Oliver Eickelberg

Author PubWeight™ 126.22‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Cellular and molecular pathobiology of pulmonary arterial hypertension. J Am Coll Cardiol 2004 5.79
2 WNT1-inducible signaling protein-1 mediates pulmonary fibrosis in mice and is upregulated in humans with idiopathic pulmonary fibrosis. J Clin Invest 2009 3.33
3 Inhibition and role of let-7d in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 2010 3.02
4 Functional Wnt signaling is increased in idiopathic pulmonary fibrosis. PLoS One 2008 2.94
5 Genetics and genomics of pulmonary arterial hypertension. J Am Coll Cardiol 2009 2.31
6 Mutations of the TGF-beta type II receptor BMPR2 in pulmonary arterial hypertension. Hum Mutat 2006 2.30
7 Analysis of methylarginine metabolism in the cardiovascular system identifies the lung as a major source of ADMA. Am J Physiol Lung Cell Mol Physiol 2006 2.29
8 Retracted CXCR2 mediates NADPH oxidase-independent neutrophil extracellular trap formation in cystic fibrosis airway inflammation. Nat Med 2010 2.17
9 Biglycan, a danger signal that activates the NLRP3 inflammasome via toll-like and P2X receptors. J Biol Chem 2009 2.12
10 Increased local expression of coagulation factor X contributes to the fibrotic response in human and murine lung injury. J Clin Invest 2009 1.96
11 Activation of the WNT/β-catenin pathway attenuates experimental emphysema. Am J Respir Crit Care Med 2010 1.94
12 WNT signaling in lung disease: a failure or a regeneration signal? Am J Respir Cell Mol Biol 2009 1.90
13 Of flies, mice and men: a systematic approach to understanding the early life origins of chronic lung disease. Thorax 2012 1.88
14 The impact of TGF-β on lung fibrosis: from targeting to biomarkers. Proc Am Thorac Soc 2012 1.74
15 Hyperoxia modulates TGF-beta/BMP signaling in a mouse model of bronchopulmonary dysplasia. Am J Physiol Lung Cell Mol Physiol 2006 1.71
16 Conditional overexpression of bioactive transforming growth factor-beta1 in neonatal mouse lung: a new model for bronchopulmonary dysplasia? Am J Respir Cell Mol Biol 2004 1.67
17 Emphysema diagnosis using X-ray dark-field imaging at a laser-driven compact synchrotron light source. Proc Natl Acad Sci U S A 2012 1.62
18 Infiltrated neutrophils acquire novel chemokine receptor expression and chemokine responsiveness in chronic inflammatory lung diseases. J Immunol 2008 1.56
19 Caveolin-1 facilitates mechanosensitive protein kinase B (Akt) signaling in vitro and in vivo. Circ Res 2005 1.55
20 Genetic basis of pulmonary arterial hypertension: current understanding and future directions. J Am Coll Cardiol 2004 1.53
21 Increased expression of 5-hydroxytryptamine2A/B receptors in idiopathic pulmonary fibrosis: a rationale for therapeutic intervention. Thorax 2010 1.52
22 New cellular and molecular mechanisms of lung injury and fibrosis in idiopathic pulmonary fibrosis. Lancet 2012 1.47
23 Investigation of the antifibrotic effect of IFN-gamma on fibroblasts in a cell culture model of Peyronie's disease. Eur Urol 2007 1.47
24 Dysregulated bone morphogenetic protein signaling in monocrotaline-induced pulmonary arterial hypertension. Arterioscler Thromb Vasc Biol 2007 1.43
25 Leukocytes induce epithelial to mesenchymal transition after unilateral ureteral obstruction in neonatal mice. Am J Pathol 2007 1.39
26 Loss of RAGE in pulmonary fibrosis: molecular relations to functional changes in pulmonary cell types. Am J Respir Cell Mol Biol 2008 1.31
27 Chronic lung disease in the preterm infant. Lessons learned from animal models. Am J Respir Cell Mol Biol 2014 1.28
28 From arginine methylation to ADMA: a novel mechanism with therapeutic potential in chronic lung diseases. BMC Pulm Med 2009 1.24
29 TGF-beta signaling is dynamically regulated during the alveolarization of rodent and human lungs. Dev Dyn 2008 1.15
