprotein cholesterol in women with coronary disease. N Engl J Med (2002) 3.68
Uniform definition of asthma severity, control, and exacerbations: document presented for the World Health Organization Consultation on Severe Asthma. J Allergy Clin Immunol (2010) 3.12
Lung function in adults with stable but severe asthma: air trapping and incomplete reversal of obstruction with bronchodilation. J Appl Physiol (1985) (2007) 2.83
Lethargus is a Caenorhabditis elegans sleep-like state. Nature (2008) 2.80
Germline mutations and sequence variants of the macrophage scavenger receptor 1 gene are associated with prostate cancer risk. Nat Genet (2002) 2.76
Gene-gene interaction in asthma: IL4RA and IL13 in a Dutch population with asthma. Am J Hum Genet (2001) 2.61
A randomized, double-blind, placebo-controlled study of tumor necrosis factor-alpha blockade in severe persistent asthma. Am J Respir Crit Care Med (2009) 2.56
Genome-wide association study of asthma identifies RAD50-IL13 and HLA-DR/DQ regions. J Allergy Clin Immunol (2010) 2.51
CPAP, weight loss, or both for obstructive sleep apnea. N Engl J Med (2014) 2.50
Identification of low-frequency variants associated with gout and serum uric acid levels. Nat Genet (2011) 2.48
Effect of ADRB2 polymorphisms on response to longacting beta2-agonist therapy: a pharmacogenetic analysis of two randomised studies. Lancet (2007) 2.41
Sleep deprivation selectively impairs memory consolidation for contextual fear conditioning. Learn Mem (2003) 2.34
Potential impact of adding genetic markers to clinical parameters in predicting prostate biopsy outcomes in men following an initial negative biopsy: findings from the REDUCE trial. Eur Urol (2012) 2.34
Heterogeneity of severe asthma in childhood: confirmation by cluster analysis of children in the National Institutes of Health/National Heart, Lung, and Blood Institute Severe Asthma Research Program. J Allergy Clin Immunol (2010) 2.27
Beta2-receptor polymorphisms in patients receiving salmeterol with or without fluticasone propionate. Am J Respir Crit Care Med (2009) 2.27
Association between genetic polymorphisms in the prostate-specific antigen gene promoter and serum prostate-specific antigen levels. J Natl Cancer Inst (2003) 2.26
Design and baseline characteristics of the epidemiology and natural history of asthma: Outcomes and Treatment Regimens (TENOR) study: a large cohort of patients with severe or difficult-to-treat asthma. Ann Allergy Asthma Immunol (2004) 2.22
Analyses of asthma severity phenotypes and inflammatory proteins in subjects stratified by sputum granulocytes. J Allergy Clin Immunol (2010) 2.20
Positive results in association studies are associated with departure from Hardy-Weinberg equilibrium: hint for genotyping error? Hum Genet (2002) 2.15
The pipeline of investigators for sleep research--a crisis! Sleep (2006) 2.04
Fine mapping and positional candidate studies identify HLA-G as an asthma susceptibility gene on chromosome 6p21. Am J Hum Genet (2004) 2.03
Problems associated with short sleep: bridging the gap between laboratory and epidemiological studies. Sleep Med Rev (2009) 1.97
A combined genomewide linkage scan of 1,233 families for prostate cancer-susceptibility genes conducted by the international consortium for prostate cancer genetics. Am J Hum Genet (2005) 1.96
Macromolecule biosynthesis: a key function of sleep. Physiol Genomics (2007) 1.93
Sequence variants of toll-like receptor 4 are associated with prostate cancer risk: results from the CAncer Prostate in Sweden Study. Cancer Res (2004) 1.91
Common estrogen receptor polymorphism augments effects of hormone replacement therapy on E-selectin but not C-reactive protein. Circulation (2002) 1.85
An association between L-arginine/asymmetric dimethyl arginine balance, obesity, and the age of asthma onset phenotype. Am J Respir Crit Care Med (2012) 1.85
