Genetic polymorphisms and benzene metabolism in humans exposed to a wide range of air concentrations.

PubWeight™: 1.02‹?› | Rank: Top 15%

🔗 View Article (PMID 17885617)

Published in Pharmacogenet Genomics on October 01, 2007

Authors

Sungkyoon Kim1, Qing Lan, Suramya Waidyanatha, Stephen Chanock, Brent A Johnson, Roel Vermeulen, Martyn T Smith, Luoping Zhang, Guilan Li, Min Shen, Songnian Yin, Nathaniel Rothman, Stephen M Rappaport

Author Affiliations

1: School of Public Health, University of North Carolina, Chapel Hill, NC 27599, USA.

Articles citing this

Modulation of the metabolism of airborne pollutants by glucoraphanin-rich and sulforaphane-rich broccoli sprout beverages in Qidong, China. Carcinogenesis (2011) 1.12

Rapid and sustainable detoxication of airborne pollutants by broccoli sprout beverage: results of a randomized clinical trial in China. Cancer Prev Res (Phila) (2014) 1.11

Evidence that humans metabolize benzene via two pathways. Environ Health Perspect (2009) 1.03

Benzene exposure: an overview of monitoring methods and their findings. Chem Biol Interact (2010) 0.96

Low-dose metabolism of benzene in humans: science and obfuscation. Carcinogenesis (2012) 0.95

Diversity Outbred Mice Identify Population-Based Exposure Thresholds and Genetic Factors that Influence Benzene-Induced Genotoxicity. Environ Health Perspect (2014) 0.94

Genetic variation in metabolic genes, occupational solvent exposure, and risk of non-hodgkin lymphoma. Am J Epidemiol (2011) 0.87

Xenobiotic-Metabolizing gene polymorphisms and ovarian cancer risk. Mol Carcinog (2010) 0.86

The use of biomonitoring data in exposure and human health risk assessment: benzene case study. Crit Rev Toxicol (2013) 0.83

Human benzene metabolism following occupational and environmental exposures. Chem Biol Interact (2009) 0.81

Benzene Uptake and Glutathione S-transferase T1 Status as Determinants of S-Phenylmercapturic Acid in Cigarette Smokers in the Multiethnic Cohort. PLoS One (2016) 0.79

Metabolic Polymorphisms and Clinical Findings Related to Benzene Poisoning Detected in Exposed Brazilian Gas-Station Workers. Int J Environ Res Public Health (2015) 0.78

Benzene, cytochrome, carcinogenesis: A topic in preventive toxicology. Indian J Occup Environ Med (2014) 0.77

Benzene oxide is a substrate for glutathione S-transferases. Chem Biol Interact (2015) 0.77

Are polymorphisms in metabolism protective or a risk for reduced white blood cell counts in a Chinese population with low occupational benzene exposures? Int J Occup Environ Health (2015) 0.76

Applying a Weight-of-Evidence Approach to Evaluate Relevance of Molecular Landscapes in the Exposure-Disease Paradigm. Biomed Res Int (2015) 0.75

Microsomal epoxide hydrolase 1 (EPHX1): Gene, structure, function, and role in human disease. Gene (2015) 0.75

Articles by these authors

A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet (2012) 50.94

Genome-wide association study identifies novel breast cancer susceptibility loci. Nature (2007) 29.23

Assessing the probability that a positive report is false: an approach for molecular epidemiology studies. J Natl Cancer Inst (2004) 19.00

The state of US health, 1990-2010: burden of diseases, injuries, and risk factors. JAMA (2013) 10.43

Genomewide association study of leprosy. N Engl J Med (2009) 8.17

Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks in 188 countries, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet (2015) 7.99

A common coding variant in CASP8 is associated with breast cancer risk. Nat Genet (2007) 7.35

The Shanghai Women's Health Study: rationale, study design, and baseline characteristics. Am J Epidemiol (2005) 6.44

Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus. Nat Genet (2009) 6.42

Global, regional, and national disability-adjusted life years (DALYs) for 306 diseases and injuries and healthy life expectancy (HALE) for 188 countries, 1990-2013: quantifying the epidemiological transition. Lancet (2015) 6.13

Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses. Science (2011) 5.72

A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma. Am J Hum Genet (2009) 5.62

The Diesel Exhaust in Miners study: a nested case-control study of lung cancer and diesel exhaust. J Natl Cancer Inst (2012) 5.27

NAT2 slow acetylation, GSTM1 null genotype, and risk of bladder cancer: results from the Spanish Bladder Cancer Study and meta-analyses. Lancet (2005) 5.01

The Diesel Exhaust in Miners study: a cohort mortality study with emphasis on lung cancer. J Natl Cancer Inst (2012) 4.65

Epidemiology. Environment and disease risks. Science (2010) 4.64

A recurrent mutation in PALB2 in Finnish cancer families. Nature (2007) 4.64

A genome-wide association study identifies novel alleles associated with hair color and skin pigmentation. PLoS Genet (2008) 4.57

Associations of breast cancer risk factors with tumor subtypes: a pooled analysis from the Breast Cancer Association Consortium studies. J Natl Cancer Inst (2010) 4.54

Common variants at 19p13 are associated with susceptibility to ovarian cancer. Nat Genet (2010) 4.51

Epidemiology of myelodysplastic syndromes and chronic myeloproliferative disorders in the United States, 2001-2004, using data from the NAACCR and SEER programs. Blood (2008) 4.41

A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2. Nat Genet (2009) 4.38

Exposure to diesel motor exhaust and lung cancer risk in a pooled analysis from case-control studies in Europe and Canada. Am J Respir Crit Care Med (2010) 4.35