30 The angiotensin II receptor 2 is expressed and mediates angiotensin II signaling in lung fibrosis. Am J Respir Cell Mol Biol 2007 1.15
31 Lung-selective gene responses to alveolar hypoxia: potential role for the bone morphogenetic antagonist gremlin in pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol 2008 1.15
32 Transforming growth factor-beta signaling across ages: from distorted lung development to chronic obstructive pulmonary disease. Proc Am Thorac Soc 2009 1.14
33 Progressive pulmonary fibrosis is mediated by TGF-beta isoform 1 but not TGF-beta3. Int J Biochem Cell Biol 2007 1.11
34 Nrf2 induces interleukin-6 (IL-6) expression via an antioxidant response element within the IL-6 promoter. J Biol Chem 2010 1.09
35 Innovations in phenotyping of mouse models in the German Mouse Clinic. Mamm Genome 2012 1.09
36 Transgelin is a direct target of TGF-beta/Smad3-dependent epithelial cell migration in lung fibrosis. FASEB J 2008 1.09
37 Gli1 mediates lung cancer cell proliferation and Sonic Hedgehog-dependent mesenchymal cell activation. PLoS One 2013 1.08
38 Functional role and species-specific contribution of arginases in pulmonary fibrosis. Am J Physiol Lung Cell Mol Physiol 2007 1.07
39 Alveolar fluid clearance in acute lung injury: what have we learned from animal models and clinical studies? Intensive Care Med 2007 1.06
40 Pulmonary epithelium is a prominent source of proteinase-activated receptor-1-inducible CCL2 in pulmonary fibrosis. Am J Respir Crit Care Med 2008 1.06
41 Pulmonary emphysema diagnosis with a preclinical small-animal X-ray dark-field scatter-contrast scanner. Radiology 2013 1.05
42 Receptor for activated C-kinase 1, a novel interaction partner of type II bone morphogenetic protein receptor, regulates smooth muscle cell proliferation in pulmonary arterial hypertension. Circulation 2007 1.04
43 Acute cigarette smoke exposure impairs proteasome function in the lung. Am J Physiol Lung Cell Mol Physiol 2012 1.04
44 Tissue remodelling in chronic bronchial diseases: from the epithelial to mesenchymal phenotype. Eur Respir Rev 2014 1.04
45 Fhl-1, a new key protein in pulmonary hypertension. Circulation 2008 1.03
46 Transforming growth factor-beta-dependent growth inhibition in primary vascular smooth muscle cells is p38-dependent. J Pharmacol Exp Ther 2005 1.03
47 TGF-beta signaling in COPD: deciphering genetic and cellular susceptibilities for future therapeutic regimen. Swiss Med Wkly 2009 1.02
48 High throughput determination of TGFβ1/SMAD3 targets in A549 lung epithelial cells. PLoS One 2011 1.02
49 TGF-β directs trafficking of the epithelial sodium channel ENaC which has implications for ion and fluid transport in acute lung injury. Proc Natl Acad Sci U S A 2013 1.01
50 Regulation of TGF-beta ligand and receptor expression in neonatal rat lungs exposed to chronic hypoxia. J Appl Physiol (1985) 2002 1.00
51 Dysregulation of the IL-13 receptor system: a novel pathomechanism in pulmonary arterial hypertension. Am J Respir Crit Care Med 2010 1.00
52 Lysyl oxidase activity is dysregulated during impaired alveolarization of mouse and human lungs. Am J Respir Crit Care Med 2009 1.00
53 High mobility group N proteins modulate the fidelity of the cellular transcriptional profile in a tissue- and variant-specific manner. J Biol Chem 2013 0.95
54 Blue journal conference. Aging and susceptibility to lung disease. Am J Respir Crit Care Med 2015 0.94
55 The role of dimethylarginine dimethylaminohydrolase in idiopathic pulmonary fibrosis. Sci Transl Med 2011 0.94
56 Inflammatory and oxidative stress responses of an alveolar epithelial cell line to airborne zinc oxide nanoparticles at the air-liquid interface: a comparison with conventional, submerged cell-culture conditions. Biomed Res Int 2013 0.94
57 Paired immunoglobulin-like receptor-B inhibits pulmonary fibrosis by suppressing profibrogenic properties of alveolar macrophages. Am J Respir Cell Mol Biol 2013 0.93