Biomarker surrogates do not accurately predict sputum eosinophil and neutrophil percentages in asthmatic subjects. J Allergy Clin Immunol (2013) 1.80
Molecular signatures of obstructive sleep apnea in adults: a review and perspective. Sleep (2009) 1.76
Severe asthma: lessons learned from the National Heart, Lung, and Blood Institute Severe Asthma Research Program. Am J Respir Crit Care Med (2011) 1.76
Upper airway size analysis by magnetic resonance imaging of children with obstructive sleep apnea syndrome. Am J Respir Crit Care Med (2002) 1.75
Correlation of systemic superoxide dismutase deficiency to airflow obstruction in asthma. Am J Respir Crit Care Med (2005) 1.72
Pooled genome linkage scan of aggressive prostate cancer: results from the International Consortium for Prostate Cancer Genetics. Hum Genet (2006) 1.70
Association of a disintegrin and metalloprotease 33 (ADAM33) gene with asthma in ethnically diverse populations. J Allergy Clin Immunol (2003) 1.69
Gene expression in relation to exhaled nitric oxide identifies novel asthma phenotypes with unique biomolecular pathways. Am J Respir Crit Care Med (2014) 1.69
Occupational screening for obstructive sleep apnea in commercial drivers. Am J Respir Crit Care Med (2004) 1.68
Aging impairs the unfolded protein response to sleep deprivation and leads to proapoptotic signaling. J Neurosci (2008) 1.67
Promoter polymorphisms in the nitric oxide synthase 3 gene are associated with ischemic stroke susceptibility in young black women. Stroke (2005) 1.66
Variable-length poly-C tract polymorphisms of the beta2-adrenergic receptor 3'-UTR alter expression and agonist regulation. Am J Physiol Lung Cell Mol Physiol (2007) 1.66
A video method to study Drosophila sleep. Sleep (2008) 1.64
Recombination rates in admixed individuals identified by ancestry-based inference. Nat Genet (2011) 1.64
Obesity and asthma: an association modified by age of asthma onset. J Allergy Clin Immunol (2011) 1.64
Heart Failure and Sleep-Disordered Breathing--The Plot Thickens. N Engl J Med (2015) 1.63
Conservation of sleep: insights from non-mammalian model systems. Trends Neurosci (2008) 1.62
Single slice vs. volumetric MR assessment of visceral adipose tissue: reliability and validity among the overweight and obese. Obesity (Silver Spring) (2012) 1.60
Sequence, haplotype, and association analysis of ADRbeta2 in a multiethnic asthma case-control study. Am J Respir Crit Care Med (2006) 1.59
Comprehensive assessment of DNA copy number alterations in human prostate cancers using Affymetrix 100K SNP mapping array. Genes Chromosomes Cancer (2006) 1.58
Brain glycogen decreases with increased periods of wakefulness: implications for homeostatic drive to sleep. J Neurosci (2002) 1.58
Importance of hedgehog interacting protein and other lung function genes in asthma. J Allergy Clin Immunol (2011) 1.58
IL4R alpha mutations are associated with asthma exacerbations and mast cell/IgE expression. Am J Respir Crit Care Med (2006) 1.57
Dose effect of once-daily fluticasone furoate in persistent asthma: a randomized trial. Respir Med (2012) 1.57
Sequence variants in Toll-like receptor gene cluster (TLR6-TLR1-TLR10) and prostate cancer risk. J Natl Cancer Inst (2005) 1.55
Further replication studies of the EVE Consortium meta-analysis identifies 2 asthma risk loci in European Americans. J Allergy Clin Immunol (2012) 1.54
Risk factors for sleep-disordered breathing in pregnancy. Thorax (2013) 1.52
Genome-wide search for atopy susceptibility genes in Dutch families with asthma. J Allergy Clin Immunol (2002) 1.50
Major recessive gene(s) with considerable residual polygenic effect regulating adult height: confirmation of genomewide scan results for chromosomes 6, 9, and 12. Am J Hum Genet (2002) 1.47
The energy hypothesis of sleep revisited. Prog Neurobiol (2008) 1.47