Hematotoxicity in workers exposed to low levels of benzene. Science (2004) 4.19

Genetic variation in TNF and IL10 and risk of non-Hodgkin lymphoma: a report from the InterLymph Consortium. Lancet Oncol (2006) 4.13

Genome-wide association study of circulating vitamin D levels. Hum Mol Genet (2010) 4.07

Improved identification of von Hippel-Lindau gene alterations in clear cell renal tumors. Clin Cancer Res (2008) 4.02

Mutation of GATA3 in human breast tumors. Oncogene (2004) 3.92

International patterns and trends in thyroid cancer incidence, 1973-2002. Cancer Causes Control (2008) 3.72

Detectable clonal mosaicism and its relationship to aging and cancer. Nat Genet (2012) 3.69

Genomic DNA hypomethylation as a biomarker for bladder cancer susceptibility in the Spanish Bladder Cancer Study: a case-control study. Lancet Oncol (2008) 3.60

SNP500Cancer: a public resource for sequence validation and assay development for genetic variation in candidate genes. Nucleic Acids Res (2004) 3.47

Population substructure and control selection in genome-wide association studies. PLoS One (2008) 3.44

A novel orally active proteasome inhibitor induces apoptosis in multiple myeloma cells with mechanisms distinct from Bortezomib. Cancer Cell (2005) 3.41

Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis. Nat Chem Biol (2012) 3.40

Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study. Nat Genet (2011) 3.07

Beyond odds ratios--communicating disease risk based on genetic profiles. Nat Rev Genet (2009) 3.01

Genome-wide and candidate gene association study of cigarette smoking behaviors. PLoS One (2009) 3.00

Counterpoint: bias from population stratification is not a major threat to the validity of conclusions from epidemiological studies of common polymorphisms and cancer. Cancer Epidemiol Biomarkers Prev (2002) 2.99

Genome-wide association study of renal cell carcinoma identifies two susceptibility loci on 2p21 and 11q13.3. Nat Genet (2010) 2.96

Risk of estrogen receptor-positive and -negative breast cancer and single-nucleotide polymorphism 2q35-rs13387042. J Natl Cancer Inst (2009) 2.88

Health and environmental consequences of the world trade center disaster. Environ Health Perspect (2004) 2.87

Tumor necrosis factor (TNF) and lymphotoxin-alpha (LTA) polymorphisms and risk of non-Hodgkin lymphoma in the InterLymph Consortium. Am J Epidemiol (2010) 2.86

Genetic variants at 6p21.33 are associated with susceptibility to follicular lymphoma. Nat Genet (2009) 2.73

Quality of evidence must guide risk assessment of asbestos. Ann Occup Hyg (2012) 2.68

Shortened telomere length is associated with increased risk of cancer: a meta-analysis. PLoS One (2011) 2.61

A quantitative approach for estimating exposure to pesticides in the Agricultural Health Study. Ann Occup Hyg (2002) 2.60

Smoking and risk for amyotrophic lateral sclerosis: analysis of the EPIC cohort. Ann Neurol (2009) 2.56

Etiologic heterogeneity among non-Hodgkin lymphoma subtypes. Blood (2008) 2.49

Night-shift work and breast cancer risk in a cohort of Chinese women. Am J Epidemiol (2010) 2.48

A prospective study of telomere length measured by monochrome multiplex quantitative PCR and risk of non-Hodgkin lymphoma. Clin Cancer Res (2009) 2.48

Recurrent inactivation of STAG2 in bladder cancer is not associated with aneuploidy. Nat Genet (2013) 2.44

Cancer survivorship--genetic susceptibility and second primary cancers: research strategies and recommendations. J Natl Cancer Inst (2006) 2.42

Analysis of PALB2/FANCN-associated breast cancer families. Proc Natl Acad Sci U S A (2007) 2.41

A case-control study of smoking and bladder cancer risk: emergent patterns over time. J Natl Cancer Inst (2009) 2.40

Comparison of expert and job-exposure matrix-based retrospective exposure assessment of occupational carcinogens in The Netherlands Cohort Study. Occup Environ Med (2012) 2.37

Genome-wide association study of follicular lymphoma identifies a risk locus at 6p21.32. Nat Genet (2010) 2.37

Improvement in household stoves and risk of chronic obstructive pulmonary disease in Xuanwei, China: retrospective cohort study. BMJ (2005) 2.36

Association of leukocyte telomere length with breast cancer risk: nested case-control findings from the Shanghai Women's Health Study. Am J Epidemiol (2013) 2.34

Occupational exposure to formaldehyde, hematotoxicity, and leukemia-specific chromosome changes in cultured myeloid progenitor cells. Cancer Epidemiol Biomarkers Prev (2010) 2.34

Tobacco smoking, NAT2 acetylation genotype and breast cancer risk. Int J Cancer (2006) 2.31

Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia. Nat Genet (2012) 2.26

STrengthening the Reporting of OBservational studies in Epidemiology--Molecular Epidemiology STROBE-ME: an extension of the STROBE statement. J Clin Epidemiol (2011) 2.24

Genome-wide association study identifies two susceptibility loci for osteosarcoma. Nat Genet (2013) 2.21

NAT2 slow acetylation and bladder cancer in workers exposed to benzidine. Int J Cancer (2006) 2.16

An emerging role for epigenetic dysregulation in arsenic toxicity and carcinogenesis. Environ Health Perspect (2010) 2.16

Genome-wide association studies, field synopses, and the development of the knowledge base on genetic variation and human diseases. Am J Epidemiol (2009) 2.15

The diesel exhaust in miners study: I. Overview of the exposure assessment process. Ann Occup Hyg (2010) 2.13