58 The composition of cigarette smoke determines inflammatory cell recruitment to the lung in COPD mouse models. Clin Sci (Lond) 2014 0.93
59 Differential expression of matrix metalloproteinases and their inhibitors in human and mouse lung development. Thromb Haemost 2005 0.93
60 Increased protein arginine methylation in chronic hypoxia: role of protein arginine methyltransferases. Am J Respir Cell Mol Biol 2006 0.92
61 The chitinase-like protein YKL-40 modulates cystic fibrosis lung disease. PLoS One 2011 0.92
62 Overexpression of HSP-72 confers cytoprotection in experimental peritoneal dialysis. Kidney Int 2004 0.92
63 Cigarette smoke-induced disruption of bronchial epithelial tight junctions is prevented by transforming growth factor-β. Am J Respir Cell Mol Biol 2014 0.89
64 Role of von Hippel-Lindau protein in fibroblast proliferation and fibrosis. FASEB J 2011 0.89
65 Zyxin is a transforming growth factor-β (TGF-β)/Smad3 target gene that regulates lung cancer cell motility via integrin α5β1. J Biol Chem 2012 0.89
66 Diagnosing and mapping pulmonary emphysema on X-ray projection images: incremental value of grating-based X-ray dark-field imaging. PLoS One 2013 0.88
67 Plasminogen activator inhibitor type 1 inhibits smooth muscle cell proliferation in pulmonary arterial hypertension. Int J Biochem Cell Biol 2008 0.87
68 BDNF/TrkB signaling augments smooth muscle cell proliferation in pulmonary hypertension. Am J Pathol 2012 0.87
69 Upregulation of mRNA expression of MCP-1 by TGF-beta1 in fibroblast cells from Peyronie's disease. World J Urol 2008 0.87
70 Transcriptional and post-transcriptional regulation of transforming growth factor beta type II receptor expression in osteoblasts. Gene 2002 0.86
71 Alterations in the transforming growth factor (TGF)-beta pathway as a potential factor in the pathogenesis of Peyronie's disease. Eur Urol 2006 0.86
72 Improved diagnosis of pulmonary emphysema using in vivo dark-field radiography. Invest Radiol 2014 0.86
73 Multiplex profiling of cellular invasion in 3D cell culture models. PLoS One 2013 0.85
74 Identification of a novel IL-6 isoform binding to the endogenous IL-6 receptor. Am J Respir Cell Mol Biol 2002 0.85
75 In Vivo Dark-Field Radiography for Early Diagnosis and Staging of Pulmonary Emphysema. Invest Radiol 2015 0.84
76 Temporal and spatial regulation of bone morphogenetic protein signaling in late lung development. Dev Dyn 2007 0.84
77 Protease-mediated release of chemotherapeutics from mesoporous silica nanoparticles to ex vivo human and mouse lung tumors. ACS Nano 2015 0.84
78 Subcellular fractionation of TGF-beta1-stimulated lung epithelial cells: a novel proteomic approach for identifying signaling intermediates. Proteomics 2009 0.83
79 Efficient internalization and intracellular translocation of inhaled gold nanoparticles in rat alveolar macrophages. Nanomedicine (Lond) 2012 0.83
80 What shall we do with the damaged proteins in lung disease? Ask the proteasome! Eur Respir J 2012 0.83
81 Induction of mesothelial HSP-72 upon in vivo exposure to peritoneal dialysis fluid. Perit Dial Int 2003 0.83
82 Phosphodiesterase 6 subunits are expressed and altered in idiopathic pulmonary fibrosis. Respir Res 2010 0.82
83 Constitutive homo- and hetero-oligomerization of TbetaRII-B, an alternatively spliced variant of the mouse TGF-beta type II receptor. Biochem Biophys Res Commun 2006 0.82
84 Quantitative assessment of arginine methylation in free versus protein-incorporated amino acids in vitro and in vivo using protein hydrolysis and high-performance liquid chromatography. Biotechniques 2006 0.82
85 Mouse nuclear myosin I knock-out shows interchangeability and redundancy of myosin isoforms in the cell nucleus. PLoS One 2013 0.82
86 Cardiovascular and inflammatory effects of intratracheally instilled ambient dust from Augsburg, Germany, in spontaneously hypertensive rats (SHRs). Part Fibre Toxicol 2010 0.82
87 Mast cells mediate malignant pleural effusion formation. J Clin Invest 2015 0.82
88 Hypoxia differentially enhances the effects of transforming growth factor-beta isoforms on the synthesis and secretion of glycosaminoglycans by human lung fibroblasts. J Pharmacol Exp Ther 2002 0.82
89 [Pulmonary fibrosis--a therapeutic dilemma?]. Med Klin (Munich) 2006 0.81
90 Abca3 haploinsufficiency is a risk factor for lung injury induced by hyperoxia or mechanical ventilation in a murine model. Pediatr Res 2013 0.81
91 Efficient bioactive delivery of aerosolized drugs to human pulmonary epithelial cells cultured in air-liquid interface conditions. Am J Respir Cell Mol Biol 2014 0.80
92 Inflammatory responses to pulmonary application of PEI-based siRNA nanocarriers in mice. Biomaterials 2011 0.80
93 An American Thoracic Society Official Research Statement: Future Directions in Lung Fibrosis Research. Am J Respir Crit Care Med 2016 0.79
94 Worsening respiratory function in mechanically ventilated intensive care patients: feasibility and value of xenon-enhanced dual energy CT. Eur J Radiol 2012 0.79
95 The quest for the initial lesion in idiopathic pulmonary fibrosis: gene expression differences in IPF fibroblasts. Am J Respir Cell Mol Biol 2010 0.78
96 Dimethylarginine metabolism during acute and chronic rejection of rat renal allografts. Nephrol Dial Transplant 2010 0.78
97 Increased carcinogenic potential of myeloid tumor cells induced by aberrant TGF-beta1-signaling and upregulation of cathepsin B. Biol Chem 2007 0.78
98 The procoagulant effects of fine particulate matter in vivo. Part Fibre Toxicol 2011 0.78
99 An Official American Thoracic Society Workshop Report: Use of Animal Models for the Preclinical Assessment of Potential Therapies for Pulmonary Fibrosis. Am J Respir Cell Mol Biol 2017 0.77
100 Ventilation imaging of the paranasal sinuses using xenon-enhanced dynamic single-energy CT and dual-energy CT: a feasibility study in a nasal cast. Eur Radiol 2012 0.77
101 Transforming growth factor-alpha, a novel mediator of strain-induced vascular remodeling. Circ Res 2006 0.77
102 Epigenetic mechanisms in COPD: implications for pathogenesis and drug discovery. Expert Opin Drug Discov 2014 0.77
103 The tantalizing triplet of pulmonary hypertension-BMP receptors, serotonin receptors, and angiopoietins. Cardiovasc Res 2003 0.76
104 Platelet-derived growth factor signaling in the lung. From lung development and disease to clinical studies. Am J Respir Cell Mol Biol 2015 0.76
105 Characteristic patterns in the fibrotic lung. Comparing idiopathic pulmonary fibrosis with chronic lung allograft dysfunction. Ann Am Thorac Soc 2015 0.76
106 Have advanced research technologies made real impact on respiratory medicine? Respirology 2010 0.76
107 Exercise Reduces Lung Fibrosis Involving Serotonin/Akt Signaling. Med Sci Sports Exerc 2016 0.76
108 Human lung stem cells: oh, the places you'll go! EMBO Mol Med 2011 0.75
109 SFTA2--a novel secretory peptide highly expressed in the lung--is modulated by lipopolysaccharide but not hyperoxia. PLoS One 2012 0.75
110 Increased immunogenicity is an integral part of the heat shock response following renal ischemia. Cell Stress Chaperones 2011 0.75
111 Computer-aided diagnosis of pulmonary diseases using x-ray darkfield radiography. Phys Med Biol 2015 0.75
112 Correction: Noncanonical WNT-5A signaling impairs endogenous lung repair in COPD. J Exp Med 2017 0.75
113 Comparison of contrast-to-noise ratios of transmission and dark-field signal in grating-based X-ray imaging for healthy murine lung tissue. Z Med Phys 2012 0.75
114 Facilitated Diagnosis of Pneumothoraces in Newborn Mice Using X-ray Dark-Field Radiography. Invest Radiol 2016 0.75
115 Rebuilding a diseased lung: repair and regeneration. Eur Respir J 2013 0.75